Last reviewed: September 17, 2026 Last updated: September 17, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

Pomegranate Health's website advertises $119/month for compounded semaglutide injection and $149/month for tirzepatide with B6, captured September 4, 2026 from its product pages and checkout flow. Both pages state "dose tiers in app" but do not publish pricing for each tier. The evidence does not confirm whether the $119 and $149 figures represent flat rates across all dose levels or entry-level pricing that increases as dose escalates. Readers who need to know the cost at maintenance doses—where most people spend the majority of their treatment time—should verify the full dose ladder inside the Pomegranate app or by contacting support before committing. PlexusDx charges the same monthly rate at every dose: $189/month for semaglutide injection (month-to-month), with no surprise increases when your provider adjusts your prescription.

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At-a-glance: Pomegranate Health vs PlexusDx

Factor Pomegranate Health PlexusDx
Semaglutide injection (advertised rate) $119/month
Dose tiers in app; per-tier pricing not published
$189/month (MTM)
$169/month (3-month prepaid: our calculation)
$149/month (6-month prepaid: our calculation)
Same price at every dose
Tirzepatide injection (advertised rate) $149/month (tirzepatide + B6)
Dose tiers in app; per-tier pricing not published
$289/month (MTM)
$269/month (3-month prepaid: our calculation)
$249/month (6-month prepaid: our calculation)
Same price at every dose
Membership / service fee $0 (product page states no membership fee; historical materials mention consult deposit—verify at checkout) $0
Billing cadence Monthly Monthly, 3-month prepay, or 6-month prepay
Dose-escalation policy transparency Dose tiers referenced; full pricing not published on website Same price at every dose; published before signup
Evidence capture September 4, 2026
joinpomegranate.com/products/compounded-semaglutide
app.joinpomegranate.com/pricing
September 4, 2026
plexusdx.com

What the evidence shows—and where it stops

On September 4, 2026, Pomegranate Health's product page for compounded semaglutide injection displayed $119/month, and its tirzepatide pricing page showed $149/month for tirzepatide with B6. Both pages include the phrase "dose tiers in app" but do not publish the price at each tier. The checkout flow confirmed the $119 and $149 figures but did not display a dose-by-dose pricing ladder.

This leaves three scenarios possible:

  1. Flat pricing: $119 and $149 remain constant regardless of dose—similar to PlexusDx's model.
  2. Entry-level pricing: The advertised figures apply only to starting doses (e.g., 0.25 mg semaglutide, 2.5 mg tirzepatide), and the price increases when a provider escalates to maintenance levels (1 mg or 2.4 mg semaglutide, 10 mg or 15 mg tirzepatide).
  3. Hybrid model: Some tiers share a price; others carry surcharges.

The evidence does not confirm which scenario applies. Readers planning six to twelve months of treatment—where most time is spent at maintenance doses, not starter doses—need the full ladder before they can project total cost or compare effectively.

12-month cost: what we can calculate vs what remains uncertain

If Pomegranate Health's advertised rates apply at every dose—an assumption the evidence does not verify—the 12-month costs would be:

  • Semaglutide injection: $119/month × 12 = $1,428/year (our calculation, assuming flat pricing)
  • Tirzepatide + B6 injection: $149/month × 12 = $1,788/year (our calculation, assuming flat pricing)

PlexusDx's documented same-price-at-every-dose model yields:

  • Semaglutide injection (month-to-month): $189/month × 12 = $2,268/year
  • Semaglutide injection (6-month prepaid): $149/month × 12 = $1,788/year (our calculation)
  • Tirzepatide injection (month-to-month): $289/month × 12 = $3,468/year
  • Tirzepatide injection (6-month prepaid): $249/month × 12 = $2,988/year (our calculation)
Medication Pomegranate Health
(assuming flat pricing—unverified)
PlexusDx MTM PlexusDx 6-month
Semaglutide injection $1,428/year $2,268/year $1,788/year (our calculation)
Tirzepatide injection $1,788/year $3,468/year $2,988/year (our calculation)

Critical limitation: The Pomegranate figures rest on the assumption that $119 and $149 apply at all doses. If the provider increases price at higher tiers, the annual cost rises, and the gap narrows or reverses. Without published per-tier pricing, readers cannot know their maintenance-phase cost before enrollment.

Know your cost at 0.25 mg—and at 2.4 mg—before you commit

PlexusDx charges $189/month for semaglutide injection at every dose. A licensed provider reviews your intake and determines whether a prescription is appropriate.

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Why same-price-at-every-dose models matter

GLP-1 treatment typically begins at a low dose—0.25 mg for semaglutide, 2.5 mg for tirzepatide—and escalates every four weeks until the patient reaches an effective maintenance dose or the maximum approved level. Most people spend one to two months at starter doses and six to ten months (or longer) at maintenance doses.

If a provider's advertised price applies only to the starter phase, a patient may budget for $119/month and then face $179, $229, or another undisclosed figure when the prescription moves to 1 mg or 2.4 mg semaglutide. The total annual cost becomes unpredictable, and comparison shopping before enrollment becomes impossible.

PlexusDx's same-price-at-every-dose policy eliminates that uncertainty: $189/month for semaglutide injection whether you are at 0.25 mg or 2.4 mg, $289/month for tirzepatide injection whether you are at 2.5 mg or 15 mg. The month-to-month option requires no prepayment; the 3-month and 6-month plans offer per-month discounts ($169 and $149 for semaglutide, $269 and $249 for tirzepatide—our calculation of the prepaid equivalent) in exchange for upfront commitment.

