Energy and cellular health
NAD+, glutathione, MIC + B12 and Lipo C injections
Start online visitLongevity Protocols
Seven compounded longevity protocols, prescribed by licensed providers.
Use code GETSTARTED for 10% off your first order. New patients, first order only.
Does not apply to genetic tests, blood tests, or supplements.

7 PROTOCOLS
7 compounds
GENETICS
17 insights · $99 add-on
Overview
PlexusDx offers seven prescription longevity protocols — NAD+, Glutathione, MIC + B12, Lipo C, Sermorelin, GHK-Cu Rx, and PT-141. Every price is published on its product page before you enroll.
Every prescription is written by a licensed provider in your state, with no membership fee stacked on top of medication — so the protocol works for your biology, your goals, and how you want to feel about how you’re aging.
The optional GLP-1 & Peptide Pathways Genetic Test analyzes 17 Longevity insights including FOXO3 — a longevity gene linked to living past 100 — with crossover into Energy Metabolism, Tissue Repair, and Cognition pathways. Drawn from a 150+ insight panel across 14 pathways. Available for $99 as an add-on after your first month of treatment.
Choose a 1-, 3-, 6- or 12-month plan. 3-, 6- and 12-month plans are charged once, up front, and renew automatically until you cancel future renewals.
NAD+, glutathione, MIC + B12 and Lipo C injections
Start online visitSermorelin injection
Start online visitGHK-Cu cream
Start online visitPT-141 (bremelanotide) injection, for women and men
Start online visitYour provider decides whether a medication is right for you.
Seven compounded longevity protocols across four online visits. Your price depends on your plan length.
Energy and cellular health
A coenzyme your cells use to make energy. Injection.
Starts at $119/mo12-month plan
Your body’s master antioxidant. Injection.
Starts at $69/mo12-month plan
Methionine, inositol, choline and B12. Injection.
Starts at $69/mo12-month plan
Lipotropics plus L-carnitine. Injection.
Starts at $109/mo12-month plan
Sleep and recovery
Asks your body to make more of its own growth hormone. Injection.
Starts at $119/mo12-month plan
Skin
Copper peptide cream, 0.2%, 0.5% or 2%.
Starts at $59/mo12-month plan
Sexual health
Melanocortin receptor agonist. Injection.
Starts at $159/mo12-month plan
| Medication | 1 month | 3 months | 6 months | 12 months | |
|---|---|---|---|---|---|
| LongevityStart | |||||
| NAD+ | Most prescribed | $159/mo | $139/mo$417 up front | $129/mo$774 up front | $119/mo$1,428 up front |
| Glutathione | $99/mo | $89/mo$267 up front | $79/mo$474 up front | $69/mo$828 up front | |
| MIC + B12 | $99/mo | $89/mo$267 up front | $79/mo$474 up front | $69/mo$828 up front | |
| Lipo CMIC, L-carnitine, B-complex and B12 | $139/mo | $129/mo$387 up front | $119/mo$714 up front | $109/mo$1,308 up front | |
| SermorelinStart | |||||
| Sermorelin | $159/mo | $139/mo$417 up front | $129/mo$774 up front | $119/mo$1,428 up front | |
| GHK-CuStart | |||||
| GHK-Cu cream 0.2% | $89/mo | $79/mo$237 up front | $69/mo$414 up front | $59/mo$708 up front | |
| GHK-Cu cream 0.5% | $99/mo | $89/mo$267 up front | $79/mo$474 up front | $69/mo$828 up front | |
| GHK-Cu cream 2% | $129/mo | $119/mo$357 up front | $109/mo$654 up front | $99/mo$1,188 up front | |
| PT-141Start | |||||
| PT-141 | Trending | $189/mo | $179/mo$537 up front | $169/mo$1,014 up front | $159/mo$1,908 up front |
Each protocol, plain English: how it works, who it's for.
BasicsYour cells run on NAD+. Prescription injection.
Made forPeople focused on energy and mental clarity.
BasicsYour body already makes growth hormone. Sermorelin asks it to make more.
Made forPeople focused on sleep and recovery.
BasicsYour body's master antioxidant. Prescription injection.
Made forPeople focused on energy and recovery.
BasicsYour metabolism runs on four sparks. One shot, all four.
