THE BENEFITS

What MIC B12 actually does for you.

WHAT CHANGES

Your metabolism runs on four sparks. We deliver all four.

Methionine, inositol, choline, B12 — four cofactors your body runs methylation on every day. Run low and energy stalls, fat clearance slows, focus blurs. MIC B12 delivers all four through one weekly injection.

WHAT YOU'LL FEEL

Show up to your day differently

Steadier energy through the afternoon. Sharper focus when the day gets long. A body that bounces back instead of dragging.

HOW LONG IT TAKES

Real results take real time

MIC B12 builds week over week. Most people feel steadier energy within two to four weeks. Focus and fat clearance keep compounding through week twelve. Your provider checks in every month and adjusts your plan as you go.

WHY IT WORKS FOR YOU

Built around your biology, not someone else's average

B12 and methylation response varies by genetics — MTHFR, MTR, and others. The optional Precision Peptide Genetic Test analyzes 17 Longevity insights including FOXO3 so your protocol gets shaped around your body.

PEER-REVIEWED RESEARCH

200+

SAM-dependent methylation reactions across human biology — DNA repair, neurotransmitter synthesis, lipid metabolism, and protein function — all rely on methyl donors from the methionine and B12 pathway. Source: Petrossian & Clarke, Communications Biology, 2022.

Compounded medications are not FDA-approved or evaluated for safety, effectiveness, or quality. PlexusDx coordinates care; licensed providers evaluate and prescribe when clinically appropriate; partner pharmacies dispense and label medications.

READY?

Feel the difference your provider designs around you.

Coming Soon

This protocol is launching soon. Check back shortly.

Overview

Compounded MIC B12 is a lipotropic injection prescribed by licensed providers, combining methionine, inositol, choline, and vitamin B12. Provider-determined dosing across 3 commitment tiers. One monthly price covers your provider visit, prescription, medication, and shipping — $129 to $149 per month, all-inclusive, depending on commitment tier. No membership fee. Eligible adults across all 50 states.

  • Weekly subcutaneous injection at provider-determined dosing across 3 commitment tiers
  • Lipotropic mechanism combining methionine, inositol, choline, and vitamin B12 — supports energy metabolism, fat metabolism, and methylation pathways
  • $129 to $149 per month all-inclusive across 3 commitment tiers — covers consult, prescription, compounded medication, shipping
  • Real medical authority — licensed providers in your state, no AI prescriptions
  • 17 Longevity genetic insights including FOXO3 — optional Precision Peptide Genetic Test, $99 as an add-on after your first month

The optional Precision Peptide Genetic Test analyzes 17 Longevity insights including FOXO3 — the most-studied longevity gene, linked to centenarian populations and cellular repair capacity — with crossover into Energy Metabolism, Tissue Repair, and Cognition pathways. Drawn from a 150+ insight panel across 14 pathways. Available for $99 as an add-on after your first month of treatment.

Why trust PlexusDx

Compliance

503A pharmacy-grade medication

Your compounded MIC B12 is prepared by a licensed 503A compounding pharmacy for your prescription — not mass-manufactured.

Coverage

Licensed providers in all 50 states

Available in all 50 states. Five states require a scheduled video consultation — your provider advises.

Privacy

HIPAA-compliant platform

Protected under HIPAA. Never sold or shared without your consent. Results delivered securely through the PlexusDx Results Portal.

Pricing

One transparent price

All-inclusive. Your dose may need to go up. Your price won't.

Telehealth across the US — see state availability below

Pricing

What you pay

Your dose may need to go up. Your price won't.

Starts at $129 /mo

All-inclusive. No membership. Cancel anytime.

Choose your commitment tier

Month-to-month

$149/mo

3-month

$139/mo
Best value

6-month

$129/mo
Async provider intake Rx issuance Compounded MIC B12 Direct shipping

Provider-determined dosing

Your provider reviews your intake and selects your starting protocol — dose and tier guidance. This protocol is currently available in 46 states. We're unable to ship MIC B12 Injection to Arkansas, Indiana, Minnesota, and South Carolina at this time.

WHAT HAPPENS NEXT

After you order

What happens once your intake is in.

Same day

LICENSED REVIEW

Provider review & prescription

A licensed US provider reviews your intake, selects the compound, and writes your prescription.

