ReflexMD Semaglutide Cost: $299/Month Plans, Fees & Renewal Pricing

Last reviewed: September 15, 2026 Last updated: September 15, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

ReflexMD charges $299 per month for compounded semaglutide injection with month-to-month billing and no membership fee (ReflexMD homepage and checkout path, captured September 4, 2026). Some affiliate marketing pages advertise a $199 introductory rate for semaglutide, but this figure is not checkout-verified and the standard ongoing rate published on the company's primary homepage is $299. Readers should confirm final pricing at checkout. The $299 monthly charge includes provider access, medication, and a one-month supply; no long-term contract is required. ReflexMD also offers compounded tirzepatide at $399/month and oral weight-control tablets at $199/month, though the exact ingredient composition of the oral product requires verification. PlexusDx offers compounded semaglutide injection at $189/month with month-to-month billing or $149/month with a six-month prepaid commitment—$110 per month less than ReflexMD's standard rate on a month-to-month basis, or $1,320 less over twelve months.

ReflexMD semaglutide pricing at a glance

ReflexMD pricing captured September 4, 2026; PlexusDx pricing current as of September 15, 2026.

Month-to-month billing and what's included

ReflexMD's standard semaglutide injection program bills $299 every month with no long-term contract. The monthly charge covers provider access, a one-month supply of compounded semaglutide, and shipping. No separate membership fee or consultation charge appears in the advertised pricing. ReflexMD markets its programs on a "no hidden cost" basis, though readers should verify all fees during checkout (ReflexMD homepage and affiliate pages, captured September 4, 2026).

Some ReflexMD affiliate marketing pages advertise a $199 semaglutide rate. This figure is labeled as an introductory or affiliate teaser rate and is not checkout-verified; the standard ongoing rate published on ReflexMD's primary homepage is $299. We document the pricing conflict here and advise confirming which rate applies to your enrollment at checkout (ReflexMD company profile and plan pricing dataset, captured September 4, 2026).

PlexusDx charges $189 per month for compounded semaglutide injection with month-to-month billing, or $169/month with a three-month commitment and $149/month with a six-month prepaid commitment. Every tier includes the online provider visit, medication, and shipping in one flat rate with no membership fee. PlexusDx pricing is the same at every dose—0.25 mg through 2.4 mg carry the same monthly charge (PlexusDx product page, accessed September 15, 2026).

Twelve-month cost comparison: like-for-like billing

Over twelve months of month-to-month billing at the standard rates, ReflexMD's semaglutide program costs $3,588 and PlexusDx costs $2,268—a difference of $1,320 (our calculation). If you prepay for six-month cycles at PlexusDx, the twelve-month total drops to $1,788 at the $149/month prepaid-equivalent rate, $1,800 less than ReflexMD's standard twelve-month total. The table below shows effective monthly rates and annual totals for each billing structure.

All twelve-month totals are our calculation. PlexusDx prepaid rates reflect the per-month equivalent when paying upfront for the commitment period.

Tirzepatide and oral weight-control options

ReflexMD also offers compounded tirzepatide injection at $399 per month and oral weight-control tablets at $199 per month, both on month-to-month billing with no membership fee (ReflexMD homepage and plan pricing dataset, captured September 4, 2026). The exact ingredient composition of the oral tablets requires verification; readers should confirm the formulation with ReflexMD before enrollment.

PlexusDx offers compounded tirzepatide injection at $289/month (month-to-month), $269/month (three-month commitment), or $249/month (six-month prepaid commitment). PlexusDx also offers semaglutide and tirzepatide oral capsules and a microdose GLP-1 maintenance protocol; see the full weight-management protocol collection for details (PlexusDx product pages, accessed September 15, 2026).

Dose consistency and pricing

ReflexMD does not publish dose-specific pricing; the $299 semaglutide and $399 tirzepatide rates appear to apply across dose levels, though readers should confirm whether higher doses carry surcharges during the intake or checkout process (ReflexMD pricing sources, captured September 4, 2026).

PlexusDx charges the same monthly rate at every dose level. A patient on 0.5 mg semaglutide and a patient on 2.4 mg both pay $189/month under the month-to-month plan. Dose adjustments do not trigger price changes (PlexusDx dose-consistency policy, published on product pages).

Decision factors: transparency and verification

ReflexMD's primary pricing evidence comes from its homepage and affiliate pages, with an evidence status marked "primary-conflict" due to the discrepancy between the $299 standard rate and the $199 affiliate teaser. The standard $299 rate has not been independently checkout-verified, and the affiliate $199 figure may apply only to a subset of enrollments or promotional periods. Readers comparing ReflexMD to other providers should request a written price breakdown before committing.