Made forPeople focused on energy and metabolism.
Every protocol is prescribed by a licensed provider.
What longevity at PlexusDx is
PlexusDx longevity is a medically-supervised category: seven prescription protocols prescribed by licensed providers and shipped from a 503A pharmacy partner.
Three things define the category at PlexusDx, and together they’re what makes longevity care something you can build a decade around, not a one-off trend.
Pillar 01
Every protocol is reviewed and prescribed by a licensed provider in your state. No chatbot intake, no AI rx, no template-driven script. Clinical decisions stay with clinicians.
Pillar 02
Compounded at a 503A state-licensed pharmacy partner, prepared individually for your prescription, and shipped to your door. No marketplace, no third-party reseller, no surprise substitutions.
Pillar 03
The optional GLP-1 & Peptide Pathways Genetic Test gives you 17 Longevity insights, including FOXO3, to share with your provider.
Category at a glance
7 protocols
NAD+, Glutathione, MIC + B12, Lipo C, Sermorelin, GHK-Cu Rx, PT-141
Personalized care
17 insights
GLP-1 & Peptide Pathways Genetic Test, including FOXO3 longevity markers
Coverage
Telehealth
Online visit, no clinic visit required
Each longevity medication comes in one form: an injection, or a cream for GHK-Cu.
| Compound | Injection | Topical cream |
|---|---|---|
| NAD+Most prescribed | ✓ | — |
| Sermorelin | ✓ | — |
| Glutathione | ✓ | — |
| MIC + B12 | ✓ | — |
| Lipo C | ✓ | — |
| GHK-Cu Rx | — | ✓ |
| PT-141 | ✓ | — |
NAD+
Most prescribedSermorelin
Glutathione
MIC + B12
Lipo C
GHK-Cu Rx
PT-141
— Start here
Foundational reading — six pillars before you commit to a protocol.
Pillar 01
The 14 pathways, 49 peptides, 150+ insights explained.
Read article →
Pillar 02
Inside the engine that turns SNPs into pathway insights.
Pillar 03
DNA + blood + supervised protocols — how the layers fit.
Pillar 04
What $99 of DNA tells you about your biology.
Pillar 05
A field guide to your dashboard, in plain English.
Read article →
Pillar 06
What DNA testing can — and can’t — tell you about peptides.
Read article →
— What makes PlexusDx different
PlexusDx analyzes 14 peptide-related pathways across 49 peptides. Two ways to get your insights: one for new customers, one for everyone already on file.
New customer path
Order the GLP-1 & Peptide Pathways Genetic Test — at-home cheek swab, CLIA-certified lab analysis, and a personalized 17-insight longevity report including FOXO3.
17
Longevity insights
across 14 pathways
Existing customer path
Already have your DNA on file? Buy any additional pathway report for $29.99 — activates immediately in your Results Portal, no re-test needed.
$29.99
Per pathway report
activates immediately
Process
Browse seven prescription protocols and start the online visit for the area you want to work on first.
A short online visit about your goals and health history.
A licensed provider reviews your online visit and decides whether a medication is right for you. Real medical authority, no AI prescriptions.
Compounded by a 503A pharmacy, then shipped by UPS 2nd Day Air.
Who longevity care at PlexusDx is for
Every protocol is reviewed by a licensed provider in your state. Eligibility is set clinically, not by a chatbot. Here’s who fits the program — and who doesn’t.
Who’s a fit
You’re an adult 18 or older interested in proactive healthy-aging care — energy, cellular repair, cognitive resilience, or longevity-pathway optimization.
You want medical supervision and ongoing monitoring, not a one-time prescription drop.
You have no active malignancy, no current pregnancy, no severe hepatic or renal disease, and no known hypersensitivity to compounded peptide therapy.
You’re committed to lifestyle support alongside medication — nutrition, movement, sleep.
Who’s not a fit
You’re under 18. Our protocols are for adults only.
You’re pregnant, breastfeeding, or trying to conceive — compounded peptide therapy is not appropriate during these life stages.
You have active malignancy, severe hepatic or renal disease, or known hypersensitivity to compounded peptide therapy. Compound-specific exclusions also apply: uncontrolled hypertension or recent cardiovascular event (PT-141).
