Overview
36
genetic insights
7
traits
26
genes
5
focus areas

The Longevity & Lifespan Genetic Report turns your existing PlexusDx DNA into 36+ insights across 26 genes, covering cellular aging, NAD+ and cellular energy, telomere maintenance, heart and cardiovascular health, and cholesterol and lipids.

Genes in this report
FOXO3IGF1RTP53SIRT1SIRT6SIRT3
Focus areas
Cellular aging & longevityNAD+ & cellular energyTelomeres & cellular maintenanceHeart & cardiovascular healthCholesterol & lipids

For wellness and educational use only. Not intended to diagnose, treat, cure, or prevent disease.

HIPAA-compliant platform
Data never sold
One test for life

What you'll learn

Cellular aging and longevity

See how longevity-linked genes like FOXO3 and IGF1R relate to the pathways researchers study in healthy aging.

NAD and cellular energy

Learn how sirtuin genes such as SIRT1 and SIRT6 relate to how your cells produce and manage energy.

Telomere maintenance

Understand how genes like TERT and KL (Klotho) relate to telomeres and long-term cellular upkeep.

Heart and cardiovascular health

See how genes such as PCSK9, LDLR, and ACE relate to the health of your heart and blood vessels.

Cholesterol and lipids

Find out how genes like CETP and ABCA1 relate to how your body handles cholesterol and fats.

What to do with your results

Get plain-language explanations and practical points to bring to your provider. Your DNA does not change, so this is one test for life.

For an educational overview, see our learning resources

What your report covers

Your Longevity and Lifespan report looks at 36 genetic insights across 26 genes, grouped into five plain-language areas of healthy aging. Each one shows how your genes relate to a pathway, not a diagnosis.

Cellular aging & longevity

These genes are studied for how they relate to cellular aging and the pathways linked with a longer, healthier life.

Longevity and healthy aging
Featured genesFOXO3IGF1RTP53

NAD+ & cellular energy

These genes are involved in NAD and the sirtuin pathways your cells use to make and manage energy.

NAD and sirtuin activity
Featured genesSIRT1SIRT6SIRT3

Telomeres & cellular maintenance

These genes relate to telomeres, the protective caps on your DNA, and how your cells maintain themselves over time.

Telomere maintenanceCellular upkeep
Featured genesTERTKLHSPA1L

Heart & cardiovascular health

These genes are studied for how they relate to the health of your heart and blood vessels as you age.

Heart and vessel health
Featured genesPCSK9LDLRACE

Cholesterol & lipids

These genes relate to how your body handles cholesterol and other fats in your blood.

Cholesterol and lipid handling
Featured genesCETPABCA1APOB

These insights describe tendencies your genes are associated with, not certainties about your health or how long you will live. They are a starting point for conversations with your provider.

How it works

1
A plain-language summary of what the finding means.
2
The genetic variants and pathway context behind it.
3
Practical lifestyle and discussion points for you and your provider.
4
Clear framing that insights show tendencies, not certainties.
Delivery
Digital delivery via the PlexusDx Results Portal. Typically available within moments (outside of business hours may take slightly longer).
Eligibility
Add-on report for existing PlexusDx genetic test customers only. Requires prior PlexusDx DNA data. No test kit included.
Is this right for you

Who this report is for

This report is for you if

People who already took a PlexusDx genetic test and want to explore healthy aging
Anyone curious how their genes relate to longevity, cellular energy, and heart health pathways
People who like to bring specific, DNA-based questions to their doctor
Anyone building a long-term wellness and healthspan plan

This report is not

People who have not yet taken a PlexusDx genetic test (this report needs your existing DNA data)
Anyone looking for a medical diagnosis, treatment plan, or a prediction of lifespan
People who want lab bloodwork values (this is a genetic report, not a blood test)
Anyone under 18
What you receive

Everything included with your report

36 genetic insights

A clear readout of 36 markers across 26 genes tied to healthy aging.

Plain-English explanations

Each insight is explained in everyday language, with the gene and what it relates to.

Five focus areas

Your results grouped into longevity, NAD and energy, telomeres, heart health, and cholesterol.

Discussion points for your provider

Practical, balanced points you can bring to a doctor or other health professional.

Instant digital delivery

Your report appears in the PlexusDx Results Portal, usually within moments.

One test for life

Your DNA does not change, so you can revisit these insights any time.

Your ecosystem

Part of your bigger picture

Your results live in the PlexusDx Results Portal, alongside your other genetic reports and supplement guidance. One DNA sample keeps unlocking more over time.

Report type
Genetic Report (Add-on)
Intended use
Wellness and education only
Where it lives
PlexusDx Results Portal

For wellness and educational use only. Not intended to diagnose, treat, cure, or prevent disease.

Built on your DNA

Turn your genes into a clearer picture of how you age

Good to know

Frequently asked questions

How many genetic insights are included?

This report includes 36 genetic insights across 26 genes tied to healthy aging. They are grouped into five areas: cellular aging and longevity, NAD and cellular energy, telomeres, heart and cardiovascular health, and cholesterol, drawing on genes such as FOXO3, SIRT1, and TERT.

Is a genetic test kit included?

No. The Longevity and Lifespan report is a digital add-on for people who already have a PlexusDx genetic test. It reads your existing DNA data and turns it into 36 new insights on healthy aging, so there is no new kit to buy or swab to send.

How soon will my report be available?

Your Longevity and Lifespan report is usually ready within moments. Because it uses the DNA data already on file from your PlexusDx genetic test, there is no waiting for lab processing. You will find it in your PlexusDx Results Portal, ready to read on any device.

Can I purchase this without a PlexusDx genetic test?

No. The Longevity and Lifespan report needs the DNA data from a completed PlexusDx genetic test, so you will want to take that test first. Once your DNA data is on file, you can add this report and any of our other genetic reports at any time.

What specific longevity genes and pathways does this report analyze?

The report covers 36 variants across pathways studied in healthy aging. These include longevity-associated genes like FOXO3, IGF1R, and TP53, sirtuin and NAD genes such as SIRT1 and SIRT6, telomere genes including TERT and KL (Klotho), and heart and cholesterol genes like PCSK9 and CETP.