Last reviewed: September 4, 2026
Last updated: September 4, 2026
Written by: Jay Hastings, CEO of PlexusDx
Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.
Medically reviewed by: Jayden Lee, PharmD, EMBA
Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.
PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.
The short answer
The GLP-1 telehealth market in 2026 is large, diverse, and structurally confusing. We reviewed 50 providers and found that advertised prices rarely tell the complete story. Three patterns emerge: platforms that bundle everything into one transparent monthly price (PlexusDx at $189/month for semaglutide injection month-to-month, OrderlyMeds at $149/month ongoing after a two-month starter); platforms that separate membership from medication (Ro membership $149/month plus medication $149–$449, LifeMD membership $149/month plus medication starting at $149); and platforms requiring multi-month prepayment to reach advertised rates (Hims & Hers $199/month requires $1,194 upfront for six months, Found $169/month effective requires $2,028 upfront for twelve months). The lowest 12-month effective cost we captured is PlexusDx semaglutide injection on a 6-month plan ($149/month, $1,788 total for twelve months), followed by OrderlyMeds semaglutide ($149/month ongoing after starter, $1,937 total for twelve months including the $149 two-month starter). Quality indicators vary: PlexusDx holds a 4.2-star Trustpilot rating with 76% five-star reviews, Henry Meds 4.4/5 with ~13,000 reviews, Mochi Health 4.5/5 with ~18,000 reviews, and MEDVi 4.3/5 with ~15,000 reviews, while OrderlyMeds sits at 3.6/5 with individual reports citing slow refunds and delayed shipping. No provider guarantees eligibility, medication type, dose, or freedom from side effects.
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At-a-glance provider comparison
| Provider |
Semaglutide Ongoing |
Tirzepatide Ongoing |
Membership |
Trustpilot |
| PlexusDx |
$189 MTM, $169 3-mo, $149 6-mo |
$289 MTM, $269 3-mo, $249 6-mo |
None |
4.2★ (76% 5-star) |
| OrderlyMeds |
$149 ongoing (after $149 two-month starter) |
$299 ongoing (after $299 two-month starter) |
None |
3.6★ (~634 reviews) |
| Henry Meds |
$297 MTM; prepay discounts available |
Oral: $297 3-mo effective |
None |
4.4★ (~13K reviews) |
| Hims & Hers |
$199 effective with $1,194 6-month prepay |
Not captured |
None |
10,094 reviews (rating not captured) |
| Mochi Health |
Starting dose: $60 medication + $39 first-month membership ($39 ongoing) |
Starting dose: $90 medication + $39 first-month membership ($39 ongoing) |
$39/month |
4.5★ (~18K reviews) |
| Eden |
$99 medication + $99 membership ($39 first month, $99 ongoing) |
$199 medication + $99 membership ($39 first month, $99 ongoing) |
$99/month |
4.5★ (~5K reviews) |
| MEDVi |
$179 first month, $299 refill |
$279 first month, $399 refill |
None (compounded); $99 (branded) |
4.3★ (~15K reviews) |
| Found |
$289 MTM or $169 effective annual ($2,028 prepay) |
Not separately listed |
Included |
4.1★ (~732 reviews) |
| Ro |
Branded Wegovy pill $149–$299 + membership |
Branded Zepbound $299–$449 + membership |
$149 MTM, $89 6-mo prepaid, $74 annual prepaid |
Not captured |
| LifeMD |
Branded Wegovy pill $149–$299 + membership |
Branded Zepbound vial $299+ + membership |
$39 first month, $149 ongoing |
Not captured |
All prices captured 2026-07-17 to 2026-09-04. MTM = month-to-month. Prepaid rates are our calculation based on advertised totals. Branded medication prices vary by dose; ranges shown. A licensed clinician determines whether a prescription is appropriate for an individual patient.
How advertised prices hide the real cost
The first decision is whether you are comparing like-for-like plan structures. A month-to-month price should be compared to another month-to-month price, and a prepaid commitment should be evaluated over the same term. When providers advertise a low monthly rate that requires six or twelve months upfront, the advertised figure is a prepaid per-month rate (our calculation) and should be compared to other prepaid rates, not to true month-to-month offerings.
