Last updated: September 22, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance.

This article is part of the PlexusDx Education Hub — evidence-based guidance on GLP-1 therapies and weight-management care. Browse all Peptides & GLP-1 education

Editorial note: PlexusDx publishes this editorial review and offers one of the programs discussed. PlexusDx is not affiliated with MEDVi and has no commercial relationship with the companies named in this article; there are no affiliate links. Information is based on the sources and dates shown.

It depends on the plan. On MEDVi's compounded semaglutide and tirzepatide programs there is no separate membership fee: MEDVi states "No membership or hidden fees" and "Medication is included in the cost of the MEDVi Program," as read September 22, 2026. The recurring charge is the whole program: $179 for the first month for new patients, then $299 per billing cycle at refill for semaglutide injection, as displayed September 22, 2026. On MEDVi's branded Wegovy® and Zepbound® pathway the answer is yes: a separate $99 monthly membership plus the medication cost (as listed on MEDVi’s program page, September 22, 2026). Both renew until you cancel.

The short answer by plan type

MEDVi uses the word "membership" in two ways on the same site, which is why answers online contradict each other. On the compounded programs, "no membership" means the recurring charge already contains the clinical service and the medication; there is no second line item. On the branded pathway, "membership" is a standing monthly fee for the service, and the FDA-approved medication is a separate cost that MEDVi says is subject to change (MEDVi's program page, read September 22, 2026).

PlexusDx publishes this comparison and offers one of the programs discussed. Information is based on the sources and dates shown.

MEDVi plan Separate membership fee? Recurring charge as of September 22, 2026 What it covers Checked
Compounded semaglutide injection No $179 first month (new patients); $299 per cycle refill / recurring, as displayed Physician review, plan, 1:1 guidance, metabolic report, medication, shipping, dietitian visits, 24/7 support September 22, 2026
Compounded tirzepatide injection No $399 per cycle, ongoing month-to-month rate, verified September 22, 2026; first-month offer shown after the questionnaire (not published) Same program benefits, per MEDVi September 22, 2026
Compounded GLP-1 tablets No About $70 per cycle over MEDVi's injection rate for the same compound (read on its plan-selection screen); no tablet total published Same program benefits, per MEDVi September 22, 2026
Branded Wegovy® pill / Wegovy® injection / Zepbound® injection Yes — separate monthly membership (amount shown on MEDVi's page) Membership plus medication cost billed separately; availability "subject to change" Membership covers the clinical service; medication is extra September 22, 2026
PlexusDx GLP-1 programs (for comparison) No ("No membership. No membership fee.") Semaglutide Injection $189/mo; Tirzepatide Injection $289/mo, month-to-month Provider visit, prescription, medication, shipping September 22, 2026

Checked September 22, 2026. MEDVi's refill rates are its ongoing month-to-month rates, verified September 22, 2026; confirm the tirzepatide first-month offer in MEDVi's official offer.

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PlexusDx Weight Management Protocols: compounded semaglutide injection from $189/mo and tirzepatide injection from $289/mo month-to-month, all-inclusive (provider visit, prescription, medication, shipping). No membership fee. Flat price at every dose.

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Included care versus a separate membership

On a medication-inclusive plan, the price is the program. MEDVi lists physician review, a personalized plan, 1:1 guidance, a metabolic report, "Free dietician visits & care coaching," "Unlimited 24/7 support," "Fast, Free Shipping" and HSA/FSA eligibility inside its compounded program price. Prescriptions are issued by licensed providers in MEDVi's network, and medication is dispensed by the compounding pharmacies MEDVi names: Triad Rx, RedRock Pharmacy and Beaker Pharmacy & Compounding.

On the branded pathway, the membership buys the service and the medication is a separate transaction at the branded product's cost. That structure is common across telehealth: Hims, Hers and Ro each charge a $149/mo recurring membership billed separately from branded medication as of September 22, 2026. The point for a MEDVi shopper is not which company's membership is cheaper but that a membership-plus-medication bill has two moving parts, and the medication part is the larger and less predictable one. For MEDVi's branded figures see MEDVi Wegovy and Zepbound Costs: Membership Plus Medication.

