




Food Sensitivity & Allergy Genetic Test
See how your DNA shapes the way you react to foods, allergens, and the nutrients you eat, and turn those insights into personalized guidance you can act on.
Genetic Tests are a one-time purchase
The Food Sensitivity and Allergy Genetic Test turns one cheek swab into 238 DNA insights across 138 genes, covering food and environmental triggers, histamine and intolerance tendencies, and the nutrient chemistry behind them.
What your DNA reveals in this test
Food & drink triggers
How your genes may shape the way you react to gluten, egg, milk, peanut, caffeine, and alcohol, from food sensitivity tendencies to how fast you clear caffeine. A practical starting point for conversations with your provider.
Histamine & intolerance
How well your body breaks histamine down, the chemistry behind food and drink intolerance tendencies. Helpful context for understanding reactions that are not classic allergies.
Environmental & seasonal allergies
How your genes may shape sensitivity to airborne triggers like pollen, grass, mold, and pet dander, including hay-fever-type responses. Useful background for seasonal patterns you may already notice.
Immune & inflammation response
How your genes may shape the immune signaling and inflammation that sit underneath food and skin reactions, including contact responses. Context, not a diagnosis.
Vitamins & minerals
How well your body absorbs and uses key vitamins and minerals like folate, vitamin D, and iron, which shapes how you respond to foods and supplements. The well-known MTHFR gene sits here.
Nutrition & metabolism
How your genes may shape the way you handle fats, carbs, and cholesterol, and which eating patterns may suit you, so food choices can be personal instead of generic.
What this test covers
This test analyzes your DNA across the Allergies & Food Sensitivities and Diet & Nutrition reports: 238 markers across 57 traits, grouped into the six areas below.
Food & drink triggers
How your genes may shape the way you react to common foods and drinks, from gluten, egg, milk, and peanut to caffeine and alcohol. This area includes HLA-DQB1 for peanut response, TLR6 for milk, and CYP1A2 for how fast you clear caffeine.
Histamine & intolerance
How well your body breaks histamine down, the chemistry behind food and drink intolerance tendencies. The histamine enzymes HNMT and AOC1 sit here, along with the HRH1 histamine receptor.
Environmental & seasonal allergies
How your genes may shape sensitivity to airborne triggers like pollen, grass, mold, and pet dander. This area includes IL33 and TSLP for hay-fever-type responses and LRRC32 for grass and mold.
Immune & inflammation response
How your genes may shape immune signaling and inflammation that sit underneath food and skin reactions. This area includes IL6 and IL23R for immune balance and TNF for contact and inflammatory responses.
Vitamins & minerals
How well your body absorbs and uses key vitamins and minerals, which shapes how you respond to foods and supplements. The well-known MTHFR gene sits here for folate, alongside VDR for vitamin D and HFE for iron.
Nutrition & metabolism
How your genes may shape the way you handle fats, carbs, and cholesterol, and which eating patterns may suit you. This area includes FTO for diet response, APOA5 for triglycerides, and FADS1 for fatty acids and cholesterol.
You do not have to act on all of it. Pick one or two areas, talk them over with your doctor, and build from there. This test shows genetic tendencies, not a diagnosis. It does not diagnose allergies and is not for managing severe or life-threatening reactions, so if you have a known allergy keep following your provider's advice and seek emergency care for any severe reaction.
From kit to results in four steps
Order your kit
We ship your DNA collection kit to your door for free, in discreet packaging.
Register and swab at home
Register your kit online with the included instructions, then take a quick, painless cheek swab. No needles, no clinic visit.
Mail it back
Seal your sample in the prepaid return envelope and drop it in the mail. Our CLIA-certified lab analyzes your DNA on the Illumina Global Screening Array.
Get your reports
In about 2 to 4 weeks, your reports and personalized guidance appear in your PlexusDx Results Portal.
Everything included with your test
Two genetic reports
Your Allergies & Food Sensitivities and Diet & Nutrition reports, delivered together in your PlexusDx Results Portal.
An at-home swab kit
The cheek swab, collection vial, and a prepaid return envelope, with free shipping both ways.
Plain-English insights
Your results in clear language, with discussion points for you and your provider, not raw genetic data.
One swab, 238 markers
A single cheek swab covers all 238 markers across the two reports. Your DNA does not change, so you test once.
The reports inside this test
Each one is a full PlexusDx genetic report. Explore what they cover.
Allergies & Food Sensitivities Genetic Report
How your genes may shape reactions to foods, drinks, and environmental triggers, across gluten, egg, milk, peanut, caffeine, histamine, pollen, and pet dander.
View reportDiet & Nutrition Genetic Report
How your genes may shape the way you process vitamins, minerals, fats, and carbs, with diet-type and supplement context to personalize your nutrition.
View reportAll your reports live in one place: your PlexusDx Results Portal, alongside any other PlexusDx tests and reports you own. One login, your whole genetic picture.
PlexusDx tests and reports are for wellness and educational purposes only and are not intended to diagnose, treat, cure, or prevent any disease. Results are delivered through the PlexusDx Results Portal.
One cheek swab unlocks 238 DNA insights across food triggers, allergies, and nutrition.