Last reviewed: September 5, 2026
Last updated: September 22, 2026
Written by: Jay Hastings, CEO of PlexusDx
Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance.
Medically reviewed by: Jayden Lee, PharmD, EMBA
Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Director, with a PharmD and MBA specializing in pharmacogenomics and clinical product development. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.
This article is part of the PlexusDx Education Hub — evidence-based guidance on GLP-1 therapies and weight-management care. Browse all Peptides & GLP-1 education
Editorial note: PlexusDx publishes this editorial review and offers one of the programs discussed. PlexusDx is not affiliated with MEDVi and has no commercial relationship with the companies named in this article; there are no affiliate links. Information is based on the sources and dates shown.
As of September 22, 2026, MEDVi's compounded semaglutide injection is $179 for the first month (new patients) and $299 per billing cycle on refills, as displayed on its program page; its compounded tirzepatide injection is $399 per billing cycle at MEDVi's ongoing month-to-month rate, verified September 22, 2026, with the first-month offer shown after the questionnaire. AltRx advertises compounded semaglutide "starting at $89/mo" and tirzepatide "starting at $149/mo," same price at every dose, with no membership fee. AltRx does not say whether those are first-month or recurring rates. Neither charges a membership fee on compounded programs, but their refund rules differ sharply.
Current verified offers
The table shows what each provider's own pages state today. "Starting at" is reproduced as written because AltRx does not publish a recurring rate. The PlexusDx month-to-month row is included because PlexusDx publishes this comparison; commitment tiers are listed separately at the end.
PlexusDx publishes this comparison and offers one of the programs discussed. Information is based on the sources and dates shown.
| Item |
MEDVi |
AltRx |
PlexusDx (month-to-month) |
Checked |
| Semaglutide injection, first month |
$179 first month (new patients) |
Not distinguished; "starting at $89/mo" |
$189/mo from month one |
Sept 22, 2026 |
| Semaglutide injection, recurring |
$299 per billing cycle, refill / recurring, as displayed September 22, 2026 |
Unknown — recurring rate not stated separately |
$189/mo |
Sept 22, 2026 |
| Tirzepatide injection |
$399 per billing cycle, ongoing month-to-month rate, verified September 22, 2026; first-month offer shown after the questionnaire |
"Starting at $149/mo"; recurring rate not stated |
$289/mo |
Sept 22, 2026 |
| Dose pricing |
"Same fair price at every dose" |
Same price at every dose |
Flat across every dose |
Sept 22, 2026 |
| Membership fee |
None on compounded programs |
None |
None |
Sept 22, 2026 |
Sources: MEDVi's program page and AltRx's site, read September 22, 2026. MEDVi's recurring figures are its ongoing month-to-month rates, verified September 22, 2026; confirm them in its official offer. The full MEDVi breakdown is in MEDVi Cost: Semaglutide, Tirzepatide, Membership, and Plan Prices.
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PlexusDx Weight Management Protocols: compounded semaglutide injection from $189/mo and tirzepatide injection from $289/mo month-to-month, all-inclusive (provider visit, prescription, medication, shipping). No membership fee. Flat price at every dose.
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What happened after the old promotion?
An earlier version of this article recorded AltRx promotional tiers with an end date of September 5, 2026, and projected annual savings from them. That promotion has passed, and those projections are withdrawn. As of September 22, 2026, AltRx's pages show "starting at" prices with no end date and no statement of what a second cycle costs. We do not know whether the current figures are the post-promotion standard rate, a new promotion, or a first-month rate. Treat the earlier tiers as historical and confirm the current recurring price at AltRx's checkout.
