Last reviewed: September 10, 2026 Last updated: September 10, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

Eden advertises the lowest semaglutide medication-only rate at $99/month, but when you add its mandatory $99/month membership the all-inclusive total reaches $198/month. PlexusDx offers $149/month on a six-month plan and $189 month-to-month, both with no membership fee. Fridays Health advertises tirzepatide as low as $190/month on prepaid multi-month plans, though exact terms require checkout verification. Among providers offering true month-to-month flexibility without prepayment or separate memberships, PlexusDx semaglutide at $189 and Henry Meds liraglutide at $179 represent the field's lowest all-in recurring costs. The table below ranks ten providers by their verified or advertised monthly expense; several publish introductory rates that reset at refill, and a few require quarterly or annual prepayment to unlock floor pricing.

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At-a-glance ranking: ten cheapest GLP-1 telehealth providers

The table below presents advertised or verified monthly costs for semaglutide and tirzepatide. When an advertised price is an introductory or prepaid rate, we note that constraint in the rightmost column. All figures carry their source and capture date.

Provider Semaglutide Tirzepatide Membership Notes
Fridays Health $117/mo $190/mo None Multi-month prepay; exact terms not checkout-verified (captured 2026-09-04)
PlexusDx $149/mo (6-mo), $189 MTM $249/mo (6-mo), $289 MTM None All-inclusive, same price at every dose (captured 2026-07-23)
Zealthy $151/mo $329/mo $135/mo Quarterly purchase; total cost = medication + membership (captured 2026-09-04 and 2026-07-23)
Henry Meds $179/mo (liraglutide), $297/mo (semaglutide injection) $297/mo (oral, 3-mo prepay) None Liraglutide is another GLP-1; semaglutide injection $297 MTM; tirz oral only, prepaid (captured 2026-09-04)
MEDVi $179 first month, $299 refill $279 first month, $399 refill None (compounded path) First-month introductory rate; monthly contract, no lock-in (captured 2026-09-04)
Eden $99/mo medication + $99/mo membership = $198 total $199/mo medication + $99/mo membership = $298 total $39 first month, then $99/mo Membership mandatory; ongoing all-in cost (captured 2026-09-04)
Hims & Hers $199/mo Not advertised None for cited offer 6-month prepay ($1,194 upfront), compounded semaglutide (captured 2026-09-04)
TrimRx $199 advertised, $299 at checkout $349 advertised, $399 at checkout None Advertised and checkout rates differ; prepaid plans lower effective rate (captured 2026-07-23)
Peak Wellness $249/mo MTM $349/mo MTM None Lower rates on 6-month prepaid plans (captured 2026-07-23)
Remedy Meds $299.70/mo (calculated from $9.99/day) $399/mo advertised None advertised Daily rate advertised; intake reached approved-plan contact gate, partial verification (captured 2026-09-04)

Normalized like-for-like comparison: month-to-month plans

When you strip away introductory discounts, multi-month prepayment, and separate membership charges, true month-to-month recurring cost becomes visible. The table below compares verified month-to-month (MTM) or standard ongoing rates across providers offering flexible monthly billing. Where a provider's floor price requires prepayment, we calculate the effective monthly rate and label it as our calculation.

Provider Semaglutide MTM or Standard Rate Tirzepatide MTM or Standard Rate 12-Month Total (Sema)
PlexusDx $189/mo MTM $289/mo MTM $2,268 (our calculation)
Eden $198/mo ongoing all-in $298/mo ongoing all-in $2,376 ongoing; $2,337 year one with first-month $39 membership (our calculation)
Peak Wellness $249/mo MTM $349/mo MTM $2,988 (our calculation)
Henry Meds $297/mo injection MTM $297/mo oral, 3-mo prepay only $3,564 (our calculation)
TrimRx $299/mo checkout MTM $399/mo checkout MTM $3,588 (our calculation)
MEDVi $179 first month, $299 refill $279 first month, $399 refill $3,468 year one ($179 + 11 × $299, our calculation)
Embody $299/mo $349/mo $3,588 (our calculation)
Remedy Meds $299.70/mo (30 × $9.99/day, our calculation) $399/mo advertised $3,596.40 (our calculation)

Among true month-to-month plans with no membership, PlexusDx semaglutide at $189 delivers the lowest verified ongoing cost in this cohort. Eden's ongoing all-in rate of $198 is $9 higher but includes a mandatory membership; over twelve months that translates to a $69 difference when Eden's first-month $39 rate is factored in ($2,337 vs. $2,268, our calculation).

Effective cost over twelve months: prepaid and multi-month plans

Several providers unlock lower per-month rates when you prepay three, six, or twelve months. The table below shows those effective monthly rates and the upfront commitment required.

