FAQs

Our Tests

The following questions are specific to PGx and NGx testing.

What is Pharmacogenomics (PGx)?

Pharmacogenomics explores how individual genetic makeup influences drug responses, addressing questions like medication efficacy, understanding drug effects before consumption, and why certain drugs might cause adverse reactions.

Is PGx testing right for me?

Everyone can benefit from the information gleaned from a PGx test. For individuals who are currently taking medications that are ineffective or come with unwelcome reactions, PGx testing can provide data to inform medication decisions and dosing, so you can focus on feeling your best.

Even if you're not currently on any medication, we advise undergoing a PGx test, a one-time requirement. This proves beneficial for future medication needs, allowing you to share your results with your healthcare provider. Tailored treatment based on your DNA ensures personalized care when necessary.

What is an adverse drug reaction (ADR)?

ADR is the term used to describe an unexpected, negative response to medication. There are many different ways to experience an ADR, from mildly uncomfortable side effects to severe complications that could lead to long-term health problems. Research indicates that many ADRs may be preventable with proper precautions.

What medications are covered by the Precision Medication Test?

The Precision Medication Test encompasses over 100+ approved prescription and OTC medications.

View the full list of medications covered by this test.

Why isn't my medication listed in your medication directory?

PlexusDx provides one of the most comprehensive reports in the field. If your medication isn't included, there's insufficient clinical evidence supporting the identification of genetic variants. Our reports incorporate the latest clinical guidance from reputable organizations, including the Clinical Pharmacogenetics Implementation Consortium (CPIC) and the Federal Drug Administration (FDA).

Please note that it is important to consult with your provider before making any changes to your medications. This is a clinical test intended to be shared with your provider.

What is Nutrigenomics (NGx)?

Nutrigenomic (NGx) testing investigates the influence of genetic makeup on nutrient needs. The generic advice to “eat right and exercise” means different things depending on your genetics. This test can help you outline what changes you can make to your daily habits that can impact your weight, energy, and overall health.

Is Nutrigenomics (NGx) right for me?

Everyone can benefit from knowing how your genetics influence your body’s response to nutrition, providing you with a lifetime of guidance.

Orders

Find questions related to ordering.

Does my doctor need to order these tests?

No. You can order the test directly.

Can I order these tests for someone else?

Yes. You can purchase a test for another person. They will need to activate their test kit on our website upon receipt. For minors, parental or guardian consent is required for activation.

Once someone has successfully responded to PGx registration questions, PlexusDx's Clinician Network will order your test for you.

Does my insurance cover these tests?

PlexusDx does not work with health insurance. Navigating insurance for this type of testing can be complex, however we do encourage you to submit a claim to your insurance for reimbursement. While we can't guarantee that your insurance will cover the cost, it doesn't hurt to try.

How long does it take to receive my results?

Once we receive your sample at the lab, it takes approximately 10-14 business days to complete the review and analysis for PGx tests and 2-4 weeks for NGx tests.

Can I use FSA/HSA to cover these tests?

Yes, the cost of each test is typically reimbursable through both Flexible Spending Accounts (FSA) and Health Savings Accounts (HSA).

What is Flex and what is their relationship with PlexusDx?

PlexusDx has partnered with Flex to allow you to use your Health Savings Account (HSA) or Flexible Spending Account (FSA). This means you can now use your HSA or FSA debit card to buy health and wellness tests with pre-tax dollars, resulting in net savings of 30-40%, depending on your tax bracket.

How do I pay with my HSA or FSA card?

To use your HSA or FSA debit card, add products to your cart as usual. At checkout, select "Flex | Pay with HSA/FSA" as your payment option, enter your HSA or FSA debit card, and complete your checkout as usual. If you don't see "Flex | Pay with HSA/FSA," you may be in Shop Pay. Select "checkout as guest" to view more payment options.

What if I don't have my HSA/FSA card available?

If you don't have your HSA or FSA card handy, still select "Flex | Pay with HSA/FSA" as your payment method. Enter your credit card information and Flex will email you an itemized receipt to submit for reimbursement.

Why can't I see Flex as a payment method?

The key here is to make sure you are logged out of Shop Pay. One of the easiest ways to do this is to go through checkout in an incognito window.

Why is my HSA/FSA card being declined?

HSA/FSA cards are debit cards, and the most common reason for declines is insufficient funds. Reach out to your HSA/FSA administrator to confirm your balance.

I submitted my Flex itemized receipt for reimbursement and my FSA requires more information.
Please forward us the request from your FSA, and we will work with the Flex team to issue you a new receipt.
Help! I didn't receive an email from Flex with my itemized receipt and/or letter of medical necessity. What should I do?