Ongoing price and unknown charges
MEDVi's ongoing price for semaglutide is clear in structure: a first month for new patients, then a refill rate per billing cycle. Its billing-cycle length is not published, so do not assume twelve cycles equal a calendar year. MEDVi's ongoing month-to-month rate for compounded tirzepatide injection is $399 per billing cycle, verified September 22, 2026; its tirzepatide first-month offer is shown after the questionnaire, so confirm it in the official offer. MEDVi's oral tablet runs about $70 a month over its injection rate for the same compound (read on its plan-selection screen), and MEDVi does not publish a tablet total on its public page. MEDVi offers 3-, 6- and 12-month bundles; their rates appear in its signup flow and are not published here. Its program price includes physician review, dietitian visits, coaching, 24/7 support and shipping, and MEDVi describes it as having no membership or hidden fees.
AltRx's ongoing price is the larger unknown. "Starting at" can mean a first cycle, a lowest tier, or the standard rate; AltRx's page does not say. AltRx does state free delivery, no membership fee and coverage in all 50 states. Multi-month bundle totals and branded pricing are not published.
Same-term comparison
A same-term comparison needs a recurring rate on both sides, and only MEDVi provides one. For a new patient staying three MEDVi cycles on semaglutide, the total is $179 + 2 × $299 = $777, assuming one first-month price and refills at the displayed rate. An AltRx three-cycle total cannot be computed honestly because the recurring rate is unknown; multiplying "$89" by three would assume a fact AltRx does not state. Three PlexusDx month-to-month cycles on Semaglutide Injection are $567. For tirzepatide, three refill-only MEDVi cycles at the ongoing rate are 3 × $399 = $1,197 (no new-patient series is computed because MEDVi's tirzepatide first-month offer is not published), against $867 for three PlexusDx month-to-month cycles on Tirzepatide Injection; AltRx's tirzepatide recurring rate is not stated.
If AltRx's $89 turns out to be its recurring rate at checkout, it is well below both MEDVi's $299 refill and PlexusDx's $189/mo. If it is a first-cycle rate, the comparison depends entirely on the second-cycle figure. That is the one number to obtain before enrolling.
Cancellation and commitment
Both require cancellation at least 72 hours before the next billing date, but the refund rules differ. MEDVi allows a full refund within the first 72 hours if no services were received, or on medical disqualification; after that, the month in which you cancel is not refunded, multi-month plans are refundable only for months with no medication shipped, and prescription medication cannot be returned. AltRx states that all payments are final and non-refundable; multi-month bundles are non-refundable in whole or in part, with the sole exception of clinical ineligibility, which refunds the unused portion. Under AltRx's terms, a bundle purchased before a provider review is at risk only if you are found ineligible; a change of mind is not covered.
Decision guide
Choose MEDVi if you want a published refill rate, a bundled support package with dietitian visits and 24/7 support, and a 72-hour full-refund window. Choose AltRx if its checkout confirms that the starting-at rate is the recurring rate and you accept that payments are final. In either case, get the second-cycle price in writing; for tirzepatide, MEDVi's ongoing rate is $399 per billing cycle (verified September 22, 2026) and its first-month offer is shown after the questionnaire, so confirm that in the official offer. Publicly posted MEDVi customer reviews are worth reading for how the billing rules play out in practice. Compounded semaglutide and tirzepatide from any provider are not FDA-approved; see the FDA's statement on unapproved GLP-1 drugs.
Where PlexusDx fits
PlexusDx publishes one rate per tier with no first-month-then-refill step: Semaglutide Injection $189/mo month-to-month ($169/mo on a 3-month plan, $507 commitment total; $149/mo on a 6-month plan, $894 commitment total) and Tirzepatide Injection $289/mo month-to-month ($269/mo on a 3-month plan, $807 commitment total; $249/mo on a 6-month plan, $1,494 commitment total). All-inclusive, no membership fee, flat at every dose, $0 until your provider approves; the multi-month payment schedule is shown at checkout. See the MEDVi vs PlexusDx comparison or browse all Weight Management Protocols.
A note on genetics (optional)
PlexusDx offers compounded semaglutide and tirzepatide through its Weight Management Protocols. Separately, and only if it interests you, the GLP-1 & Peptide Pathways Genetic Test ($298) analyzes 14 pathways, 49 peptides, 150+ genetic insights, including variants in FTO, MC4R and TCF7L2 that relate to appetite and glucose-handling pathways. It does not predict how you will respond to any medication and does not tell you which drug, dose or provider is right for you; it is context for a conversation with your clinician. Test before you invest, and treat genetics as a guide, not a guarantee.
