

GHK-Cu Rx Protocol
Compounded GHK-Cu cream via licensed providers. 0.2%, 0.5% or 2% strength, your provider in your corner.
THE BENEFITS
What GHK-Cu is for.
THE SCIENCE
A copper peptide your body already makes.
GHK-Cu signals skin repair and collagen. Blood levels fall by more than half between ages 20 and 60. Your prescription cream comes in 0.2%, 0.5% or 2%.
THE GOAL
Show up to your day differently
You want skin that looks firmer and smoother, with fewer fine lines.
HOW LONG IT TAKES
Real results take real time
GHK-Cu builds over weeks, not days. Your provider adjusts your plan as you go.
YOUR GENETICS
Built around your biology, not someone else's average
The optional GLP-1 & Peptide Pathways Genetic Test gives you 17 Longevity insights, including FOXO3, to share with your provider.
PEER-REVIEWED RESEARCH
3
GHK-Cu is a tripeptide of glycine, histidine, and lysine that binds copper(II) and signals tissue repair, collagen synthesis, and stem cell migration in connective tissues. Source: Pickart & Margolina, International Journal of Molecular Sciences, 2018.
Compounded medications are not FDA-approved or evaluated for safety, effectiveness, or quality. PlexusDx coordinates care; licensed providers evaluate and prescribe when clinically appropriate; partner pharmacies dispense and label medications.
READY?
A plan your provider designs around you.
A short online visit · Cards are charged once your prescription is sent to the pharmacy.
Overview
Compounded GHK-Cu is a copper-binding tripeptide prescribed by licensed providers as a pharmacy-grade topical cream in 0.2%, 0.5% or 2% strength. You choose your strength in your online visit and your provider reviews it. One price per plan covers your provider visit, prescription, medication, and shipping: $59 to $129 a month by strength and plan length, from $59/mo for 0.2% cream on a 12-month plan ($708 billed up front) to $129 month to month for 2% cream. No membership fee.
- Topical cream in 0.2%, 0.5% or 2% strength, applied as your provider directs
- GHK-Cu mechanism — copper-binding tripeptide supporting tissue repair, collagen synthesis, and cellular renewal pathways
- 0.2% cream $89, $79, $69 or $59 a month; 0.5% cream $99, $89, $79 or $69; 2% cream $129, $119, $109 or $99 (1-, 3-, 6- or 12-month plans) — 3-, 6- and 12-month plans are charged once, up front, and renew automatically
- Real medical authority — U.S.-licensed providers, no AI prescriptions
- 14 Skin Health and 9 Tissue Repair genetic insights — optional GLP-1 & Peptide Pathways Genetic Test, $99 as an add-on after your first month
The optional GLP-1 & Peptide Pathways Genetic Test analyzes 14 Skin Health and 9 Tissue Repair insights, plus 17 Longevity insights including FOXO3, drawn from a 150+ insight panel across 14 pathways. Available for $99 as an add-on after your first month of treatment.
Pricing
What GHK-Cu Cream costs
Your price depends on your cream's strength and your plan length.
Starts at $59/mo
·0.2% cream, 12-month plan, $708 billed up front · $89 month to month (0.2% cream)
No membership fee.
Price by strength and plan length
| Strength | 1-month plan | 3-month plan | 6-month plan | Best value 12-month plan |
|---|---|---|---|---|
| 0.2% cream Lowest strength | 1-month plan $89/mo Billed monthly | 3-month plan $79/mo $237 billed up front | 6-month plan $69/mo $414 billed up front | Best value 12-month plan Starts at $59/mo $708 billed up front |
| 0.5% cream Middle strength | 1-month plan $99/mo Billed monthly | 3-month plan $89/mo $267 billed up front | 6-month plan $79/mo $474 billed up front | Best value 12-month plan $69/mo $828 billed up front |
| 2% cream Highest strength | 1-month plan $129/mo Billed monthly | 3-month plan $119/mo $357 billed up front | 6-month plan $109/mo $654 billed up front | Best value 12-month plan $99/mo $1,188 billed up front |
3-, 6- and 12-month plans are charged once, up front, and renew automatically. Cancel future renewals anytime.
