Longevity Protocols

Seven prescription longevity protocols. Four ways to start.

Seven compounded longevity protocols, built around your genetics.

Starts at $59/mo 12-month plan

Use code GETSTARTED for 10% off your first order. New patients, first order only.

Does not apply to genetic tests, blood tests, or supplements.

Active adult outdoors representing PlexusDx longevity protocols for healthy aging

7 PROTOCOLS

7 compounds

ACROSS THE U.S.

Licensed providers

NO MEMBERSHIP FEE

Cancel future renewals anytime

GENETICS

17 insights · $99 add-on

Overview

Overview of PlexusDx Longevity Protocols.

PlexusDx Longevity Protocols offer seven prescription compounds — NAD+, Sermorelin, Glutathione, MIC + B12, Lipo C, GHK-Cu Rx, and PT-141 — so the protocol works for your body, your goals, and how you want to feel about your progress.

  • 7 prescription longevity protocols
  • 1-, 3-, 6- or 12-month plans, with no membership fee
  • Licensed providers across the U.S., no clinic visit required
  • Real medical authority — licensed providers in your state, no AI prescriptions
  • 17 Longevity genetic insights via optional GLP-1 & Peptide Pathways Genetic Test

The optional GLP-1 & Peptide Pathways Genetic Test analyzes 17 Longevity insights including FOXO3 — a longevity gene linked to living past 100 — with crossover into Energy Metabolism, Tissue Repair, and Cognition pathways. Drawn from a 150+ insight panel across 14 pathways. Available for $99 as an add-on after your first month of treatment.

What do you want to work on first?

Choose a 1-, 3-, 6- or 12-month plan. 3-, 6- and 12-month plans are charged once, up front, and renew automatically until you cancel future renewals.

  • HSA and FSA cards accepted at checkout
  • Pay over time on 3-, 6- and 12-month plans
  • No membership fee
  • Shipping included

Your provider decides whether a medication is right for you.

Choose your longevity compound

Seven compounded longevity protocols across four online visits. Your price depends on your plan length.

Energy and cellular health

MIC + B12

Methionine, inositol, choline and B12. Injection.

Starts at $69/mo12-month plan

$828 billed up front · $99 month to month

Lipo C

Lipotropics plus L-carnitine. Injection.

Starts at $109/mo12-month plan

$1,308 billed up front · $139 month to month

Sleep and recovery

Sermorelin

Asks your body to make more of its own growth hormone. Injection.

Starts at $119/mo12-month plan

$1,428 billed up front · $159 month to month

Skin

GHK-Cu

Copper peptide cream, 0.2%, 0.5% or 2%.

Starts at $59/mo12-month plan

From $708 billed up front · from $89 month to month

Sexual health

Trending

PT-141

Melanocortin receptor agonist. Injection.

Starts at $159/mo12-month plan

$1,908 billed up front · $189 month to month

Understand your options

Compare your longevity options

Each protocol, plain English: how it works, who it's for.

NAD+Most prescribedCellular energy

BasicsYour cells run on NAD+. Prescription injection.

Made forPeople focused on energy and mental clarity.

SermorelinSleep + recovery

BasicsYour body already makes growth hormone. Sermorelin asks it to make more.

Made forPeople focused on sleep and recovery.

GlutathioneAntioxidant defense

BasicsYour body's master antioxidant. Prescription injection.

Made forPeople focused on energy and recovery.

MIC + B12Energy and cellular health

BasicsYour metabolism runs on four sparks. One shot, all four.

Made forPeople focused on energy and metabolism.

Lipo CEnergy and cellular health

BasicsLipotropics plus L-carnitine. One shot.

Made forPeople focused on metabolism and recovery.

GHK-CuSkin + tissue repair

BasicsCopper peptide cream, 0.2%, 0.5% or 2%.

Made forPeople focused on skin firmness and texture.

PT-141Desire + arousal

BasicsMelanocortin receptor agonist. Injection.

Made forWomen and men focused on desire and arousal.

Every protocol is prescribed by a licensed provider.

Longevity Genetic Pathway

Add 17 Longevity genetic insights.

Before you start — or alongside your protocol — the GLP-1 & Peptide Pathways Genetic Test analyzes 17 Longevity insights drawn from a 150+ insight panel across 14 pathways.

Includes FOXO3 rs2802292, a longevity gene linked to living past 100.

Available for $99 as an add-on after your first month of treatment.

Learn About the Genetic Test →

Optional · Not required to start your protocol

What happens next

After you order

Your provider, your pharmacy, your ongoing care — what happens after your online visit.

PlexusDx Longevity Protocols provider review
1
Online visit

Licensed review

Provider review & prescription

A licensed U.S. provider reviews your online visit.

PlexusDx Longevity Protocols pharmacy shipping
2
Ships to your door

503A compounding

Pharmacy ships your medication

Your compounded medication ships from a US 503A pharmacy in discreet packaging.

PlexusDx Longevity Protocols ongoing care
3
Ongoing

Care that continues

Ongoing provider care

Your provider adjusts your plan as you go. Cancel future renewals anytime.

