MEDVi Pricing: First-Month Rate vs Ongoing Semaglutide and Tirzepatide

Last reviewed: September 4, 2026 Last updated: September 4, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

MEDVi offers compounded semaglutide at a first-month introductory rate of $179, refilling at $299 per month, and compounded tirzepatide at a first-month rate of $279, refilling at $399 per month. The oral semaglutide tablet carries a $70 surcharge above the injection, bringing the first month to $249 and refills to $369. All compounded plans include the provider visit, medication, unlimited support, and shipping at the same monthly price regardless of dose. MEDVi also offers a branded Wegovy and Zepbound pathway through a $99 monthly membership, with medication costs billed separately at a price that depends on insurance and the product selected; the all-in cost for branded drugs was not disclosed at checkout. Over 12 months at MEDVi's ongoing refill rates, compounded semaglutide totals $3,588, and compounded tirzepatide totals $4,788. PlexusDx offers compounded semaglutide injection month-to-month at $189 ($2,268 per year) and tirzepatide injection at $289 ($3,468 per year), with no membership fee and no introductory pricing—a $1,320 annual saving on either molecule.

MEDVi pricing at a glance

All MEDVi pricing verified at checkout by PlexusDx, captured September 4, 2026. Branded pathway medication costs depend on insurance and product; final price not displayed during checkout review.

Introductory pricing vs. refill rates: the 12-month cost

MEDVi advertises first-month introductory rates that are lower than the ongoing refill price. Each fill covers four weeks, and customers submit a monthly refill form. There is no contract; MEDVi states customers may cancel anytime. To understand the true recurring cost, you must separate the advertised sign-up figure from the standard refill figure and project over 12 months.

Compounded semaglutide injection

The first-month introductory rate is $179. Every refill thereafter costs $299 per month. Over the first 12 months, the total is $179 (month one) plus 11 × $299 = $3,289, for a first-year total of $3,468 (our calculation). In subsequent years—when every fill is $299—the annual cost is 12 × $299 = $3,588 (our calculation).

Compounded semaglutide oral tablet

The oral tablet carries a $70 surcharge above the injection price. The first month is $249, and refills are $369 per month. First-year total: $249 + (11 × $369) = $4,308 (our calculation). Subsequent years: 12 × $369 = $4,428 (our calculation).

Compounded tirzepatide (injection or oral)

The first-month introductory rate is $279. Refills cost $399 per month. First-year total: $279 + (11 × $399) = $4,668 (our calculation). Subsequent years: 12 × $399 = $4,788 (our calculation). MEDVi advertises both injection and oral tirzepatide at the same price; no separate oral surcharge was displayed for tirzepatide at checkout.

Branded Wegovy and Zepbound pathway

MEDVi offers access to FDA-approved Wegovy (semaglutide) and Zepbound (tirzepatide) through a $99 monthly membership. Medication is billed separately, and the final price depends on the product selected and insurance channel. During our September 4, 2026 checkout review, the membership structure was displayed but the all-in medication cost was not disclosed, so we cannot calculate a 12-month total for the branded pathway. Membership alone totals 12 × $99 = $1,188 per year (our calculation), before medication.

PlexusDx pricing for comparison

PlexusDx offers compounded semaglutide injection month-to-month at $189, compounded tirzepatide injection at $289, and compounded semaglutide oral at $289 month-to-month. There is no membership fee, no introductory pricing tier, and no price increase when dose is adjusted. Every month costs the same. Over 12 months, semaglutide injection totals 12 × $189 = $2,268 (our calculation), and tirzepatide injection totals 12 × $289 = $3,468 (our calculation).

Customers who commit to a 3-month or 6-month prepaid plan receive a lower per-month rate. Semaglutide injection at the 6-month commitment level costs $149 per month (prepaid as 2 × $894 = $1,788 per year, our calculation), and tirzepatide injection costs $249 per month (prepaid as 2 × $1,494 = $2,988 per year, our calculation). These are prepaid figures; the per-month equivalent is our calculation.

Like-for-like: MEDVi month-to-month refills vs. PlexusDx month-to-month

All 12-month totals are our calculation, using each provider's standard ongoing rate. MEDVi first-year cost would be lower by the introductory discount ($120 for semaglutide injection, $100 for tirzepatide), but the gap widens again in year two and beyond.

What the monthly price includes

Both MEDVi and PlexusDx bundle the provider visit, medication, ongoing clinical support, and shipping into a single monthly charge. Neither charges a separate membership fee for compounded medication plans. MEDVi includes free care coaching, a free dietitian visit, and unlimited doctor calls. PlexusDx includes a free check-in with a Doctor of Pharmacy and publishes every price tier before intake. MEDVi states that dose increases do not raise the monthly price; PlexusDx uses the same policy. Both permit cancellation without a contract penalty.

Prepaid and financing options

MEDVi offers 3-month, 6-month, and 12-month prepaid bundles, though specific per-month rates for those bundles were not disclosed at checkout. MEDVi also advertises 0% financing through Klarna, spreading payments over 12 months; MEDVi states it is not a party to that financing agreement. Prepaid bundles are non-refundable for unused months. PlexusDx offers 3-month and 6-month prepaid commitments with published per-month rates: semaglutide injection drops to $169 per month on the 3-month plan and $149 per month on the 6-month plan; tirzepatide injection drops to $269 per month (3-month) and $249 per month (6-month).

