Last reviewed: May 12, 2026
Last updated: May 12, 2026
Written by:
Jay Hastings
,
CEO of PlexusDx
Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.
Medically reviewed by:
Jayden Lee, PharmD, EMBA
Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.
This article is part of the PlexusDx Education Hub — evidence-based guidance on GLP-1 therapies, weight management protocols, and the genetic variables behind every metabolic decision. Browse all Peptides & GLP-1 education
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What follows is an independent editorial review from PlexusDx. No commercial relationship with Medvi exists, no affiliate links are used, and no compensation is involved.
A weight-loss program is more than a medication — it is a provider model, an eligibility screen, and a delivery system. This review looks at Medvi’s weight-loss offering as a whole: the compounds it uses, how care is delivered, what it costs, and the individual variable that explains why two people on the same plan can differ. Fair-balance framing, current as of April 2026.
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Medvi’s weight-loss program in brief
Medvi operates as a telehealth and compounded-pharmacy program. A licensed provider reviews a virtual intake and, where appropriate, prescribes through a licensed 503A pharmacy. As verified July 2026, the weight-loss menu is compounded semaglutide injection, compounded tirzepatide injection, and a once-daily dissolvable GLP-1 tablet, alongside branded Wegovy and Zepbound through a separate membership. See Medvi’s official website for current details.
The medication options for weight loss
Two compound families anchor the program. Semaglutide is a GLP-1 receptor agonist; tirzepatide is a GIP/GLP-1 dual agonist that engages two incretin receptors. Both are offered as compounded injections, with a dissolvable GLP-1 tablet as an oral alternative and branded Wegovy and Zepbound on a separate track. The compounded options are not FDA-approved brand products — a distinction to weigh when choosing.
The clinical touchpoints along the way
Care follows a repeatable arc: an intake covering weight, medical history, and current medications; clinician review and, if eligible, a prescription; fulfillment through a 503A pharmacy for compounded products or a retail pharmacy for branded ones; and ongoing telehealth follow-up for titration and side-effect management. Provider type and pharmacy partner vary between programs, shaping the day-to-day experience.
What the weight-loss program costs
As captured July 2026, compounded semaglutide runs about $299 per month ongoing after a $159 first-month promotional price, and compounded tirzepatide about $399 per month ongoing after a $259 first month, flat across dose. Prepaid multi-month plans lower the effective monthly rate — the 3-month semaglutide plan is $475 (about $158/month) and the 12-month tirzepatide plan is $2,859 (about $238/month). Compounded plans carry no membership fee.
Evidence behind GLP-1 weight loss
The program’s compounds carry a documented weight-management record. STEP studied semaglutide (The New England Journal of Medicine, 2021); SURMOUNT studied tirzepatide (NEJM 2022); SURMOUNT-OSA extended tirzepatide into obstructive sleep apnea (NEJM 2024). Trial populations and endpoints vary, and individual outcomes vary — no program can promise a specific result.
Why two people lose weight differently — genetics
Response to a GLP-1 is not uniform, and part of the reason is genetic. Variants in FTO (fat-mass and obesity-associated), GLP1R (the receptor these compounds target), MC4R (central to satiety), and TCF7L2 (linked to glucose homeostasis) shape the baseline metabolism any weight-loss compound acts on. They do not predict response to a specific compound, but they describe the starting point. PlexusDx offers semaglutide and tirzepatide through its Weight Management Protocols — Semaglutide Injection, Semaglutide Oral, Tirzepatide Injection, and Tirzepatide Oral — with the Precision Peptide Genetic Test, which analyzes 14 pathways, 49 peptides, 150+ genetic insights. That is the test before you invest approach.
Not affiliated: PlexusDx has no relationship with Medvi and no commercial tie to the companies named here.
Related reading on PlexusDx: Mounjaro Weight Loss, Wegovy Weight Loss, GLP 1 Weight Loss, Tirzepatide Weight Loss.
Disclaimer: This article is educational. PlexusDx is not affiliated with Medvi and has no commercial relationship with the companies reviewed. PlexusDx offers semaglutide and tirzepatide through its own Weight Management Protocols; this review compares approaches in the GLP-1 telehealth space. The Precision Peptide Genetic Test analyzes how your genes influence peptide-related pathways — it does not predict response to any specific medication. Consult a qualified healthcare provider before beginning any peptide protocol.
Compare approaches: see the Weight Management Protocols, or take the Precision Peptide Genetic Test to understand your GLP-1 pathway first.
Frequently Asked Questions
What medications does Medvi’s weight-loss program use?
As verified July 2026, the program uses compounded semaglutide and compounded tirzepatide injections, a once-daily dissolvable GLP-1 tablet, and branded Wegovy and Zepbound through a separate membership. Semaglutide is a GLP-1 receptor agonist and tirzepatide a GIP/GLP-1 dual agonist; compounded options are not FDA-approved brand products.
Who is eligible for Medvi’s weight-loss program?
Eligibility is determined by a licensed clinician after reviewing an intake covering weight, medical history, and current medications. A prescription is issued only if criteria are met. Because clinical review governs access, not every applicant qualifies — the intake and provider assessment decide.
How much does Medvi’s weight-loss program cost?
Captured July 2026, compounded semaglutide is about $299 per month ongoing (after $159 first month) and tirzepatide about $399 (after $259), flat across dose; prepaid bundles lower the effective rate. Compounded plans have no membership fee. Verify current figures on Medvi’s site.
How does genetics affect weight-loss outcomes?
Variants in FTO, GLP1R, MC4R, and TCF7L2 shape baseline appetite, satiety, and glucose metabolism, which is part of why responses differ. The Precision Peptide Genetic Test maps these pathway-level insights; it does not predict drug response but frames the starting point for a provider conversation.
This article is part of the PlexusDx Education Hub. Browse all Peptides & GLP-1 education
Medical and Editorial Standards
Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.
Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.
Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.
Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.
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