THE BENEFITS

What GHK-Cu is for.

THE SCIENCE

A copper peptide your body already makes.

GHK-Cu signals skin repair and collagen. Blood levels fall by more than half between ages 20 and 60. Your prescription cream comes in 0.2%, 0.5% or 2%.

THE GOAL

Show up to your day differently

You want skin that looks firmer and smoother, with fewer fine lines.

HOW LONG IT TAKES

Real results take real time

GHK-Cu builds over weeks, not days. Your provider adjusts your plan as you go.

YOUR GENETICS

Built around your biology, not someone else's average

The optional GLP-1 & Peptide Pathways Genetic Test gives you 17 Longevity insights, including FOXO3, to share with your provider.

PEER-REVIEWED RESEARCH

3

GHK-Cu is a tripeptide of glycine, histidine, and lysine that binds copper(II) and signals tissue repair, collagen synthesis, and stem cell migration in connective tissues. Source: Pickart & Margolina, International Journal of Molecular Sciences, 2018.

Compounded medications are not FDA-approved or evaluated for safety, effectiveness, or quality. PlexusDx coordinates care; licensed providers evaluate and prescribe when clinically appropriate; partner pharmacies dispense and label medications.

READY?

A plan your provider designs around you.

Start your intake

A short online visit · Cards are charged once your prescription is sent to the pharmacy.

Overview

Compounded GHK-Cu is a copper-binding tripeptide prescribed by licensed providers as a pharmacy-grade topical cream in 0.2%, 0.5% or 2% strength. You choose your strength in your online visit and your provider reviews it. One price per plan covers your provider visit, prescription, medication, and shipping: $59 to $129 a month by strength and plan length, from $59/mo for 0.2% cream on a 12-month plan ($708 billed up front) to $129 month to month for 2% cream. No membership fee.

  • Topical cream in 0.2%, 0.5% or 2% strength, applied as your provider directs
  • GHK-Cu mechanism — copper-binding tripeptide supporting tissue repair, collagen synthesis, and cellular renewal pathways
  • 0.2% cream $89, $79, $69 or $59 a month; 0.5% cream $99, $89, $79 or $69; 2% cream $129, $119, $109 or $99 (1-, 3-, 6- or 12-month plans) — 3-, 6- and 12-month plans are charged once, up front, and renew automatically
  • Real medical authority — U.S.-licensed providers, no AI prescriptions
  • 14 Skin Health and 9 Tissue Repair genetic insights — optional GLP-1 & Peptide Pathways Genetic Test, $99 as an add-on after your first month

The optional GLP-1 & Peptide Pathways Genetic Test analyzes 14 Skin Health and 9 Tissue Repair insights, plus 17 Longevity insights including FOXO3, drawn from a 150+ insight panel across 14 pathways. Available for $99 as an add-on after your first month of treatment.

Why trust PlexusDx

Compliance

503A pharmacy-grade medication

Your compounded GHK-Cu Cream is prepared by a licensed 503A compounding pharmacy for your prescription — not mass-manufactured.

Coverage

Licensed providers across the U.S.

Your provider confirms availability in your state at your visit.

Privacy

HIPAA-compliant platform

Protected under HIPAA. Never sold or shared without your consent. Manage your plan in your patient portal at my.plexusdx.com.

Pricing

Transparent pricing

Your price depends on your cream's strength and your plan length.

Pricing

What GHK-Cu Cream costs

Your price depends on your cream's strength and your plan length.

Starts at $59/mo

·

0.2% cream, 12-month plan, $708 billed up front · $89 month to month (0.2% cream)

No membership fee.

Price by strength and plan length

GHK-Cu Cream prices by strength and plan length: price per month, and the amount billed
Strength 1-month plan 3-month plan 6-month plan Best value 12-month plan
0.2% cream Lowest strength 1-month plan $89/mo Billed monthly 3-month plan $79/mo $237 billed up front 6-month plan $69/mo $414 billed up front Best value 12-month plan Starts at $59/mo $708 billed up front
0.5% cream Middle strength 1-month plan $99/mo Billed monthly 3-month plan $89/mo $267 billed up front 6-month plan $79/mo $474 billed up front Best value 12-month plan $69/mo $828 billed up front
2% cream Highest strength 1-month plan $129/mo Billed monthly 3-month plan $119/mo $357 billed up front 6-month plan $109/mo $654 billed up front Best value 12-month plan $99/mo $1,188 billed up front

3-, 6- and 12-month plans are charged once, up front, and renew automatically. Cancel future renewals anytime.

HSA and FSA cards accepted at checkout · Pay over time on 3-, 6- and 12-month plans

Online visit with a licensed provider Prescription, if appropriate Compounded GHK-Cu Cream Shipping included

Provider-reviewed strength

You choose 0.2%, 0.5% or 2% cream in your online visit. Your provider reviews your choice before anything is prescribed.

Start your online visit

Cards are charged once your prescription is sent to the pharmacy.

A short online visit. A licensed provider decides whether a prescription is right for you.

