Last reviewed: September 4, 2026 Last updated: September 4, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

MEDVi charges $299/month for compounded semaglutide injection and $399/month for compounded tirzepatide on standard monthly billing, verified at checkout September 4, 2026. PlexusDx offers compounded semaglutide at $189/month and tirzepatide at $289/month on month-to-month terms, saving $110/month ($1,320/year) on either medication. MEDVi includes unlimited doctor calls, care coaching, and a dietitian visit; PlexusDx includes a free check-in with a Doctor of Pharmacy and transparent prepaid pricing that reduces the per-month rate further. MEDVi holds a 4.3-star Trustpilot rating across approximately 15,000 reviews (captured September 4, 2026), indicating broad positive reception. For price-focused buyers, PlexusDx delivers the lower ongoing cost and published multi-month rates; for buyers prioritizing integrated coaching and dietitian access at a higher price, MEDVi packages those services into every subscription.

Compare All Compounded GLP-1 Options and Pricing

Side-by-side month-to-month and prepaid rates, support inclusions, and cancellation terms.

View Weight Management Protocols →

At-a-glance comparison: MEDVi vs PlexusDx

Feature MEDVi PlexusDx
Semaglutide Injection (MTM) $299/month $189/month
Tirzepatide Injection (MTM) $399/month $289/month
Semaglutide Oral $369/month (tablet) $289/month (capsule)
Tirzepatide Oral $399/month (advertised; surcharge not verified) $349/month (capsule)
Membership Fee None (compounded programs) None
Support Inclusions Unlimited doctor calls, care coaching, dietitian visit, unlimited support Free PharmD check-in, optional genetics ($99 program rate)
Cancellation Anytime (monthly); bundles non-refundable Anytime (monthly and prepaid)
Lower Committed-Term Rates 3-, 6-, 12-month bundles available; exact rates not published Published: 3-mo $169/$269, 6-mo $149/$249 (sema/tirz, prepaid per-month equivalent)
Trustpilot Rating 4.3 stars / ~15,000 reviews (Sept 4, 2026) Not captured
Price Verified Sept 4, 2026 (checkout) July 20, 2026

Pricing breakdown: ongoing rates and 12-month normalized cost

MEDVi publishes its ongoing monthly refill rates after the health questionnaire. Standard monthly billing for compounded semaglutide injection is $299/month, compounded tirzepatide injection is $399/month, and compounded semaglutide tablet is $369/month (a $70 surcharge over injection), all verified at checkout September 4, 2026. MEDVi advertises tirzepatide in oral form, but our checkout verification did not capture a separate oral surcharge; confirm the exact rate at checkout if considering tirzepatide oral.

PlexusDx publishes month-to-month rates before intake: $189/month for compounded semaglutide injection, $289/month for compounded tirzepatide injection, $289/month for semaglutide oral capsules, and $349/month for tirzepatide oral capsules. PlexusDx also publishes lower committed-term rates on prepaid billing: a 3-month supply of semaglutide injection runs $169/month prepaid ($507 total per cycle), and a 6-month supply runs $149/month prepaid ($894 total per cycle). Tirzepatide follows the same structure: $269/month prepaid for 3 months, $249/month prepaid for 6 months.

12-month normalized cost (our calculation)

Compounded Semaglutide Injection

  • MEDVi month-to-month: 12 × $299 = $3,588/year
  • PlexusDx month-to-month: 12 × $189 = $2,268/year
  • PlexusDx 6-month prepaid: 2 cycles × $894 = $1,788/year
  • Savings: PlexusDx month-to-month saves $1,320/year ($110/month); 6-month prepaid saves $1,800/year ($150/month).

Compounded Tirzepatide Injection

  • MEDVi month-to-month: 12 × $399 = $4,788/year
  • PlexusDx month-to-month: 12 × $289 = $3,468/year
  • PlexusDx 6-month prepaid: 2 cycles × $1,494 = $2,988/year
  • Savings: PlexusDx month-to-month saves $1,320/year ($110/month); 6-month prepaid saves $1,800/year ($150/month).

Compounded Semaglutide Oral

  • MEDVi tablet ongoing: 12 × $369 = $4,428/year
  • PlexusDx oral capsule month-to-month: 12 × $289 = $3,468/year
  • Savings: PlexusDx saves $960/year ($80/month).

