THE BENEFITS

What Sermorelin actually does for you.

WHAT CHANGES

Your body already knows how to grow. Sermorelin asks it to do more.

Your body makes less growth hormone every year after 30. Less GH means lighter sleep, slower recovery, softer body. Sermorelin nudges your own system to make more — on your body's natural rhythm.

WHAT YOU'LL FEEL

Show up to your day differently

Deeper sleep at night. Faster recovery between hard training. A body that bounces back instead of grinding.

HOW LONG IT TAKES

Real results take real time

Sermorelin builds over weeks, not days. Most people feel deeper sleep by week four to six. Recovery and body composition shift over the next two months. Your provider checks in every month and adjusts your plan as you go.

WHY IT WORKS FOR YOU

Built around your biology, not someone else's average

Sermorelin response varies by genetics. The optional Precision Peptide Genetic Test analyzes 17 Longevity insights including FOXO3 so your protocol gets shaped around your body.

PEER-REVIEWED RESEARCH

29

Amino-acid peptide representing the shortest fully bioactive fragment of growth hormone-releasing hormone (GHRH). Source: Walker, Vascular Health and Risk Management, 2006.

Compounded medications are not FDA-approved or evaluated for safety, effectiveness, or quality. PlexusDx coordinates care; licensed providers evaluate and prescribe when clinically appropriate; partner pharmacies dispense and label medications.

READY?

Feel the difference your provider designs around you.

Coming Soon

This protocol is launching soon. Check back shortly.

Overview

Compounded Sermorelin is a GHRH analog peptide prescribed by licensed providers in injection or oral troche formulations. Provider-selected delivery at provider-determined dosing. One monthly price covers your provider visit, prescription, medication, and shipping — $155 to $189 per month, all-inclusive, depending on commitment tier. No membership fee. Eligible adults across all 50 states.

  • Two provider-selected formulations — subcutaneous injection or oral disintegrating troche — at provider-determined dosing
  • GHRH analog mechanism — stimulates endogenous growth hormone release for recovery, sleep quality, and lean mass
  • $155 to $189 per month all-inclusive across 3 commitment tiers — covers consult, prescription, compounded medication, shipping
  • Real medical authority — licensed providers in your state, no AI prescriptions
  • 17 Longevity genetic insights including FOXO3 — optional Precision Peptide Genetic Test, $99 as an add-on after your first month

The optional Precision Peptide Genetic Test analyzes 17 Longevity insights including FOXO3 — the most-studied longevity gene, linked to centenarian populations and cellular repair capacity — with crossover into Energy Metabolism, Tissue Repair, and Cognition pathways. Drawn from a 150+ insight panel across 14 pathways. Available for $99 as an add-on after your first month of treatment.

Why trust PlexusDx

Compliance

503A pharmacy-grade medication

Your compounded Sermorelin is prepared by a licensed 503A compounding pharmacy for your prescription — not mass-manufactured.

Coverage

Licensed providers in all 50 states

Available in all 50 states. Five states require a scheduled video consultation — your provider advises.

Privacy

HIPAA-compliant platform

Protected under HIPAA. Never sold or shared without your consent. Results delivered securely through the PlexusDx Results Portal.

Pricing

One transparent price

All-inclusive. Your dose may need to go up. Your price won't.

Telehealth across the US — see state availability below

Pricing

What you pay

Your dose may need to go up. Your price won't.

Starts at $155 /mo

All-inclusive. No membership. Cancel anytime.

Choose your commitment tier

Month-to-month

$189/mo

3-month

$169/mo
Best value

6-month

$155/mo

Provider-selected formulation, no price impact

Injection
ODT
Async provider intake Rx issuance Compounded Sermorelin Direct shipping

Provider-determined dosing

Your provider reviews your intake and selects your starting protocol — formulation, dose, and tier guidance. Available in all 50 states async. Sermorelin Injection and Sermorelin Acetate (sublingual) both ship to all 50 states.

WHAT HAPPENS NEXT

After you order

What happens once your intake is in.

Same day

LICENSED REVIEW

Provider review & prescription

A licensed US provider reviews your intake, selects the compound, and writes your prescription.

3–5 business days

503A COMPOUNDING

Pharmacy ships your medication

Your compounded Sermorelin ships from a US 503A pharmacy in your provider-selected formulation. A 503A pharmacy is a state-licensed compounding facility regulated by FDA and state boards of pharmacy that prepares medications individually for a specific patient based on a valid prescription. Dosing schedule included.

Every month

CARE THAT CONTINUES

Ongoing provider care

Unlimited provider messaging, dose adjustments, and clinical check-ins.

