Overview
132
genetic insights
2
genetic reports
64
genes
6
focus areas

The Hormone, Thyroid and Reproductive Health Genetic Test turns one cheek swab into 130+ DNA insights across 64 genes, covering estrogen, testosterone, thyroid, fertility, and the reproductive pathways behind them, for both men and women.

Genes in this test
CYP19A1COMTCYP1A1SHBGFAM9BLIN28B
Focus areas
Estrogen & progesterone balanceTestosterone & androgen balanceFertility & reproductive healthPregnancy & uterine healthCycle & menopauseThyroid function
Reports included
Men's Hormone and Fertility Health Genetic ReportWomen's Hormone and Fertility Health Genetic Report
HIPAA-compliant platform
Data never sold
One test for life
What you'll learn

What your DNA reveals in this test

Estrogen & progesterone balance

How your genes may relate to the way your body makes, uses, and clears estrogen and progesterone, including the aromatase gene CYP19A1 and COMT. Useful context for the hormone questions you review with your provider.

Testosterone & androgen balance

How your genes may relate to testosterone and the SHBG protein that carries it through your body. These pathways matter for both men and women, not just one.

Fertility & reproductive health

Genes involved in pathways researchers study in relation to fertility and reproductive health, including the FSH and LH hormone receptors. A starting point, not a fertility diagnosis.

Pregnancy & uterine health

How your genes may relate to pregnancy-related pathways and uterine tissue health, including folate metabolism through MTHFR. Helpful background to discuss with your provider.

Cycle & menopause

How your genes may relate to cycle-related symptoms and mood and the menopausal transition, including the estrogen receptor ESR1. Context for the patterns you already notice.

Thyroid function

How your genes may influence thyroid hormone regulation, which connects to energy, mood, and metabolism. Covers TSHR and the DIO2 conversion gene, alongside your sex hormones.

What this test covers

This test analyzes your DNA across the Men's Hormone and Women's Hormone reports: 132 markers across 10 traits, grouped into the six areas below. It covers hormone and reproductive pathways for both men and women.

Estrogen & progesterone balance

How your genes may relate to the way your body makes, uses, and clears estrogen and progesterone. The aromatase gene CYP19A1 and COMT sit here.

Estrogen metabolismProgesterone balance
Featured genesCYP19A1COMTCYP1A1

Testosterone & androgen balance

How your genes may relate to testosterone and the SHBG protein that carries it through your body. These pathways matter for both men and women.

Testosterone regulationAndrogen balanceHormone transport
Featured genesSHBGFAM9BLIN28B

Fertility & reproductive health

Genes involved in pathways researchers study in relation to fertility and reproductive health, including the FSH and LH hormone receptors.

Fertility-related pathwaysReproductive hormone signaling
Featured genesFSHRLHCGRFSHB

Pregnancy & uterine health

How your genes may relate to pregnancy-related pathways and uterine tissue health, including folate metabolism through the well-known MTHFR gene.

Pregnancy-related pathwaysUterine tissue health
Featured genesMTHFRADIPOQMTHFD1

Cycle & menopause

How your genes may relate to cycle-related symptoms and mood and the menopausal transition, including the estrogen receptor ESR1.

Cycle-related symptomsCycle-related moodMenopausal transition
Featured genesESR1COMTTACR3

Thyroid function

How your genes may influence thyroid hormone regulation, which connects to energy, mood, and metabolism. Covers TSHR and the DIO2 conversion gene.

Thyroid hormone regulation
Featured genesTSHRDIO2THRB

You do not have to act on all of it. Pick one or two areas, talk them over with your provider, and build from there. This test is for wellness and education, not diagnosis.

How it works

From kit to results in four steps

1

Order your kit

We ship your DNA collection kit to your door for free, in discreet packaging.

2

Register and swab at home

Register your kit online with the included instructions, then take a quick, painless cheek swab. No needles, no clinic visit.

3

Mail it back

Seal your sample in the prepaid return envelope and drop it in the mail. Our CLIA-certified lab analyzes your DNA on the Illumina Global Screening Array.

