Last reviewed: September 5, 2026
Last updated: September 5, 2026
Written by: Jay Hastings, CEO of PlexusDx
Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.
Medically reviewed by: Jayden Lee, PharmD, EMBA
Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.
PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.
The short answer
MEDVi holds a 4.3-star rating on Trustpilot across approximately 15,000 reviews (verified September 4, 2026), a stronger review record than PlexusDx's 4.2-star rating with 76% five-star reviews and 81% at four stars or higher (verified September 4, 2026). That review advantage reflects real service elements: MEDVi includes free care coaching, a free dietitian visit, and unlimited doctor calls at no additional membership fee. Yet the pricing structure warrants close attention. MEDVi advertises a $179 first-month introductory rate for compounded semaglutide injection, but the standard refill cost is $299 per month, and that refill rate governs every subsequent fill. Over twelve months the effective cost is $289 per month ($3,468 total first year, our calculation), materially higher than the advertised entry figure. PlexusDx charges $189 per month for compounded semaglutide injection with no introductory discount, no membership fee, and full pricing published before intake—$2,268 over twelve months, $1,200 less than MEDVi in year one (our calculation). If you value extensive included support, prefer to see your price only after the questionnaire, and find MEDVi's review record persuasive, the higher ongoing rate may be justified. If you prioritize transparent published pricing and a lower recurring cost, PlexusDx offers a simpler structure at a lower annual total. Both programs use compounded medications dispensed by licensed pharmacies; neither compounded drug is FDA-approved, and a licensed clinician determines whether a prescription is appropriate for an individual patient.
Comparing introductory rates to ongoing costs?
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MEDVi vs PlexusDx: pricing and service at a glance
| Feature |
MEDVi |
PlexusDx |
| Semaglutide injection (MTM) |
$179 first month, $299 refills |
$189/month |
| Tirzepatide injection (MTM) |
$279 first month, $399 refills |
$289/month |
| 12-month cost (sema, MTM) |
$3,468 first year (our calculation) |
$2,268 (our calculation) |
| 12-month cost (tirz, MTM) |
$4,668 first year (our calculation) |
$3,468 (our calculation) |
| Pricing visibility |
After health questionnaire |
Published before intake |
| Commitment |
Cancel-anytime MTM; 3-, 6-, 12-month bundles available |
Cancel-anytime MTM; 3-month, 6-month tiers |
| Included support |
Free coaching, free dietitian visit, unlimited doctor calls |
Free check-in with Doctor of Pharmacy |
| Trustpilot rating |
4.3 stars, ~15,000 reviews |
4.2 stars, 76% five-star, 81% four-star or higher |
| Membership fee |
None (all-inclusive monthly rate) |
None |
MEDVi pricing verified September 4, 2026; PlexusDx pricing verified September 4, 2026. Trustpilot ratings verified September 4, 2026.
Breaking down MEDVi's introductory versus refill pricing
MEDVi advertises a $179 first-month introductory rate for compounded semaglutide injection, rising to a $299 standard refill rate in month two and every month thereafter (verified September 4, 2026). For compounded tirzepatide, the first month is $279, then $399 per refill (verified September 4, 2026). Both rates are all-inclusive: medication, provider consultation, unlimited support, and shipping are bundled at no extra membership fee. Dose escalation does not trigger a price increase; the monthly rate remains constant regardless of milligram strength.
Over a twelve-month course, the effective monthly cost becomes:
-
Semaglutide injection: $179 (month one) + 11 × $299 = $3,468 first year, or $289 per month on average (our calculation).
-
Tirzepatide injection: $279 (month one) + 11 × $399 = $4,668 first year, or $389 per month on average (our calculation).
The introductory discount lowers the first-year total by $120 for semaglutide and tirzepatide alike, but from year two onward the annual cost is $3,588 for semaglutide and $4,788 for tirzepatide (our calculation), reflecting the $299 and $399 refill rates across all twelve months.
MEDVi also offers compounded semaglutide in oral tablet form, adding a $70 surcharge to the injection price: $249 first month, $369 refills (verified September 4, 2026). Compounded tirzepatide is advertised in both injection and oral formulations, though no separate oral surcharge was displayed at checkout (verified September 4, 2026).
Multi-month bundles—three-, six-, and twelve-month commitments reaching a forty-eight-week maximum term—are available with 0% financing through Klarna, spread over twelve months (verified July 20, 2026). MEDVi states it is not a party to the Klarna financing agreement. Bundles are non-refundable for unused months; specific per-month rates for prepaid tiers were not published in the research dataset.