3–5 business days

503A COMPOUNDING

Pharmacy ships your medication

Your compounded MIC B12 lipotropic ships from a US 503A pharmacy in cold-chain packaging. A 503A pharmacy is a state-licensed compounding facility regulated by FDA and state boards of pharmacy that prepares medications individually for a specific patient based on a valid prescription. Dosing schedule included

Every month

CARE THAT CONTINUES

Ongoing provider care

Unlimited provider messaging, dose adjustments, and clinical check-ins.

Anytime

FLEXIBILITY

Cancel anytime, no fees

Cancel anytime — no fees, no contracts. Your provider reviews each refill.

OUR COMMITMENT

Nothing is charged until your provider approves your prescription. Cancel anytime, no fees.

EVERYTHING INCLUDED

What's included

Your provider, your pharmacy, your direct-to-door shipping — everything in your monthly MIC B12 Protocol protocol.

PROVIDER

Licensed, async

Licensed providers in all 50 states. Most patients reviewed within one business day.

PHARMACY

503A compounded

Pharmacy-grade Methionine + Inositol + Choline + B12 prepared for your prescription.

SHIPPING

Direct-to-door

Cold-chain packed. Ships from U.S. partner pharmacy.

ALL-INCLUSIVE

One all-inclusive price

Provider, prescription, medication, and shipping — in one monthly charge. No membership.

WHAT YOU WON'T PAY
Membership fee
Consult charge
Hidden fees
REFILLS

Provider-reviewed

Each refill re-authorized by your provider. Not auto-shipped.

MONITORING

Monthly check-ins

Provider check-ins to assess response and adjust formulation as needed.

FLEXIBILITY

Cancel anytime

No long-term contract. Pause or stop between refills.

Optional add-on
Available post-enrollment

The optional Precision Peptide Genetic Test analyzes 17 Longevity insights including FOXO3 — the most-studied longevity gene, linked to centenarian populations and cellular repair capacity — drawn from a 150+ insight panel across 14 pathways. Available for $99 as an add-on after your first month of treatment.

17
Pathway insights
150+
Total panel
14
Pathways
$99
Add-on
Featured SNP
FOXO3
the most-studied longevity gene, linked to centenarian populations and cellular repair capacity

CLINICAL FIT CHECK

Is this protocol right for you?

We lead with safety considerations first. If any exclusion applies to you, stop here and speak with your primary care provider before starting intake.

SAFETY EXCLUSIONS

Skip this protocol if…

MALIGNANCY HISTORY

Active malignancy or recent cancer diagnosis

PREGNANCY STATUS

Pregnancy or breastfeeding

ORGAN DISEASE

Severe hepatic or renal impairment

SAFETY

Hypersensitivity to B12, methionine, or excipients

ELIGIBLE

You're a fit if…

ENERGY & METABOLISM

Adults seeking energy, methylation, or metabolic support

CLINICAL OVERSIGHT

Want licensed provider oversight across all 50 states

PRICING TRANSPARENCY

Want one all-inclusive price with no hidden fees

DATA-GUIDED CARE

You prefer clinical decisions informed by your personal health data

PROVIDER VERDICT

Your licensed provider confirms final eligibility during intake review. No medication ships without their sign-off.

Built differently

What makes PlexusDx different

Five things every shopper deserves before they sign up.

THE DIFFERENTIATOR

Genetics-informed care from a complete precision health platform

17 Longevity insights via the Precision Peptide Genetic Test — across 14 pathways, 49 peptides. The only telehealth peptide protocol with a genetic testing layer.

TRANSPARENCY

Radically transparent

Every dose level and every price published.

PRICING

All-inclusive

One price for intake, Rx, medication, shipping.

CLINICAL

Async clinical oversight

No in-person visits. Available in all 50 states.

NO GATE

No membership gate

Your first dollar goes toward care, not a subscription.

Clinical details

Clinical details

How this compound works and what lab work is involved.

Compound spec

Class

Lipotropic cofactor

Methionine + inositol + choline + B12


Route

Subcutaneous injection

Self-administered weekly


Half-life

Provider-set

weekly cadence per provider


Compounded by

503A pharmacy

licensed US partner

How it works

About this compound

MIC B12 is a lipotropic injection combining four active cofactors — methionine, inositol, choline, and vitamin B12 — that support fat metabolism, methylation, energy production, and liver function.

Your provider determines your MIC B12 dose and weekly cadence during intake review. Pricing is structured in three commitment tiers from $129 to $149 per month, all delivered via subcutaneous injection under clinical supervision.

