Last reviewed: September 17, 2026
Last updated: September 17, 2026
Written by: Jay Hastings, CEO of PlexusDx
Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.
Medically reviewed by: Jayden Lee, PharmD, EMBA
Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.
PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.
The short answer
TrimRx advertises semaglutide at $199 per month, but its verified checkout charges $299 month-to-month (captured July 18, 2026). Neither the $199 figure nor a $349 advertised tirzepatide rate appeared in the signup flow we completed. That pricing gap matters because five alternatives deliver compounded GLP-1 medication at verified checkout rates lower than TrimRx's actual month-to-month charges. PlexusDx charges $189 per month for semaglutide injection and $289 for tirzepatide, both billed monthly with no prepayment. Eden, Peak Wellness, and Embody also undercut TrimRx's checkout pricing in specific plan structures. TrimRx does offer a 12-month prepaid option—$2,218 for semaglutide, which works out to $184.83 per month—but that plan requires full upfront payment and carries no refund for unused months. If you want lower recurring costs, monthly billing flexibility, or transparent checkout pricing, this comparison shows which alternatives deliver them and at what total cost over 12 months.
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At-a-glance: TrimRx vs verified alternatives
| Provider |
Semaglutide MTM |
Tirzepatide MTM |
Billing |
Best 12-mo Cost (Sema) |
| TrimRx |
$299/mo (checkout) |
$399/mo (checkout) |
Prepaid lump sum for multi-mo |
$2,218 (12-mo prepaid) |
| PlexusDx |
$189/mo month-to-month |
$289/mo month-to-month |
Monthly (no prepay) |
$1,788 (6-mo plan) |
| Eden |
$198/mo (all-in) |
$298/mo (all-in) |
Monthly |
$2,376 |
| Peak Wellness |
$249/mo |
$349/mo |
Monthly |
$2,988 |
| Embody |
$299/mo |
$349/mo |
Monthly |
$3,588 |
| Found |
$289/mo (cash) |
$359/mo (cash) |
Monthly or 12-mo prepaid |
From $2,028 (12-mo prepaid) |
Captured July 17–23, 2026 (Eden, Peak, Embody, Found) and July 18, 2026 (TrimRx, PlexusDx). Eden's all-in rate includes a required $99/month membership. TrimRx advertised figures ($199 semaglutide, $299–$349 tirzepatide) did not appear at checkout; verified month-to-month rates shown.
The advertised-vs-checkout pricing gap at TrimRx
TrimRx's website advertises semaglutide at $199 per month and tirzepatide at figures between $299 and $349 per month, depending on the page. When we completed a full signup flow on July 18, 2026, the checkout screen charged $299 per month for semaglutide and $399 per month for tirzepatide on the month-to-month plan. Neither the $199 semaglutide figure nor the $349 tirzepatide figure appeared at any point in the process. This discrepancy matters because many comparisons and search results still cite the advertised figures. If you land on TrimRx's homepage expecting $199 semaglutide, confirm the actual rate at checkout before committing to any plan length.
Normalized 12-month cost: what you actually pay
Multi-month plans reduce per-month rates, but billing structure determines whether you pay upfront or spread the cost. Below we calculate the true 12-month outlay for TrimRx and each verified alternative, separating prepaid from monthly-billed options. All per-month rates derived from prepaid totals are labeled our calculation.
TrimRx semaglutide over 12 months
-
Month-to-month ($299/mo): $299 × 12 = $3,588 over 12 months
-
3-month plan ($748 prepaid): $249.33/month (our calculation); four cycles = $2,992 over 12 months
-
6-month plan ($1,268 prepaid): $211.33/month (our calculation); two cycles = $2,536 over 12 months
-
12-month plan ($2,218 prepaid): $184.83/month (our calculation); $2,218 over 12 months
TrimRx's 12-month prepaid plan delivers the lowest per-month rate among all providers in this comparison for semaglutide injection—$184.83 per month. That plan, however, requires $2,218 upfront and carries no refund for unused medication or remaining months if you stop early.
TrimRx tirzepatide over 12 months
-
Month-to-month ($399/mo): $399 × 12 = $4,788 over 12 months
-
3-month plan ($1,068 prepaid): $356/month (our calculation); four cycles = $4,272 over 12 months
-
6-month plan ($1,918 prepaid): $319.67/month (our calculation); two cycles = $3,836 over 12 months
-
12-month plan ($3,518 prepaid): $293.17/month (our calculation); $3,518 over 12 months
PlexusDx semaglutide injection over 12 months
-
Month-to-month ($189/mo): $189 × 12 = $2,268 over 12 months
-
3-month plan ($169/mo, billed monthly): $169 × 12 = $2,028 over 12 months
-
6-month plan ($149/mo, billed monthly): $149 × 12 = $1,788 over 12 months
PlexusDx bills multi-month plans as recurring monthly charges, not a single upfront total. The 6-month rate of $149 per month continues each month you remain enrolled, yielding a 12-month total of $1,788—$430 less than TrimRx's 12-month prepaid option and $480 less than TrimRx's month-to-month rate over the same period.
PlexusDx tirzepatide injection over 12 months
-
Month-to-month ($289/mo): $289 × 12 = $3,468 over 12 months
-
3-month plan ($269/mo, billed monthly): $269 × 12 = $3,228 over 12 months
-
6-month plan ($249/mo, billed monthly): $249 × 12 = $2,988 over 12 months
PlexusDx's tirzepatide 6-month plan costs $2,988 over 12 months, $530 less than TrimRx's 12-month prepaid tirzepatide total and $1,800 less than TrimRx's month-to-month rate.
