Last reviewed: May 12, 2026 Last updated: May 12, 2026

Written by: Jay Hastings , CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

Genital Herpes

The herpes simplex virus (HSV) causes genital herpes which remains a prevalent sexually transmitted infection (STI) affecting a large number of people worldwide. Researchers find the role of genetics in genital herpes susceptibility crucial and noteworthy. This blog post examines genetic traits related to genital herpes while also examining risk factors and symptoms alongside complications and offering practical prevention and management advice. HSV-2 mainly causes genital herpes but HSV-1 can also contribute to the condition. These viruses spread between individuals via direct skin contact during sexual intercourse. Studies demonstrate that genetic factors may affect how likely an individual is to contract genital herpes. The probability of contracting this infection is influenced by various factors which include gender differences, ethnic background, sexual behavior patterns, and immune system responses. Research findings show a moderate-quality correlation between genetic factors and susceptibility to genital herpes. Continued scientific research is essential for better understanding genetic risks related to the condition and developing enhanced preventive measures. The probability of acquiring genital herpes is greater among females and African Americans as well as those who participate in multiple sexual activities and have numerous sexual partners while previous STI history also increases risk. Genetic characteristics can increase an individual's susceptibility to infection by influencing immune function and cellular mechanisms. During an initial outbreak of genital herpes patients may experience pain or itching near the genital area along with blisters and ulcers and suffer from painful urination and flu-like symptoms. The infection leads to additional risks such as heightened vulnerability to other sexually transmitted infections and newborn transmission during childbirth plus inflammation of reproductive organs and herpetic whitlow and eye infections. Adopting safer sexual practices serves as an essential strategy to minimize the risk of genital herpes infection. Healthcare providers advise sexually active people to undergo routine screenings for early detection and treatment of infections. An understanding of genetic factors which influence genital herpes susceptibility enables individuals to take active steps toward prevention and management. Genital herpes remains a widespread sexually transmitted infection whose genetic factors affect individual infection risks. Through identification of genetic markers linked to genital herpes individuals are able to make educated choices about prevention and treatment approaches. Investigate Precision Health & Wellness tests from PlexusDx for detailed genetic information about reproductive and sexual health predispositions. Maintain control over your sexual health by actively seeking knowledge and taking preventive steps. Access Precision Health & Wellness tests and discover personalized genetic data through PlexusDx.com, Amazon, or Walmart. Learning about the genetic factors of genital herpes is essential for maintaining good health and making educated choices.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.