Genetic testing doesn't treat sexual dysfunction — it maps the biological terrain that every treatment decision operates within. The Precision Peptide Genetic Test delivers 6 Sexual Health insights across 14 pathways, 49 peptides, and 150+ genetic insights, giving providers the upstream biological context that bloodwork alone cannot supply — and changing the clinical conversation before any protocol begins.

In the Precision Peptide Genetic Test, the Sexual Health pathway delivers 6 insights across the genes governing central arousal, vascular sexual response, desire, bonding, and circadian sexual timing. Part of 14 pathways, 49 peptides, and 150+ genetic insights, these 6 variants map sexual biology as a connected system — not a checklist of isolated traits.

PDE5 pathway support compounds work differently for different men because the upstream signal they amplify — eNOS-derived nitric oxide — is genetically variable. NOS3 genotype sets the vascular floor. The Precision Peptide Genetic Test maps this and other pathway variables across 14 pathways, 49 peptides, and 150+ genetic insights, explaining the response variability that dosing alone cannot.

Libido has a genetic architecture — DRD2 receptor density, OXTR bonding sensitivity, MTNR1B circadian timing, and MC4R central arousal signaling all shape sexual desire at the neurochemical level. The Precision Peptide Genetic Test maps these variables as part of 14 pathways, 49 peptides, and 150+ genetic insights, explaining the biology of desire that testosterone panels miss.

Yes — eNOS genetics directly shapes the nitric oxide foundation that vascular sexual response is built on. NOS3 variants determine how much NO your endothelium produces per arousal signal. The Precision Peptide Genetic Test analyzes eNOS variants as part of 14 pathways, 49 peptides, and 150+ genetic insights, answering the question bloodwork alone cannot.

Erectile function depends on multiple gene-governed systems — nitric oxide production, central arousal signaling, dopamine-driven desire, and cGMP preservation. The Precision Peptide Genetic Test maps the key variants across 14 pathways, 49 peptides, and 150+ genetic insights, identifying the genetic architecture that testosterone panels and vascular tests alone cannot reveal.

Sexual wellness has a genetic architecture — six biological variables that determine how your body produces arousal, routes blood flow, generates desire, and responds to intimacy. The Precision Peptide Genetic Test maps all six as part of 14 pathways, 49 peptides, and 150+ genetic insights, answering the question that hormone panels and bloodwork alone cannot.

The vasoactive pathway governs genital blood flow through multiple parallel mechanisms — nitric oxide, prostaglandin signaling, and alpha-adrenergic tone — each with its own genetic variable. The Precision Peptide Genetic Test maps key vasoactive pathway variants as part of 14 pathways, 49 peptides, and 150+ genetic insights, revealing the full vascular architecture that sexual arousal depends on.

Central sexual arousal — the brain-driven signal that initiates the entire sexual response cascade — runs through the melanocortin pathway and its primary receptor, MC4R. The Precision Peptide Genetic Test analyzes melanocortin pathway variants as part of 14 pathways, 49 peptides, and 150+ genetic insights, mapping the CNS architecture of arousal that vascular testing cannot reach.

PDE5 pathway support works differently for different people — and genetics is one of the most direct explanations for that variability. The Precision Peptide Genetic Test maps upstream NOS3 and downstream pathway variables as part of 14 pathways, 49 peptides, and 150+ genetic insights, explaining the vascular dimension of differential response.

OXTR encodes the oxytocin receptor that governs bonding, arousal facilitation, and the neurochemistry of intimacy in both men and women. The Precision Peptide Genetic Test analyzes OXTR variants as part of 14 pathways, 49 peptides, and 150+ genetic insights — mapping the social bonding dimension of sexual health that hormone panels cannot measure.

DRD2 encodes the D2 dopamine receptor that governs the motivation, anticipation, and reward dimensions of sexual desire. The Precision Peptide Genetic Test analyzes DRD2 variants as part of 14 pathways, 49 peptides, and 150+ genetic insights — mapping the neurochemical foundation of sexual drive that no testosterone panel captures.

MTNR1B encodes the melatonin receptor that governs circadian regulation of testosterone, autonomic tone, and the timing of sexual function. The Precision Peptide Genetic Test analyzes MTNR1B variants as part of 14 pathways, 49 peptides, and 150+ genetic insights — mapping the chronobiological dimension of sexual health that no blood test captures.

eNOS — the endothelial nitric oxide synthase enzyme encoded by NOS3 — is the genetic starting point of the vascular cascade that sexual arousal depends on. The Precision Peptide Genetic Test analyzes NOS3 variants as part of 14 pathways, 49 peptides, and 150+ genetic insights, mapping the upstream NO signal before it reaches the PDE5 pathway.

The Precision Peptide Genetic Test analyzes 6 Sexual Health insights covering the four systems behind sexual response — vascular (eNOS, PDE5), dopamine (DRD2), bonding (OXTR), and circadian (MTNR1B) — within 14 pathways, 49 peptides, and 150+ genetic insights. This pillar breaks down what each gene reveals and why sexual health is a multi-system problem.

