Overview
66
genetic insights
17
traits
26
genes
5
focus areas

The Weight & Body Fat Genetic Report turns your existing PlexusDx DNA into 66+ insights across 17 weight-related traits, covering appetite and eating behavior, body composition and fat distribution, macronutrient response, blood sugar and metabolism, and how you respond to weight loss and regain.

Genes in this report
MC4RADIPOQFTOADRB3ADRB2APOA2
Focus areas
Appetite & eating behaviorBody composition & fat distributionMacronutrient responseBlood sugar & metabolismWeight-loss & regain response

For wellness and educational use only. Not intended to diagnose, treat, cure, or prevent disease.

HIPAA-compliant platform
Data never sold
One test for life

What you'll learn

How your appetite is wired

Whether your genes lean toward stronger hunger signals, more snacking, or emotional eating, so you can plan around them.

Where your body stores fat

How your DNA relates to body composition and fat distribution, which can shape realistic goals.

How you respond to fats and fiber

Whether your body handles dietary fat and fiber more or less efficiently, useful for tuning your plate.

Your blood sugar tendencies

How your genes relate to blood sugar response and the way you turn food into energy.

How you lose and regain weight

Genetic tendencies in weight-loss response and regain risk that can inform which strategies fit you.

Where to focus first

A clear starting point so you can take one or two areas to your provider or dietitian instead of guessing.

For an educational overview, see our learning resources

What your report covers

Your report looks at 66 markers across 17 weight-related traits, grouped into five plain-language areas. Each shows how your genes relate to appetite, body composition, and how you respond to food and dieting, not a diagnosis.

Appetite & eating behavior

How your genes may shape hunger, fullness, cravings, and the pull toward emotional or impulse eating.

Hunger and fullness signalsSnacking and cravingsEmotional eating
Featured genesMC4RADIPOQFTO

Body composition & fat distribution

How your genes may relate to where you store fat, your body composition, and lean muscle mass.

Body compositionFat distributionLean muscle mass
Featured genesFTOADRB3ADRB2

Macronutrient response

How your body may respond to dietary fat, fiber, and the balance of macronutrients you eat.

Dietary fat responseFiber responseFat sensitivity
Featured genesAPOA2FABP2PPARG

Blood sugar & metabolism

How your genes may influence blood sugar response and the way your body turns food into energy.

Blood sugar responseSugar sensitivity
Featured genesTCF7L2SLC2A2ADCY5

Weight-loss & regain response

How your body may respond to weight loss and the tendency to regain, which can shape strategy.

Weight-loss responseWeight-regain tendency
Featured genesADRB2ADRB3UCP1

You do not have to act on all of it. Pick one or two areas, talk them over with your provider or a dietitian, and build from there. This report is for wellness and education, not diagnosis.

How it works

1
A plain-language summary of what the finding means.
2
The genetic variants and pathway context behind it.
3
Practical lifestyle and discussion points for you and your provider.
4
Clear framing that insights show tendencies, not certainties.
Delivery
Digital delivery via the PlexusDx Results Portal. Typically available within moments (outside of business hours may take slightly longer).
Eligibility
Add-on report for existing PlexusDx genetic test customers only. Requires prior PlexusDx DNA data. No test kit included.
Is this right for you

Who this report is for

This report is for you if

People who have struggled to lose weight despite effort and want to understand why
Anyone tailoring nutrition or training to their biology
People working with a dietitian, coach, or provider who want better inputs
Existing PlexusDx customers who want more from their DNA data
Anyone curious about the genetics behind appetite and metabolism

This report is not

Anyone looking for a diagnosis or a prescription
People who want a guaranteed number on the scale
Those expecting genetics to replace diet and lifestyle
Anyone under 18
What you receive

Everything included with your report

A plain-English report

Your results organized into clear, readable sections, no science degree required.

Your exact genotypes

Every variant we analyzed, with the gene and rsID, so nothing is hidden.

Trait-by-trait context

How each variant relates to the traits in this report, in everyday language.

Guidance you can act on

Practical, non-prescriptive context to bring to your provider, coach, or dietitian.

A report for life

Your DNA does not change, so you can revisit these insights any time.

Your ecosystem

Part of your bigger picture

Your results live in the PlexusDx Results Portal, alongside your other genetic reports and supplement guidance. One DNA sample keeps unlocking more over time.

Report type
Genetic Report (Add-on)
Intended use
Wellness and education only
Where it lives
PlexusDx Results Portal

For wellness and educational use only. Not intended to diagnose, treat, cure, or prevent disease.

Built on your DNA

Turn your DNA into a smarter weight plan.

Good to know

Frequently asked questions

How many genetic insights are included?

Over 65 genetic insights related to weight regulation and body composition.

Is a genetic test kit included?

No. This is a digital add-on report that uses existing PlexusDx DNA data.

How soon will my report be available?

Typically within moments of purchase. Availability outside business hours may take longer.

Can I purchase this without a PlexusDx genetic test?

No. A completed PlexusDx genetic test is required to unlock this report.

What weight regulation and body composition genes does this report analyze?

This report analyzes 66 genetic variants related to appetite and hunger signaling (LEPR, MC4R, FTO), fat distribution and body composition (ADIPOQ, ADRB2, TFAP2B), macronutrient response (APOA2, FABP2, PPARG), and blood sugar regulation (TCF7L2). Use it to help personalize nutrition and lifestyle, not as medical advice.