Overview
129
genetic insights
2
genetic reports
91
genes
6
focus areas

The Cognition and Brain Health Genetic Test turns one cheek swab into 120+ DNA insights across 91 genes, covering focus, memory, and mood plus how your genes shape the way your skin, joints, and senses age over time.

Genes in this test
BDNFCHRNA4KIBRACRHR1ADORA2AMEF2C
Focus areas
Focus, memory & mental clarityMood & emotional balanceBrain chemistry & motivationSkin & visible agingJoints, bones & inflammationSensory, oral & metabolic aging
Reports included
Cognition & Brain Health Genetic ReportHealthy Aging Genetic Report
HIPAA-compliant platform
Data never sold
One test for life
What you'll learn

What your DNA reveals in this test

Focus, memory & mental clarity

How your genes may shape attention, mental speed, and memory, including BDNF for memory and mood. A practical starting point for understanding your everyday cognitive patterns.

Mood & emotional balance

How your genes may shape mood, stress sensitivity, and emotional steadiness, including the stress-hormone receptor CRHR1. Useful context for conversations with your provider.

Brain chemistry & motivation

How your body makes and clears brain chemicals like dopamine, serotonin, and norepinephrine, including the well-known COMT gene. Context for focus, motivation, and reward.

Skin & visible aging

How your genes may shape skin elasticity, fine lines, sun-related skin changes, and hair pigmentation over time, including the pigment gene MC1R. Helpful background for your skincare choices.

Joints, bones & inflammation

How your genes may relate to joint comfort, bone density, tendon resilience, and your everyday inflammatory tendency, including LRP5 for bone. Context to discuss with your provider.

Sensory, oral & metabolic aging

How your genes may relate to hearing and balance, vision and eye health, gum and oral health, and everyday energy as you age. A starting point for prevention where it matters most.

What this test covers

This test analyzes your DNA across the Cognition & Brain Health and Healthy Aging reports: 129 markers across 29 traits, grouped into the six areas below. It covers brain health and the ways your body ages.

Focus, memory & mental clarity

How your genes may shape attention, mental speed, and memory. This area covers focus, learning, and recall, including BDNF for memory and mood and CHRNA4 for attention.

AttentionProcessing speedMemoryCognitive function
Featured genesBDNFCHRNA4KIBRA

Mood & emotional balance

How your genes may shape mood, stress sensitivity, and emotional steadiness, including the stress-hormone receptor CRHR1.

Mood resilienceStress sensitivity
Featured genesCRHR1ADORA2AMEF2C

Brain chemistry & motivation

How your body makes, signals, and clears brain chemicals like dopamine, serotonin, and norepinephrine. The well-known COMT gene sits here, alongside the dopamine and serotonin pathways.

DopamineSerotoninNorepinephrineImpulse control
Featured genesCOMTDRD2SLC6A4

Skin & visible aging

How your genes may shape skin elasticity, fine lines, sun-related skin changes, and hair pigmentation over time, including the well-known pigment gene MC1R and the elastin gene ELN.

Skin aging and elasticityFine lines and wrinklesSun-related skin changesHair pigmentation
Featured genesMC1RELNIRF4

Joints, bones & inflammation

How your genes may relate to joint comfort, bone density, tendon resilience, and your everyday inflammatory tendency, including LRP5 for bone and the vitamin D receptor VDR.

Joint comfortBone densityTendon resilienceInflammatory tendency
Featured genesLRP5VDRCOL11A1

Sensory, oral & metabolic aging

How your genes may relate to hearing and balance, vision and eye health, gum and oral health, and everyday energy as you age, including CFH for vision and KCNE1 for hearing.

Hearing and balanceVision and eye healthGum and oral healthEnergy and fatigue
Featured genesCFHKCNE1ABCG8

You do not have to act on all of it. Pick one or two areas, talk them over with your provider, and focus where it matters most. This test is for wellness and education, not diagnosis.

How it works

From kit to results in four steps

1

Order your kit

We ship your DNA collection kit to your door for free, in discreet packaging.

