Last reviewed: September 22, 2026 Last updated: September 22, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

Pomegranate Health advertises compounded semaglutide injection at $119/month and compounded tirzepatide injection (with B6 starter) at $149/month, billed monthly, with no stated membership fee (captured September 4, 2026 from joinpomegranate.com/products/compounded-semaglutide and app.joinpomegranate.com/pricing). These figures represent the lowest advertised or starter rates; dose tiers exist in the app and higher doses may carry different pricing. The capture notes that historical materials mention a consult deposit but the current product page claims no extra fees—readers should confirm the final checkout total and the rate for their specific prescribed dose. Over 12 months at the advertised starter rates, Pomegranate's semaglutide totals $1,428 and tirzepatide totals $1,788 (our calculation), compared to PlexusDx month-to-month semaglutide at $2,268 and tirzepatide at $3,468 (same price at every dose). Pomegranate's advertised starter rates are $70/month lower for semaglutide and $140/month lower for tirzepatide, assuming no additional fees and that the starter rate applies to your prescribed dose.

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At-a-glance: Pomegranate Health vs PlexusDx cash-pay GLP-1

Item Pomegranate Health PlexusDx
Semaglutide injection (MTM) $119/mo (starter rate, dose tiers in app) $189/mo (same at every dose)
Tirzepatide injection (MTM) $149/mo (starter rate, dose tiers in app) $289/mo (same at every dose)
Membership / service fee $0 (product page; historical mention of consult deposit—confirm at checkout) $0
12-month total, semaglutide (MTM) $1,428 (our calculation, starter rate) $2,268 (our calculation)
12-month total, tirzepatide (MTM) $1,788 (our calculation, starter rate) $3,468 (our calculation)
Medication type Compounded injection with additives (not FDA-approved) Compounded injection (not FDA-approved)
Evidence status Primary-conflict; checkout verification pending Direct

Pomegranate Health data captured September 4, 2026 from joinpomegranate.com/products/compounded-semaglutide and app.joinpomegranate.com/pricing. PlexusDx data captured July 17–23, 2026.

Pomegranate Health cash-pay pricing breakdown

Pomegranate Health's product page lists compounded semaglutide injection at $119/month and compounded tirzepatide injection (with B6 starter) at $149/month, both billed monthly with a one-month supply. The page states no membership or extra fee. However, the evidence carries a "Primary-conflict" flag: historical materials mention a consult deposit, but the current product page claims no extra fee. The capture note advises readers to confirm the final checkout total before purchase. We present the advertised figures with that caveat.

The $119 semaglutide and $149 tirzepatide rates are labeled as starter or lowest advertised rates. Dose tiers exist within the Pomegranate app, meaning higher doses may carry different monthly pricing. The research packet notes "Verify full dose ladder in app." If your provider prescribes a higher maintenance dose, confirm the rate for that specific tier—the advertised starter rate may not apply throughout your treatment.

What is included in the monthly rate

Based on the product page (captured September 4, 2026), the monthly rate covers compounded semaglutide or tirzepatide injection medication and shipping. The product page claims no membership fee. Provider consultations and dose adjustments are presumably included, though the historical mention of a consult deposit creates uncertainty. Readers should verify at checkout whether any one-time or recurring consultation fees apply and confirm that the starter rate covers their prescribed dose.

12-month cost at Pomegranate's advertised starter rates

  • Semaglutide: $119/month × 12 = $1,428 over one year (our calculation, assuming starter rate applies).
  • Tirzepatide: $149/month × 12 = $1,788 over one year (our calculation, assuming starter rate applies).

These totals assume the starter rate holds for 12 months and no additional fees appear. If your dose escalates into a higher pricing tier or if a consultation deposit or other fee is charged, your effective cost will be higher.

PlexusDx cash-pay pricing breakdown

PlexusDx charges $189/month for compounded semaglutide injection and $289/month for compounded tirzepatide injection, month-to-month with no membership fee (captured July 17–23, 2026). The rate is the same at every dose—starter, maintenance, or maximum—so your monthly cost does not change as your provider adjusts your prescription.

What is included in the PlexusDx monthly rate

The monthly rate covers your online provider visit, prescription, compounded medication, and shipping. There are no separate consultation fees, membership dues, or upfront commitments. A licensed provider reviews your intake and medical history to determine whether a GLP-1 prescription is appropriate; no charge is applied until the provider approves your prescription.

12-month cost at PlexusDx

  • Semaglutide injection: $189/month × 12 = $2,268 over one year (our calculation).
  • Tirzepatide injection: $289/month × 12 = $3,468 over one year (our calculation).

These totals reflect the published month-to-month rate with no prepayment or multi-month discount. PlexusDx also offers three-month and six-month prepaid plans at lower per-month rates, but the like-for-like comparison here uses month-to-month billing to match Pomegranate's structure.

Like-for-like comparison: Pomegranate vs PlexusDx month-to-month

Provider Semaglutide (MTM) Tirzepatide (MTM) 12-mo Sema 12-mo Tirz
Pomegranate Health (starter rate) $119/mo $149/mo $1,428 $1,788
PlexusDx (all doses) $189/mo $289/mo $2,268 $3,468
Difference PlexusDx +$70/mo PlexusDx +$140/mo PlexusDx +$840/yr PlexusDx +$1,680/yr

All figures our calculation based on advertised rates. Pomegranate totals assume the starter rate applies for 12 months and no additional fees; dose-tier pricing may differ. PlexusDx totals reflect the published month-to-month rate, same at every dose.

Pomegranate Health's advertised starter rates are $70/month lower for semaglutide and $140/month lower for tirzepatide, translating to $840/year and $1,680/year savings respectively (our calculation). However, these savings assume the starter rate applies to your prescribed dose throughout treatment and that no consultation deposit or other fees appear at checkout. PlexusDx's higher rates hold constant across all dose levels, so the cost remains predictable as your provider adjusts your prescription.