One regulatory distinction sits under the billing one. The compounded programs dispense compounded semaglutide or tirzepatide, prepared by state-licensed compounding pharmacies; these are not FDA-approved drug products and are not the same as Wegovy®, Ozempic®, Zepbound® or Mounjaro® (FDA statement on unapproved GLP-1 drugs). The branded pathway dispenses the FDA-approved products. A compounded GLP-1 tablet is not the FDA-approved oral product either.

Examples of a full bill without mixing plan types

Each example stays inside one plan type, because adding a compounded program price to a branded membership produces a number nobody pays.

Example 1: compounded semaglutide injection, new patient, three billing cycles. Cycle one is $179. Cycles two and three are $299 each at the displayed refill rate. The three-cycle total is $777, with no membership line. Six cycles come to $1,674 and twelve to $3,468. MEDVi does not publish its cycle length, so twelve cycles are not necessarily a calendar year. Assumption: first-month rate plus (cycles − 1) × refill rate.

Example 2: compounded tirzepatide injection. The structure is the same, first payment then refill rate, and there is no membership fee. MEDVi's ongoing month-to-month rate for compounded tirzepatide injection is $399, verified September 22, 2026. Refill only, three cycles come to $1,197, six to $2,394 and twelve to $4,788. MEDVi shows its tirzepatide first-month offer after the questionnaire; confirm it in the official offer; no new-patient tirzepatide total is computed here. Assumption: refill-only totals are cycles × the ongoing rate.

Example 3: branded Wegovy® or Zepbound®. The bill is the monthly membership shown on MEDVi's page plus the medication cost, billed separately each time it is dispensed. MEDVi's public page does not publish the medication cost, so a three-cycle total cannot be computed here. Ask MEDVi for both numbers in writing before enrolling.

For comparison: PlexusDx Semaglutide Injection, three months month-to-month. $189 × 3 = $567, one price covering the provider visit, prescription, medication and shipping, with no membership fee, flat at every dose level, and $0 charged until your provider approves the prescription. Tirzepatide Injection is $289/mo, or $867 for three months, versus MEDVi's ongoing $399/mo, $110 a month less at PlexusDx. Detailed term arithmetic for every plan lives in MEDVi Cost: Semaglutide, Tirzepatide, Membership, and Plan Prices and in MEDVi vs PlexusDx: Compare GLP-1 Prices, Plans, and Support.

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Renewal, cancellation, and medication charges

"No membership fee" does not mean "no recurring charge." MEDVi's compounded programs bill as a subscription that renews each cycle until cancelled; the refill rate is the recurring charge, and it is the number to budget around. MEDVi's policy sets the rules (MEDVi cancellation and refund policy, read September 22, 2026):

  • Cancel anytime, but the request must reach MEDVi at least 72 hours before your next billing date, by email to hello@medvi.org or through the patient-portal chat. Service continues to the end of the paid cycle.
  • No refund is issued for the month in which you cancel on monthly billing. A full refund applies only if you cancel within the first 72 hours without receiving services, or if a provider medically disqualifies you.
  • MEDVi offers 3-, 6- and 12-month bundles; their rates appear in its signup flow and are not published here; they are refundable only for months in which no medication has shipped. Consultation fees are non-refundable, and prescription medication cannot be returned.
  • On the branded pathway, the medication charge is a separate transaction from the membership; ask how each is billed and cancelled, because stopping one does not necessarily stop the other.

The step-by-step account guide is MEDVi Subscription: Billing, Cancellation, Pauses, and Refunds. For contrast, PlexusDx month-to-month plans can be cancelled anytime with no fees; the payment schedule and any refund terms for a 3- or 6-month commitment are shown at checkout.

Questions to ask before paying

  • Which plan type am I enrolling in, compounded or branded, and is there a separate membership line on the invoice?
  • What is the recurring charge after the first cycle for my medication and route? MEDVi shows its tirzepatide first-month offer after the questionnaire; confirm it in the official offer. MEDVi's tablet runs about $70 a month over its injection rate for the same compound, with no tablet total published.
  • How long is one billing cycle, and on what date does the next charge post?
  • If I am on the branded pathway, what is the medication cost per fill, and does it change with the strength my provider prescribes?
  • What is refunded if my provider does not approve a prescription, if I cancel mid-cycle, or if I choose a multi-month plan and stop early?
  • Does the price change if my provider moves me to a different medication or route?