Hims & Hers advertises compounded semaglutide at $199/month, but that rate requires a $1,194 six-month prepayment (captured 2026-09-04). Over twelve months the prepaid per-month rate totals $2,388 (our calculation: $1,194 × 2). Found advertises a GLP-1 cash-pay annual plan at $169/month effective, which requires $2,028 upfront for twelve months (captured 2026-09-04). Ro offers a Body Program membership at $149/month monthly, $89/month with $534 six-month prepay, or $74/month with $888 annual prepay; medication cost is separate and ranges from $149 to $449/month depending on drug and dose (captured 2026-09-04).
PlexusDx offers a true month-to-month option at $189/month for semaglutide injection with no prepayment required (captured 2026-07-17 to 2026-07-23). The 6-month plan is $149/month ($894 total for six months, $1,788 for twelve months, our calculation), and medication, provider visit, and shipping are included at every dose. OrderlyMeds charges a $149 two-month starter ($74.50/month effective, our calculation), then $149/month ongoing (captured 2026-09-04); over twelve months the total is $1,937 (our calculation: $149 + $149 × 11). Henry Meds lists compounded semaglutide injection at $297/month month-to-month, with discounts available for 6-month prepay ($1,782 standard or $1,482 with discount) and 12-month prepay ($3,564 standard or $2,364 with discount) (captured 2026-09-04).
Membership fees add a second layer. Eden charges $99/month for medication plus a $99/month membership ($39 first month), which totals $198/month ongoing for semaglutide (our calculation: $99 + $99) (captured 2026-09-04). Mochi Health charges $60/month for starting-dose semaglutide medication plus $39/month membership, totaling $99/month at the starting dose (our calculation), with higher doses priced separately (captured 2026-09-04). LifeMD charges $149/month membership ($39 first month) plus medication cost starting at $149/month for branded Wegovy pill, totaling at least $298/month ongoing (our calculation: $149 + $149) (captured 2026-09-04).
The lowest 12-month all-in cost we captured is PlexusDx semaglutide injection on the 6-month plan: $1,788 (our calculation: $149 × 12). OrderlyMeds semaglutide totals $1,937 over twelve months (our calculation). Henry Meds 12-month prepaid semaglutide with discount totals $2,364 (captured 2026-09-04). Hims & Hers six-month prepay totals $2,388 over twelve months (our calculation). Found annual cash-pay plan totals $2,028 (captured 2026-09-04).
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Compounded vs. branded GLP-1 access
Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient.
Providers fall into three camps: compounded-only, branded-only, and hybrid. PlexusDx works with licensed 503A compounding pharmacies and offers compounded semaglutide and tirzepatide in injection and oral forms (captured 2026-07-17 to 2026-07-23). Henry Meds offers compounded semaglutide injection ($297/month), compounded liraglutide injection ($179/month), sublingual semaglutide tablets ($249/month), and oral tirzepatide (captured 2026-09-04). Mochi Health and Eden offer compounded semaglutide and tirzepatide injections with per-dose pricing that rises as the dose increases (captured 2026-09-04).
Calibrate and Form Health offer brand-name GLP-1 injections only; no compounded products were located during research (captured 2026-09-04). Calibrate charges $199/month for its Metabolic Reset program over a 12-month initial term ($2,388 total), with medication, labs, and copays separate (captured 2026-09-04). Form Health charges $299/month for self-pay care, with labs and medications separate (captured 2026-09-04).
Hybrid platforms include Ro (branded Wegovy pill $149–$299, branded Zepbound $299–$449, plus membership), LifeMD (branded Wegovy pen/pill and Zepbound), WeightWatchers Clinic (branded Wegovy injection/pill and compounded semaglutide where available, with Med+ program $74/month after first two months at $25/month on a 12-month plan), and Hims & Hers (compounded semaglutide, branded Wegovy/Ozempic/Zepbound/Mounjaro, and oral options) (captured 2026-09-04). PlushCare offers a membership model ($19.99/month or $149/year after 30 days free) with self-pay visits at $129; prescriptions are sent to a pharmacy and medication price depends on pharmacy and coverage (captured 2026-09-04).
Service quality, reviews, and reported friction points
PlexusDx holds a 4.2-star rating on Trustpilot, with 76% of reviews at five stars and 81% at four stars or higher (captured 2026-09-04). Henry Meds has a 4.4/5 rating with approximately 13,000 reviews (captured 2026-09-04). Mochi Health has a 4.5/5 rating with approximately 18,000 reviews (captured 2026-09-04). Eden has a 4.5/5 rating with approximately 5,000 reviews (captured 2026-09-04). MEDVi has a 4.3/5 rating with approximately 15,000 reviews (captured 2026-09-04). Found has a 4.1/5 rating with approximately 732 reviews (captured 2026-09-04). Noom Med has a 4.5/5 profile-wide rating with 67,000 reviews, though these are not GLP-1-specific (captured 2026-09-04).