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Decision factors: What to verify before choosing Pomegranate Health

Checkout confirmation

The evidence status for Pomegranate Health is "Primary-conflict," meaning the advertised pricing conflicts with historical references to a consult deposit. The product page (captured September 4, 2026) states no membership or extra fee, but the capture note advises confirming the current checkout flow. Before committing, verify the final total at checkout, including any one-time consultation charges, deposit requirements, or shipping fees not listed on the product page.

Dose-ladder pricing transparency

The $119 semaglutide and $149 tirzepatide figures are starter rates. The research packet notes "dose tiers in app" and advises readers to "verify full dose ladder in app." If your provider prescribes a higher dose during titration or maintenance, confirm the rate for that tier. A lack of published dose-ladder pricing means you may encounter a rate increase mid-treatment that is not reflected in the advertised starter figures.

Service and support structure

Pomegranate Health focuses on reproductive and metabolic health for women, offering menopause care, hormone therapy, and GLP-1 weight management. The platform's service model—whether ongoing provider messaging, dose-adjustment consultations, or side-effect support are included or incur separate fees—is not detailed in the captured pricing evidence. Ask during intake or checkout what level of provider access and follow-up is included in the monthly rate.

Decision factors: What PlexusDx offers

Same rate at every dose

PlexusDx charges $189/month for semaglutide and $289/month for tirzepatide regardless of dose. Whether your provider prescribes a starter, maintenance, or maximum dose, your monthly cost remains the same. This removes the uncertainty that comes with dose-tier pricing and makes budgeting straightforward over a long treatment arc.

All-inclusive monthly rate

The monthly rate covers your provider visit, prescription, medication, and shipping with no separate consultation fees, membership dues, or upfront commitments. A licensed provider reviews your intake and medical history; if approved, your prescription ships with no additional charges. Ongoing dose adjustments and provider messaging are included.

Verified review record

PlexusDx holds a 4.3-star rating on Trustpilot, with 79% of reviews at five stars and 83% at four stars or higher (captured September 9, 2026; trustpilot.com/review/plexusdx.com). This verified review profile offers a transparent window into service quality, support responsiveness, and patient experience.

Choose Pomegranate Health if…

  • You confirm at checkout that the advertised $119 semaglutide or $149 tirzepatide starter rate applies to your prescribed dose and that no additional fees are charged.
  • You verify the dose-ladder pricing in the app and are comfortable with the possibility of rate increases as your dose escalates.
  • You prefer a platform that integrates GLP-1 weight management with broader women's metabolic and reproductive health services.
  • You value the lowest advertised starter rate and are willing to accept the evidence gaps (checkout verification pending, dose-tier pricing incomplete) documented in this comparison.

Choose PlexusDx if…

  • You want a single monthly rate that holds at every dose—no hidden tiers, no rate surprises as your provider adjusts your prescription.
  • You value transparent, all-inclusive pricing with no membership fees, consultation charges, or upfront commitments.
  • You prefer a verified review record (4.3 stars on Trustpilot, 79% five-star) that documents service quality and support responsiveness.
  • You are comfortable paying $70/month more for semaglutide or $140/month more for tirzepatide in exchange for dose-agnostic pricing, straightforward evidence, and an established review profile.

Methodology and freshness

Pomegranate Health pricing, fee structure, and medication details were captured September 4, 2026 from joinpomegranate.com/products/compounded-semaglutide and app.joinpomegranate.com/pricing. Evidence status is "Primary-conflict"; the product page states no membership or extra fee, but historical materials mention a consult deposit. The capture note advises readers to confirm current checkout totals. Dose-tier pricing exists in the app but specific higher-dose rates are not provided; readers should verify the rate for their prescribed dose. PlexusDx pricing was captured July 17–23, 2026 from live product pages. PlexusDx review data were captured September 9, 2026 from trustpilot.com/review/plexusdx.com. All 12-month cost totals and effective monthly rates are our calculation based on the advertised rates. This article was published September 22, 2026.

Frequently Asked Questions

Does Pomegranate Health require insurance for GLP-1 prescriptions?

No. Pomegranate Health offers cash-pay compounded semaglutide at an advertised $119/month and tirzepatide at $149/month with monthly billing, no insurance required. Confirm at checkout whether additional fees apply and verify the rate for your prescribed dose.

Is the $119 Pomegranate semaglutide rate the same at every dose?

No. The $119 figure is the advertised starter or lowest rate; dose tiers exist in the app and higher doses may carry different monthly pricing. Verify the rate for your specific prescribed dose before committing to treatment.

Does PlexusDx charge more as my GLP-1 dose increases?

No. PlexusDx charges $189/month for semaglutide and $289/month for tirzepatide regardless of dose. Whether your provider prescribes a starter, maintenance, or maximum dose, your monthly cost remains the same.

Are Pomegranate's compounded GLP-1 medications FDA-approved?

No. Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient.

How much do I save with Pomegranate Health over PlexusDx?

At the advertised starter rates, Pomegranate is $70/month lower for semaglutide ($840/year) and $140/month lower for tirzepatide ($1,680/year), our calculation. Savings assume the starter rate applies to your prescribed dose and no additional fees appear at checkout.

Sources

  • Pomegranate Health product page: joinpomegranate.com/products/compounded-semaglutide (accessed September 4, 2026)
  • Pomegranate Health app pricing: app.joinpomegranate.com/pricing (accessed September 4, 2026)
  • PlexusDx product pages (accessed July 17–23, 2026)
  • PlexusDx Trustpilot profile: trustpilot.com/review/plexusdx.com (accessed September 9, 2026)

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Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

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