Branded Wegovy and Zepbound: membership structure

MEDVi's branded pathway charges a $99 monthly membership and bills medication separately. The membership covers the provider visit and clinical support. Medication cost depends on insurance status and the product selected (Wegovy or Zepbound). During our September 4, 2026 checkout review, the membership fee was displayed but the final medication price was not, so customers should confirm the all-in monthly cost before committing. PlexusDx does not offer branded Wegovy or Zepbound; all PlexusDx GLP-1 options are compounded.

Decision factors

Pricing transparency and predictability

PlexusDx publishes every month-to-month and prepaid tier before intake and charges the same price at every dose. MEDVi requires a health questionnaire before displaying price, and the advertised first-month rate is lower than the ongoing refill rate by $120 (semaglutide injection) or $100 (tirzepatide). Customers planning beyond the first month should budget the refill rate, not the introductory figure.

First-year cost advantage

MEDVi's introductory discount reduces the first-year total by $120 (semaglutide) or $100 (tirzepatide) compared to paying the refill rate for 12 months. That advantage disappears in month two and does not recur in subsequent years. Over 12 months, PlexusDx month-to-month semaglutide injection costs $1,320 less than MEDVi's ongoing refill rate, and tirzepatide injection saves the same $1,320 annually.

Support and care coordination

MEDVi includes unlimited doctor calls, free care coaching, and a free dietitian visit. PlexusDx includes a free check-in with a Doctor of Pharmacy. Both offer ongoing clinical support as part of the monthly fee. Customers who value dedicated dietitian access or prefer unlimited provider calls may find MEDVi's included services align with their needs, while those who prioritize pharmacy expertise may prefer PlexusDx's pharmacist check-in model.

Route flexibility

MEDVi offers both injection and oral routes for semaglutide and tirzepatide. The semaglutide oral tablet carries a $70 monthly surcharge above the injection price; tirzepatide oral and injection are advertised at the same rate. PlexusDx offers injection and oral routes for both molecules, with semaglutide oral priced at $289 month-to-month and tirzepatide oral at $349 month-to-month. Customers who prefer the oral route should compare the all-in cost for that specific form.

Choose MEDVi if…

You want access to FDA-approved branded Wegovy or Zepbound through insurance or a structured membership, and you are comfortable confirming the final medication price at checkout. You value unlimited provider calls and dedicated dietitian support bundled into the monthly fee. You prefer to complete a health questionnaire before seeing pricing. You are willing to pay a higher ongoing rate in exchange for the first-month discount and the included care-coordination services.

Choose PlexusDx if…

You want the lowest month-to-month price on compounded semaglutide or tirzepatide injection, with no introductory tier and no price change when dose increases. You prefer to see every pricing option—month-to-month, 3-month, and 6-month—published before intake. You value a free pharmacist check-in and transparent, predictable costs over the long term. You are optimizing for annual savings and do not need access to branded drugs.

Methodology and freshness

All MEDVi pricing was verified at checkout by PlexusDx (Jay Hastings) on September 4, 2026. Compounded semaglutide and tirzepatide introductory and refill rates, included services, cancellation terms, and oral-tablet surcharges were captured during a complete checkout review. The branded Wegovy and Zepbound membership structure was documented, but the final medication cost was not disclosed at checkout. PlexusDx pricing reflects published month-to-month and prepaid rates current as of September 4, 2026. All 12-month cost projections are our calculation, using each provider's standard ongoing rate and the documented introductory discount where applicable. We cite the source and capture date for every price. When evidence is incomplete—such as MEDVi's branded-pathway medication cost—we state the limitation plainly and recommend confirming at checkout.

Frequently Asked Questions

Does MEDVi charge a membership fee for compounded semaglutide or tirzepatide?

No. MEDVi's compounded plans bundle the provider visit, medication, unlimited support, and shipping into the single monthly medication price. The $99 membership applies only to the branded Wegovy and Zepbound pathway, where medication is billed separately.

What is MEDVi's real monthly cost after the first-month discount ends?

Compounded semaglutide injection refills at $299 per month, semaglutide oral tablet refills at $369 per month, and tirzepatide refills at $399 per month. The advertised first-month rates ($179, $249, and $279 respectively) apply only to the initial fill.

How much does PlexusDx save compared to MEDVi over one year?

At month-to-month rates, PlexusDx semaglutide injection saves $1,320 per year ($2,268 vs. MEDVi's $3,588), and tirzepatide injection saves $1,320 per year ($3,468 vs. MEDVi's $4,788). These are our calculations using each provider's ongoing standard rate over 12 months.

Can I get branded Wegovy or Zepbound through PlexusDx?

No. PlexusDx offers only compounded GLP-1 medications through licensed 503A compounding pharmacies. MEDVi offers a branded pathway with a $99 monthly membership; medication cost is billed separately and was not disclosed at checkout in our review.

Do MEDVi or PlexusDx raise the price when my dose increases?

No. Both MEDVi and PlexusDx charge the same monthly price at every dose level. MEDVi states dose increases do not raise the price, and PlexusDx publishes the same policy for all dose tiers.

Sources

• MEDVi compounded semaglutide and tirzepatide pricing, checkout verification by PlexusDx (Jay Hastings), captured September 4, 2026
• MEDVi branded Wegovy and Zepbound membership structure, checkout verification by PlexusDx (Jay Hastings), captured September 4, 2026
• MEDVi support inclusions and cancellation terms, checkout review, captured September 4, 2026
• MEDVi prepaid bundles, financing, and refund policy, provider website, accessed July 20, 2026
• PlexusDx pricing and support features, internal product data, current as of September 4, 2026
• PlexusDx Trustpilot rating (4.2 stars, 76% five-star, 81% four stars or higher), captured September 4, 2026

Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.