WHAT HAPPENS NEXT

After you order

What happens once your intake is in.

After your visit

LICENSED REVIEW

Provider review & prescription

A licensed U.S. provider reviews your online visit and decides whether a prescription is right for you.

Once prescribed

503A COMPOUNDING

Pharmacy ships your medication

Your compounded GHK-Cu cream ships from a US 503A pharmacy prepared specifically for your prescription. A 503A pharmacy is a state-licensed compounding facility regulated by FDA and state boards of pharmacy that prepares medications individually for a specific patient based on a valid prescription. Dosing schedule included.

Ongoing

CARE THAT CONTINUES

Ongoing provider care

Your provider follows your progress and adjusts your treatment when appropriate.

Anytime

FLEXIBILITY

Manage your plan

Manage your plan in your patient portal at my.plexusdx.com. Cancel future renewals anytime.

OUR COMMITMENT

Cards are charged once your prescription is sent to the pharmacy. Cancel future renewals anytime.

YOUR PLAN

What's included

Your provider, your pharmacy, your direct-to-door shipping — everything in your GHK-Cu Cream plan.

PROVIDER

Licensed, online

Licensed providers across the U.S.

PHARMACY

503A compounded

Pharmacy-grade GHK-Cu cream prepared in the strength you and your provider choose.

SHIPPING

Direct-to-door

Discreet packaging. Ships from U.S. partner pharmacy.

PLAN PRICING

One price per plan

Your plan price covers your provider, prescription, medication and shipping. No membership fee.

WHAT YOU WON'T PAY
Membership fee
Consult charge
Hidden fees
REFILLS

Provider-reviewed

Your plan renews automatically. 1-month plans ship a 1-month supply; longer plans ship a 3-month supply in each box.

MONITORING

Provider check-ins

Your provider follows your progress and adjusts your dose when appropriate.

FLEXIBILITY

Manage your plan

Manage your plan in your patient portal. Cancel future renewals anytime.

Optional add-on
Available post-enrollment

The optional GLP-1 & Peptide Pathways Genetic Test analyzes 17 Longevity insights including FOXO3 — a longevity gene linked to living past 100 — drawn from a 150+ insight panel across 14 pathways. Available for $99 as an add-on after your first month of treatment.

17
Pathway insights
150+
Total panel
14
Pathways
$99
Add-on
Featured SNP
FOXO3
a longevity gene linked to living past 100

CLINICAL FIT CHECK

Is this protocol right for you?

We lead with safety considerations first. If any exclusion applies to you, stop here and speak with your primary care provider before starting intake.

SAFETY EXCLUSIONS

Skip this protocol if…

MALIGNANCY HISTORY

Active or recent cancer diagnosis

PREGNANCY STATUS

Pregnant, breastfeeding, or planning pregnancy

ORGAN DISEASE

Severe hepatic, renal, or cardiovascular disease

KNOWN ALLERGY

Active malignancy, Wilson's disease, or hypersensitivity to GHK-Cu or compounded ingredients

ELIGIBLE

You're a fit if…

SKIN & TISSUE

Adults focused on skin firmness, texture or fine lines

CLINICAL OVERSIGHT

Want oversight from a U.S.-licensed provider

PRICING TRANSPARENCY

Want every price published up front

DATA-GUIDED CARE

You prefer clinical decisions informed by your personal health data

PROVIDER VERDICT

Your licensed provider confirms final eligibility during intake review. No medication ships without their sign-off.

Built differently

What makes PlexusDx different

Five things every shopper deserves before they sign up.

THE DIFFERENTIATOR

Genetics-informed care from a complete precision health platform

17 Longevity insights via the GLP-1 & Peptide Pathways Genetic Test — across 14 pathways, 49 peptides. The only telehealth peptide protocol with a genetic testing layer.

TRANSPARENCY

Radically transparent

Every plan and every price published.

PRICING

One plan price

One price for intake, Rx, medication, shipping.

CLINICAL

Online clinical oversight

No in-person visits. A short online visit with a licensed provider.

NO GATE

No membership gate

Your first dollar goes toward care, not a membership fee.

Clinical details

Clinical details

How this compound works and what lab work is involved.

Compound spec

Class

Copper tripeptide

tissue and skin signaling peptide


Route

Topical Cream

provider-determined cadence


Half-life

Provider-set

cadence depends on dose and tolerance


Compounded by

503A pharmacy

licensed US partner

How it works

About this compound

GHK-Cu is a naturally occurring copper-binding tripeptide (glycyl-L-histidyl-L-lysine) that signals tissue repair, collagen and elastin synthesis, and stem cell migration. GHK-Cu levels decline with age, and exogenous administration is intended to support connective tissue resilience and cellular renewal pathways.

GHK-Cu Cream comes in 0.2%, 0.5% and 2% strengths. You choose a strength in your online visit and your provider reviews it before anything is prescribed; your price depends on the strength and your plan length.

See how PlexusDx customers describe their precision health journey — read Customer Stories.