Yes — genetic testing can guide hormone replacement, but "guide" means something more precise than "predict" or "prescribe." The Precision Peptide Genetic Test maps six Reproductive Health insights across 14 pathways, 49 peptides, and 150+ genetic insights that give providers and patients a defined biological starting point before any hormone support protocol begins.

In the Precision Peptide Genetic Test, the Reproductive Health pathway delivers 6 insights across the genes governing estrogen Phase 1 metabolism, Phase 2 clearance, methylation supply, and receptor sensitivity. Part of 14 pathways, 49 peptides, and 150+ genetic insights, these 6 variants map women's estrogen biology as a connected system — not a checklist of isolated traits.

HRT works differently for every woman because the biological systems that process estrogen are individually variable — and genetics is the layer that explains those differences most precisely. The Precision Peptide Genetic Test maps six variables across 14 pathways, 49 peptides, and 150+ genetic insights that determine how your body handles any hormone support protocol.

MTHFR variants affect HRT in three ways: by constraining the SAMe supply that estrogen clearance depends on, by elevating homocysteine as a cardiovascular monitoring variable, and by determining which folate form will actually support your methylation cycle on protocol. The Precision Peptide Genetic Test analyzes MTHFR as part of 14 pathways, 49 peptides, and 150+ genetic insights.

Yes — COMT Val158Met directly shapes estrogen clearance speed, and slow COMT genotypes can contribute to the functional estrogen accumulation associated with estrogen dominance. The Precision Peptide Genetic Test analyzes COMT as part of 14 pathways, 49 peptides, and 150+ genetic insights — revealing your clearance baseline before symptoms or protocols make it relevant.

Multiple genes shape estrogen levels in women — from production through metabolism to clearance and receptor response. The Precision Peptide Genetic Test analyzes the key variants across 14 pathways, 49 peptides, and 150+ genetic insights, giving providers the genetic picture that estradiol blood tests alone cannot deliver.

The Precision Peptide Genetic Test maps the genetic variables that shape how you experience the menopause transition — from vasomotor symptom intensity to bone density trajectory to mood changes. Part of 14 pathways, 49 peptides, and 150+ genetic insights, your Reproductive Health panel explains why menopause feels profoundly different from one woman to the next.

The Precision Peptide Genetic Test analyzes GSTM1 and GSTT1 — the glutathione S-transferase genes whose null deletions eliminate the tertiary Phase 2 backstop against reactive estrogen quinones. Part of 14 pathways, 49 peptides, and 150+ genetic insights, your GSTM1 and GSTT1 deletion status determines whether glutathione conjugation is available when COMT and SULT1A1 clearance is insufficient.

Two women begin the same hormone support protocol on the same day. Weeks later, one feels significantly better — symptoms eased, energy restored. The other notices little change or unwanted effects. The Precision Peptide Genetic Test maps six biological variables across 14 pathways and 150+ genetic insights that explain this gap — not chance, but genetics.

The Precision Peptide Genetic Test analyzes SULT1A1 — the sulfotransferase enzyme that runs a methylation-independent route to estrogen clearance. Part of 14 pathways, 49 peptides, and 150+ genetic insights, your SULT1A1 Arg213His genotype determines how quickly sulfation neutralizes estradiol and its metabolites for excretion — a parallel Phase 2 pathway that COMT genetics alone cannot capture.

The Precision Peptide Genetic Test analyzes ESR1 and ESR2 — the two estrogen receptor genes that determine how sensitively your tissues respond to circulating estrogen. Part of 14 pathways, 49 peptides, and 150+ genetic insights, your estrogen receptor variants explain why the same estradiol level produces very different biological effects in different women.

The Precision Peptide Genetic Test analyzes MTHFR C677T and A1298C — the variants that set your methylation capacity and determine how efficiently your body produces the SAMe that estrogen clearance depends on. Part of 14 pathways, 49 peptides, and 150+ genetic insights, MTHFR is the upstream genetic variable that connects the methylation cycle to women's hormone balance.

The Precision Peptide Genetic Test analyzes COMT Val158Met — the single variant that most directly determines how quickly your body clears catechol estrogens in Phase 2 metabolism. Part of 14 pathways, 49 peptides, and 150+ genetic insights, your COMT genotype explains why two women with identical estrogen levels can experience hormonal balance very differently.

The Precision Peptide Genetic Test analyzes CYP1A1 and CYP1B1 — the two Phase 1 enzymes that determine which metabolic route estradiol takes after it leaves circulation. Part of 14 pathways, 49 peptides, and 150+ genetic insights, your CYP1A1 and CYP1B1 variants set the 2-OHE2 to 4-OHE2 ratio that shapes your estrogen biology from the inside out.

The Precision Peptide Genetic Test analyzes 6 Reproductive Health insights covering women's hormone pathways — COMT, CYP1A1, CYP1B1, MTHFR, ESR1, and Phase 2 detox genes — within a panel of 14 pathways, 49 peptides, and 150+ genetic insights. This pillar guide breaks down how you produce, clear, and respond to estrogen, and why clearance genetics matter as much as production.