Last reviewed: May 12, 2026 Last updated: May 12, 2026

Written by: Jay Hastings , CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx delivers personalized health reports

which detail how genetic traits affect individual well-being. The current exploration focuses on Apolipoprotein B (ApoB), which is the main protein connected to both bad cholesterol levels and heart disease risk. We will examine how ApoB functions and its effects on your health. The protein ApoB plays a vital function by helping create three main lipoproteins which include LDL, VLDL and IDL. The combination of these lipoproteins makes up what people usually call 'bad cholesterol.' The concentration of ApoB in your bloodstream functions as an indicator of the quantity of 'bad cholesterol' present. Scientific studies demonstrate that reduced ApoB levels correspond with lower heart disease risk. Although ApoB has protective functions against harmful bacteria the body may face lower ApoB levels might increase infection risk. ApoB levels above normal range have been associated with greater risks for heart disease, diabetes, and cancer. Genetically elevated ApoB levels might contribute to the development of heart disease and Alzheimer's disease. The genetic implications of ApoB are essential to understand because genetic factors explain 70% of the differences in individual ApoB levels. The genes that regulate ApoB production have a major impact on your susceptibility to different diseases. Your ApoB levels are influenced by your lifestyle decisions as well as your medical condition and medication use. High-sugar diets along with saturated fats, tobacco use, and specific medications can lead to higher ApoB levels. Multiple health conditions such as obesity and thyroid disorders along with liver and kidney diseases can affect ApoB levels. ApoB levels fluctuate during pregnancy and menopause. Conditions such as an overactive thyroid or liver disease and the use of particular medications can lead to decreased ApoB levels. The level of Apolipoprotein B (ApoB) determines the extent of your risk for heart disease along with other health disorders. Knowing your genetic tendency towards ApoB levels enables you to make knowledgeable health choices. Access the Precision Health & Wellness tests provided by PlexusDx to understand your genetic traits and uncover potential health risks. Start your journey to a healthier future by visiting PlexusDx.com or checking their products on Amazon and Walmart.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

Real prescribers. Published prices. No surprises.

Licensed providers in all 50 states. Online intake. No insurance, no membership required.

Start My Intake →

~60 seconds · $0 charged until your provider approves