About PlexusDx
General questions about who we are and what we offer.
PlexusDx is a precision wellness company offering at-home genetic tests, blood tests, and personalized supplements. Tests are processed in CLIA-certified laboratories and results are delivered through the PlexusDx Results Portal. PlexusDx is designed for individuals who want data-driven insights to guide nutrition, supplement, and lifestyle decisions — without requiring a doctor's order.
PlexusDx offers three product categories: genetic tests that analyze DNA to reveal insights about health, nutrition, and wellness; at-home blood tests that measure current biomarker levels; and personalized supplement packs recommended based on your test results. Bundles combining genetic and blood tests are also available for deeper personalization.
No. PlexusDx is a wellness and education company. All tests are designed for educational and personal health optimization purposes and are not intended to diagnose, treat, cure, or prevent any disease or medical condition. Results should be used alongside — not as a replacement for — guidance from a qualified healthcare provider.
Yes. All PlexusDx samples are processed in CLIA-certified laboratories. CLIA (Clinical Laboratory Improvement Amendments) certification is the federal standard for laboratory quality and accuracy. Genetic tests use validated DNA analysis methods, and blood tests follow clinical accuracy standards consistent with those used in medical settings.
PlexusDx is designed for adults who want to understand how their genetics and current biomarker levels influence their health, nutrition, and wellness. Tests are also available for minors with parental consent and registration completed through customer support. PlexusDx is not designed for individuals seeking a medical diagnosis or emergency health guidance.
How At-Home Testing Works
From order to results — everything you need to know about the process.
You order your test online, receive a collection kit by mail, collect your sample at home using the included instructions, and return it to the lab using the prepaid mailer. No doctor's visit or prescription is required. Once your sample is processed, results are delivered securely to your PlexusDx Results Portal.
No. All PlexusDx tests can be purchased directly without a doctor's order or prescription. While no referral is required, PlexusDx recommends sharing your results with a qualified healthcare provider for clinical interpretation and any treatment decisions, particularly before making changes to medications or supplement protocols.
For genetic tests, you collect a cheek swab using the swab included in your kit. For blood tests, you collect a small fingerstick sample using the lancet and collection card included. Both kits contain step-by-step instructions. Once collected, mail your sample to the lab using the prepaid return mailer included in your kit.
Results are delivered to your PlexusDx Results Portal at plexusdx.com. You will receive an email notification when results are ready. The Portal organizes your genetic reports, blood test results, personalized recommendations, and supplement suggestions in one place. Results remain available in your Portal indefinitely.
Yes. You can purchase any PlexusDx test for another person. The recipient will need to activate the test kit on the PlexusDx website upon receipt. For individuals under 18, parental or guardian consent is required during kit activation, which must be completed through PlexusDx customer support.
Genetic Tests
Questions about DNA-based testing, what's included, and how results work.
A PlexusDx genetic test analyzes your DNA using a cheek swab to reveal genetic insights related to health, nutrition, metabolism, hormones, detoxification, and more. Results are organized into detailed reports delivered through your Results Portal. Tests are a one-time purchase — your DNA does not change, so results remain relevant for life.
The number of insights varies by test. The Functional Health Genetic Test includes over 1,000 insights across multiple health categories. Focused tests like the Genetic Methylation Test include over 300 insights. Each insight is tied to specific genetic variants and includes an evidence-based explanation and practical guidance. Individual product pages list exact insight counts.
No. Because your DNA does not change, a PlexusDx genetic test is a one-time purchase — results remain relevant for your entire lifetime. PlexusDx recommends pairing genetic results with periodic blood testing to track how current biomarker levels interact with your genetic tendencies and how they respond to lifestyle changes over time.
No. PlexusDx genetic tests are designed for educational and wellness purposes and are not diagnostic. They do not diagnose, treat, or predict disease risk. Results reveal genetic tendencies that may influence nutrition, metabolism, and overall health — and are intended to inform personal wellness decisions in consultation with a healthcare provider, not replace clinical care.