Other decision factors

Membership and visit fees

Pomegranate Health's current product pages state "no membership/extra fee" (captured September 4, 2026). Historical materials referenced a consult deposit, but the checkout flow on September 4 showed $0 membership fee. Readers should confirm at checkout whether any visit or consultation charge applies separately from the medication cost.

PlexusDx charges $0 membership fee. The monthly medication price covers the provider visit, prescription, compounded medication, and shipping.

Medication formulation

Pomegranate Health's tirzepatide product is described as "tirzepatide + B6" (vitamin B6). The semaglutide product page does not mention additives. Both are compounded medications supplied by a partner pharmacy.

PlexusDx offers compounded semaglutide injection and compounded tirzepatide injection without added vitamins or amino acids, as well as oral semaglutide capsules, oral tirzepatide capsules, and a microdose GLP-1 injection protocol for maintenance or modest weight goals.

Billing flexibility

Pomegranate Health bills monthly with a one-month supply. PlexusDx offers month-to-month billing (cancel anytime, no prepayment) and optional 3-month or 6-month prepaid plans that lower the per-month rate.

Choose Pomegranate Health if…

  • You confirm inside the app that the $119 or $149 rate applies at the dose your provider prescribes, and that rate remains lower than alternatives over your intended treatment horizon.
  • You prefer a tirzepatide formulation that includes B6.
  • You are comfortable enrolling without seeing the full dose-pricing ladder published on the website.

Choose PlexusDx if…

  • You want to know your monthly cost at every possible dose—starter, mid-range, and maintenance—before you complete intake.
  • You value the flexibility to switch between month-to-month and prepaid plans, or to cancel without forfeiting a multi-month payment.
  • You prefer a provider that publishes one price for each medication and applies it uniformly regardless of dose escalation.
  • You want access to oral GLP-1 capsules or a microdose maintenance protocol in addition to standard injection options.

Methodology and freshness

We captured Pomegranate Health's advertised pricing, product descriptions, and checkout flow on September 4, 2026 from joinpomegranate.com/products/compounded-semaglutide and app.joinpomegranate.com/pricing. Both pages state "dose tiers in app" but do not publish per-tier pricing. The $119 semaglutide and $149 tirzepatide figures are labeled as monthly rates in both the advertised and checkout contexts; we found no indication they are introductory, first-month, or promotional rates. However, we cannot verify whether these rates apply at all dose levels or only at entry-level doses.

PlexusDx pricing is current as of September 4, 2026 and is published at plexusdx.com. The 12-month cost calculations multiply the stated monthly rate by 12 and are labeled "our calculation" where applicable. Prepaid per-month equivalents (3-month and 6-month plans) are derived by dividing the total prepaid amount by the number of months and are also labeled "our calculation."

We recommend that readers verify Pomegranate Health's full dose ladder and any visit or consultation fees inside the app or by contacting support before enrollment, especially if planning treatment longer than three months.

Frequently Asked Questions

Does Pomegranate Health charge more when my dose increases?

Pomegranate Health's website states "dose tiers in app" but does not publish pricing for each tier. The advertised $119/month semaglutide and $149/month tirzepatide rates may apply at all doses, or they may represent entry-level pricing that increases at higher tiers. Confirm the full pricing ladder inside the app or with support before committing.

What is PlexusDx's dose-escalation pricing policy?

PlexusDx charges the same monthly rate at every dose. Semaglutide injection is $189/month whether you are prescribed 0.25 mg or 2.4 mg. Tirzepatide injection is $289/month whether you are prescribed 2.5 mg or 15 mg. There are no surprise increases when your provider adjusts your prescription.

Is the $119 Pomegranate semaglutide price a first-month promotion?

No indication of introductory or promotional pricing was found in the evidence captured September 4, 2026. The $119 figure appears in both advertised and checkout contexts as a standard monthly rate. However, per-tier pricing is not published, so confirm whether your prescribed dose falls under that rate.

How does PlexusDx's 6-month prepaid semaglutide price compare to Pomegranate's monthly rate?

PlexusDx's 6-month prepaid semaglutide plan works out to $149/month (our calculation: 6 × $149 = $894 upfront), which is $30/month higher than Pomegranate's advertised $119/month—if that $119 rate applies at your maintenance dose. PlexusDx's month-to-month rate is $189/month with no prepayment required.

Does Pomegranate Health charge a membership or consultation fee?

The product pages captured September 4, 2026 state "no membership/extra fee," and the checkout flow showed $0 membership fee. Historical materials mention a consult deposit, so verify at checkout whether any separate visit or consultation charge applies beyond the monthly medication cost.

Sources

  • Pomegranate Health compounded semaglutide product page: joinpomegranate.com/products/compounded-semaglutide (accessed September 4, 2026)
  • Pomegranate Health pricing page: app.joinpomegranate.com/pricing (accessed September 4, 2026)
  • PlexusDx semaglutide injection: plexusdx.com/products/semaglutide-injection (accessed September 4, 2026)
  • PlexusDx tirzepatide injection: plexusdx.com/products/tirzepatide-injection (accessed September 4, 2026)
  • PlexusDx Trustpilot profile: trustpilot.com/review/plexusdx.com (accessed September 9, 2026)

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Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

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