THE BENEFITS

What PT-141 actually does for you.

WHAT CHANGES

Desire and arousal that respond to your biology

PT-141 acts on melanocortin receptors in the central nervous system — a different pathway than blood-flow medications. Low desire often isn't physical — it's a quiet signal in the brain. PT-141 targets the brain's desire and arousal circuits directly, so the change feels physiological, not pharmaceutical.

WHAT YOU'LL FEEL

Show up to your day differently

Confidence that builds across weeks. Anticipation that returns. A relationship to intimacy that feels less negotiated and more natural.

HOW LONG IT TAKES

Real results take real time

PT-141 acts on-demand per dose. Finding your right cadence and dose takes a few weeks of provider-supervised calibration. Most people settle into a steady rhythm by week four to six. Your provider checks in every month and adjusts your plan as you go.

WHY IT WORKS FOR YOU

Built around your biology, not someone else's average

Sexual response varies by genetics. The optional Precision Peptide Genetic Test analyzes 6 Sexual Health insights including eNOS so your protocol gets shaped around your body.

PEER-REVIEWED RESEARCH

MC4R

PT-141 (Bremelanotide) is a melanocortin-4 receptor (MC4R) agonist that acts on central nervous system pathways governing sexual desire and arousal — distinct from peripheral blood-flow mechanisms. Source: Pfaus et al., Annals of the New York Academy of Sciences, 2007.

Compounded medications are not FDA-approved or evaluated for safety, effectiveness, or quality. PlexusDx coordinates care; licensed providers evaluate and prescribe when clinically appropriate; partner pharmacies dispense and label medications.

READY?

Feel the difference your provider designs around you.

Coming Soon

This protocol is launching soon. Check back shortly.

Overview

Compounded PT-141 (Bremelanotide) is a melanocortin receptor agonist prescribed by licensed providers as a pharmacy-grade injection. Provider-determined dosing cadence. One monthly price covers your provider visit, prescription, medication, and shipping — $219 per month flat, no commitment tiers. No membership fee. Eligible adults in all 50 states.

  • Provider-determined injection dosing — on-demand cadence per provider guidance
  • PT-141 mechanism — melanocortin-4 receptor (MC4R) agonist acting on central nervous system pathways for sexual desire and arousal
  • $219 per month flat all-inclusive — covers consult, prescription, compounded medication, shipping
  • Real medical authority — licensed providers in your state, no AI prescriptions
  • 6 Sexual Health genetic insights including eNOS — optional Precision Peptide Genetic Test, $99 as an add-on after your first month

The optional Precision Peptide Genetic Test analyzes 6 Sexual Health insights including eNOS (NOS3) — a nitric-oxide synthase variant that influences endothelial function and PDE5-pathway response — with crossover into Mood and Reproductive Health pathways. Drawn from a 150+ insight panel across 14 pathways. Available for $99 as an add-on after your first month of treatment.

Why trust PlexusDx

Compliance

503A pharmacy-grade medication

Your compounded PT-141 is prepared by a licensed 503A compounding pharmacy for your prescription — not mass-manufactured.

Coverage

Licensed providers in all 50 states

Available in all 50 states. Five states require a scheduled video consultation — your provider advises.

Privacy

HIPAA-compliant platform

Protected under HIPAA. Never sold or shared without your consent. Results delivered securely through the PlexusDx Results Portal.

Pricing

One transparent price

All-inclusive. Your dose may need to go up. Your price won't.

Telehealth across the US — see state availability below

Pricing

What you pay

$219 /mo

All-inclusive. No membership. Cancel anytime.

Async provider intake Rx issuance Compounded PT-141 Direct shipping

Provider-determined dosing

Your provider reviews your intake and selects your starting protocol — dose and cadence guidance. Available in all 50 states. Five states require a scheduled live consultation rather than async intake.

WHAT HAPPENS NEXT

After you order

What happens once your intake is in.

Same day

LICENSED REVIEW

Provider review & prescription

A licensed US provider reviews your intake, selects the compound, and writes your prescription.

3–5 business days

503A COMPOUNDING

Pharmacy ships your medication

Your compounded PT-141 ships from a US 503A pharmacy in your provider-selected formulation. A 503A pharmacy is a state-licensed compounding facility regulated by FDA and state boards of pharmacy that prepares medications individually for a specific patient based on a valid prescription. Dosing instructions included.

