MEDVi vs SkinnyRx vs PlexusDx: Prices, Routes & Care

Last reviewed: May 12, 2026 Last updated: September 22, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Director, with a PharmD and MBA specializing in pharmacogenomics and clinical product development. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

This article is part of the PlexusDx Education Hub — evidence-based guidance on GLP-1 therapies and weight-management care. Browse all Peptides & GLP-1 education

Editorial note: PlexusDx publishes this editorial review and offers one of the programs discussed. PlexusDx is not affiliated with MEDVi and has no commercial relationship with the companies named in this article; there are no affiliate links. Information is based on the sources and dates shown.

As of September 22, 2026, only two of these three providers publish prices you can read before intake. MEDVi's compounded semaglutide injection is $179 for the first month for new patients and $299 per billing cycle at refill, as displayed September 22, 2026; its compounded tirzepatide injection is $399 at MEDVi's ongoing month-to-month rate, verified September 22, 2026 (first-month offer shown after the questionnaire), and its tablet runs about $70 a month over its injection rate for the same compound with no tablet total published. SkinnyRx lists compounded semaglutide, tirzepatide injection and tirzepatide tablets, but every price and policy on its site is script-rendered and unreadable, so nothing is assigned to it here. PlexusDx publishes flat month-to-month rates on each product page: Semaglutide Injection $189/mo, Tirzepatide Injection $289/mo, Semaglutide Oral $289/mo and Tirzepatide Oral $349/mo.

Three-provider medication and route menu

MEDVi's program page lists compounded semaglutide injection, compounded tirzepatide injection and a compounded semaglutide daily dissolvable tablet, plus branded Wegovy® and Zepbound® products on a separate membership-plus-medication-cost track. SkinnyRx's product URLs point to compounded semaglutide, a tirzepatide injectable and tirzepatide tablets. PlexusDx offers Semaglutide Injection, Tirzepatide Injection, Semaglutide Oral, Tirzepatide Oral and a Microdose GLP-1 Protocol in which the provider selects one of four low-dose variants.

All compounded products from all three are prepared by state-licensed compounding pharmacies and are not FDA-approved drug products; they are not the same as Wegovy®, Ozempic®, Zepbound® or Mounjaro®. The FDA's page on unapproved GLP-1 drugs explains the distinction. A compounded tablet is also not the FDA-approved oral product.

Same-term injection prices

The first table compares month-to-month compounded injection rates only. MEDVi figures come from MEDVi's program page, which renders prices by script, and start.medvi.org; confirm in MEDVi's official offer. SkinnyRx cells reflect what could be read on SkinnyRx's site. PlexusDx figures are from its product pages.

PlexusDx publishes this comparison and offers one of the programs discussed. Information is based on the sources and dates shown.

Checked September 22, 2026. Month-to-month only; PlexusDx 3- and 6-month commitment tiers are listed separately below.

PlexusDx also advertises per-month rates on commitments, kept apart because they are not month-to-month: Semaglutide Injection $169/mo on a 3-month commitment (commitment total $507) or $149/mo on a 6-month commitment (commitment total $894); Tirzepatide Injection $269/mo (commitment total $807) or $249/mo (commitment total $1,494). The payment schedule and any refund terms for a multi-month plan are shown at checkout. MEDVi offers 3-, 6- and 12-month bundles; their rates appear in its signup flow and are not published here.

Oral programs in a separate comparison

Oral products are priced apart from injections and should never share a row with them.

Checked September 22, 2026. Oral rates are month-to-month; PlexusDx Semaglutide Oral is $269/mo and $249/mo, and Tirzepatide Oral $299/mo and $279/mo, on 3- and 6-month commitments respectively.

Support, refund, and shipping terms

MEDVi publishes the most complete service list: physician review, a personalized plan, 1:1 guidance, a metabolic report, free dietitian visits and care coaching, unlimited 24/7 support, fast free shipping and HSA/FSA acceptance. Its refund policy allows a full refund only within the first 72 hours without services or on medical disqualification; monthly plans are not refunded for the month of cancellation, and cancellation needs 72 hours' notice before the next billing date. How customers describe that support is covered in MEDVi customer reviews.

SkinnyRx's support, refund and shipping terms could not be read, so this post assigns it none. PlexusDx covers the provider visit, prescription, medication and shipping in one price, charges $0 until your provider approves, and cancels anytime with no fees on month-to-month plans. Care comes from an independent network of U.S.-licensed clinicians through a state-licensed telehealth platform, for eligible adults in all 50 states; five states require a scheduled video consultation.

Evidence limits and clinical review

The clinical-trial results behind branded semaglutide and tirzepatide do not establish identical outcomes for any compounded injection or oral formulation, from any of the three providers. A licensed pharmacy or a licensed prescriber is not FDA approval of the compounded product. Whether a medication, route or dose is appropriate for you is a decision for the licensed clinician who reviews your intake, and none of the three providers' price tables changes that. Earlier versions of this post referenced regulatory correspondence involving these companies; that reference has been removed because it could not be verified directly for this update.