Genetic test results are typically available within 3–4 weeks after the laboratory receives your sample. Processing time begins when the lab receives the sample, not when you mail it. You will receive an email notification when results are ready in your PlexusDx Results Portal.
Yes. Genetic tests may be taken by minors. However, test kit registration for individuals under 18 must be completed through PlexusDx customer support rather than the standard online registration process, and a parent or guardian must provide consent. Contact support@tests.plexusdx.com or call 877-760-2333 to complete registration for a minor.
Genetic Reports
Questions about add-on digital reports that expand your genetic insights.
A Genetic Report is a digital add-on that uses existing PlexusDx DNA data to deliver deeper insights on a specific health topic — such as methylation, detoxification, fitness, hormones, or longevity. Reports are purchased separately and unlocked instantly in your Results Portal. A completed PlexusDx genetic test is required to access any Genetic Report.
A Genetic Test includes a physical collection kit, laboratory processing, and a set of bundled reports. A Genetic Report is a digital add-on that uses DNA data already collected from a completed test — no new sample or lab processing is required. Reports are available instantly after purchase and delivered directly to your Results Portal.
Genetic Reports are typically available within moments of purchase and appear directly in your PlexusDx Results Portal. Availability outside business hours may take slightly longer. A completed PlexusDx genetic test is required — reports cannot be unlocked without existing DNA data on file from a prior test.
PlexusDx currently offers 11 Genetic Reports covering: Allergies & Food Sensitivities, Cardiometabolic Health, Cognition & Brain Health, Detoxification, Diet & Nutrition, Fitness & Injury, Healthy Aging, Longevity & Lifespan, Men's Hormone & Fertility Health, Methylation Pathway, Weight & Body Fat, and Women's Hormone & Fertility Health.
Blood Tests
Questions about at-home blood testing, biomarkers, and results.
PlexusDx at-home blood tests measure current biomarker levels using a small fingerstick blood sample collected at home and mailed to a CLIA-certified laboratory. Unlike genetic tests, which reveal lifelong DNA tendencies, blood tests show what is happening in your body right now — making them ideal for ongoing monitoring and tracking changes over time.
Blood samples are collected using a fingerstick lancet included in your test kit. You prick your fingertip, collect a small sample on the collection card, allow it to dry, and mail it to the laboratory using the prepaid return mailer. The kit includes clear step-by-step instructions. No clinic visit, venipuncture, or medical professional is required.
Most blood test results are available within 1–2 business days after the laboratory receives your sample. Hormone and fertility panels — including the Women's Hormone and Women's Fertility tests — typically take up to 5 business days. You will receive an email notification when results are ready in your PlexusDx Results Portal.
No. PlexusDx blood tests are designed for wellness and educational purposes and are not intended to diagnose, treat, or monitor any medical condition. Results provide insight into current biomarker levels to inform personal wellness decisions. Any results of clinical concern should be reviewed with a qualified healthcare provider.
Yes, and PlexusDx recommends it. Blood biomarkers change in response to diet, supplements, lifestyle, and other factors. Repeating blood tests allows you to track how levels shift in response to changes guided by your PlexusDx recommendations. Optional subscription delivery every 4 weeks is available for all blood tests to support ongoing monitoring.
Supplements
Questions about how PlexusDx personalized supplement packs work.
PlexusDx supplements are targeted nutrient packs recommended based on your genetic test results and blood biomarker data. All formulas are doctor-formulated, third-party tested for purity and potency, and manufactured in cGMP-certified facilities. Supplements are selected through your PlexusDx Results Portal based on your individual data — not sold as generic one-size-fits-all products.
Your PlexusDx Results Portal analyzes your genetic insights and blood biomarker results to identify specific nutrient needs and gaps. Only supplements aligned with your individual data are recommended. Recommendations may update as new blood test results are added, allowing your supplement protocol to evolve as your health data changes over time.