Provider Semaglutide Prepaid Rate Upfront Cost 12-Month Total
Fridays Health $117/mo effective (multi-month prepay, terms not verified) Unknown ~$1,404 if twelve-month (our calculation, unverified)
PlexusDx $149/mo on 6-month plan $894 per 6-month period $1,788 (our calculation)
Hims & Hers $199/mo on 6-month prepay $1,194 $2,388 (our calculation)
Found (cash-pay annual) $169/mo effective on annual prepay $2,028 $2,028
Zealthy $151/mo medication when purchased quarterly + $135/mo membership ~$453 quarterly medication + $405 quarterly membership (our calculation) ~$3,432 (our calculation)

On a six-month prepaid basis, PlexusDx semaglutide costs $1,788 over twelve months ($894 × 2, our calculation), $240 below Found's annual cash-pay total of $2,028 and $600 below Hims & Hers' six-month plan renewed twice ($2,388, our calculation). Fridays Health advertises $117/month on a multi-month plan, but because exact prepayment terms are not checkout-verified we advise confirming the total upfront charge and any refund policy before committing.

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Decision factors

Introductory rates vs. recurring cost

MEDVi advertises semaglutide at $179 for the first month, but refills cost $299 (captured 2026-09-04). Eden's membership is $39 in month one, then $99 ongoing (captured 2026-09-04). If you see an advertised rate significantly below the field average, confirm whether it applies to refills or resets after an introductory period. Over twelve months, MEDVi's structure totals $3,468 ($179 + 11 × $299, our calculation), $1,200 more than PlexusDx's month-to-month plan at $2,268.

Membership fees and all-inclusive models

Eden, Zealthy, Ro, LifeMD, Found (insurance track), Noom, and WeightWatchers Clinic charge separate memberships that cover clinical access, coaching, or program materials but may exclude medication cost. Eden's $99/month membership is mandatory even on the compounded path (captured 2026-09-04). Zealthy adds $135/month (captured 2026-07-23). PlexusDx, Henry Meds, Embody, Peak Wellness, TrimRx, Remedy Meds, and MEDVi bundle clinical care and shipping into a single monthly charge with no separate membership.

Dose-based pricing

Some providers increase the monthly rate as your dose escalates. TrimRx, Remedy Meds, and MEDVi structures may vary by dose tier; exact policies require checkout or intake confirmation. PlexusDx and Embody both guarantee the same monthly price at every dose (captured 2026-07-23), eliminating surprise cost increases during titration.

Route and medication variety

Henry Meds offers sublingual semaglutide tablets at $249/month and premium oral drops at $179/month (captured 2026-09-04), providing non-injection paths at competitive rates. PlexusDx, Eden, and Hims & Hers advertise both injectable and oral routes, with availability varying by intake approval. MEDVi charges a $70 surcharge for semaglutide tablets over injections (captured 2026-09-04). Henry Meds also supplies liraglutide injection at $179/month (captured 2026-09-04), another GLP-1 receptor agonist, though liraglutide requires daily administration rather than weekly dosing.

Prepayment, lock-in, and refund policies

Hims & Hers requires $1,194 upfront for its six-month compounded semaglutide offer (captured 2026-09-04). Found's annual cash-pay plan charges $2,028 at enrollment (captured 2026-09-04). Zealthy's advertised $151/month rate applies to quarterly purchases (captured 2026-09-04). Fridays Health's $117 and $190 figures appear tied to multi-month prepayment, but exact terms are not checkout-verified (captured 2026-09-04). WeightWatchers Clinic negative reviews report difficulty cancelling and charges persisting after attempted cancellation (captured 2026-09-04 on Trustpilot). Before prepaying, confirm the refund policy if you need to stop early; PlexusDx, MEDVi, Eden, Henry Meds, Peak Wellness, and TrimRx all operate on month-to-month contracts with no multi-month lock-in (captured 2026-07-23 and 2026-09-04).

Service reliability and customer experience

PlexusDx holds a 4.3-star rating on Trustpilot, with 79% of reviews at five stars and 83% at four stars or higher (captured 2026-09-09, trustpilot.com/review/plexusdx.com). Henry Meds reports 4.4 stars across approximately 13,000 reviews (captured 2026-09-04). Remedy Meds displays a 4.7-star rating during intake (captured 2026-09-04). Eden averages 4.5 stars from roughly 5,000 reviews, though one captured one-star report describes an 11-day order delay and repeated medical-record requests (captured 2026-09-04 on Trustpilot). Hims & Hers has over 10,000 reviews; negative themes include perceived lack of efficacy, side effects, and regret over uncancelled renewals (captured 2026-09-04 on Trustpilot). Ro negative themes include confusing separate membership and medication costs, prior-authorization friction, customer-service delays, and perceived weak efficacy (captured 2026-09-04 on Trustpilot). These are individual reports and allegations; rating averages reflect the full range of customer experience.

Choose Fridays Health if…

You are comfortable with multi-month prepayment and the $117 semaglutide or $190 tirzepatide advertised rates fit your budget. Because checkout details are not yet verified (captured 2026-09-04), confirm the exact upfront charge, refill terms, and refund policy during intake before committing.

Choose Eden if…

You prefer splitting medication and membership charges and appreciate the flexibility of starting with a $39 first-month membership fee. Over twelve months the all-inclusive ongoing cost ($198/month semaglutide, $298/month tirzepatide) is competitive, though slightly higher than PlexusDx month-to-month. Eden's 4.5-star Trustpilot rating reflects generally positive feedback, but one captured report describes order delays and repeated record requests (captured 2026-09-04).