You’re looking for a one-time prescription with no follow-up. We’re built for the long game — provider check-ins and titration, not a single fill-and-go transaction.
What’s included
Every longevity protocol at PlexusDx ships with the same six service inclusions. No hidden fees and no platform fee layered on top of the protocol price. Optional add-ons — like the GLP-1 & Peptide Pathways Genetic Test — are clearly marked, never auto-added.
Real medical authority, no AI prescriptions
A board-licensed clinician reviews your intake and writes the script. No chatbot, no algorithmic approval.
Compounded medication shipped from a licensed 503A pharmacy
Your prescription is filled by a state-licensed compounding pharmacy and shipped directly to your door.
Ongoing clinical check-ins across your protocol cycle
Your provider monitors response, side effects, and progress — and adjusts your dose if needed within the same protocol.
Manage your plan in your patient portal
Pause a delivery or update your shipping address in your patient portal at my.plexusdx.com. Cancel future renewals anytime.
Plain-label shipments. No branding on the outer box.
No sender name visible from the porch. No category language on the box. Patient privacy preserved at the curb.
Add the genetic test as a $99 add-on after your first month
150+ insights across 14 pathways. Optional, never required — your provider decides care without it.
— The library
Three curated tracks. Five articles each. Choose the cluster that fits your question and read at your own pace before you talk to a provider.
Longevity-specific
Five reads on your longevity genes, from FOXO3 to NAD+ and sirtuin pathways.
The complete guide to genetic longevity testing: 17 pathway insights
Read article →
The FOXO3 longevity gene: what your results mean
Read article →
Can I increase NAD+ based on my genetics?
What is the longevity-aging pathway in genetic testing?
The SIRT1 pathway: genetics, NAD+, and cellular repair
Read article →
Cross-family
Five bridges into methylation, cognition, and growth-hormone-axis territory — because longevity rarely sits on its own.
MTHFR and longevity: are they connected? What the science shows
Methylation and longevity: how MTHFR shapes your aging pathway
Read article →
APOE genotypes and healthy aging: a deep dive
Read article →
Growth hormone axis genetics: IGF1, GHSR, and aging
Read article →
Mitochondrial function and genetics: the cellular energy story
Peptide pathways
The most-extracted articles from the Longevity and Lifespan library, drawn from the 17 longevity pathway posts.
Frequently asked
Questions on choosing a visit and plan, pricing, providers, refills, the optional genetic test, safety and combining protocols.
Visits + plans
Which online visit should I start?
Start with the area you want to work on first. For energy and cellular health, start the Longevity visit; for sleep and recovery, the Sermorelin visit; for skin, the GHK-Cu visit; for sexual health, the PT-141 visit. A licensed provider reviews each visit and decides whether a medication is right for you.
What does the Longevity visit cover?
One Longevity visit covers four prescription injections: NAD+, glutathione, MIC + B12 and Lipo C. On a 12-month plan, glutathione and MIC + B12 start at $69/mo ($828 billed up front), Lipo C at $109/mo and NAD+ at $119/mo. Your provider decides which, if any, is right for you.
How much does sermorelin cost?
Sermorelin injections start at $119/mo on a 12-month plan, billed as $1,428 up front. Month to month, sermorelin is $159. Start the Sermorelin visit, and a licensed provider decides whether sermorelin is right for you.
How much does GHK-Cu cream cost?
GHK-Cu copper peptide cream comes in 0.2%, 0.5% and 2% strengths. On a 12-month plan, the 0.2% cream starts at $59/mo, billed as $708 up front; 0.5% starts at $69/mo and 2% at $99/mo. Month to month, the 0.2% cream is $89. Your provider decides whether GHK-Cu is right for you.
How much does PT-141 cost?
PT-141 (bremelanotide) injections start at $159/mo on a 12-month plan, billed as $1,908 up front. Month to month, PT-141 is $189. One PT-141 visit serves women and men, and your provider decides whether PT-141 is right for you.
How do the 1-, 3-, 6- and 12-month plans work?
Choose a 1-, 3-, 6- or 12-month plan. 3-, 6- and 12-month plans are charged once, up front, and renew automatically until you cancel future renewals. There is no membership fee.
Can I use my HSA or FSA card, or pay over time?