Anytime

FLEXIBILITY

Cancel anytime, no fees

Cancel anytime — no fees, no contracts. Your provider reviews each refill.

OUR COMMITMENT

Nothing is charged until your provider approves your prescription. Cancel anytime, no fees.

EVERYTHING INCLUDED

What's included

Your provider, your pharmacy, your direct-to-door shipping — everything in your monthly Sermorelin Protocol protocol.

PROVIDER

Licensed, async

Licensed providers in all 50 states. Most patients reviewed within one business day.

PHARMACY

503A compounded

Pharmacy-grade Sermorelin prepared for your provider-selected formulation.

SHIPPING

Direct-to-door

Discreet packaging. Ships from U.S. partner pharmacy.

ALL-INCLUSIVE

One all-inclusive price

Provider, prescription, medication, and shipping — in one monthly charge. No membership.

WHAT YOU WON'T PAY
Membership fee
Consult charge
Hidden fees
REFILLS

Provider-reviewed

Each refill re-authorized by your provider. Not auto-shipped.

MONITORING

Monthly check-ins

Provider check-ins to assess response and adjust formulation as needed.

FLEXIBILITY

Cancel anytime

No long-term contract. Pause or stop between refills.

Optional add-on
Available post-enrollment

The optional Precision Peptide Genetic Test analyzes 17 Longevity insights including FOXO3 — the most-studied longevity gene, linked to centenarian populations and cellular repair capacity — drawn from a 150+ insight panel across 14 pathways. Available for $99 as an add-on after your first month of treatment.

17
Pathway insights
150+
Total panel
14
Pathways
$99
Add-on
Featured SNP
FOXO3
the most-studied longevity gene, linked to centenarian populations and cellular repair capacity

CLINICAL FIT CHECK

Is this protocol right for you?

We lead with safety considerations first. If any exclusion applies to you, stop here and speak with your primary care provider before starting intake.

SAFETY EXCLUSIONS

Skip this protocol if…

MALIGNANCY HISTORY

Active or recent malignancy diagnosis

PREGNANCY STATUS

Pregnancy or breastfeeding

ORGAN DISEASE

Acute critical illness or recent surgery

SAFETY

Known hypersensitivity to sermorelin or excipients

ELIGIBLE

You're a fit if…

AGE & SYMPTOMS

Adults 30+ noticing slower recovery, sleep, or lean-mass changes

CLINICAL OVERSIGHT

Want licensed provider oversight across all 50 states

PRICING TRANSPARENCY

Want one all-inclusive price with no hidden fees

DATA-GUIDED CARE

You prefer clinical decisions informed by your personal health data

PROVIDER VERDICT

Your licensed provider confirms final eligibility during intake review. No medication ships without their sign-off.

Built differently

What makes PlexusDx different

Five things every shopper deserves before they sign up.

THE DIFFERENTIATOR

Genetics-informed care from a complete precision health platform

17 Longevity insights via the Precision Peptide Genetic Test — across 14 pathways, 49 peptides. The only telehealth peptide protocol with a genetic testing layer.

TRANSPARENCY

Radically transparent

Every dose level and every price published.

PRICING

All-inclusive

One price for intake, Rx, medication, shipping.

CLINICAL

Async clinical oversight

No in-person visits. Available in all 50 states.

NO GATE

No membership gate

Your first dollar goes toward care, not a subscription.

Clinical details

Clinical details

How this compound works and what lab work is involved.

Compound spec

Class

GHRH analog

Growth-hormone-releasing hormone analog peptide


Route

Injection or oral

Subcutaneous inj. or sublingual troche


Half-life

Provider-set

cadence depends on formulation


Compounded by

503A pharmacy

licensed US partner

How it works

About this compound

Sermorelin is a 29-amino-acid analog of growth hormone-releasing hormone (GHRH) that stimulates the pituitary gland's natural release of growth hormone in pulses mirroring endogenous physiology.

Your provider selects your Sermorelin formulation (subcutaneous injection or Acetate ODT) and dose during intake review. Pricing is structured in three commitment tiers from $155 to $189 per month, all clinically supervised.

See how PlexusDx customers describe their precision health journey — read Customer Stories.

Why it matters

Aging response varies by genetics. The optional Precision Peptide Genetic Test analyzes 17 Longevity insights including FOXO3 — the most-studied longevity gene, linked to centenarian populations and cellular repair capacity. Available for $99 as an add-on after your first month of treatment.