2

Register and swab at home

Register your kit online with the included instructions, then take a quick, painless cheek swab. No needles, no clinic visit.

3

Mail it back

Seal your sample in the prepaid return envelope and drop it in the mail. Our CLIA-certified lab analyzes your DNA on the Illumina Global Screening Array.

4

Get your reports

In about 2 to 4 weeks, your reports and personalized guidance appear in your PlexusDx Results Portal.

Is this test right for you?
Who it's for
You are starting with your DNA and want one cheek swab to cover brain health and healthy aging in a single kit.
You are curious about how your genes may shape focus, memory, and mood.
You want to understand how your genes relate to the way your skin, joints, and senses age over time.
You want personal lifestyle and supplement context built on your genetics, not generic advice.
You want a DNA foundation to discuss with your provider and to pair with future blood tests and supplements.
What it is not
A diagnostic test. It does not diagnose, treat, cure, or prevent any disease or age-related condition.
A measure of your current health status. It reflects genetic tendencies only, not your present condition.
A substitute for blood work, screening, or care from a qualified medical provider.
The right starting point if you already have PlexusDx DNA on file. In that case, add the individual reports from your Results Portal instead.
What you receive

Everything included with your test

Two genetic reports

Your Cognition & Brain Health and Healthy Aging reports, delivered together in your PlexusDx Results Portal.

An at-home swab kit

The cheek swab, collection vial, and a prepaid return envelope, with free shipping both ways.

Plain-English insights

Your results in clear language, with discussion points for you and your provider, not raw genetic data.

One swab, 129 markers

A single cheek swab covers all 129 markers across the two reports. Your DNA does not change, so you test once.

Your ecosystem

The reports inside this test

Each one is a full PlexusDx genetic report. Explore what they cover.

Cognition & Brain Health Genetic Report

How your genes may shape focus, memory, mood, and brain chemistry, across attention, processing speed, dopamine, serotonin, and emotional balance.

View report

Healthy Aging Genetic Report

How your genes may relate to the way your body ages, across skin and appearance, joints and bones, inflammation, sensory and oral health, and everyday energy.

View report

All your reports live in one place: your PlexusDx Results Portal, alongside any other PlexusDx tests and reports you own. One login, your whole genetic picture.

PlexusDx tests and reports are for wellness and educational purposes only and are not intended to diagnose, treat, cure, or prevent any disease. Results are delivered through the PlexusDx Results Portal.

Built on your DNA

One cheek swab unlocks 129 DNA insights across brain health and healthy aging.

$298

Order My Test

Free shipping both ways. One test for life.

Good to know

Frequently asked questions

What is the Cognition and Brain Health Genetic Test?

It is an at-home DNA kit that reads 120+ genetic insights across 91 genes tied to focus, memory, mood, and how your skin, joints, and senses age. One cheek swab covers two panels, Cognition & Brain Health plus Healthy Aging, for education and long-term wellness.

How does it work, and how long do results take?

Collect a quick cheek swab at home, then mail it back in the prepaid envelope. Your results post to the secure PlexusDx Results Portal in 2 to 4 weeks after the lab receives your sample. Buyers under 18 should register the kit with a parent or guardian.

Is this a diagnostic test?

No. This test is for education and long-term wellness, not diagnosis, treatment, or emergency use. It shows how your genes may relate to brain health and the way your body ages. Genetics is a guide, not a guarantee, so review your results with a qualified healthcare provider.

Do I need to retake this test?

No. Your DNA does not change, so your results stay relevant for life. This is a one-time test. As new research links more genes to brain health and aging, PlexusDx can add insights to your Results Portal without another swab.

What genes and pathways does this test analyze?

It analyzes 91 genes across brain health and healthy-aging pathways. Highlights include BDNF for memory and mood, COMT for dopamine signaling, and KIBRA for memory, plus MC1R for skin and sun response, LRP5 for bone density, and CFH for vision. Every gene is read from your own DNA.