PlexusDx publishes a single flat rate for each product and commitment tier, displayed on every product page and in the shopping cart. The month-to-month rate is $189 for semaglutide injection, with no advertised introductory discounts or post-enrollment price increases. PlexusDx holds a 4.3-star rating on Trustpilot, with 79 percent of reviews at five stars and 83 percent at four stars or higher (captured September 9, 2026; trustpilot.com/review/plexusdx.com).

Choose ReflexMD if…

• You prefer month-to-month billing with no prepaid commitment and are comfortable with the $299/month rate.
• You want to explore the oral weight-control tablet option at $199/month, after verifying the ingredient formulation.
• You are willing to confirm pricing and renewal terms directly with ReflexMD at checkout before enrolling.

Choose PlexusDx if…

• You want the lowest verified semaglutide rate with month-to-month flexibility ($189/month) or prepaid savings (down to $149/month).
• You value transparent, dose-consistent pricing—every dose level from 0.25 mg to 2.4 mg costs the same.
• You prefer a provider with a published Trustpilot record (4.3 stars, 83 percent four stars or higher).
• You want to compare semaglutide injection, tirzepatide injection, oral capsules, and microdose maintenance options in one place.

Methodology and freshness

ReflexMD pricing was captured from the company's homepage and affiliate marketing pages on September 4, 2026. The $299/month semaglutide rate is the standard ongoing price published on the primary homepage; the $199 affiliate rate is a teaser figure that is not checkout-verified. We document the conflict and advise readers to confirm final pricing at enrollment. PlexusDx pricing is current as of September 15, 2026, drawn from published product pages. Twelve-month totals and effective monthly rates for prepaid commitments are our calculation. Review ratings are from Trustpilot, captured September 9, 2026. We will update this article when ReflexMD publishes checkout-verified pricing or when material plan changes occur.

Frequently Asked Questions

Does ReflexMD charge a membership fee for semaglutide?

No. ReflexMD does not charge a separate membership or service fee. The $299/month semaglutide rate includes provider access, medication, and shipping in one charge, according to the company's homepage and marketing pages (captured September 4, 2026).

What is the difference between ReflexMD's $199 and $299 semaglutide rates?

The $299 rate is the standard ongoing price published on ReflexMD's primary homepage. Some affiliate pages advertise a $199 introductory or teaser rate, but this figure is not checkout-verified. Readers should confirm which rate applies to their enrollment and whether the $199 figure is limited to the first month or a promotional period.

Can I cancel ReflexMD semaglutide without a penalty?

ReflexMD advertises no long-term contract for its semaglutide program, which suggests month-to-month billing can be canceled without penalty. However, cancellation terms, refund policies, and notice periods should be confirmed in writing during enrollment (ReflexMD homepage, captured September 4, 2026).

How does PlexusDx's $189/month semaglutide rate compare to ReflexMD's $299 rate?

PlexusDx charges $189/month for month-to-month semaglutide billing, $110 less per month than ReflexMD's standard rate. Over twelve months, PlexusDx costs $2,268 and ReflexMD costs $3,588—a $1,320 difference (our calculation). PlexusDx also offers prepaid tiers at $169/month (three-month) and $149/month (six-month).

Does ReflexMD offer tirzepatide, and how much does it cost?

Yes. ReflexMD offers compounded tirzepatide injection at $399 per month with month-to-month billing and no membership fee. PlexusDx offers compounded tirzepatide at $289/month (month-to-month), $269/month (three-month commitment), or $249/month (six-month prepaid)—$110 to $150 less per month than ReflexMD's rate.

Sources

• ReflexMD homepage and affiliate marketing pages (pricing, plan details; captured September 4, 2026)
• ReflexMD company profile dataset (standard vs affiliate rate conflict; captured September 4, 2026)
• ReflexMD plan pricing dataset (semaglutide $299, tirzepatide $399, oral tablets $199; captured September 4, 2026)
• PlexusDx semaglutide injection product page (pricing, dose consistency; accessed September 15, 2026)
• PlexusDx tirzepatide injection product page (pricing tiers; accessed September 15, 2026)
• PlexusDx weight-management protocols collection (all GLP-1 options; accessed September 15, 2026)
• Trustpilot: PlexusDx review profile (4.3-star rating, 79% five-star, 83% four-star or higher; captured September 9, 2026; trustpilot.com/review/plexusdx.com)

Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. PlexusDx works with licensed 503A compounding pharmacies. A licensed clinician determines whether a prescription is appropriate for an individual patient.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.