See how PlexusDx customers describe their precision health journey — read Customer Stories.

Why it matters

Aging response varies by genetics. The optional Precision Peptide Genetic Test analyzes 17 Longevity insights including FOXO3 — the most-studied longevity gene, linked to centenarian populations and cellular repair capacity. Available for $99 as an add-on after your first month of treatment.

Lab requirements
No blood work required at intake. Blood testing is available at patient election and may be recommended by your provider based on your individual health history. At-home blood collection is available through Red Drop Dx — no clinic visit required.
NOT REQUIRED
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MIC B12 Protocol — FAQ

Answers before you start

Straight answers on pricing, formulation, and what's included — pulled from the questions Longevity patients ask most.

PRICING

What does my monthly price include?

MIC B12 is priced by commitment tier — month-to-month $149, 3-month $139, and 6-month $129 (best value). All three tiers include async provider consultation, prescription, compounded MIC B12 lipotropic injection, supplies, and cold-chain shipping. No membership fee, no hidden charges.

INCLUSIONS

What arrives in my monthly package?

Every monthly charge includes async provider consultation and intake review, your prescription written by a licensed provider in your state, compounded MIC B12 lipotropic vials (Methionine, Inositol, Choline, B12), syringes, alcohol swabs, and cold-chain shipping in all 50 states. Refills are provider-reviewed and authorized through your portal — no separate re-intake required unless your tier changes.

FORMULATION

Why does the price change across commitment tiers?

MIC B12 is offered in four commitment tiers — month-to-month at $149, 3-month at $139, 6-month at $129, and 12-month at $124. Longer commitments lock a lower per-month price; the formulation, dose, and supply you receive are identical across all four tiers. Your provider determines your dosing cadence, not your tier.

MECHANISM

What is MIC B12 and how does it support longevity?

MIC B12 is a lipotropic injection combining four active cofactors — Methionine, Inositol, Choline, and B12 — central to methylation, lipid metabolism, and cellular energy production. These cofactors support methylation pathway function, hepatic lipid processing, and mitochondrial energy output — mechanisms that influence metabolism, energy, and long-term cellular resilience. MIC B12 is intended to support these pathways rather than treat any specific deficiency — a supporting mechanism in clinical longevity protocols.

GENETICS

Do I need my Precision Peptide Genetic Test before starting?

No — the Precision Peptide Genetic Test is optional and available as a $99 add-on after your first month of treatment. Your provider can prescribe MIC B12 based on standard intake without genetic data. The test analyzes 14 pathways, 49 peptides, and 150+ genetic insights — including 17 Longevity-Aging insights with FOXO3 — providing additional context that may inform long-term protocol adjustments.

FLEXIBILITY

What if I need a different tier or compound?

Tier upgrades adjust your billing automatically. If your provider recommends a different longevity compound (NAD+, Sermorelin, or others), they can switch your prescription and your billing updates to reflect the new compound. You can pause or cancel anytime from your account — no fees, no long-term contract. No fees to switch.

─── READY TO START

Start your MIC B12 protocol today

Three reasons to start your longevity protocol with PlexusDx.

ENROLL TODAY
Ready to start your MIC B12 protocol?

Order your MIC B12 protocol today. Gain access to 17 Longevity-Aging genetic insights post-enrollment, including FOXO3. Make informed decisions supported by clinical oversight and your unique biology.

Coming Soon
~60 second intake · $0 until Rx approved
TRANSPARENCY
Every formulation, every price
Published before you enroll. No intake required to see prices.
Radically transparent
ALL-INCLUSIVE
One price, all-in
Intake, Rx, medication, and shipping — one monthly price.
No surprise billing
GENETICS-INFORMED
Your biology, your care
150+ insights across 14 pathways, available post-enrollment for $99.
The only telehealth layer
Important Information
Compounded medications are not approved by the FDA or reviewed for quality, safety, or efficacy.

Novo Nordisk, Inc. is the only United States company with FDA-approved products containing semaglutide, identified under the trade names Rybelsus®, Ozempic®, and Wegovy®.

Lilly USA LLC is the only United States company with FDA-approved products containing tirzepatide, identified under the trade names Zepbound® and Mounjaro®.

The Precision Peptide Genetic Test analyzes how your genes influence peptide-related biological pathways. It does not recommend, prescribe, or determine which peptides you should use. Consult a qualified healthcare provider before beginning any peptide protocol.