MEDVi offers 3-month, 6-month, and 12-month bundles with 0% financing via Klarna, but the exact bundle rates are not published in our sources. If you prefer flexible monthly billing with no financing, the ongoing rates above apply. If you prefer prepaid commitment, PlexusDx publishes its lower committed-term rates transparently before intake, and both semaglutide and tirzepatide injection see the same $40–$60/month reduction at the 3-month and 6-month tiers.

Start at $189/Month for Compounded Semaglutide, $289 for Tirzepatide

A licensed provider reviews your intake and determines whether a prescription is appropriate for you.

Start My 60-Second Intake →

About 60 seconds · $0 charged until provider approval.

Support inclusions and service model

MEDVi bundles unlimited doctor calls, care coaching, a dietitian visit, and unlimited support into every compounded GLP-1 subscription at no separate membership fee. These inclusions are documented on MEDVi's product pages and verified at checkout September 4, 2026. For individuals who want frequent clinician touchpoints, nutrition counseling, and coaching check-ins without per-call fees, MEDVi's model integrates those services into the higher monthly rate.

PlexusDx includes a free check-in with a Doctor of Pharmacy and offers an optional genetics test ($298 standalone, $99 for program members) that analyzes how your genetics may influence medication metabolism. The genetics test does not select or predict which medication will work; a licensed provider decides the prescription based on clinical history and the test results if ordered. PlexusDx's service model emphasizes transparent pricing and lower base cost, with support available but not packaged into a coached subscription tier.

Both programs ship medication to your door and operate on a telehealth intake model with licensed provider review. MEDVi's higher price reflects the integrated coaching and dietitian access; PlexusDx's lower price reflects a pharmacy-led support model without bundled coaching calls.

Trustpilot rating and review volume

MEDVi holds a 4.3-star rating on Trustpilot across approximately 15,000 reviews, captured September 4, 2026. This rating reflects broad positive reception across a large review volume. Our research sweep of Trustpilot and Reddit performed on the same date did not capture attributable negative excerpts or recurring service-quality themes from indexed results, so we cannot paraphrase specific complaints or detail support responsiveness patterns. The 4.3-star average indicates that the majority of reviewers report satisfactory experiences. Individual results vary, and readers should review recent feedback on Trustpilot and other platforms directly before committing, especially for multi-month bundles.

PlexusDx holds a 4.2-star rating on Trustpilot, with 76% of reviews at five stars and 81% at four stars or higher (captured September 4, 2026). When considering any telehealth weight-loss provider, verify recent reviews on multiple platforms and confirm cancellation terms and refund policies before purchase.

Medication availability and regulatory status

MEDVi offers compounded semaglutide injection, compounded semaglutide tablet, compounded tirzepatide injection, and compounded tirzepatide oral, plus a branded Wegovy/Zepbound pathway at a $99/month membership fee with separate medication cost. PlexusDx offers compounded semaglutide and tirzepatide in both injection and oral capsule routes, plus a microdose GLP-1 option at $129/month for maintenance or gradual ramp protocols.

Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies. MEDVi works with compounding pharmacies for its non-branded offerings; the branded pathway dispenses FDA-approved Wegovy or Zepbound through traditional channels.

Choose MEDVi if…

  • You want unlimited doctor calls, care coaching, and a dietitian visit bundled into one subscription and are willing to pay $299–$399/month for that integrated support model.
  • You prefer financing multi-month supply through Klarna installments rather than prepaying in full.
  • You value a large Trustpilot review base (15,000+ reviews, 4.3 stars) as social proof of service reliability.
  • You are considering the branded Wegovy or Zepbound pathway and want a single provider for both compounded and branded options.

Choose PlexusDx if…

  • You prioritize the lowest ongoing cost for compounded semaglutide ($189/month) or tirzepatide ($289/month) on month-to-month terms, saving $110/month versus MEDVi's standard rates.
  • You want transparent prepaid pricing published before intake, with 6-month semaglutide injection running $149/month prepaid ($1,788/year total) and 6-month tirzepatide running $249/month prepaid ($2,988/year total).
  • You prefer a pharmacy-led support model with a free Doctor of Pharmacy check-in and optional genetics testing, rather than bundled coaching and dietitian calls.
  • You want cancel-anytime flexibility on both monthly and prepaid tiers, with no non-refundable bundle terms.
  • You are interested in microdose GLP-1 for maintenance or a gradual start at $129/month, a protocol MEDVi does not advertise.