All PlexusDx supplements are doctor-formulated, third-party tested, and manufactured in cGMP-certified facilities to verify ingredient quality, purity, and potency. As with any supplement protocol, individuals who are pregnant, nursing, taking prescription medications, or managing health conditions should consult a healthcare provider before beginning supplementation.
Supplements can be purchased without testing, but PlexusDx recommends using test results to guide selection. Without test data, supplement recommendations cannot be personalized to your individual needs. The Results Portal provides the context and reasoning behind each recommendation — purchasing supplements without it means bypassing the personalization the PlexusDx system is built to deliver.
Ordering, Payment & HSA/FSA
Questions about purchasing, payment methods, insurance, and FSA/HSA eligibility.
No. All PlexusDx genetic tests, blood tests, and supplements can be purchased directly online without a doctor's order or prescription. While no referral is required, PlexusDx recommends sharing your results with a healthcare provider for clinical interpretation — particularly before making changes to medications or treatment plans.
Yes. PlexusDx has partnered with Flex to accept Health Savings Account (HSA) and Flexible Spending Account (FSA) payments at checkout. Using pre-tax HSA or FSA funds typically results in net savings of 30–40% depending on your tax bracket. At checkout, select "Flex | Pay with HSA/FSA" as your payment method.
Add products to your cart and proceed to checkout. Select "Flex | Pay with HSA/FSA" as your payment option and enter your HSA or FSA debit card. If you do not see this option, you may be logged into Shop Pay — select "checkout as guest" to access all payment methods. If your card is unavailable, pay with a credit card and Flex will email an itemized receipt for reimbursement submission.
PlexusDx does not bill health insurance directly. However, you may submit a claim to your insurer for potential reimbursement — PlexusDx cannot guarantee coverage. HSA and FSA funds accepted at checkout via Flex are typically the most straightforward path to using pre-tax dollars for wellness testing purchases.
The most common reason for HSA/FSA card declines is insufficient funds. Contact your HSA or FSA administrator to verify your available balance. If funds are insufficient, enter a credit card on the Flex checkout page — Flex will provide an itemized receipt and Letter of Medical Necessity to submit to your HSA or FSA administrator for reimbursement.
No. Splitting a single purchase across multiple HSA or FSA cards is not currently supported. If one card has insufficient funds, pay with a credit card instead and submit the Flex itemized receipt to your HSA or FSA administrator for reimbursement after purchase.
Test kits ship via standard mail and typically arrive within 3–7 business days. Free shipping is included on all orders — no minimum purchase required. Once your completed sample is mailed back to the lab, processing begins upon receipt at the laboratory.
Yes. PlexusDx customer support is available Monday through Friday, 9am–5pm EST.
Phone: 877-760-2333
Email: support@tests.plexusdx.com
For questions specifically about results, contact results@plexusdx.com. A Registered Dietitian consultation is also available for customers seeking personalized guidance on their test results.
Privacy & Data Security
How we handle, protect, and never misuse your genetic and health data.
Your DNA sample is used solely to generate your genetic reports. Once processing is complete, your physical sample is discarded. Your genetic data is not stored beyond what is required to deliver your results and is never used for research, sold to third parties, or shared with any external organizations without your explicit consent.
No. PlexusDx does not share your genetic data with insurance companies, employers, or any third parties. Your data belongs to you. PlexusDx's privacy practices are designed to ensure your genetic information cannot be used against you in any insurance or employment context.
Yes. PlexusDx uses secure, encrypted storage for all health data. Results are delivered through a password-protected Results Portal accessible only to you. PlexusDx follows applicable data security standards to protect personal health information from unauthorized access, disclosure, or misuse.
You do. Your genetic data belongs to you, not to PlexusDx. It is used exclusively to generate and deliver your reports and is not sold, licensed, or transferred to any third party. You may contact PlexusDx customer support at any time to request deletion of your data.