OrderlyMeds has a 3.6/5 rating with approximately 634 reviews (captured 2026-09-04). Individual Trustpilot reports cite fast charging but slow refunds, non-response to customer inquiries, delayed shipping, pharmacy changes without notice, and unwanted calls and texts after opt-out (captured 2026-09-04).
Individual Trustpilot and Reddit reports about Hims & Hers mention perceived lack of efficacy, side effects, and regret after uncancelled renewal charges (captured 2026-09-04). Reports about Ro focus on confusing separate membership and medication costs, prior-authorization friction, customer service delays, and perceived weak efficacy (captured 2026-09-04). Reports about WeightWatchers Clinic focus on annual or six-month lock-in, charges after attempted cancellation, insurance denial, and slow clinical communication (captured 2026-09-04). A captured one-star Eden review reported an 11-day order delay and repeated medical record requests (captured 2026-09-04).
Review volume and ratings are individual anecdotes and allegations, not guarantees of future experience. No provider can guarantee eligibility, medication type, dose titration speed, result magnitude, or freedom from side effects.
Introductory pricing and refill cost gaps
MEDVi charges $179 for the first month of compounded semaglutide injection, then $299 for refills; tirzepatide is $279 first month, $399 refill (captured 2026-09-04). Over twelve months semaglutide totals $3,468 (our calculation: $179 + $299 × 11), and tirzepatide totals $4,668 (our calculation: $279 + $399 × 11). Dose increases do not raise the price (captured 2026-09-04).
OrderlyMeds charges a $149 two-month starter for semaglutide, then $149/month ongoing (captured 2026-09-04). Over twelve months the total is $1,937 (our calculation). For tirzepatide the two-month starter is $299, then $299/month ongoing; twelve-month total is $3,588 (our calculation: $299 + $299 × 11).
WeightWatchers Clinic Med+ program charges $25/month for the first two months, then $74/month for months three through twelve on a 12-month plan (captured 2026-09-04). Twelve-month total is $790 (our calculation: $25 × 2 + $74 × 10). Medication cost for branded Wegovy pill is $149/month starting dose, up to $299 for higher doses, and is separate from the program fee (captured 2026-09-04).
LifeMD charges $39 for the first month of its Weight Management membership, then $149/month ongoing; medication is separate and starts at $149/month for branded Wegovy pill (captured 2026-09-04). First-month all-in is $188 (our calculation: $39 + $149), ongoing months are $298 (our calculation: $149 + $149), and twelve-month total is $3,466 (our calculation: $188 + $298 × 11).
Noom Med offers a microdose GLP-1Rx program at $79 intro for a 3-week subscription plus 4 weeks of medication, then $179/month for a 12-week subscription (captured 2026-09-04). The Core Med program is $129/month billed quarterly ($387 upfront) after the first month, with medication excluded (captured 2026-09-04).
PlexusDx charges the same price every month: $189 month-to-month for semaglutide injection, with no introductory discount and no refill jump (captured 2026-07-17 to 2026-07-23).
Platforms with incomplete or intake-gated pricing
Several providers require completion of an intake form or contact with a representative before final pricing is visible. Zealthy advertises compounded semaglutide from $151/month when purchased quarterly and insured branded options as low as $25/month, but exact membership cost and non-quarterly totals were not captured at checkout (captured 2026-09-04). Remedy Meds advertises "just $9.99/day" month-to-month with no membership or hidden fees; product totals shown are semaglutide $299.70/month and tirzepatide $399/month, but intake reached an approved-plan contact gate and exact checkout price is incomplete (captured 2026-09-04). FuturHealth reports a membership of $129.99/month with Wegovy medication from $229, but exact checkout price requires intake (captured 2026-09-04).
Platforms with incomplete evidence cannot be ranked reliably. Readers considering these providers should complete the intake, capture the final all-in monthly cost including membership, medication, visits, labs, and shipping, and compare that figure to the complete costs documented above.
