




Hormone, Thyroid & Reproductive Health Genetic Test
See how your DNA relates to estrogen, testosterone, thyroid, and reproductive health, for both men and women, and turn those insights into guidance you can act on.
Genetic Tests are a one-time purchase
The Hormone, Thyroid and Reproductive Health Genetic Test turns one cheek swab into 130+ DNA insights across 64 genes, covering estrogen, testosterone, thyroid, fertility, and the reproductive pathways behind them, for both men and women.
What your DNA reveals in this test
Estrogen & progesterone balance
How your genes may relate to the way your body makes, uses, and clears estrogen and progesterone, including the aromatase gene CYP19A1 and COMT. Useful context for the hormone questions you review with your provider.
Testosterone & androgen balance
How your genes may relate to testosterone and the SHBG protein that carries it through your body. These pathways matter for both men and women, not just one.
Fertility & reproductive health
Genes involved in pathways researchers study in relation to fertility and reproductive health, including the FSH and LH hormone receptors. A starting point, not a fertility diagnosis.
Pregnancy & uterine health
How your genes may relate to pregnancy-related pathways and uterine tissue health, including folate metabolism through MTHFR. Helpful background to discuss with your provider.
Cycle & menopause
How your genes may relate to cycle-related symptoms and mood and the menopausal transition, including the estrogen receptor ESR1. Context for the patterns you already notice.
Thyroid function
How your genes may influence thyroid hormone regulation, which connects to energy, mood, and metabolism. Covers TSHR and the DIO2 conversion gene, alongside your sex hormones.
What this test covers
This test analyzes your DNA across the Men's Hormone and Women's Hormone reports: 132 markers across 10 traits, grouped into the six areas below. It covers hormone and reproductive pathways for both men and women.
Estrogen & progesterone balance
How your genes may relate to the way your body makes, uses, and clears estrogen and progesterone. The aromatase gene CYP19A1 and COMT sit here.
Testosterone & androgen balance
How your genes may relate to testosterone and the SHBG protein that carries it through your body. These pathways matter for both men and women.
Fertility & reproductive health
Genes involved in pathways researchers study in relation to fertility and reproductive health, including the FSH and LH hormone receptors.
Pregnancy & uterine health
How your genes may relate to pregnancy-related pathways and uterine tissue health, including folate metabolism through the well-known MTHFR gene.
Cycle & menopause
How your genes may relate to cycle-related symptoms and mood and the menopausal transition, including the estrogen receptor ESR1.
Thyroid function
How your genes may influence thyroid hormone regulation, which connects to energy, mood, and metabolism. Covers TSHR and the DIO2 conversion gene.
You do not have to act on all of it. Pick one or two areas, talk them over with your provider, and build from there. This test is for wellness and education, not diagnosis.
From kit to results in four steps
Order your kit
We ship your DNA collection kit to your door for free, in discreet packaging.
Register and swab at home
Register your kit online with the included instructions, then take a quick, painless cheek swab. No needles, no clinic visit.
Mail it back
Seal your sample in the prepaid return envelope and drop it in the mail. Our CLIA-certified lab analyzes your DNA on the Illumina Global Screening Array.
Get your reports
In about 2 to 4 weeks, your reports and personalized guidance appear in your PlexusDx Results Portal.
Everything included with your test
Two genetic reports
Your Men's Hormone and Women's Hormone reports, delivered together in your PlexusDx Results Portal.
An at-home swab kit
The cheek swab, collection vial, and a prepaid return envelope, with free shipping both ways.
Plain-English insights
Your results in clear language, with discussion points for you and your provider, not raw genetic data.
One swab, 132 markers
A single cheek swab covers all 132 markers across the two reports. Your DNA does not change, so you test once.
The reports inside this test
Each one is a full PlexusDx genetic report. Explore what they cover.
Men's Hormone and Fertility Health Genetic Report
How your genes may relate to testosterone, estrogen, progesterone, fertility, and thyroid pathways, with the SHBG transport gene and reproductive hormone receptors.
View reportWomen's Hormone and Fertility Health Genetic Report
How your genes may relate to estrogen and progesterone balance, androgen levels, fertility, pregnancy, cycle and menopausal pathways, and thyroid regulation.
View reportAll your reports live in one place: your PlexusDx Results Portal, alongside any other PlexusDx tests and reports you own. One login, your whole genetic picture.
PlexusDx tests and reports are for wellness and educational purposes only and are not intended to diagnose, treat, cure, or prevent any disease. Results are delivered through the PlexusDx Results Portal.
One cheek swab unlocks 132 DNA insights across hormones, thyroid, and reproductive health.