Please check your spam folder, as sometimes emails from notifications@withflex.com may be automatically filtered as spam by some email service providers. If you still can't find it, please email support@withflex.com and let them know the email address associated with your order.

I would like to use multiple HSA/FSA cards to pay for an item. Can I do that?

No, unfortunately, this isn't a supported feature right now. If there are insufficient funds in a single HSA or FSA account, you can instead enter a credit card on the Flex checkout page. You will receive an itemized receipt and/or Letter of Medical Necessity from Flex, which you can submit for reimbursement.

Is sales tax covered by HSA/FSA funds, or is it treated separately?

Sales tax for eligible items is also covered by HSA/FSA funds. If the customer has a split cart, the tax will be divided among the cards based on the items.

My HSA/FSA Claim was denied. What should I do?

We strongly recommend checking with your HSA/FSA provider to see if a purchase is eligible prior to completing the purchase. However, if you believe your claim has been wrongly denied, please send over any response from your HSA/FSA provider to us so we can share it with Flex and receive guidance on the next best steps to take. Please note that employer-sponsored FSAs can determine what products are eligible beyond the IRS's guidelines, so it's extremely important to check prior to purchase.

Can a customer purchase a product now and apply for FSA reimbursement in the next calendar year?

The ability to apply for FSA reimbursement in a future calendar year depends on the policy of the specific FSA provider. Most FSA administrators require that the purchase be made during the time of coverage. For example, if the FSA coverage is for 2025, all purchases typically need to be made and/or submitted for reimbursement within that coverage period. However, some administrators may have more flexible rules regarding the timing of when the expense occurred. We recommend that customers review their plan policy to confirm the details. Note: Health Savings Accounts (HSAs) are different and generally allow for reimbursement at any time, even in future years.

Can old (non-Flex) customers use their order confirmation email to apply for HSA/FSA reimbursement?

Unfortunately, for purchases made without using Flex in the checkout to receive an itemized receipt, it may be difficult to apply for reimbursement. For Health Savings Accounts (HSAs), consumers can use an itemized receipt for reimbursement anytime after they have made the purchase, even if it is many years later. For Flexible Spending Accounts (FSAs), most accounts require that the purchase was made in the calendar year during which the consumer had the FSA, as FSAs typically do not roll over. Some FSAs offer a buffer window, allowing customers additional time to submit receipts for expenses incurred during the previous calendar year.

Can I speak to a live person?

Customer Support is available 9am – 5pm EST Monday – Friday.

877-760-2333

support@tests.plexusdx.com

Reporting & Results

Below are common questions about the test results and reports.

What is included in the Precision Medication Test report?

The Precision Medication Test encompasses over 100+ approved prescription and OTC medications.

View the full list of medications covered by this test.

What is covered by the Precision Wellness Test reports?

The PlexusDx Precision Wellness Tests cover over 1000 genetic reports related to your overall health. Here is a small sample...

How you process macronutrients: 

  • Dietary protein
  • Dietary fats
  • Carbohydrates

Choosing the right types of dietary fat:

  • Saturated fat
  • Omega-3
  • Unsaturated fat

Getting enough vitamins:

  • Vitamin B6
  • Vitamin E
  • Vitamin D
  • Vitamin B12
  • Folate
  • Vitamin B2
  • Vitamin C
  • Vitamin A
  • Vitamin K

Getting enough minerals:

  • Zinc
  • Magnesium
  • Iron
  • Potassium
  • Selenium
  • Calcium

Improving your eating habits:

  • Tendency to overeat
  • Sugar cravings
  • Snacking 
What steps should I take after getting my test results?

Receiving your results marks a significant moment in your health journey. They serve as an insightful tool in managing your healthcare effectively. Should you have any inquiries about your results or if you're interested in obtaining clinical advice, please don't hesitate to contact us at results@plexusdx.com.

Additionally, every client who completes our tests has the opportunity to be connected with either a Clinical Pharmacist or Registered Dietitian through the PlexusDx Network upon request.

Does this test provide ancestry information?

This DNA test doesn't offer ancestry details. It focuses solely on how your genes affect your response to specific medications.

Can this test predict my disease risk?

This DNA test isn't designed to assess your likelihood of developing diseases, including cancer.

Privacy

Below are questions about how we are committed to protecting your privacy and information.

How does PlexusDx handle my DNA sample?

Your genetic data is utilized solely for report processing, with no storage or use beyond this requirement. Rest assured, we promptly discard your sample after processing is complete.

Will you share my data with my insurance or employer?

No. Your data is for you, and you only.