Lab requirements
No blood work required at intake. Blood testing is available at patient election and may be recommended by your provider based on your individual health history. At-home blood collection is available through Red Drop Dx — no clinic visit required.
NOT REQUIRED
Compare Compounds

How this compound compares

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Route
Starts at
NAD+
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You're viewingSermorelin
GHRH analog
Injection / oral
$155/mo
MIC B12
Lipotropic cofactor
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Glutathione
Endogenous antioxidant
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$129/mo
Methylene Blue
Mitochondrial cofactor
Capsule
$149/mo
GHK-Cu Rx
Copper-binding tripeptide
Topical cream
$169/mo
Lipo C
Lipotropic + antioxidant injection
Injection
$199/mo
PT-141
Melanocortin receptor agonist
Injection
$219/mo

Sermorelin Protocol — FAQ

Answers before you start

Straight answers on pricing, formulation, and what's included — pulled from the questions Longevity patients ask most.

PRICING

What does my monthly price include?

Sermorelin is priced by commitment tier — month-to-month $189, 3-month $169, and 6-month $155 (best value). All three tiers include async provider consultation, prescription, compounded Sermorelin in your provider-selected formulation, and shipping. No membership fee, no per-formulation surcharge.

INCLUSIONS

What arrives in my monthly package?

Every monthly charge includes async provider consultation and intake review, your prescription written by a licensed provider in your state, compounded Sermorelin medication in the formulation your provider selected, and free discreet shipping in all 50 states. Refills are provider-reviewed and authorized through your portal — no separate re-intake required unless your formulation or tier changes.

FORMULATION

How does formulation selection work — who decides which form I receive?

Your provider selects your Sermorelin formulation during intake review based on your clinical goals, tolerance, and preference. Both formulations — injection and oral acetate ODT — deliver the same GHRH-analog mechanism to the same growth-hormone-axis pathway. Injection is the most direct delivery route; oral ODT is the non-injectable alternative. Switching formulations later is possible with provider approval.

MECHANISM

What is Sermorelin and how does it support longevity?

Sermorelin is a GHRH analog — a peptide that stimulates your pituitary gland to release growth hormone in your body's natural pulsatile pattern. Endogenous growth hormone supports cellular repair, lean muscle preservation, sleep quality, and recovery — mechanisms that decline with age. Sermorelin is intended to support physiologic GH-axis activity rather than supplement growth hormone directly — a core mechanism in clinical longevity protocols.

GENETICS

Do I need my Precision Peptide Genetic Test before starting?

No — the Precision Peptide Genetic Test is optional and available as a $99 add-on after your first month of treatment. Your provider can prescribe Sermorelin based on standard intake without genetic data. The test analyzes 14 pathways, 49 peptides, and 150+ genetic insights — including 17 Longevity-Aging insights with FOXO3 — providing additional context that may inform formulation choice or long-term protocol adjustments.

FLEXIBILITY

What if I need a different formulation, tier, or compound?

You can switch Sermorelin formulations with provider approval — for example, moving from injection to oral ODT for travel convenience. Tier upgrades adjust your billing automatically. If your provider recommends a different longevity compound (NAD+, MIC B12, or others), they can switch your prescription and your billing updates to reflect the new compound. No fees to switch.

─── READY TO START

Start your Sermorelin protocol today

Three reasons to start your longevity protocol with PlexusDx.

ENROLL TODAY
Ready to start your Sermorelin protocol?

Order your Sermorelin protocol today. Gain access to 17 Longevity-Aging genetic insights post-enrollment, including FOXO3. Make informed decisions supported by clinical oversight and your unique biology.

Coming Soon
~60 second intake · $0 until Rx approved
TRANSPARENCY
Every formulation, every price
Published before you enroll. No intake required to see prices.
Radically transparent
ALL-INCLUSIVE
One price, all-in
Intake, Rx, medication, and shipping — one monthly price.
No surprise billing
GENETICS-INFORMED
Your biology, your care
150+ insights across 14 pathways, available post-enrollment for $99.
The only telehealth layer
Important Information
Compounded medications are not approved by the FDA or reviewed for quality, safety, or efficacy.

Novo Nordisk, Inc. is the only United States company with FDA-approved products containing semaglutide, identified under the trade names Rybelsus®, Ozempic®, and Wegovy®.

Lilly USA LLC is the only United States company with FDA-approved products containing tirzepatide, identified under the trade names Zepbound® and Mounjaro®.

The Precision Peptide Genetic Test analyzes how your genes influence peptide-related biological pathways. It does not recommend, prescribe, or determine which peptides you should use. Consult a qualified healthcare provider before beginning any peptide protocol.