Last reviewed: September 5, 2026 Last updated: September 22, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Director, with a PharmD and MBA specializing in pharmacogenomics and clinical product development. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

This article is part of the PlexusDx Education Hub — evidence-based guidance on GLP-1 therapies and weight-management care. Browse all Peptides & GLP-1 education

Editorial note: PlexusDx publishes this editorial review and offers one of the programs discussed. PlexusDx is not affiliated with MEDVi and has no commercial relationship with the companies named in this article; there are no affiliate links. Information is based on the sources and dates shown.

As of September 22, 2026, MEDVi's compounded semaglutide injection is $179 for the first month for new patients and $299 per billing cycle at refill, as displayed September 22, 2026. BrightMeds' landing pages list compounded semaglutide injection at $129/mo and compounded tirzepatide injection at $149/mo, the same in the first month and every month, at any dose, with 3-month packs of $297 (semaglutide) and $357 (tirzepatide). MEDVi's ongoing month-to-month rate for compounded tirzepatide injection is $399, verified September 22, 2026; MEDVi shows its tirzepatide first-month offer after the questionnaire. BrightMeds' offers are limited to listed states and show no end date, so verify whether they are time-limited before comparing. PlexusDx charges $189/mo for Semaglutide Injection and $289/mo for Tirzepatide Injection month-to-month.

Current semaglutide injection offers

MEDVi's structure has two numbers: the first-month rate on start.medvi.org and the refill rate on its program page, which renders prices by script. BrightMeds' structure has one monthly number plus an optional 3-month pack. Sources are MEDVi's program page and BrightMeds' landing pages; PlexusDx figures are from its product page.

PlexusDx publishes this comparison and offers one of the programs discussed. Information is based on the sources and dates shown.

Provider (compounded semaglutide injection) First payment Recurring month-to-month 3-month option Checked
MEDVi $179 first month (new patients) $299 per billing cycle, refill / recurring, as displayed September 22, 2026 3-, 6- and 12-month bundles offered; rates appear in MEDVi's signup flow and are not published here September 22, 2026
BrightMeds $129 (same as every month, per landing page) $129/mo, any dose; listed states only; end date not shown $297 per 3-month pack September 22, 2026
PlexusDx Semaglutide Injection $189 (no introductory rate; $0 until provider approval) $189/mo, flat across dose levels $169/mo advertised on a 3-month commitment; commitment total $507 September 22, 2026

Checked September 22, 2026. Month-to-month rates are the comparison basis; 3-month options are shown in their own column because they are commitments.

Compare PlexusDx plans

PlexusDx Weight Management Protocols: compounded semaglutide injection from $189/mo and tirzepatide injection from $289/mo month-to-month, all-inclusive (provider visit, prescription, medication, shipping). No membership fee. Flat price at every dose.

Compare PlexusDx plans → Start my PlexusDx intake →

Current tirzepatide injection offers

BrightMeds lists $149/mo at any dose with a $357 3-month pack. MEDVi's ongoing month-to-month rate for compounded tirzepatide injection is $399, verified September 22, 2026; refill-only cycles at that rate total 3 × $399 = $1,197, 6 × $399 = $2,394 and 12 × $399 = $4,788. MEDVi shows its tirzepatide first-month offer after the questionnaire; confirm it in the official offer, so no new-patient tirzepatide total is computed.

Provider (compounded tirzepatide injection) First payment Recurring month-to-month 3-month option Checked
MEDVi First-month offer shown after the questionnaire; confirm in MEDVi's official offer $399 per billing cycle, MEDVi's ongoing month-to-month rate, verified September 22, 2026 3-, 6- and 12-month bundles offered; rates appear in MEDVi's signup flow and are not published here September 22, 2026
BrightMeds $149 (same as every month, per landing page) $149/mo, any dose; listed states only; end date not shown $357 per 3-month pack September 22, 2026
PlexusDx Tirzepatide Injection $289 (no introductory rate; $0 until provider approval) $289/mo, flat across dose levels $269/mo advertised on a 3-month commitment; commitment total $807 September 22, 2026

Checked September 22, 2026. Compounded tirzepatide from any of these providers is not an FDA-approved drug product and is not the same as Zepbound® or Mounjaro®; the FDA's statement on unapproved GLP-1 drugs explains the distinction. BrightMeds separately offers branded Zepbound® through LillyDirect with a $100 consultation fee, which is a different product on a different price basis.

Refills and dose-price conditions

MEDVi states “same fair price at every dose” and says refills are locked at the refill price with the same program benefits. BrightMeds states its rate is the same first month and every month at any dose. PlexusDx states its monthly price is flat across every dose level for a compound and changes only with the commitment tier. The conditions differ elsewhere: BrightMeds' rates are on promotional landing pages restricted to listed states with no end date shown, so ask whether the rate you see is guaranteed at renewal. MEDVi does not publish its billing-cycle length, so this post counts cycles rather than calendar months. Dose changes themselves are decisions for the prescribing clinician.

Upfront commitments

MEDVi's first payment for semaglutide injection is $179; over three cycles a new patient pays $179 + 2 × $299 = $777, over six $1,674 and over twelve $3,468, our calculation from displayed rates. BrightMeds' 3-month packs are $297 for semaglutide and $357 for tirzepatide, paid for the pack; its month-to-month plan has no pack commitment. PlexusDx charges $0 until your provider approves, then the month-to-month rate; its commitment tiers are advertised per-month rates, with the payment schedule and any refund terms shown at checkout. For MEDVi's other products and the branded track, see MEDVi Cost: Semaglutide, Tirzepatide, Membership, and Plan Prices.