Choosing among the three

If you want a published price before intake, MEDVi and PlexusDx give you one and SkinnyRx does not. If the lowest first payment matters most, MEDVi's $179 first month is the lowest verified figure here, followed by its $299 refill. If you want one number that stays flat from month one and across every dose level, with no membership fee, PlexusDx publishes that on each product page. If a tirzepatide tablet is your priority, SkinnyRx lists one and PlexusDx prices one at $349/mo; MEDVi's page does not list it. For MEDVi's full menu see MEDVi Cost: Semaglutide, Tirzepatide, Membership, and Plan Prices, and for the two-brand head-to-head see MEDVi vs PlexusDx: Compare GLP-1 Prices, Plans, and Support.

Where PlexusDx fits

Compare PlexusDx weight-management plans: one monthly price that covers the provider visit, prescription, medication and shipping, no membership fee, and nothing charged until your provider approves.

A note on genetics (optional)

PlexusDx offers compounded semaglutide and tirzepatide through its Weight Management Protocols. Separately, and only if it interests you, the GLP-1 & Peptide Pathways Genetic Test ($298) analyzes 14 pathways, 49 peptides, 150+ genetic insights, including variants in FTO, MC4R and TCF7L2 that relate to appetite and glucose-handling pathways. It does not predict how you will respond to any medication and does not tell you which drug, dose or provider is right for you; it is context for a conversation with your clinician. Test before you invest, and treat genetics as a guide, not a guarantee.

This article is educational. PlexusDx is not affiliated with MEDVi and has no commercial relationship with the companies discussed. PlexusDx offers compounded semaglutide and tirzepatide through its own Weight Management Protocols; this article compares approaches in the GLP-1 telehealth space. The GLP-1 & Peptide Pathways Genetic Test analyzes how your genes influence peptide-related biological pathways. It does not predict response to any specific medication and does not recommend, prescribe, or determine which peptides you should use. Consult a qualified healthcare provider before beginning any peptide protocol. Compounded semaglutide and tirzepatide are not FDA-approved drug products; they are prepared by state-licensed compounding pharmacies under federal compounding rules and are not the same as Wegovy®, Ozempic®, Zepbound® or Mounjaro®. Zepbound® and Mounjaro® are registered trademarks of Eli Lilly and Company; Wegovy® and Ozempic® are registered trademarks of Novo Nordisk A/S. PlexusDx is not affiliated with or endorsed by either company.

Frequently Asked Questions

How much does SkinnyRx charge for semaglutide or tirzepatide?

Unknown. SkinnyRx's site lists compounded semaglutide, a tirzepatide injectable and tirzepatide tablets, but its prices, refund terms and shipping terms are script-rendered and could not be read from its official pages on September 22, 2026. This post therefore assigns SkinnyRx no figures. Confirm any SkinnyRx price at its own checkout before comparing.

What does MEDVi charge compared with PlexusDx for injections?

MEDVi's compounded semaglutide injection is $179 for the first month for new patients and $299 per billing cycle at refill, as displayed September 22, 2026; MEDVi's ongoing month-to-month rate for compounded tirzepatide injection is $399, verified September 22, 2026, with its first-month offer shown after the questionnaire. PlexusDx charges $189/mo for Semaglutide Injection and $289/mo for Tirzepatide Injection month-to-month, $110 a month less than MEDVi's ongoing rate on each compound, flat from the first month and across every dose level.

Which of the three offers an oral GLP-1 option?

All three list at least one. MEDVi lists a compounded semaglutide daily dissolvable tablet at about $70 a month over its injection rate for the same compound, with no tablet total published. SkinnyRx lists tirzepatide tablets with an unpublished price. PlexusDx prices Semaglutide Oral at $289/mo and Tirzepatide Oral at $349/mo month-to-month. None of these compounded tablets is the FDA-approved oral product.

Do any of the three charge a membership fee?

MEDVi states no membership fee for its compounded programs; its branded Wegovy and Zepbound track uses a separate membership plus medication cost. PlexusDx charges no membership fee on any plan. SkinnyRx's fee structure could not be read. Compare the recurring all-in charge for the same medication and route, not the headline rate.

Is compounded semaglutide from these providers FDA-approved?

No. Compounded semaglutide and tirzepatide from MEDVi, SkinnyRx or PlexusDx are prepared by state-licensed compounding pharmacies and are not FDA-approved drug products or equivalents of Wegovy, Ozempic, Zepbound or Mounjaro. Brand-trial results do not establish identical outcomes for compounded or oral formulations. Your licensed clinician decides whether any option is appropriate.

Sources and dates checked

• MEDVi program page (glp1.medvi.org), read September 22, 2026
• MEDVi start page (start.medvi.org), read September 22, 2026
• MEDVi cancellation and refund policy, read September 22, 2026
• SkinnyRx (skinnyrx.com) product pages, read September 22, 2026 (prices not readable)
• PlexusDx weight-management protocols collection, read September 22, 2026
• FDA: concerns with unapproved GLP-1 drugs used for weight loss

This article is part of the PlexusDx Education Hub. Browse all Peptides & GLP-1 education

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. Sources and the dates they were checked are listed at the end of the article.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services, and offers compounded GLP-1 programs through its Weight Management Protocols. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.