Yes. HSA and FSA cards accepted at checkout. Pay over time on 3-, 6- and 12-month plans. The 1-month plan does not offer pay over time. You choose how to pay at checkout.
Who decides whether a medication is right for me?
A licensed provider reviews your online visit and decides whether a medication is right for you. Choosing a visit starts that review; it does not guarantee a prescription. The medications on this page are prescription only.
Already a patient? Where do I log in?
Log in to your patient portal at my.plexusdx.com. The buttons on this page each start a new online visit, so use one only when you want a provider to review you for a different medication.
About the protocol
The medically supervised prescription model, and what makes it different from other telehealth programs.
What is a PlexusDx longevity protocol?
A PlexusDx longevity protocol is a medically supervised prescription plan that includes a licensed provider’s review, your medication compounded by a 503A pharmacy, ongoing provider monitoring and shipping. Seven protocol options are available: NAD+, Glutathione, MIC + B12, Lipo C, Sermorelin, GHK-Cu Rx and PT-141.
How is PlexusDx longevity care different from other telehealth peptide programs?
PlexusDx pairs every protocol with an optional genetic test few telehealth programs offer, publishes every price up front, and uses real medical authority: licensed providers, not AI prescriptions.
Where are PlexusDx longevity protocols available?
PlexusDx longevity protocols are prescribed through an independent network of U.S.-licensed clinicians on a state-licensed telehealth platform. Your provider confirms availability in your state at your visit and, depending on your state or health history, may ask for a phone or video visit.
Eligibility + getting started
Who PlexusDx longevity protocols are designed for, and how to start the right online visit.
Am I eligible for a longevity protocol?
You’re eligible if you’re an adult 18 or older interested in proactive healthy-aging care. You must have no active malignancy, no current pregnancy, no severe hepatic or renal disease, and no known hypersensitivity to compounded peptide therapy. Compound-specific exclusions apply: uncontrolled hypertension or recent cardiovascular event (PT-141).
How do I get started?
Start the online visit for the goal you want to work on first, from the buttons on this page. A licensed provider reviews it, and cards are charged once your prescription is sent to the pharmacy.
Do I need blood work to start a longevity protocol?
Blood work is not clinically required for any PlexusDx longevity protocol. Your provider may request labs based on your individual medical history, but the online visit does not require a blood draw.
Pricing + billing
Compound-level pricing with full transparency. The price you see in the price table is the price you pay.
How much does a PlexusDx longevity protocol cost?
Longevity medications run $89 to $189 a month on a 1-month plan, and $59 to $159 a month on a 12-month plan, billed once up front. Your price depends on the medication and your plan length.
What’s included in the price?
Your price covers your licensed provider’s review, your medication compounded by a 503A pharmacy, ongoing provider monitoring and shipping. The optional GLP-1 & Peptide Pathways Genetic Test is a $99 add-on available after your first month, never auto-added and never required to start a protocol.
Medication + pharmacy
503A compounded medication, prepared by licensed pharmacies in response to your individual prescription.
Where does my longevity medication come from?
Your medication is compounded by a licensed 503A pharmacy in response to your individual prescription. 503A pharmacies are state-board-regulated facilities that prepare patient-specific compounded medications under strict USP standards. Compounded medications are not FDA-approved.
How is my medication shipped?
After your provider approves your prescription, the pharmacy typically prepares and ships it within 3 to 5 business days, by UPS 2nd Day Air, with no shipping charge. Plain-label shipments: no sender name or category language on the outer box. Tracking is provided through your patient portal.
Provider care
Licensed providers and ongoing review: real medical authority, no AI prescriptions.
Will I work with a real licensed provider?
Yes. Every PlexusDx longevity protocol is prescribed and monitored by a licensed provider in our independent clinician network: real medical authority, not AI prescriptions. Your provider reviews your online visit, writes your prescription and monitors your response.
How often will I communicate with my provider?
Your provider reviews your online visit before prescribing, and you can message your care team through your patient portal at any time. A prescription generally covers up to six months of treatment; continuing after that needs a new provider review.
Refills + ongoing protocol
How renewals, dose changes and pauses work.
How do refills work?
Your plan renews automatically at the same length until you cancel future renewals, and the pharmacy ships each refill to your door. Your provider sets your supply.