Inclusions and support

MEDVi lists the broader service package: physician review, a personalized plan, 1:1 guidance, a metabolic report, free dietitian visits and care coaching, unlimited 24/7 support, fast free shipping and HSA/FSA acceptance, with no membership fee on compounded programs. BrightMeds lists medication, evaluation, follow-up and shipping with no membership, a full refund if you are not approved, and cancellation anytime with 5 business days' notice before renewal. MEDVi's refund policy gives a full refund only within the first 72 hours without services or on medical disqualification, no refund for the month of cancellation, and requires 72 hours' notice before the next billing date. How customers describe MEDVi's support is covered in MEDVi customer reviews.

Which plan fits your budget?

If you live in a state BrightMeds lists and its rate holds at renewal, its published monthly figures are the lowest in this comparison for both injections. If you want dietitian visits and 24/7 support included and accept a refill that steps up after the first month, MEDVi publishes that package for semaglutide injection, and its compounded tirzepatide injection is $399 at MEDVi's ongoing month-to-month rate, verified September 22, 2026, with the first-month offer shown after the questionnaire. If you want one flat number from the first month with no state-limited offer to verify, PlexusDx publishes it on each product page. In every case, whether an injection is appropriate for you is decided by the licensed clinician who reviews your intake.

Where PlexusDx fits

PlexusDx's price covers the provider visit, prescription, medication and shipping in one monthly charge, with no membership fee, flat across every dose level, cancel anytime on month-to-month plans, and $0 until your provider approves. Compare PlexusDx weight-management plans or read the full MEDVi vs PlexusDx comparison.

A note on genetics (optional)

PlexusDx offers compounded semaglutide and tirzepatide through its Weight Management Protocols. Separately, and only if it interests you, the GLP-1 & Peptide Pathways Genetic Test ($298) analyzes 14 pathways, 49 peptides, 150+ genetic insights, including variants in FTO, MC4R and TCF7L2 that relate to appetite and glucose-handling pathways. It does not predict how you will respond to any medication and does not tell you which drug, dose or provider is right for you; it is context for a conversation with your clinician. Test before you invest, and treat genetics as a guide, not a guarantee.

This article is educational. PlexusDx is not affiliated with MEDVi and has no commercial relationship with the companies discussed. PlexusDx offers compounded semaglutide and tirzepatide through its own Weight Management Protocols; this article compares approaches in the GLP-1 telehealth space. The GLP-1 & Peptide Pathways Genetic Test analyzes how your genes influence peptide-related biological pathways. It does not predict response to any specific medication and does not recommend, prescribe, or determine which peptides you should use. Consult a qualified healthcare provider before beginning any peptide protocol. Compounded semaglutide and tirzepatide are not FDA-approved drug products; they are prepared by state-licensed compounding pharmacies under federal compounding rules and are not the same as Wegovy®, Ozempic®, Zepbound® or Mounjaro®. Zepbound® and Mounjaro® are registered trademarks of Eli Lilly and Company; Wegovy® and Ozempic® are registered trademarks of Novo Nordisk A/S. PlexusDx is not affiliated with or endorsed by either company.

Frequently Asked Questions

How much is semaglutide injection at MEDVi versus BrightMeds?

MEDVi's compounded semaglutide injection is $179 for the first month for new patients and $299 per billing cycle at refill, as displayed September 22, 2026. BrightMeds' landing pages list $129/mo, the same every month at any dose, or $297 per 3-month pack, in listed states only. Confirm both at checkout; MEDVi's price renders by script.

What does MEDVi charge for tirzepatide compared with BrightMeds?

BrightMeds lists compounded tirzepatide injection at $149/mo at any dose, or $357 per 3-month pack. MEDVi's ongoing month-to-month rate for compounded tirzepatide injection is $399, verified September 22, 2026; MEDVi shows its tirzepatide first-month offer after the questionnaire; confirm it in the official offer, and no new-patient total is computed. PlexusDx charges $289/mo for Tirzepatide Injection month-to-month, $110 a month less than MEDVi's ongoing rate.

Does the price go up when my dose increases?

Not according to either provider's published statements. MEDVi states the same price at every dose, BrightMeds states its rate applies at any dose, and PlexusDx states its monthly price is flat across every dose level for a compound. Whether and when a dose changes is a decision for the prescribing clinician, not something a price table settles.

Are BrightMeds' prices permanent or limited?

Unknown. BrightMeds' rates appear on promotional landing pages that show no end date and are limited to listed states, so whether the rate is guaranteed at renewal could not be verified. Ask BrightMeds in writing whether the monthly figure holds after the first renewal and confirm your state is eligible before comparing it with MEDVi's refill price.

What are the cancellation and refund rules for each?

MEDVi requires at least 72 hours' notice before the next billing date, refunds in full only within the first 72 hours without services or on medical disqualification, and does not refund the month of cancellation. BrightMeds allows cancellation anytime with 5 business days' notice before renewal and a full refund if you are not approved. PlexusDx month-to-month plans cancel anytime with no fees.

Sources and dates checked

Start my PlexusDx intake

A ~60-second intake. A licensed clinician in PlexusDx’s network reviews it and independently decides whether a prescription is appropriate. No charge unless your provider approves. Compare plans first: Compare PlexusDx plans.

Start my PlexusDx intake →

This article is part of the PlexusDx Education Hub. Browse all Peptides & GLP-1 education

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. Sources and the dates they were checked are listed at the end of the article.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services, and offers compounded GLP-1 programs through its Weight Management Protocols. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

Real prescribers. Published prices. No surprises.

Licensed providers in all 50 states. Online intake. No insurance, no membership required.

Start My Intake →

~60 seconds · $0 charged until your provider approves