HSA and FSA cards accepted at checkout · Pay over time on 3-, 6- and 12-month plans
Provider-reviewed strength
Cards are charged once your prescription is sent to the pharmacy.
A short online visit. A licensed provider decides whether a prescription is right for you.
WHAT HAPPENS NEXT
After you order
What happens once your intake is in.
LICENSED REVIEW
Provider review & prescription
503A COMPOUNDING
Pharmacy ships your medication
CARE THAT CONTINUES
Ongoing provider care
FLEXIBILITY
Manage your plan
OUR COMMITMENT
YOUR PLAN
What's included
Your provider, your pharmacy, your direct-to-door shipping — everything in your GHK-Cu Cream plan.
Licensed, online
Licensed providers across the U.S.
503A compounded
Pharmacy-grade GHK-Cu cream prepared in the strength you and your provider choose.
Direct-to-door
Discreet packaging. Ships from U.S. partner pharmacy.
One price per plan
Your plan price covers your provider, prescription, medication and shipping. No membership fee.
Provider-reviewed
Your plan renews automatically. 1-month plans ship a 1-month supply; longer plans ship a 3-month supply in each box.
Provider check-ins
Your provider follows your progress and adjusts your dose when appropriate.
Manage your plan
Manage your plan in your patient portal. Cancel future renewals anytime.
The optional GLP-1 & Peptide Pathways Genetic Test analyzes 17 Longevity insights including FOXO3 — a longevity gene linked to living past 100 — drawn from a 150+ insight panel across 14 pathways. Available for $99 as an add-on after your first month of treatment.
CLINICAL FIT CHECK
Is this protocol right for you?
We lead with safety considerations first. If any exclusion applies to you, stop here and speak with your primary care provider before starting intake.
Skip this protocol if…
MALIGNANCY HISTORY
Active or recent cancer diagnosis
PREGNANCY STATUS
Pregnant, breastfeeding, or planning pregnancy
ORGAN DISEASE
Severe hepatic, renal, or cardiovascular disease
KNOWN ALLERGY
Active malignancy, Wilson's disease, or hypersensitivity to GHK-Cu or compounded ingredients
You're a fit if…
SKIN & TISSUE
Adults focused on skin firmness, texture or fine lines
CLINICAL OVERSIGHT
Want oversight from a U.S.-licensed provider
PRICING TRANSPARENCY
Want every price published up front
DATA-GUIDED CARE
You prefer clinical decisions informed by your personal health data
PROVIDER VERDICT
Your licensed provider confirms final eligibility during intake review. No medication ships without their sign-off.
Built differently
What makes PlexusDx different
Five things every shopper deserves before they sign up.
Genetics-informed care from a complete precision health platform
17 Longevity insights via the GLP-1 & Peptide Pathways Genetic Test — across 14 pathways, 49 peptides. The only telehealth peptide protocol with a genetic testing layer.
Radically transparent
Every plan and every price published.
One plan price
One price for intake, Rx, medication, shipping.
Online clinical oversight
No in-person visits. A short online visit with a licensed provider.
No membership gate
Your first dollar goes toward care, not a membership fee.
Clinical details
Clinical details
How this compound works and what lab work is involved.
Compound spec
Class
Copper tripeptide
tissue and skin signaling peptide
Route
Topical Cream
provider-determined cadence
Half-life
Provider-set
cadence depends on dose and tolerance
Compounded by
503A pharmacy
licensed US partner
About this compound
How this compound compares
GHK-Cu Rx Protocol — FAQ
Answers before you start
Straight answers on pricing, formulation, and what's included — pulled from the questions Longevity patients ask most.
PRICING
How much does GHK-Cu cream cost?
INCLUSIONS
What's included in every plan?
STRENGTH
How is my strength chosen?
MECHANISM
What is GHK-Cu and how does it support skin and tissue pathways?
GENETICS
Do I need my GLP-1 & Peptide Pathways Genetic Test before starting?
FLEXIBILITY
What if I need a different strength or medication?
PAYMENT
Can I use my HSA or FSA card, or pay over time?
DELIVERY
Can I pause or change my deliveries?
Start your GHK-Cu Rx protocol today
Three reasons to start your longevity protocol with PlexusDx.