Choose Henry Meds if…

You want oral or sublingual GLP-1 options alongside traditional injections, or you are interested in liraglutide at $179/month. Henry Meds' semaglutide injection costs $297 month-to-month (captured 2026-09-04), higher than PlexusDx, but its 4.4-star rating across 13,000 reviews and range of formulations offer flexibility.

Choose Hims & Hers if…

You can prepay $1,194 for six months and the $199/month effective rate fits your budget. Hims & Hers also provides branded and oral options (captured 2026-09-04). Negative Trustpilot themes include perceived lack of efficacy, side effects, and uncancelled renewal regret (captured 2026-09-04); weigh service-reliability reports alongside cost savings.

Choose Found if…

You prefer an integrated coaching program and can prepay $2,028 annually to lock in a $169/month effective rate for compounded medication. Found also offers an insurance track starting at $99/month effective on annual prepay (captured 2026-09-04). The 4.1-star Trustpilot rating (captured 2026-09-04) suggests mixed customer experience; read recent reviews before enrolling.

Where PlexusDx fits

PlexusDx delivers the field's lowest verified month-to-month semaglutide injection cost at $189, with no membership fee, no dose escalation surcharge, and no multi-month lock-in. On a six-month plan the rate drops to $149/month ($894 per period), for a twelve-month total of $1,788 (our calculation) - $240 below Found's $2,028 annual prepay and $600 below Hims & Hers' $2,388 six-month-renewed-twice structure (our calculation). Tirzepatide follows the same model: $289 month-to-month, $249 on six-month commitment. Every plan includes medication, licensed-provider care, and shipping in a single predictable charge. The same price applies at every dose, so titration never triggers a surprise bill increase. PlexusDx holds a 4.3-star Trustpilot rating with 79% five-star reviews and 83% at four stars or higher (captured 2026-09-09), reflecting consistent service delivery. If transparent pricing, month-to-month flexibility, and no separate membership align with your priorities, PlexusDx offers a cost and service balance that competes directly with the lowest advertised rates in the field.

Methodology and freshness

We captured advertised pricing, checkout flows, membership terms, and Trustpilot ratings between July 17 and September 9, 2026. Introductory rates, refill prices, and membership fees are drawn directly from provider websites, intake questionnaires, or checkout screens; each figure carries its source and capture date in the research packet. When a provider's floor price requires multi-month prepayment, we calculate the effective monthly rate and the twelve-month total and label both as our calculation. We publish competitor advantages where evidence supports them and state PlexusDx pricing using the same rules. No provider paid for inclusion; we are one of the ten discussed.

Frequently Asked Questions

Which provider has the absolute lowest advertised GLP-1 price?

Fridays Health advertises semaglutide at $117/month and tirzepatide at $190/month on multi-month prepaid plans (captured 2026-09-04). Exact upfront commitment and refund terms are not checkout-verified; confirm those details during intake before enrolling.

Does Eden's $99 semaglutide rate include everything?

No. Eden's $99/month covers medication only. You must also pay a mandatory $99/month membership (after a $39 first month), bringing the ongoing all-inclusive cost to $198/month (captured 2026-09-04).

How do PlexusDx prices compare month-to-month?

PlexusDx semaglutide injection costs $189 month-to-month with no membership, the lowest verified ongoing rate among providers offering true monthly flexibility. On a six-month plan the rate is $149/month, totaling $1,788 over twelve months (our calculation), below Found's $2,028 annual prepay.

Why do some providers show different prices at checkout than on their homepage?

Advertised rates may be introductory, first-month, or multi-month prepay figures. TrimRx advertises semaglutide at $199 but charges $299 at checkout (captured 2026-07-23). MEDVi's first month is $179, refills $299 (captured 2026-09-04). Always complete intake or reach checkout to see the recurring monthly charge.

Are compounded semaglutide and tirzepatide FDA-approved?

No. Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

Sources

  • PlexusDx pricing and service terms, plexusdx.com, captured 2026-07-17 through 2026-07-23
  • PlexusDx Trustpilot profile, trustpilot.com/review/plexusdx.com, captured 2026-09-09
  • Eden, Henry Meds, MEDVi, TrimRx, Peak Wellness, Embody, Zealthy, Fridays Health, Remedy Meds advertised pricing, respective provider websites and intake flows, captured 2026-07-17 through 2026-09-04
  • Found, Hims & Hers, Ro, LifeMD, WeightWatchers Clinic, Noom, Calibrate pricing and membership terms, respective provider websites, captured 2026-09-04
  • Trustpilot reviews for Eden, Henry Meds, Found, MEDVi, Fridays Health, Remedy Meds, Hims & Hers, Ro, WeightWatchers Clinic, Noom, trustpilot.com, captured 2026-09-04
  • MEDVi and Remedy Meds checkout and intake verification attempts, captured 2026-09-04

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Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

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