Why it matters

The optional GLP-1 & Peptide Pathways Genetic Test analyzes 14 Skin Health and 9 Tissue Repair insights, plus 17 Longevity insights including FOXO3. Available for $99 as an add-on after your first month of treatment.

Lab requirements
No blood work required at intake. Blood testing is available at patient election and may be recommended by your provider based on your individual health history.
NOT REQUIRED
Compare Compounds

How this compound compares

Compound
Mechanism
Route
Monthly price
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$119/mo (12-mo plan) · $159 month to month
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MIC + B12
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$69/mo (12-mo plan) · $99 month to month
Glutathione
Endogenous antioxidant
Injection
$69/mo (12-mo plan) · $99 month to month
You're viewingGHK-Cu Cream
Copper-binding tripeptide
Topical cream
$59/mo (0.2%, 12-mo plan) · $89 month to month
Lipo C
Lipotropic + L-carnitine
Injection
$109/mo (12-mo plan) · $139 month to month
PT-141
Melanocortin receptor agonist
Injection
$159/mo (12-mo plan) · $189 month to month

GHK-Cu Rx Protocol — FAQ

Answers before you start

Straight answers on pricing, formulation, and what's included — pulled from the questions Longevity patients ask most.

PRICING

How much does GHK-Cu cream cost?

GHK-Cu cream starts at $59/mo for 0.2% on a 12-month plan ($708 billed up front), or $89 month to month. 0.5% runs $69 to $99 a month and 2% runs $99 to $129. 3-, 6- and 12-month plans are charged once, up front, and renew automatically. Cancel future renewals anytime.

INCLUSIONS

What's included in every plan?

Every GHK-Cu plan includes your online visit with a licensed provider, your prescription, your compounded GHK-Cu cream, and shipping to your door. There is no membership fee and no consult charge. Your price depends on your cream's strength and your plan length. Cancel future renewals anytime.

STRENGTH

How is my strength chosen?

You choose 0.2%, 0.5% or 2% GHK-Cu cream in your online visit. Your provider reviews your choice and your health history before anything is prescribed, and you get directions with your prescription. Your price depends on your cream's strength and your plan length.

MECHANISM

What is GHK-Cu and how does it support skin and tissue pathways?

GHK-Cu is a copper tripeptide — a naturally occurring three-amino-acid sequence (glycyl-L-histidyl-L-lysine) bound to copper that functions as a tissue and skin signaling peptide, modulating cellular signaling pathways related to extracellular matrix remodeling, antioxidant defense, and connective tissue maintenance. Compounded topical GHK-Cu is prescribed by a licensed provider and prepared by a compounding pharmacy for your individual prescription.

GENETICS

Do I need my GLP-1 & Peptide Pathways Genetic Test before starting?

No. You can start GHK-Cu first. The optional GLP-1 & Peptide Pathways Genetic Test is a $99 add-on after your first month. It analyzes 150+ insights across 14 pathways, including 14 Skin Health and 9 Tissue Repair insights. It reports on your biology. It does not determine which medication you use; your provider does.

FLEXIBILITY

What if I need a different strength or medication?

Your provider reviews your strength and how your skin responds. If your provider recommends a different strength or medication, unused prepaid value is credited toward it and you pay only the difference. Your price depends on your cream's strength and your plan length. Cancel future renewals anytime.

PAYMENT

Can I use my HSA or FSA card, or pay over time?

Yes. HSA and FSA cards are accepted at checkout. Eligibility depends on your HSA or FSA plan, so check with your plan administrator. On 3-, 6- and 12-month plans you can also pay over time: pay-later options show at checkout when you're eligible. Pay over time isn't offered on 1-month plans.

DELIVERY

Can I pause or change my deliveries?

Yes. Pause a delivery or update your shipping address in your patient portal at my.plexusdx.com.

─── READY TO START

Start your GHK-Cu Rx protocol today

Three reasons to start your longevity protocol with PlexusDx.

ENROLL TODAY
Ready to Start Your GHK-Cu Rx Protocol?

Order your GHK-Cu Rx protocol today. Add 17 Longevity, 14 Skin Health and 9 Tissue Repair genetic insights after your first month, including FOXO3. Make informed decisions supported by clinical oversight and your unique biology.

Start Today →
A short online visit · Cards are charged once your prescription is sent to the pharmacy.
TRANSPARENCY
Every plan, every price
Published before you enroll. No intake required to see prices.
Radically transparent
PLAN PRICING
One price per plan
Online visit, prescription, medication and shipping: one price per plan.
No surprise billing
GENETICS-INFORMED
Your biology, your care
150+ insights across 14 pathways, available post-enrollment for $99.
The only telehealth layer
Important Information
Compounded medications are not approved by the FDA or reviewed for quality, safety, or efficacy.

PlexusDx coordinates care; licensed providers evaluate and prescribe when clinically appropriate; partner pharmacies dispense and label medications.

The GLP-1 & Peptide Pathways Genetic Test analyzes how your genes influence peptide-related biological pathways. It does not recommend, prescribe, or determine which peptides you should use. Consult a qualified healthcare provider before beginning any peptide protocol.