Can I request a dose adjustment from my provider?
Yes. Request a dose change through your patient portal; your provider reviews the request and decides. For the same medication and plan, your price does not change with your dose, except for GHK-Cu cream, which is priced by strength.
Can I pause my protocol and resume later?
Yes. Pause a delivery or update your shipping address in your patient portal at my.plexusdx.com. You can pause for 1 to 12 months at a time, and resuming may need a provider review.
Genetic test add-on
Optional, never required. Your provider decides care without it.
What does the GLP-1 & Peptide Pathways Genetic Test analyze?
The GLP-1 & Peptide Pathways Genetic Test analyzes 150+ genetic insights across 14 pathways — including 17 insights specific to longevity, with FOXO3 as the featured longevity gene. The test analyzes how your genes influence peptide-related biological pathways. It does not recommend, prescribe, or determine which peptides you should use — that is your provider’s clinical decision.
When can I add the genetic test?
The genetic test is available as a $99 add-on after your first month of any PlexusDx protocol. Already a customer with your DNA on file? Add any single pathway report for $29.99 — activates immediately in your Results Portal, no re-test needed. The test is optional and never required to start a longevity protocol.
Does the genetic test predict which peptide will work for me?
No. The GLP-1 & Peptide Pathways Genetic Test analyzes how your genes influence longevity-related biological pathways, including FOXO3, a longevity gene linked to living past 100. It does not recommend, prescribe, or determine which peptides you should use, and does not predict drug response to any specific compound. Consult your provider before beginning any peptide protocol.
Side effects + safety
Compound-specific exclusions, side effect monitoring, and what to do if you have a concern.
What are the side effects of longevity compounds?
Side effects vary by compound. NAD+ may cause flushing or transient nausea; Sermorelin may cause injection-site reactions; PT-141 may cause headache, nausea, or transient blood pressure changes. Your provider reviews each compound’s specific side effect profile during intake and monitors your response. Discuss any concerns through your patient portal.
What contraindications should I know about?
Active malignancy, current pregnancy, severe hepatic or renal disease, and known hypersensitivity to compounded peptide therapy are exclusions for the longevity protocol family. Compound-specific exclusions: uncontrolled hypertension or recent cardiovascular event (PT-141). Your provider screens for these during intake.
What do I do if I have an emergency or urgent concern?
For any medical emergency, call 911 or go to your nearest emergency room. For urgent non-emergency concerns related to your protocol, message your provider through your patient portal. For routine questions or side-effect monitoring, the portal message thread is the primary care channel.
Cancel + change protocol
Cancel future renewals anytime.
How do I cancel my protocol?
Cancel future renewals anytime: turn off automatic renewal under Manage subscription in your patient portal at my.plexusdx.com before your next renewal charge. You keep the treatment you have already paid for. Canceling stops your next renewal; it does not refund the rest of a prepaid plan.
Can I switch from one longevity compound to another?
Yes, if your provider approves it. Request a switch through your patient portal. Unused prepaid value is applied as a credit toward the new medication, which uses its own plan price.
What happens to my genetic test data if I cancel?
Your genetic test data and Results Portal access remain available after cancellation. The GLP-1 & Peptide Pathways Genetic Test is a one-time purchase, so your insights stay in your portal indefinitely. If you return to PlexusDx later, your existing genetic profile applies to any new protocol without re-testing.
Cross-protocol stacking
When longevity care can run alongside another PlexusDx protocol — and when it can’t.
Can I run a longevity protocol alongside a weight management protocol?
Sometimes. Some longevity compounds run safely alongside weight management protocols; others do not. Your provider determines whether stacking is clinically appropriate based on your medical history, current medications, and the specific compounds involved. Request a stacking review through your patient portal — do not start a second protocol without provider authorization.
Does running multiple protocols at once cost more or get a bundle discount?
Each protocol you run is billed at its own published price for your plan length. PlexusDx does not currently offer bundle discounts on stacked protocols. You can cancel future renewals on one protocol without affecting the others.
Ready when you are
12-month plan
Published prices on every compound
Cancel future renewals anytime. No membership fee.
Health markers you can measure. Energy and aging goals that matter.
Both belong in the same protocol — backed by licensed prescribers and a 503A pharmacy.