Methodology and freshness

MEDVi pricing was verified at checkout September 4, 2026, capturing ongoing monthly rates for compounded semaglutide injection ($299), semaglutide tablet ($369), and tirzepatide injection ($399). MEDVi advertises tirzepatide oral, but our checkout verification did not capture a separate surcharge; readers should confirm the exact rate at checkout. MEDVi's Trustpilot rating (4.3 stars, ~15,000 reviews) was captured September 4, 2026; our research sweep did not capture attributable negative excerpts from indexed Trustpilot or Reddit results on the same date.

PlexusDx pricing was verified July 20, 2026, from published product pages showing month-to-month rates ($189 semaglutide injection, $289 tirzepatide injection, $289 semaglutide oral, $349 tirzepatide oral, $129 microdose) and prepaid per-month equivalents (3-month and 6-month tiers). All 12-month cost calculations are our calculations using the verified monthly rates and prepaid totals. We publish only standard ongoing rates and prepaid totals; we do not publish or derive figures from lower committed-term rate structures that are not transparently disclosed before intake.

This comparison uses like-for-like month-to-month rates in both directions. MEDVi's multi-month bundle rates are not published in our sources and are excluded under our standard-rates-only methodology. Readers considering MEDVi bundles should request the exact prepaid total at checkout and compare that total to PlexusDx's published prepaid tiers before committing.

Frequently Asked Questions

Does MEDVi charge a membership fee for compounded GLP-1 programs?

No. MEDVi charges no separate membership fee for compounded semaglutide or tirzepatide programs. The monthly rate ($299 semaglutide injection, $399 tirzepatide) includes medication, clinician consult, unlimited doctor calls, care coaching, dietitian visit, and shipping. MEDVi does charge a $99/month membership fee for its branded Wegovy/Zepbound pathway, with medication cost billed separately.

How much does MEDVi's semaglutide tablet cost compared to injection?

MEDVi's compounded semaglutide tablet runs $369/month on standard monthly billing, a $70 surcharge over the $299 injection rate, verified at checkout September 4, 2026. PlexusDx offers compounded semaglutide oral capsules at $289/month, the same price as its tirzepatide injection and $80/month less than MEDVi's tablet rate.

Are MEDVi's multi-month bundles refundable if I want to stop early?

No. MEDVi's 3-month, 6-month, and 12-month bundles are non-refundable for unused months, documented in MEDVi's terms captured July 20, 2026. The standard monthly billing option is cancel-anytime with no multi-month commitment. PlexusDx offers cancel-anytime terms on both monthly and prepaid tiers.

What is PlexusDx's lowest semaglutide injection rate and how does it compare to MEDVi?

PlexusDx's 6-month prepaid tier for compounded semaglutide injection runs $149/month prepaid ($894 total per 6-month cycle, billed upfront), verified July 20, 2026. Over 12 months that totals $1,788, compared to MEDVi's standard monthly rate of $299/month totaling $3,588/year, a savings of $1,800/year or $150/month on the PlexusDx prepaid tier.

Does MEDVi include a dietitian visit in every subscription?

Yes. MEDVi includes one dietitian visit, unlimited doctor calls, care coaching, and unlimited support in every compounded GLP-1 subscription at no additional charge, verified at checkout September 4, 2026. PlexusDx includes a free check-in with a Doctor of Pharmacy and offers optional genetics testing ($99 program rate), but does not bundle dietitian or coaching calls into the base price.

Sources

  • MEDVi product pages and checkout verification, accessed September 4, 2026
  • MEDVi terms and multi-month bundle policies, accessed July 20, 2026
  • MEDVi Trustpilot profile (4.3 stars, ~15,000 reviews), accessed September 4, 2026
  • PlexusDx published pricing and product pages, accessed July 20, 2026
  • Internal PlexusDx oral capsule pricing (semaglutide $289/month, tirzepatide $349/month)

Ready to Start at $189/Month with No Membership Fee?

One all-inclusive price covers your online provider visit, prescription, medication, and shipping – no membership, no hidden fees. Complete a short intake and a licensed provider reviews your fit.

Start My Intake →

Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

Real prescribers. Published prices. No surprises.

Licensed providers in all 50 states. Online intake. No insurance, no membership required.

Start My Intake

~60 seconds · $0 charged until your provider approves