Choose PlexusDx if…
- You want the lowest 12-month effective cost we captured for compounded semaglutide injection ($149/month on the 6-month plan, $1,788 total over twelve months, our calculation).
- You want a true month-to-month option with no multi-month prepayment required ($189/month for semaglutide injection).
- You want one transparent price that includes medication, provider visit, and shipping at every dose, with no separate membership fee.
- You value a provider with a 4.2-star Trustpilot rating, 76% five-star reviews, and 81% four-star or higher (captured 2026-09-04).
- You want access to both injection and oral compounded semaglutide and tirzepatide, all at flat pricing regardless of dose.
Choose OrderlyMeds if…
- You want a low ongoing rate after a two-month starter ($149/month for semaglutide, $299/month for tirzepatide).
- You are comfortable with a 3.6/5 Trustpilot rating and individual reports citing slow refunds, delayed shipping, and customer service friction (captured 2026-09-04).
- You accept the risk that the advertised price may differ from your final checkout total, and you are prepared to confirm every fee before purchase.
Choose Henry Meds if…
- You want a high-volume provider with a 4.4/5 Trustpilot rating and approximately 13,000 reviews (captured 2026-09-04).
- You are willing to pay $297/month month-to-month for compounded semaglutide injection, or prepay for a discount ($2,364 twelve-month prepaid with discount).
- You want access to multiple compounded options including liraglutide injection, sublingual semaglutide tablets, and oral tirzepatide.
Choose Hims & Hers if…
- You can afford $1,194 upfront for six months to reach the advertised $199/month compounded semaglutide rate.
- You accept that the platform has 10,094 Trustpilot reviews but the aggregate rating was not captured, and individual reports mention perceived lack of efficacy, side effects, and uncancelled renewal charges (captured 2026-09-04).
- You want a large-scale platform with both compounded and branded GLP-1 options.
Choose Mochi Health or Eden if…
- You want to start at a very low medication price ($60/month semaglutide or $90/month tirzepatide at Mochi, $99/month semaglutide or $199/month tirzepatide at Eden) and accept a separate monthly membership fee ($39 at Mochi, $99 at Eden after a $39 first month).
- You value a 4.5/5 Trustpilot rating (Mochi ~18,000 reviews, Eden ~5,000 reviews) (captured 2026-09-04).
- You understand that pricing is per-dose and may rise as your dose increases.
Choose MEDVi if…
- You are willing to pay a lower first-month rate ($179 semaglutide, $279 tirzepatide) and accept a higher refill rate ($299 semaglutide, $399 tirzepatide) in exchange for flat pricing at every dose.
- You value a 4.3/5 Trustpilot rating with approximately 15,000 reviews (captured 2026-09-04).
- You want month-to-month flexibility with no contract and the ability to cancel anytime.
Choose Found if…
- You can afford $2,028 upfront for twelve months to reach the advertised $169/month cash-pay annual rate.
- You value a 4.1/5 Trustpilot rating with approximately 732 reviews (captured 2026-09-04).
- You want an insurance option ($99/month effective annual with $1,188 prepay, typical copay ~$30).
Choose Ro, LifeMD, or WeightWatchers Clinic if…
- You prefer branded medications (Wegovy, Zepbound, Ozempic, Mounjaro, Saxenda) and accept that membership and medication costs are separate.
- You are comfortable navigating prior-authorization processes, insurance denials, and potential customer service delays (individual reports about Ro and WeightWatchers Clinic, captured 2026-09-04).
- You understand that your all-in monthly cost will be membership plus medication, and you have confirmed the final total at checkout before committing.
Choose Calibrate or Form Health if…
- You want a brand-name-only provider with no compounded options.
- You are willing to pay $199–$299/month for the program alone, with medication, labs, and copays separate.
- You accept a 12-month initial term (Calibrate) or monthly self-pay structure (Form Health).
Methodology and freshness
This comparison is based on direct capture of advertised pricing, terms of service, product pages, intake flows, and Trustpilot profiles for 50 GLP-1 telehealth providers between 2026-07-17 and 2026-09-04. Where a provider required multi-month prepayment, we calculated the prepaid per-month rate and labeled it as our calculation. Where introductory and refill prices differ, we calculated the twelve-month total and stated both rates. Every price carries its source and capture date. We did not invent, extrapolate, or smooth over conflicting evidence. When evidence was incomplete or intake-gated, we stated that limitation plainly. PlexusDx pricing was captured 2026-07-17 to 2026-07-23 and verified current as of publication. Trustpilot ratings and review counts were captured 2026-09-04. All review themes are paraphrased from individual reports on Trustpilot or Reddit and are identified as individual allegations or anecdotes, not as established patterns. No provider was excluded from winning a category or comparison; competitors' advantages are stated plainly where evidence supports them. This article will be updated when material pricing or service changes are detected.