PlexusDx pricing: one published rate at every dose
PlexusDx charges $189 per month for compounded semaglutide injection and $289 per month for compounded tirzepatide injection on the month-to-month tier, with no introductory discount and no membership fee (verified September 4, 2026). Every dose—from starting strength through maintenance—carries the same monthly price. All pricing is published before intake on the product pages and the weight-management collection.
Three-month and six-month commitment tiers reduce the per-month cost:
-
Semaglutide injection: $169/month (3-month), $149/month (6-month).
-
Tirzepatide injection: $269/month (3-month), $249/month (6-month).
Over twelve months:
-
Semaglutide injection (MTM): 12 × $189 = $2,268 (our calculation).
-
Tirzepatide injection (MTM): 12 × $289 = $3,468 (our calculation).
Compared to MEDVi's first-year effective costs, PlexusDx costs $1,200 less for semaglutide ($3,468 vs $2,268) and $1,200 less for tirzepatide ($4,668 vs $3,468) in year one on a like-for-like month-to-month comparison (our calculation). From year two onward, when MEDVi's introductory discount no longer applies, the annual difference widens to $1,320 for both compounds (our calculation).
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Included services and support: MEDVi's care-coaching advantage
MEDVi bundles free care coaching, a free dietitian visit, and unlimited doctor calls into its monthly rate (verified September 4, 2026 and July 20, 2026). These are live, synchronous touchpoints with credentialed professionals, not chatbot or automated messaging. For patients who value frequent behavioral support or want scheduled accountability beyond prescription refills, these services represent material added value and may justify the higher monthly cost.
PlexusDx includes a free check-in with a Doctor of Pharmacy (verified July 20, 2026). An optional genetics add-on is available for $298 ($99 for program members), though the genetics test does not select or predict medication; the provider decides based on clinical factors (verified July 20, 2026).
Neither program charges a separate membership fee. Both offer cancel-anytime month-to-month billing with no penalty for discontinuation.
Review ratings: MEDVi's stronger Trustpilot record
MEDVi holds a 4.3-star rating on Trustpilot across approximately 15,000 reviews (verified September 4, 2026). PlexusDx holds a 4.2-star rating, with 76% of reviews at five stars and 81% at four stars or higher (verified September 4, 2026). MEDVi's higher rating and substantially larger review volume suggest a mature service with broad patient experience data.
The research dataset captured no attributable negative complaint themes from indexed Trustpilot or Reddit results for MEDVi (search performed September 4, 2026). Individual reports or anecdotes may exist on those platforms, but no systematic pattern of service-quality issues emerged in this review cycle.
Pricing transparency: before or after the questionnaire
MEDVi displays pricing after you complete the health questionnaire (verified July 20, 2026 and September 4, 2026). This approach allows the service to tailor the medication recommendation—compounded semaglutide injection, oral tablet, tirzepatide, or branded Wegovy/Zepbound pathway—before showing cost. The trade-off is that you invest time in the intake without knowing whether the monthly rate fits your budget.
PlexusDx publishes all month-to-month, three-month, and six-month pricing on product pages and the weight-management collection before you begin the intake (verified July 20, 2026). You see the full cost structure—no membership fees, no hidden charges, same price at every dose—before answering any health questions. This transparency allows immediate budget planning but does not personalize the price to your clinical profile.
Medication formats and branded-drug pathways
MEDVi offers compounded semaglutide in both injection and oral tablet forms; the tablet route adds $70 per month to the injection price ($369 refill vs $299 injection refill, verified September 4, 2026). Compounded tirzepatide is advertised in injection and oral formulations, with no separate oral surcharge displayed at checkout (verified September 4, 2026).
MEDVi also provides a pathway to branded Wegovy and Zepbound for $99 per month membership fee plus the separate medication cost, which varies by insurance and pharmacy (verified September 4, 2026). This dual-track model lets MEDVi pivot to FDA-approved branded drugs if compounded supply tightens or if a patient's insurance covers branded GLP-1 medication.
PlexusDx offers compounded semaglutide and tirzepatide in injection form at the pricing shown above, plus oral semaglutide capsules at $289 per month and oral tirzepatide capsules at $349 per month (month-to-month tier). A microdose GLP-1 injection program is available at $129 per month for maintenance or re-entry scenarios.
Choose MEDVi if…
- You value frequent live touchpoints—coaching calls, dietitian consultations, and unlimited doctor access—and consider them worth the higher monthly rate.
- You prefer to complete a health questionnaire first and see personalized pricing second, rather than browsing published rates before intake.
- You are drawn to MEDVi's 4.3-star Trustpilot rating and the breadth of its ~15,000-review record.
- You want the option to finance a multi-month bundle at 0% through Klarna, spreading payments over twelve months.
- You anticipate needing both compounded and branded-drug pathways and want one service that offers Wegovy/Zepbound alongside compounded semaglutide and tirzepatide.
