GLP-1 Providers Under $150 a Month: Semaglutide and Tirzepatide

Last reviewed: September 4, 2026 Last updated: September 4, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

Several telehealth providers advertise compounded GLP-1 medication—semaglutide or tirzepatide—for less than $150 per month all-inclusive, but the fine print varies widely. Some require multi-month prepayment and quote an effective per-month rate; others apply the sub-$150 figure only to starting doses and raise the price as you titrate; still others bundle a clinical membership fee that pushes the true monthly outlay above $150 after an introductory period. Exactly one injectable semaglutide option and three injectable tirzepatide options hold a sub-$150 rate month-to-month with no prepayment and no dose penalty—PlexusDx microdose GLP-1 at $129, PlexusDx semaglutide injection (6-month plan) at $149, AltRx tirzepatide (1-month) at $149, and BrightMeds tirzepatide (3-month prepaid) at an effective $119 per month. The rest require either upfront commitment or accept higher recurring costs once the first shipment is complete.

At-a-glance comparison

Sources: PlexusDx pricing pages, Mochi Health checkout flow, OrderlyMeds product pages, Noom Med program page, AltRx promotional grid, BrightMeds plan page, Eden checkout flow, Fridays Health product pages, IVIM Health bundle page, Henry Meds legal program page—all captured September 4, 2026. AltRx promotional pricing states an end date of September 5, 2026.

Normalized like-for-like cost over 12 months

To compare providers fairly, we calculated the total 12-month outlay—including introductory periods, membership fees, and refill rates—then divided by twelve to show the effective monthly cost. Every derived figure below is our calculation from the published rates captured September 4, 2026.

Semaglutide injection, 12-month cost comparison

Calculation notes: AltRx 12-month: $89 × 12 = $1,068. BrightMeds 12-month: $297 × 4 = $1,188. Fridays Health 12-month: $117 × 12 = $1,404. PlexusDx 6-month plan 12-month: $149 × 12 = $1,788. OrderlyMeds 12-month: $149 starter + ($149 × 10 refills) = $1,639. Mochi Health 12-month: $99 first month + ($159 × 11 refills) = $1,848. PlexusDx month-to-month 12-month: $189 × 12 = $2,268.

Tirzepatide injection, 12-month cost comparison

Calculation notes: BrightMeds 12-month: $357 × 4 = $1,428. AltRx 12-month: $149 × 12 = $1,788. Mochi Health 12-month: $129 first month + ($189 × 11 refills) = $2,208. Fridays Health 12-month: $190 × 12 = $2,280. OrderlyMeds 12-month: $299 starter + ($299 × 10 refills) = $3,289. PlexusDx 6-month plan 12-month: $249 × 12 = $2,988. PlexusDx month-to-month 12-month: $289 × 12 = $3,468.

Microdose GLP-1, 12-month cost comparison

Calculation notes: PlexusDx 12-month: $129 × 12 = $1,548. Noom Med 12-month: $79 intro (covers 7 weeks) + 10 months remaining at $179 per 12-week cycle = $79 + (10 months ÷ 3 months per cycle × $179 per cycle) = $79 + ($179 × 3.33 cycles) = approximately $2,065; effective monthly approximately $172.08. The Noom Med calculation assumes continuous 12-week subscription renewal; confirm billing cadence at enrollment.

What drives the price spread

Four structural variables separate the sub-$150 programs from the rest:

1. Membership fees: Mochi Health, Eden, and IVIM Health unbundle clinical support into a separate monthly subscription—$99, $99, and $75 respectively after introductory periods—which pushes the all-in cost above $150 even when medication alone sits below that threshold.
2. Prepayment requirements: BrightMeds, Fridays Health, IVIM Health, and OrderlyMeds' advertised per-month figures are effective rates derived from multi-month prepayment. BrightMeds' $99/month semaglutide rate, for example, requires a $297 upfront commitment for three months; OrderlyMeds' $74.50 starter rate is a two-month prepaid package at $149 total. The prepaid structure lowers the per-month equivalent but eliminates month-to-month flexibility.
3. Dose-dependent pricing: Mochi Health and some others charge per dose tier. The $60 semaglutide rate applies to the starting dose; titration increases both medication cost and total monthly outlay. Providers with flat-rate pricing—PlexusDx, BrightMeds, AltRx—hold the advertised rate at every dose.
4. Introductory vs. refill: OrderlyMeds' semaglutide starter costs $149 for two months ($74.50 per month equivalent), but refills jump to $149 per month. The 12-month effective rate is $136.58 (our calculation). Noom Med's microdose program starts at $79 for seven weeks, then moves to $179 per 12-week cycle.

