Last reviewed: May 12, 2026 Last updated: May 12, 2026 Written by: Jay Hastings , CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations....

Henry charges $297/month month-to-month for injectable compounded semaglutide with consultation and shipping included — comprehensive but mid-to-upper tier; its tirzepatide is an oral dissolving tablet only, sold as a 3-month supply. We compare Henry's annualized cost ($3,564/year) against PlexusDx Weight Management Protocols ($1,548–$3,468/year), explain the compounded vs FDA-approved branded medication question, and walk through dose flexibility and genetic baseline differences so you can pick the right cash-pay GLP-1 route.

TrimRx vs Ro vs PlexusDx in 2026: real annual cost math, compounded vs FDA-approved branded medication, oral pill options, safety oversight, and PlexusDx's optional genetic-baseline test. Includes a four-question decision frame and pricing across PlexusDx Microdose GLP-1, Semaglutide Injection, Tirzepatide Injection, and GLP-Squared.

MEDVi, Remedy Meds, and PlexusDx all dispense compounded semaglutide and tirzepatide — but the annualized cost, billing cadence, and clinical-oversight model differ in ways the landing pages don't show. This guide walks the real numbers, the September 2025 FDA warning-letter context, and where PlexusDx Weight Management Protocols ($129/mo to $349/mo) plus the Precision Peptide Genetic Test fit relative to both.

MEDVi vs Hims vs PlexusDx in 2026: MEDVi at $299/mo ongoing month-to-month with no contract, Hims at $199/mo gated behind a $1,194 six-month prepayment, and PlexusDx Weight Management Protocols from $129/mo with no upfront commitment and an optional Precision Peptide Genetic Test for genetic-guided GLP-1 dosing.