When you’re charged

Cards are charged once your prescription is sent to the pharmacy.

Eligibility & exclusions

Who these protocols are for

Clinical eligibility signals and exclusion criteria. Final eligibility is confirmed by your licensed provider during intake.

Eligible patients

Who qualifies

Adult eligibility

Adults 18+ pursuing energy, recovery, cognition, or vitality.

Medications for four goals: energy, sleep and recovery, skin, and sexual health. No one-size-fits-all stack.

Dual motivation

You want to feel better and look the part.

Longevity protocols sit at the intersection of clinical credibility and the vitality you see in the mirror. Both motivations are honored — neither is moralized.

Provider-led care

A licensed provider reviews your online visit — not an algorithm.

You stay in the loop; you don't manage your own dosing.

Data-guided option

Curious what your longevity genes say.

The optional GLP-1 & Peptide Pathways Genetic Test analyzes 17 Longevity insights including FOXO3 — a longevity gene linked to living past 100 — from a 150+ insight panel across 14 pathways. $99 add-on after your first month.

Exclusion criteria

Not a fit if

Pregnancy or breastfeeding

Currently pregnant, breastfeeding or planning a pregnancy.

Longevity protocols are not appropriate during these life stages.

Uncontrolled cardiovascular conditions

Uncontrolled hypertension or recent cardiovascular event (PT-141).

Compound-specific exclusions apply. Your provider reviews your answers before prescribing.

Concurrent medication conflicts

Certain prescribed medications conflict with specific compounds.

The intake captures your current medication list; your provider reviews for interactions before prescribing.

Hypersensitivity to compound actives

Known allergies to any active across the seven compounds.

Actives include NAD+, copper peptides, glutathione, and bremelanotide. Disclose during intake; your provider screens and adjusts accordingly.

Included in every plan

What's included in every PlexusDx Longevity protocol

Your plan price covers your online visit, prescription, medication and shipping.

Provider consultation & medical review

Included

Prescription & ongoing dose titration

Your provider writes the prescription and adjusts your dose over time as needed.

Included

Compounded medication from a 503A pharmacy

Your medication is prepared by a US-licensed 503A compounding pharmacy specifically for your prescription — not mass-manufactured.

Included

Discreet shipping to your door

Medication ships from the pharmacy in discreet packaging.

Included

Patient portal

Pause a delivery or update your shipping address in your patient portal at my.plexusdx.com.

Included

Published prices

No membership fee. Every plan price is published on each product page.

Frequently Asked

Answers before you enroll

Pricing, eligibility, genetics, compounding, and what happens after you start — directly answered, no hedging.

Pricing

How much do Longevity protocols cost, and what's included?

On a 12-month plan, prices start at $59/mo for GHK-Cu 0.2% cream ($708 billed up front), $69/mo for glutathione and MIC + B12, $109/mo for Lipo C, $119/mo for NAD+ and sermorelin, and $159/mo for PT-141. On a 1-month plan, they run $89 to $189. Your plan price covers your online visit, prescription, medication and shipping, with no membership fee.

Coverage

Are Longevity protocols available in my state?

Longevity protocols are prescribed by licensed providers across the U.S. Your provider confirms availability in your state at your visit.

Genetic Testing

Do I have to take the genetic test to enroll?

No. The GLP-1 & Peptide Pathways Genetic Test is optional and available for $99 as an add-on after your first month of treatment. It analyzes 17 Longevity insights including FOXO3 — a longevity gene linked to living past 100 — drawn from a 150+ insight panel across 14 pathways. Your provider can prescribe without it.

Online visits

Which online visit should I start?

Start with the area you want to work on first. For energy and cellular health, start the Longevity visit; for sleep and recovery, the Sermorelin visit; for skin, the GHK-Cu visit; for sexual health, the PT-141 visit. A licensed provider reviews each visit and decides whether a medication is right for you.

Form Factors

Do I have to inject? What are the alternatives?

Most longevity medications are injections. The exception is GHK-Cu, a copper peptide cream in 0.2%, 0.5% or 2% strengths, with no needles.

Online visit

What does the online visit involve?

A short online visit about your goals, health history and current medications. No clinic visit is needed.

Safety

Who shouldn't take Longevity protocols?

Anyone who is pregnant, breastfeeding or planning a pregnancy, and anyone with active cancer, severe liver or kidney disease, or a known allergy to an ingredient in the medication. PT-141 also excludes uncontrolled hypertension and a recent cardiovascular event. Every online visit asks about your health history, medications and allergies; the Longevity visit ends for G6PD deficiency, chronic kidney disease, liver cirrhosis or current cancer treatment. Your provider reviews your answers before prescribing.

Billing

How does billing work? Can I cancel?

Choose a 1-, 3-, 6- or 12-month plan. 3-, 6- and 12-month plans are charged once, up front, and renew automatically until you cancel future renewals. Each plan renews for the same term at your existing price. HSA and FSA cards accepted at checkout. Pay over time on 3-, 6- and 12-month plans. Cancel future renewals anytime. Canceling does not create a prorated refund of a prepaid plan.