Every month

CARE THAT CONTINUES

Ongoing provider care

Unlimited provider messaging, dose adjustments, and clinical check-ins.

Anytime

FLEXIBILITY

Cancel anytime, no fees

Cancel anytime — no fees, no contracts. Your provider reviews each refill.

OUR COMMITMENT

Nothing is charged until your provider approves your prescription. Cancel anytime, no fees.

EVERYTHING INCLUDED

What's included

Your provider, your pharmacy, your direct-to-door shipping — everything in your monthly PT-141 protocol.

PROVIDER

Licensed, async

Licensed providers in all 50 states. Most patients reviewed within one business day.

PHARMACY

503A compounded

Pharmacy-grade PT-141 prepared for your provider-selected formulation.

SHIPPING

Direct-to-door

Discreet packaging. Ships from U.S. partner pharmacy.

ALL-INCLUSIVE

One all-inclusive price

Provider, prescription, medication, and shipping — in one monthly charge. No membership.

WHAT YOU WON'T PAY
Membership fee
Consult charge
Hidden fees
REFILLS

Provider-reviewed

Each refill re-authorized by your provider. Not auto-shipped.

MONITORING

Monthly check-ins

Provider check-ins to assess response and adjust formulation as needed.

FLEXIBILITY

Cancel anytime

No long-term contract. Pause or stop between refills.

Optional add-on
Available post-enrollment

The optional Precision Peptide Genetic Test analyzes 6 Sexual Health insights including eNOS (NOS3) — a nitric-oxide synthase variant that influences endothelial function and pde5-pathway response — drawn from a 150+ insight panel across 14 pathways. Available for $99 as an add-on after your first month of treatment.

6
Pathway insights
150+
Total panel
14
Pathways
$99
Add-on
Featured SNP
eNOS (NOS3)
a nitric-oxide synthase variant that influences endothelial function and PDE5-pathway response

CLINICAL FIT CHECK

Is this protocol right for you?

We lead with safety considerations first. If any exclusion applies to you, stop here and speak with your primary care provider before starting intake.

SAFETY EXCLUSIONS

Skip this protocol if…

MALIGNANCY HISTORY

Active or recent cancer diagnosis

PREGNANCY STATUS

Pregnant, breastfeeding, or planning pregnancy

ORGAN DISEASE

Severe hepatic, renal, or cardiovascular disease (including uncontrolled hypertension)

KNOWN ALLERGY

Hypersensitivity to PT-141 (Bremelanotide) or compounded ingredients

ELIGIBLE

You're a fit if…

AGE & SYMPTOMS

Adults seeking provider-supervised support for sexual desire and arousal

CLINICAL OVERSIGHT

Want licensed provider oversight across all 50 states

PRICING TRANSPARENCY

Want one all-inclusive price with no hidden fees

DATA-GUIDED CARE

You prefer clinical decisions informed by your personal health data

PROVIDER VERDICT

Your licensed provider confirms final eligibility during intake review. No medication ships without their sign-off.

Built differently

What makes PlexusDx different

Five things every shopper deserves before they sign up.

THE DIFFERENTIATOR

Genetics-informed care from a complete precision health platform

6 Sexual Health insights via the Precision Peptide Genetic Test — across 14 pathways, 49 peptides. The only telehealth peptide protocol with a genetic testing layer.

TRANSPARENCY

Radically transparent

Every dose level and every price published.

PRICING

All-inclusive

One price for intake, Rx, medication, shipping.

CLINICAL

Async clinical oversight

No in-person visits. Available in all 50 states.

NO GATE

No membership gate

Your first dollar goes toward care, not a subscription.

Clinical details

Clinical details

How this compound works and what lab work is involved.

Compound spec

Class

Melanocortin agonist

MC4R-targeting peptide


Route

Injection

subcutaneous


Half-life

On-demand

minutes-to-onset, hours-of-effect


Compounded by

503A pharmacy

licensed US partner

How it works

About this compound

PT-141 (Bremelanotide) is a melanocortin receptor agonist that acts primarily on the melanocortin-4 receptor (MC4R) in the central nervous system. Unlike peripheral blood-flow medications, PT-141 targets the brain pathways governing sexual desire and arousal directly, producing effects that originate centrally rather than vascularly.