Whatever the billing structure, whether a GLP-1 medication is appropriate for you, and how it is used, is decided by your prescribing clinician.

A note on genetics (optional)

PlexusDx offers compounded semaglutide and tirzepatide through its Weight Management Protocols. Separately, and only if it interests you, the GLP-1 & Peptide Pathways Genetic Test ($298) analyzes 14 pathways, 49 peptides, 150+ genetic insights, including variants in FTO, MC4R and TCF7L2 that relate to appetite and glucose-handling pathways. It does not predict how you will respond to any medication and does not tell you which drug, dose or provider is right for you; it is context for a conversation with your clinician. Test before you invest, and treat genetics as a guide, not a guarantee.

This article is educational. PlexusDx is not affiliated with MEDVi and has no commercial relationship with the companies discussed. PlexusDx offers compounded semaglutide and tirzepatide through its own Weight Management Protocols; this article compares approaches in the GLP-1 telehealth space. The GLP-1 & Peptide Pathways Genetic Test analyzes how your genes influence peptide-related biological pathways. It does not predict response to any specific medication and does not recommend, prescribe, or determine which peptides you should use. Consult a qualified healthcare provider before beginning any peptide protocol. Compounded semaglutide and tirzepatide are not FDA-approved drug products; they are prepared by state-licensed compounding pharmacies under federal compounding rules and are not the same as Wegovy®, Ozempic®, Zepbound® or Mounjaro®. Zepbound® and Mounjaro® are registered trademarks of Eli Lilly and Company; Wegovy® and Ozempic® are registered trademarks of Novo Nordisk A/S. PlexusDx is not affiliated with or endorsed by either company.

Frequently Asked Questions

Does MEDVi charge a membership fee?

Not on its compounded semaglutide and tirzepatide programs. MEDVi states "No membership or hidden fees" and that medication is included in the program cost, so the recurring charge is the whole program. Its branded Wegovy and Zepbound pathway does carry a separate monthly membership, with the medication cost billed on top. Check which plan type you are enrolling in.

What is MEDVi's recurring charge on the compounded plan?

For compounded semaglutide injection, $179 for the first month for new patients, then $299 per billing cycle at refill, as displayed September 22, 2026, with medication included and no membership line. For compounded tirzepatide injection, MEDVi's ongoing month-to-month rate is $399, verified September 22, 2026; its tirzepatide first-month offer is shown after the questionnaire, so confirm it in the official offer. MEDVi's tablet runs about $70 a month over its injection rate for the same compound; no tablet total is published. MEDVi does not publish its billing-cycle length.

If there is no membership fee, why am I billed every month?

Because the compounded program is a subscription. The refill rate is the recurring charge, renewing each cycle until you cancel with at least 72 hours' notice before the next billing date. "No membership fee" means there is no separate service line on top of the medication, not that billing stops. Budget around the refill rate.

How does the branded pathway bill differently?

MEDVi's branded Wegovy or Zepbound pathway charges a separate monthly membership for the service, and the FDA-approved medication is billed separately at its own cost, which MEDVi says is subject to change. The medication cost is not published on the public page, so ask MEDVi for both numbers in writing before you enroll.

Does PlexusDx have a membership fee?

No. PlexusDx states "No membership. No membership fee." One monthly price covers the provider visit, prescription, medication and shipping: Semaglutide Injection $189/mo and Tirzepatide Injection $289/mo month-to-month, flat at every dose level. You pay $0 until your provider approves your prescription, and a month-to-month plan can be cancelled anytime with no fees.

Sources and dates checked

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This article is part of the PlexusDx Education Hub. Browse all Peptides & GLP-1 education

Medical and Editorial Standards

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. Sources and the dates they were checked are listed at the end of the article.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services, and offers compounded GLP-1 programs through its Weight Management Protocols. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

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