Health Education Articles | PlexusDx

Man reviewing SHBG genetics and free testosterone variability — PlexusDx Precision Peptide Genetic Test

SHBG Genetics: Why Your Free Testosterone Varies

SHBG — sex hormone-binding globulin — determines how much of your testosterone is biologically available to cells. High SHBG binds more testosterone, reducing free levels; low SHBG releases more. SHBG gene variants shape your baseline level genetically. The Precision Peptide Genetic Test analyzes SHBG as part of Men’s Hormone insights across 14 pathways, 49 peptides, and 150+ genetic insights.

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