Which providers hold the sub-$150 rate month-to-month with no prepayment

Only three programs deliver compounded GLP-1 medication at or below $150 per month on a true month-to-month basis with no multi-month prepayment:

• PlexusDx microdose GLP-1 injection: $129/month, month-to-month, same price at every dose. No membership fee, no prepayment. Microdose formulation designed for maintenance or gradual titration.
• AltRx semaglutide injection (1-month plan): $89/month, month-to-month, all-inclusive. Promotional pricing states an end date of September 5, 2026; confirm current rate at checkout.
• AltRx tirzepatide injection (1-month plan): $149/month, month-to-month, all-inclusive. Promotional pricing states an end date of September 5, 2026; confirm current rate at checkout.

Every other option below $150 either requires prepayment (BrightMeds, OrderlyMeds, Fridays Health, IVIM Health), charges a separate ongoing membership (Mochi Health, Eden), or applies the rate only to starting doses or introductory periods.

Decision factors beyond the monthly figure

Service quality and patient experience

Price is one input; reliability, responsiveness, and continuity of care are others. Review evidence captured September 4, 2026 shows variation:

• PlexusDx holds a 4.2-star rating on Trustpilot, with 76 percent of reviews at five stars and 81 percent at four stars or higher.
• Mochi Health holds a 4.5-star rating with approximately 18,000 Trustpilot reviews. One captured 1-star report describes a provider appearing late and not engaging during the visit.
• OrderlyMeds holds a 3.6-star rating with approximately 634 Trustpilot reviews. Captured 1-star and 2-star reviews cite fast charging but slow refunds, non-response to inquiries, delayed shipping, unannounced pharmacy changes, and continued marketing calls and texts after opt-out requests.
• Eden holds a 4.5-star rating with approximately 5,000 Trustpilot reviews. One captured 1-star report describes an 11-day order delay and repeated requests for medical records that Eden had previously issued to the patient.
• Henry Meds holds a 4.4-star rating with approximately 13,000 Trustpilot reviews.
• Fridays Health holds a 4.2-star rating with approximately 4,700 Trustpilot reviews.
• Noom Med holds a 4.5-star profile-wide rating with approximately 67,000 reviews; this figure encompasses Noom's broader weight-loss programs and is not GLP-1-specific. One captured Reddit complaint centers on slow titration and perceived lack of efficacy in the microdose program.

These ratings and anecdotes are individual reports, not established facts. Confirm current service quality by reviewing recent feedback on Trustpilot, Reddit, and other independent platforms before enrollment.

Dose flexibility and titration policy

Providers with flat-rate pricing—PlexusDx, BrightMeds, AltRx (during the promotional period)—hold the advertised rate through titration. Dose-tiered programs such as Mochi Health increase the monthly cost as your clinician raises your dose. If you anticipate titrating to maintenance doses above the starting tier, calculate the likely 6- or 12-month outlay at the higher dose before committing.

Medication route and formulation

Most sub-$150 options are compounded injectable semaglutide or tirzepatide. Henry Meds offers oral semaglutide tablets at $179/month (3-month prepaid plan) and compounded liraglutide injection at $179/month. PlexusDx offers oral semaglutide capsules at $289/month month-to-month ($269/month 3-month plan, $249/month 6-month plan) and oral tirzepatide capsules at $349/month month-to-month ($299/month 3-month plan, $279/month 6-month plan)—both above the $150 threshold but available for patients who prefer or require oral administration. Eden's route varies by clinician determination; confirm injectable or oral availability at intake.

Regulatory and compounding status

Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies. Verify the compounding-pharmacy accreditation and state licensure of any provider before enrollment.