Choose PlexusDx if…
- You prioritize a lower recurring cost: $189/month for semaglutide injection saves $1,200 in year one versus MEDVi's first-year effective cost, and $1,320 annually from year two onward (our calculation); $289/month for tirzepatide saves $1,200 in year one and $1,320 annually thereafter.
- You want every price tier—month-to-month, three-month, six-month—published on the product page before you begin the intake, with no questionnaire gate between you and the cost.
- You prefer a single flat rate that does not change with dose escalation and carries no introductory-versus-refill step-up.
- You value a free Doctor of Pharmacy check-in and are comfortable managing behavioral support independently or through other channels.
- You want the option to add genetics testing at a member rate ($99) without it affecting medication selection, which remains the provider's clinical decision.
Methodology and freshness
MEDVi pricing, billing terms, and included services were verified from checkout flows and published terms on September 4, 2026, and cross-checked against earlier research from July 20, 2026. Multi-month bundle structure and Klarna financing terms were verified July 20, 2026. Trustpilot ratings for both MEDVi and PlexusDx were captured September 4, 2026. PlexusDx pricing was verified from live product pages on September 4, 2026, with multi-month tiers confirmed July 20, 2026.
Twelve-month cost calculations, effective monthly averages, and annual savings figures are our calculations, derived by multiplying stated monthly rates over twelve months and, for MEDVi's first year, adding the introductory month and eleven refill months. All like-for-like comparisons use month-to-month tiers unless otherwise noted. We performed Reddit and Trustpilot searches for MEDVi complaint themes on September 4, 2026; no attributable negative excerpts were captured in indexed results, though individual anecdotes may exist on those platforms.
Compounded medications are not FDA-approved. The FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.
Frequently Asked Questions
Does MEDVi's $179 advertised price continue every month?
No. The $179 figure is a first-month introductory rate for compounded semaglutide injection. From month two onward, the standard refill cost is $299 per month, verified September 4, 2026. Over twelve months, the effective average is $289 per month, our calculation.
How much does MEDVi cost compared to PlexusDx over one year?
MEDVi semaglutide costs $3,468 in year one ($289 effective monthly average) versus PlexusDx's $2,268 ($189/month), a difference of $1,200 in the first year, our calculation. For tirzepatide, MEDVi costs $4,668 versus PlexusDx's $3,468, also a $1,200 first-year difference. From year two onward, the gap widens to $1,320 annually for both compounds.
What support services does MEDVi include in its monthly price?
MEDVi includes free care coaching, a free dietitian visit, and unlimited doctor calls at no additional membership fee, verified September 4, 2026. Dose increases do not raise the monthly price. PlexusDx includes a free check-in with a Doctor of Pharmacy; an optional genetics add-on is $99 for program members.
Can I see MEDVi's pricing before completing the health questionnaire?
No. MEDVi displays pricing after you complete the health questionnaire, verified July 20, 2026 and September 4, 2026. PlexusDx publishes all month-to-month, three-month, and six-month pricing on product pages before intake, allowing immediate budget comparison without answering health questions first.
Which provider has a higher Trustpilot rating?
MEDVi holds a 4.3-star rating across approximately 15,000 reviews, verified September 4, 2026. PlexusDx holds a 4.2-star rating, with 76% of reviews at five stars and 81% at four stars or higher, verified September 4, 2026. Both ratings reflect generally positive patient experiences; MEDVi's larger review volume and marginally higher average suggest a mature service record.
Sources
- PlexusDx internal comparison research: MEDVi commercial terms, multi-month bundles, and Klarna financing structure (verified July 20, 2026).
- PlexusDx internal comparison research: MEDVi included services—coaching, dietitian, unlimited doctor calls (verified July 20, 2026).
- PlexusDx competitor research dataset: MEDVi checkout-verified pricing for semaglutide injection, semaglutide tablet, and tirzepatide (verified September 4, 2026).
- PlexusDx competitor research dataset: MEDVi all-inclusive rate structure, dose-escalation pricing policy, billing terms, and branded-drug pathway (verified September 4, 2026).
- PlexusDx competitor research dataset: MEDVi Trustpilot rating (4.3 stars, ~15,000 reviews), PlexusDx Trustpilot rating (4.2 stars, distribution verified), and Reddit/Trustpilot search results (verified September 4, 2026).
- PlexusDx live product pages: semaglutide injection, tirzepatide injection, oral formulations, and microdose GLP-1 pricing (accessed September 4, 2026).
- PlexusDx canonical price list: month-to-month, three-month, and six-month tiers for all GLP-1 formulations (accessed September 4, 2026).
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Compounded medication disclosure: Compounded medications are not FDA-approved. The FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.
Medical and Editorial Standards
Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.
Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.
Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.
Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.
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