This article is educational. PlexusDx is not affiliated with MEDVi and has no commercial relationship with the companies discussed. PlexusDx offers compounded semaglutide and tirzepatide through its own Weight Management Protocols; this article compares approaches in the GLP-1 telehealth space. The GLP-1 & Peptide Pathways Genetic Test analyzes how your genes influence peptide-related biological pathways. It does not predict response to any specific medication and does not recommend, prescribe, or determine which peptides you should use. Consult a qualified healthcare provider before beginning any peptide protocol. Compounded semaglutide and tirzepatide are not FDA-approved drug products; they are prepared by state-licensed compounding pharmacies under federal compounding rules and are not the same as Wegovy®, Ozempic®, Zepbound® or Mounjaro®. Zepbound® and Mounjaro® are registered trademarks of Eli Lilly and Company; Wegovy® and Ozempic® are registered trademarks of Novo Nordisk A/S. PlexusDx is not affiliated with or endorsed by either company.
Frequently Asked Questions
Is AltRx cheaper than MEDVi?
It depends on a number AltRx does not publish. AltRx advertises semaglutide starting at $89 per month and tirzepatide starting at $149 per month as of September 22, 2026, without saying whether those are first-month or recurring rates. MEDVi's semaglutide is $179 for the first month and $299 per billing cycle on refills. Confirm AltRx's second-cycle price before comparing.
Did AltRx's summer promotion end?
The promotional tiers recorded in an earlier version of this article carried an end date of September 5, 2026, and that date has passed. As of September 22, 2026, AltRx's pages show starting-at prices with no end date. Whether they are a standard rate or a new promotion is not stated, so treat the old tiers as historical and verify at checkout.
Does either provider charge a membership fee?
No. MEDVi states there is no membership or hidden fee on its compounded programs, with medication included in the program price. AltRx states no membership fee and free delivery. MEDVi's separate branded Wegovy and Zepbound pathway does charge a membership plus medication cost, but that is a different product line from the compounded programs compared here.
How do MEDVi and AltRx refund policies differ?
Both require cancellation at least 72 hours before the next billing date. MEDVi refunds in full within the first 72 hours if no services were received or on medical disqualification, and otherwise does not refund the current month. AltRx states all payments are final and non-refundable, including multi-month bundles, with the sole exception of clinical ineligibility, which refunds the unused portion.
Does MEDVi publish a tirzepatide price?
Yes. MEDVi's ongoing month-to-month rate for compounded tirzepatide injection is $399 per billing cycle, verified September 22, 2026; MEDVi shows its tirzepatide first-month offer after the questionnaire, so confirm it in the official offer. AltRx advertises tirzepatide starting at $149 per month without stating a recurring rate. PlexusDx Tirzepatide Injection is $289 per month month-to-month, $110 a month less than MEDVi's ongoing rate. A like-for-like MEDVi-versus-AltRx tirzepatide comparison still needs AltRx's recurring rate.
Sources and dates checked
- MEDVi program page (glp1.medvi.org), read September 22, 2026
- MEDVi start page (start.medvi.org), read September 22, 2026
- MEDVi cancellation and refund policy, read September 22, 2026
- AltRx official site (altrx.com), read September 22, 2026
- FDA: concerns with unapproved GLP-1 drugs used for weight loss
- PlexusDx Semaglutide Injection product page, checked September 22, 2026
- PlexusDx Tirzepatide Injection product page, checked September 22, 2026
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This article is part of the PlexusDx Education Hub. Browse all Peptides & GLP-1 education
Medical and Editorial Standards
Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.
Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. Sources and the dates they were checked are listed at the end of the article.
Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services, and offers compounded GLP-1 programs through its Weight Management Protocols. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.
Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.
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