Last reviewed: May 12, 2026 Last updated: May 12, 2026

Written by: Jay Hastings , CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

Low Sperm Count: Understanding the Genetic Factors

Low sperm count stands as a prevalent male fertility problem which can greatly affect a couple's chances of having a child. Oligospermia refers to cases where semen contains less than the normal 15 million sperm per milliliter. Besides fertility challenges low sperm count results in psychological stress for affected individuals and may suggest the presence of deeper health problems. People who wish to combat low sperm count require an understanding of its genetic factors. The origins of male fertility problems show a genetic component in about 15% of cases. Being genetically predisposed to low sperm count does not guarantee an increased overall risk for the condition. Factors like age along with lifestyle choices including diet and smoking habits as well as exposure to toxins and obesity together with certain medications and medical conditions also contribute to the condition. Genetics influence sperm count but other risk factors must be evaluated to fully understand fertility outcomes. People who adjust their lifestyle by eating healthier foods and steering clear of substances like alcohol and tobacco while keeping their weight in check can enhance both sperm quality and count. Precision Health & Wellness tests from PlexusDx offer important information for people who are worried about their fertility and possible genetic risks. Understanding your genetic profile regarding reproductive and sexual health enables you to make educated choices about lifestyle modifications and treatment possibilities to improve fertility outcomes. Low sperm count emerges as a complex condition shaped by both genetic influences and external factors such as lifestyle habits and environmental exposures. Individuals who address genetic predispositions and modifiable risks can improve their fertility potential while progressing toward their objective of building a family. Utilize PlexusDx Precision Health & Wellness tests to receive specific reproductive health insights and implement effective strategies to enhance your fertility results.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.