4

Get your reports

In about 2 to 4 weeks, your reports and personalized guidance appear in your PlexusDx Results Portal.

Is this test right for you?
Who it's for
You are starting with your DNA and want one cheek swab to cover hormones, thyroid, and reproductive health in a single kit.
You are a man or a woman who wants to understand how your genes may relate to estrogen, testosterone, and thyroid pathways.
You are curious about fertility, cycle, or menopause-related pathways and want a genetic starting point.
You want personal context to pair with hormone or thyroid blood testing, not generic advice.
You want a DNA foundation to discuss with your provider and to pair with future blood tests and supplements.
What it is not
A diagnostic or fertility test. It does not diagnose, treat, cure, or prevent infertility, thyroid conditions, or any disease.
A measure of your current hormone or thyroid levels. It reflects genetic tendencies only, not blood values.
A substitute for hormone blood work or care from a qualified medical provider.
The right starting point if you already have PlexusDx DNA on file. In that case, add the individual reports from your Results Portal instead.
What you receive

Everything included with your test

Two genetic reports

Your Men's Hormone and Women's Hormone reports, delivered together in your PlexusDx Results Portal.

An at-home swab kit

The cheek swab, collection vial, and a prepaid return envelope, with free shipping both ways.

Plain-English insights

Your results in clear language, with discussion points for you and your provider, not raw genetic data.

One swab, 132 markers

A single cheek swab covers all 132 markers across the two reports. Your DNA does not change, so you test once.

Your ecosystem

The reports inside this test

Each one is a full PlexusDx genetic report. Explore what they cover.

Men's Hormone and Fertility Health Genetic Report

How your genes may relate to testosterone, estrogen, progesterone, fertility, and thyroid pathways, with the SHBG transport gene and reproductive hormone receptors.

View report

Women's Hormone and Fertility Health Genetic Report

How your genes may relate to estrogen and progesterone balance, androgen levels, fertility, pregnancy, cycle and menopausal pathways, and thyroid regulation.

View report

All your reports live in one place: your PlexusDx Results Portal, alongside any other PlexusDx tests and reports you own. One login, your whole genetic picture.

PlexusDx tests and reports are for wellness and educational purposes only and are not intended to diagnose, treat, cure, or prevent any disease. Results are delivered through the PlexusDx Results Portal.

Built on your DNA

One cheek swab unlocks 132 DNA insights across hormones, thyroid, and reproductive health.

$298

Order My Test

Free shipping both ways. One test for life.

Good to know

Frequently asked questions

What is the Hormone, Thyroid and Reproductive Health Genetic Test?

It is an at-home DNA kit that reads 130+ genetic insights across 64 genes tied to estrogen, testosterone, thyroid, fertility, and reproductive health. One cheek swab covers two panels, Men's Hormone and Women's Hormone, for education and long-term wellness, for both men and women.

How does it work, and how long do results take?

Collect a quick cheek swab at home, then mail it back in the prepaid envelope. Your results post to the secure PlexusDx Results Portal in 2 to 4 weeks after the lab receives your sample. Buyers under 18 should register the kit with a parent or guardian.

Is this a diagnostic test?

No. This test is for education and long-term wellness, not diagnosis, treatment, or emergency use. It shows how your genes may relate to hormone, thyroid, and reproductive pathways. Genetics is a guide, not a guarantee, so review your results with a qualified healthcare provider.

Does it cover both men and women?

Yes. This test combines our Men's Hormone and Women's Hormone panels, so it covers estrogen, testosterone, thyroid, fertility, and reproductive pathways for everyone. Some insights are most relevant to one sex, and your reports explain which ones apply to you.

What genes and pathways does this test analyze?

It analyzes 64 genes across estrogen, testosterone, thyroid, fertility, and reproductive pathways. Highlights include SHBG for testosterone transport, CYP19A1 and COMT for estrogen metabolism, FSHR and LHCGR for reproductive hormones, and TSHR, DIO2, and THRB for thyroid function. Every gene is read from your own DNA.