Choose AltRx if…

You want the lowest advertised semaglutide rate with month-to-month flexibility and can verify the promotional pricing before the stated September 5, 2026 end date. AltRx semaglutide at $89/month and tirzepatide at $149/month (1-month plans) are the floor prices in this comparison. Confirm at checkout that the promotional rate remains active and that no hidden fees or membership subscriptions apply. Review availability is limited; we found no Trustpilot profile or significant independent feedback captured as of September 4, 2026.

Choose BrightMeds if…

You can commit to a 3-month prepayment and want flat-rate pricing that includes every dose. BrightMeds semaglutide costs $297 total for three months ($99/month effective, our calculation) and tirzepatide costs $357 total for three months ($119/month effective, our calculation). Both rates hold through titration. Verify state availability and confirm the prepayment cadence renews automatically or requires manual re-enrollment every quarter.

Choose Mochi Health if…

You qualify for the starting dose, value high Trustpilot volume and rating (4.5 stars, approximately 18,000 reviews), and accept that the all-in monthly cost—medication plus membership—rises to $159 for semaglutide or $189 for tirzepatide after the first month. The membership fee of $99/month (after a $39 introductory month) continues regardless of dose. Budget for higher medication charges as you titrate; confirm the per-dose schedule before enrollment.

Choose OrderlyMeds if…

You want an initial two-month trial at a reduced effective rate and can accept the step-up to standard monthly pricing afterward. OrderlyMeds semaglutide starts at $149 total for two months ($74.50/month effective, our calculation), then $149/month; tirzepatide starts at $299 total for two months ($149.50/month effective, our calculation), then $299/month. The 12-month effective semaglutide rate is $136.58 (our calculation), keeping it below $150 overall. Be aware of the 3.6-star Trustpilot rating and captured complaints regarding billing disputes, delayed shipping, and post-cancellation contact.

Choose Henry Meds if…

You prefer liraglutide injection at $179/month or oral semaglutide tablets at $179/month (3-month prepaid plan, $537 total). Both options exceed the $150 threshold but offer alternative GLP-1 mechanisms or routes. Henry Meds holds a 4.4-star Trustpilot rating with approximately 13,000 reviews. No separate membership fee applies; medication, provider access, and shipping are bundled. Henry Meds does not offer injectable tirzepatide; tirzepatide is available only as an oral dissolving tablet and is not directly comparable to injectable tirzepatide programs.

Choose Noom Med if…

You want a microdose GLP-1 program paired with Noom's behavioral coaching platform and can accept a 12-week subscription billing cycle at $179 per cycle (after a $79 introductory period covering seven weeks). The effective monthly rate over 12 months is approximately $172 (our calculation), above the $150 threshold. Noom Med's 4.5-star profile-wide rating reflects its broader weight-loss ecosystem; GLP-1-specific feedback is less granular. One captured Reddit report describes slow titration and limited weight-loss results; individual outcomes vary.

Where PlexusDx fits

PlexusDx offers the lowest true month-to-month microdose GLP-1 injection rate at $129 per month, with no membership fee, no prepayment, and the same price at every dose. For patients seeking maintenance therapy, transitioning off higher-dose protocols, or titrating gradually without upfront financial commitment, the microdose option delivers predictable monthly cost and maximum flexibility. The 4.2-star Trustpilot rating—with 81 percent of reviews at four stars or higher—reflects consistent service quality as of September 4, 2026.

For standard-dose injectable semaglutide, PlexusDx charges $189/month month-to-month, $169/month on a 3-month plan, and $149/month on a 6-month plan. The 6-month rate ties AltRx tirzepatide for the second-lowest sub-$150 option and undercuts every semaglutide competitor except AltRx's promotional rate and BrightMeds' 3-month prepaid plan. The same flat-rate model applies: no dose penalty, no membership, no hidden fees.

PlexusDx tirzepatide injection is priced at $289/month month-to-month, $269/month on a 3-month plan, and $249/month on a 6-month plan—above the $150 threshold but competitive with Mochi Health's ongoing rate and OrderlyMeds' refill rate. For patients who prioritize transparent pricing, same-price-at-every-dose simplicity, and strong review performance, PlexusDx balances cost predictability with service reliability.