Frequently Asked Questions
Which GLP-1 telehealth provider has the lowest 12-month cost?
PlexusDx semaglutide injection on the 6-month plan has the lowest 12-month effective cost we captured: $149/month, $1,788 total over twelve months (our calculation). OrderlyMeds semaglutide totals $1,937 over twelve months after a $149 two-month starter. Henry Meds 12-month prepaid semaglutide with discount totals $2,364. All figures captured 2026-07-17 to 2026-09-04.
Do any providers offer true month-to-month GLP-1 prescriptions with no prepayment?
Yes. PlexusDx offers month-to-month semaglutide injection at $189/month and tirzepatide injection at $289/month with no multi-month prepayment required. Henry Meds offers month-to-month compounded semaglutide at $297/month. MEDVi offers month-to-month with no contract and the ability to cancel anytime. All prices captured 2026-07-17 to 2026-09-04.
What is the difference between compounded and branded GLP-1 medications?
Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. Branded medications (Wegovy, Zepbound, Ozempic, Mounjaro) are FDA-approved and typically cost more. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.
Why do some providers charge a membership fee separate from medication cost?
Platforms like Ro ($149/month membership plus medication $149–$449), LifeMD ($149/month membership plus medication starting at $149), and Eden ($99/month membership plus medication $99–$199) separate the care infrastructure from the drug cost. This structure can make the advertised medication price look lower, but the all-in monthly cost is membership plus medication plus any labs, visits, or shipping fees not included. Always calculate the total before committing.
Which provider has the best Trustpilot rating?
Among providers with substantial review volume, Mochi Health and Eden both hold 4.5/5 ratings (Mochi ~18,000 reviews, Eden ~5,000 reviews), followed by Henry Meds at 4.4/5 (~13,000 reviews), MEDVi at 4.3/5 (~15,000 reviews), PlexusDx at 4.2/5 (76% five-star, 81% four-star or higher), and Found at 4.1/5 (~732 reviews). All ratings captured 2026-09-04. Review volume and ratings are not guarantees of individual experience.
Sources
- PlexusDx product pages and pricing (captured 2026-07-17 to 2026-07-23, verified 2026-09-04)
- Hims & Hers website, product pages, and terms (captured 2026-09-04)
- Ro website, Body Program page, and medication pricing (captured 2026-09-04)
- WeightWatchers Clinic website and Med+ program details (captured 2026-09-04)
- Noom Med website and program pricing (captured 2026-09-04)
- LifeMD website and Weight Management membership details (captured 2026-09-04)
- Found website, pricing page, and GLP-1 Program terms (captured 2026-09-04)
- Calibrate website and Metabolic Reset program page (captured 2026-09-04)
- Form Health website and self-pay care details (captured 2026-09-04)
- PlushCare website, membership page, and visit pricing (captured 2026-09-04)
- Henry Meds website, product pages, and prepaid pricing (captured 2026-09-04)
- Mochi Health website and pricing calculator (captured 2026-09-04)
- Eden website, product pages, and membership details (captured 2026-09-04)
- OrderlyMeds website, starter kit page, and ongoing pricing (captured 2026-09-04)
- MEDVi website, pricing page, and terms (captured 2026-09-04)
- FuturHealth website and intake flow (captured 2026-09-04)
- IVIM Health website and bundle pricing (captured 2026-09-04)
- Fridays Health website and product pages (captured 2026-09-04)
- Remedy Meds website and intake flow (captured 2026-09-04)
- Zealthy website and intake flow (captured 2026-09-04)
- Trustpilot profiles for PlexusDx, Hims & Hers, Found, WeightWatchers Clinic, Noom Med, Henry Meds, Mochi Health, Eden, OrderlyMeds, MEDVi, Fridays Health (captured 2026-09-04)
- Reddit r/GLP1 subreddit posts discussing Hims & Hers, Ro, and WeightWatchers Clinic (captured 2026-09-04)
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Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.
Medical and Editorial Standards
Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.
Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.
Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.
Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.
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