Your provider determines your PT-141 dose and on-demand cadence during intake review. PT-141 is delivered as a compounded subcutaneous injection at $219 per month flat, all clinically supervised.

See how PlexusDx customers describe their precision health journey — read Customer Stories.

Why it matters

Sexual response varies by genetics. The optional Precision Peptide Genetic Test analyzes 6 Sexual Health insights including eNOS (NOS3) — a nitric-oxide synthase variant that influences endothelial function and PDE5-pathway response. Available for $99 as an add-on after your first month of treatment.

Lab requirements
No blood work required at intake. Blood testing is available at patient election and may be recommended by your provider based on your individual health history. At-home blood collection is available through Red Drop Dx — no clinic visit required.
NOT REQUIRED
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PT-141 — FAQ

Answers before you start

Straight answers on pricing, dosing, and what's included — pulled from the questions sexual health patients ask most.

PRICING

How does PT-141 pricing work?

PT-141 is priced at a single flat monthly rate of $219/mo, all-inclusive. This covers async provider consultation, prescription, compounded PT-141 medication, and shipping — no membership fee, no commitment tiers, no per-dose surcharge.

INCLUSIONS

What's included in every monthly charge?

Every monthly charge includes async provider consultation and intake review, your prescription written by a licensed provider in your state, compounded PT-141 medication, and free discreet shipping in all 50 states. Refills are provider-reviewed and authorized through your portal — no separate re-intake required unless your protocol changes.

DOSING

How does on-demand cadence work?

PT-141 is dosed on-demand — typically 30 to 60 minutes before anticipated activity. Onset is measured in minutes; effect duration is measured in hours. Your provider determines your specific dose and recommended cadence during intake review based on your clinical profile and response. Effects are not cumulative — each dose is independent.

MECHANISM

What is PT-141 and how does it work?

PT-141 (Bremelanotide) is a melanocortin receptor agonist that acts primarily on the melanocortin-4 receptor (MC4R) in the central nervous system. Unlike peripheral blood-flow medications, PT-141 targets the brain pathways governing sexual desire and arousal directly — effects originate centrally rather than vascularly.

GENETICS

Do I need my Precision Peptide Genetic Test before starting?

No — the Precision Peptide Genetic Test is optional and available as a $99 add-on after your first month of treatment. Your provider can prescribe PT-141 based on standard intake without genetic data. The test analyzes 14 pathways, 49 peptides, and 150+ genetic insights — including 6 Sexual Health insights with eNOS (NOS3) — providing additional context that may inform your protocol over time.

FLEXIBILITY

What if I want to pause or switch compounds?

You can pause, cancel, or switch protocols at any time with provider approval — no fees, no contracts. If your provider determines a different compound is a better clinical fit, they'll initiate the switch and billing adjusts automatically. No early-termination fees.

─── READY TO START

Start your PT-141 protocol today

Three reasons to start your sexual health protocol with PlexusDx.

ENROLL TODAY
Ready to start your PT-141 protocol?

Order your PT-141 protocol today. Gain access to 6 Sexual Health genetic insights post-enrollment, including eNOS (NOS3). Make informed decisions supported by clinical oversight and your unique biology.

Coming Soon
~60 second intake · $0 until Rx approved
TRANSPARENCY
Every dose, every price
Published before you enroll. No intake required to see prices.
Radically transparent
ALL-INCLUSIVE
One price, all-in
Intake, Rx, medication, and shipping — one monthly price.
No surprise billing
GENETICS-INFORMED
Your biology, your care
6 Sexual Health insights including eNOS, available post-enrollment for $99.
The only telehealth layer
Important Information
Compounded medications are not approved by the FDA or reviewed for quality, safety, or efficacy.

Novo Nordisk, Inc. is the only United States company with FDA-approved products containing semaglutide, identified under the trade names Rybelsus®, Ozempic®, and Wegovy®.

Lilly USA LLC is the only United States company with FDA-approved products containing tirzepatide, identified under the trade names Zepbound® and Mounjaro®.

The Precision Peptide Genetic Test analyzes how your genes influence peptide-related biological pathways. It does not recommend, prescribe, or determine which peptides you should use. Consult a qualified healthcare provider before beginning any peptide protocol.