Last reviewed: September 22, 2026
Last updated: September 22, 2026
Written by: Jay Hastings, CEO of PlexusDx
Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.
Medically reviewed by: Jayden Lee, PharmD, EMBA
Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.
PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.
The short answer
ReflexMD charges $299 per month for compounded semaglutide and $399 per month for compounded tirzepatide, with provider access bundled and no separate membership fee. The company advertises no hidden costs, and our September 2026 verification confirms no documented add-ons for shipping, visits, or lab work at those standard rates. An affiliate page shows a $199 introductory rate for semaglutide, but the homepage standard rate remains $299 per month.
At standard pricing over 12 months, ReflexMD semaglutide totals $3,588 annually ($299/month); tirzepatide totals $4,788 ($399/month). PlexusDx offers compounded semaglutide injection at $189 per month ($2,268 annually) and tirzepatide injection at $289 per month ($3,468 annually)—$108 and $110 less per month respectively, with the same zero-membership structure and all-inclusive pricing.
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ReflexMD pricing at a glance
| Product |
Standard Rate |
Membership Fee |
What's Included |
| Compounded semaglutide injection |
$299/month |
$0 |
Provider access + medication |
| Compounded tirzepatide injection |
$399/month |
$0 |
Provider access + medication |
| Oral weight-control tablets |
$199/month |
$0 |
Provider access + medication |
ReflexMD pricing verified September 4, 2026, from reflexmd.com. Affiliate pages show a $199 introductory rate for semaglutide; homepage standard rate is $299/month.
Breaking down the all-in cost: medication, visits, labs, and shipping
ReflexMD's headline rates bundle provider access and medication. The evidence captured in September 2026 shows no separate line items for shipping, clinical visits, or lab work at the published monthly prices. ReflexMD advertises "no hidden costs" and no long-term contract requirement. If you see the $199 semaglutide figure on an affiliate page, confirm at checkout whether it applies to your first month only or ongoing—our verification shows a standard $299 rate on the company's homepage.
The oral tablet product lists at $199 per month. The exact active ingredient (semaglutide, tirzepatide, or another compound) was not confirmed in the evidence; verify the formulation and FDA compounding status before enrollment.
Normalized 12-month cost (standard rates, month-to-month)
| Product |
Provider |
Monthly Rate |
12-Month Total (Our Calculation) |
| Compounded semaglutide injection |
ReflexMD |
$299 |
$3,588 |
| Compounded semaglutide injection |
PlexusDx |
$189 |
$2,268 |
| Compounded tirzepatide injection |
ReflexMD |
$399 |
$4,788 |
| Compounded tirzepatide injection |
PlexusDx |
$289 |
$3,468 |
PlexusDx delivers compounded semaglutide for $108 less per month and tirzepatide for $110 less per month than ReflexMD's standard rates. Over one year, that difference amounts to $1,320 on semaglutide and $1,320 on tirzepatide (our calculation). Both providers charge zero membership fees and bundle provider access in the medication price.
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What you're actually paying for
Both ReflexMD and PlexusDx use the same all-inclusive model: one monthly charge covers your asynchronous provider consultation, prescription (if approved), compounded medication, and delivery. Neither program imposes a separate membership fee, and neither locks you into a multi-month contract at sign-up.
The pricing difference lies in the base medication rate. ReflexMD's $299 semaglutide and $399 tirzepatide rates exceed PlexusDx's $189 and $289 by $110 per month on each compound. That premium persists at every dose—neither provider charges more as your dose escalates during titration.
Affiliate pricing and advertised discounts
ReflexMD advertises a $199 introductory rate for compounded semaglutide on some affiliate pages, while the homepage lists the $299 standard rate (verified September 4, 2026). The evidence does not confirm whether the $199 figure applies only to your first month, requires prepayment, or continues month-to-month. If you see that lower rate during enrollment, confirm the terms at checkout and ask when the price steps to $299.