What these comparisons do not address

This analysis uses advertised and checkout-verified pricing captured September 4, 2026. It does not account for state-specific restrictions, individual eligibility, prior-authorization requirements, or clinician-determined dose adjustments. It does not guarantee uninterrupted supply during compounding-pharmacy shortages or FDA enforcement actions. It does not project long-term cost if a provider exits the market, changes its pricing model, or loses pharmacy partnerships. Confirm current pricing, state availability, and refill policy at checkout before enrollment.

Methodology and freshness

We captured advertised pricing, membership fees, prepayment terms, and review ratings from each provider's public website, checkout flow, or legal program page on September 4, 2026. Where promotional or introductory rates appeared, we verified the stated expiration date and labeled the figure accordingly. Every 12-month total and effective monthly figure in this article is our calculation, derived by adding introductory charges, ongoing refill rates, and membership fees over twelve months, then dividing by twelve. We did not submit payment or complete enrollment for providers beyond PlexusDx. AltRx promotional pricing states an end date of September 5, 2026; confirm current rates before relying on those figures. Trustpilot ratings and review counts were captured September 4, 2026 and reflect each provider's profile at that date. Individual review anecdotes are paraphrased from captured reports and presented as allegations, not verified facts. Compounded-medication regulatory status and PlexusDx 503A pharmacy partnerships are stated as published by each provider.

Frequently Asked Questions

Which GLP-1 provider truly costs under $150 per month with no prepayment?

PlexusDx microdose GLP-1 at $129/month, AltRx semaglutide at $89/month, and AltRx tirzepatide at $149/month are the only verified month-to-month options under $150 with no multi-month prepayment requirement. AltRx promotional pricing states an expiration of September 5, 2026; confirm current rates at checkout. Every other sub-$150 program requires prepayment or adds membership fees that push the all-in monthly cost above $150.

Do Mochi Health and Eden really cost under $150 per month?

Mochi Health's first-month all-in cost is $99 for semaglutide and $129 for tirzepatide, but ongoing months cost $159 and $189 respectively once the $99 membership fee applies. Eden's first-month all-in semaglutide cost is $138, but ongoing months cost $198 after the membership fee rises to $99. Both exceed $150 per month after the introductory period, and both charge more at higher doses.

What is the true 12-month cost of OrderlyMeds compared to PlexusDx?

OrderlyMeds semaglutide costs $149 for the first two months, then $149 per month, yielding a 12-month total of $1,639 and an effective monthly rate of $136.58 (our calculation). PlexusDx semaglutide (6-month plan) costs $149 per month every month, yielding a 12-month total of $1,788. OrderlyMeds is $149 cheaper over twelve months, but PlexusDx holds the same rate at every dose and carries a higher Trustpilot rating (4.2 stars vs. 3.6 stars, captured September 4, 2026).

Are compounded GLP-1 medications under $150 safe and effective?

Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies. Verify the accreditation, state licensure, and inspection record of any compounding pharmacy before starting treatment.

Does PlexusDx raise the price when I titrate to a higher dose?

No. PlexusDx charges the same monthly rate at every dose for every medication. Microdose GLP-1 is $129/month, semaglutide injection is $189/month month-to-month ($169/month 3-month, $149/month 6-month), and tirzepatide injection is $289/month month-to-month ($269/month 3-month, $249/month 6-month). Your clinician adjusts your dose based on tolerance and response; the price does not change.

Sources

• PlexusDx pricing pages and product pages, accessed September 4, 2026
• Mochi Health checkout flow and membership terms, accessed September 4, 2026
• OrderlyMeds product pages and plan details, accessed September 4, 2026
• Noom Med program page and subscription terms, accessed September 4, 2026
• AltRx promotional pricing grid, accessed September 4, 2026
• BrightMeds plan page and prepayment structure, accessed September 4, 2026
• Eden checkout flow and membership terms, accessed September 4, 2026
• Fridays Health product pages, accessed September 4, 2026
• IVIM Health bundle page and membership terms, accessed September 4, 2026
• Henry Meds legal program page and medication pricing, accessed September 4, 2026
• Trustpilot profiles for PlexusDx, Mochi Health, OrderlyMeds, Eden, Henry Meds, Fridays Health, and Noom, accessed September 4, 2026
• Reddit r/Semaglutide and r/GLP1 community discussions, accessed September 4, 2026

Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.