Assuming the $199 rate applies to month one only and standard $299 billing resumes in month two, your 12-month total would be $3,488 ($199 + $299 × 11 = $3,488, our calculation), or roughly $290.67 per month on average. That blended figure still exceeds PlexusDx's flat $189 rate by about $102 per month.
Service and reliability
ReflexMD operates a telehealth platform with asynchronous provider review, similar to PlexusDx and other compounded-GLP-1 services. Both offer messaging access to clinical staff for questions during treatment.
PlexusDx holds a 4.3-star rating on Trustpilot, with 79% of reviews at five stars and 83% at four stars or higher (captured September 9, 2026; trustpilot.com/review/plexusdx.com). The evidence packet does not include verified review data for ReflexMD, so we cannot report comparative service ratings here.
Choose ReflexMD if…
- You already have a relationship with the platform or your provider specifically recommended it.
- You qualify for the advertised $199 introductory rate and confirmed it applies beyond the first month, closing the price gap.
- You prefer the user interface or customer-support channels ReflexMD offers.
Choose PlexusDx if…
- You want the lowest verified standard rate for compounded semaglutide ($189/month) or tirzepatide ($289/month), saving $108–$110 per month compared to ReflexMD.
- You value transparent pricing with no affiliate variability—every patient sees the same published rate.
- You want a provider with a documented 4.3-star Trustpilot rating and 83% of reviews at four stars or above.
- You prefer one flat price at every dose during titration, with no risk of cost increases as your prescription advances.
Methodology and freshness
We captured ReflexMD pricing from reflexmd.com on September 4, 2026, and PlexusDx pricing on September 22, 2026. Review data for PlexusDx was captured from Trustpilot on September 9, 2026. The 12-month totals and blended averages are our calculation, derived by multiplying the verified monthly rates by twelve. ReflexMD's affiliate $199 introductory figure appears on partner pages but not the main product page; we label it as introductory and advise confirming checkout terms. No verified review volume, rating, or complaint themes for ReflexMD were available in the evidence, so we omit service-quality claims for that provider. Prices, terms, and service features may change; confirm current rates and inclusions before enrollment.
Frequently Asked Questions
Does ReflexMD charge separately for shipping, labs, or provider visits?
ReflexMD's verified pricing bundles provider access and medication in one monthly charge, with no documented separate fees for shipping, visits, or lab work as of September 4, 2026. Confirm at checkout that your total matches the advertised rate.
What is ReflexMD's $199 semaglutide rate, and does it continue every month?
The $199 figure appears on ReflexMD affiliate pages as an introductory rate, while the homepage lists $299 as the standard monthly price. The evidence does not confirm whether $199 applies only to month one or continues indefinitely. Ask during enrollment when the rate steps to $299, if at all.
How much do I save with PlexusDx over 12 months compared to ReflexMD?
At standard rates, PlexusDx semaglutide costs $2,268 annually versus ReflexMD's $3,588—a $1,320 annual saving (our calculation). PlexusDx tirzepatide costs $3,468 annually versus ReflexMD's $4,788, also saving $1,320 per year.
Are ReflexMD and PlexusDx medications FDA-approved?
No. Both providers dispense compounded medications, which are not FDA-approved. The FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient.
Can I cancel either program at any time, or am I locked into a contract?
ReflexMD advertises no long-term contract requirement, and PlexusDx operates month-to-month with no multi-month commitment. Confirm cancellation policies and any notice requirements with the provider before your first order.
Sources
- PlexusDx Weight Management Protocols – plexusdx.com/collections/weight-management-protocols (accessed September 22, 2026)
- ReflexMD pricing and affiliate pages – reflexmd.com (accessed September 4, 2026)
- PlexusDx Trustpilot profile – trustpilot.com/review/plexusdx.com (accessed September 9, 2026)
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Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.
Medical and Editorial Standards
Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.
Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.
Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.
Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.
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