Other verified alternatives over 12 months
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Eden semaglutide: $198/month all-in (includes required $99/month membership) = $2,376 over 12 months
-
Eden tirzepatide: $298/month all-in = $3,576 over 12 months
-
Peak Wellness semaglutide: $249/month = $2,988 over 12 months
-
Peak Wellness tirzepatide: $349/month = $4,188 over 12 months
-
Embody semaglutide: $299/month = $3,588 over 12 months
-
Embody tirzepatide: $349/month = $4,188 over 12 months
-
Found semaglutide (month-to-month cash): $289/month = $3,468 over 12 months
-
Found semaglutide (12-month prepaid): from $2,028 over 12 months (captured July 17–23, 2026; confirm current rate at checkout)
-
Found tirzepatide (month-to-month cash): $359/month = $4,308 over 12 months
Eden's all-in pricing includes a mandatory $99 per month membership that covers the provider visit, medication, and ongoing support. Peak Wellness, Embody, and Found bill monthly with no membership. Found offers both month-to-month cash and a 12-month prepaid option; the prepaid rate varies and should be confirmed at checkout.
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Plan length, billing structure, and refund terms
TrimRx bills multi-month plans as single upfront charges. A 6-month semaglutide plan costs $1,268 paid at signup; a 12-month plan costs $2,218 paid at signup. Those prepaid packages "will not be refunded for unused medication or remaining months" if you cancel early. TrimRx states that cancellation stops future charges only, meaning the upfront payment is final once billed. Third-party financing through Klarna, Afterpay, or Affirm is available, but TrimRx notes it is not a party to those agreements—terms and approval rest with the financing provider.
PlexusDx bills multi-month commitments as recurring monthly charges rather than lump sums. A 6-month plan at $149 per month means $149 is charged each month for six consecutive months, and that rate continues if you stay enrolled beyond the initial commitment. You pay $149 in month one, $149 in month two, and so on. This structure spreads cash flow and avoids a large upfront outlay, but PlexusDx does not offer a 12-month plan—its longest commitment is six months.
Eden, Peak Wellness, and Embody bill monthly with no multi-month discount or prepayment option captured in our July 2026 research. Found offers both month-to-month cash and a 12-month prepaid plan; the prepaid option reduces the effective monthly rate but requires full payment upfront.
Medication format and dose-agnostic pricing
TrimRx and all the alternatives in this comparison offer compounded semaglutide and tirzepatide injections. Neither TrimRx nor PlexusDx charges more when a clinician increases your dose; the monthly rate remains the same whether you are prescribed 0.25 mg or 2.4 mg of semaglutide. That dose-agnostic pricing is standard across most telehealth GLP-1 providers and protects you from surprise increases mid-treatment.
PlexusDx also offers oral semaglutide capsules ($289/month month-to-month, $269/month on a 3-month plan, $249/month on a 6-month plan) and oral tirzepatide capsules ($349/month month-to-month, $299/month on a 3-month plan, $279/month on a 6-month plan). TrimRx, Eden, Peak Wellness, Embody, and Found offer injections only in the plans we verified. If you prefer to avoid needles, PlexusDx's oral routes are the only verified option in this comparison; confirm availability and appropriateness with a licensed clinician during intake.
Service model and included support
TrimRx includes doctor consultations and shipping in its monthly rate and charges no separate membership fee. The website does not specify whether follow-up consultations are asynchronous messaging or scheduled video visits, and we did not capture service-model details beyond "doctor consultations included."
PlexusDx includes an initial provider consultation, ongoing asynchronous messaging with a licensed clinical team, and a named PharmD check-in as part of every plan. No membership fee is charged, and shipping is included. PlexusDx also offers an optional genetic testing add-on that analyzes how your genetics may influence medication response, but that add-on is not required to enroll.
Eden's $198 semaglutide rate and $298 tirzepatide rate are all-inclusive figures that bundle a required $99 per month membership with medication. That membership covers the provider visit, prescription, medication, and ongoing support; there is no standalone medication-only rate.
Peak Wellness, Embody, and Found each include provider consultations and shipping in their monthly rates with no separate membership fee captured in our research.
Strengths and limitations across alternatives
TrimRx strengths
-
Lowest prepaid per-month rate for semaglutide: the 12-month plan at $184.83 per month (our calculation, $2,218 total) beats every other verified option when measured as a per-month figure.
-
Dose-agnostic pricing: the rate does not increase when your clinician raises your dose.
-
No membership fee: the monthly charge is all-in for medication, consultations, and shipping.
TrimRx limitations
-
Advertised-vs-checkout pricing gap: the website advertises $199 semaglutide and $299–$349 tirzepatide, but verified checkout charged $299 and $399 month-to-month on July 18, 2026.
-
Upfront payment for multi-month plans: 3-month, 6-month, and 12-month plans are billed as single charges—$2,218 upfront for a 12-month semaglutide plan.
-
No refund for unused months: if you stop treatment early, the prepaid total is not refunded.
-
Highest month-to-month rate in this comparison: $299 semaglutide and $399 tirzepatide month-to-month are more expensive than every alternative except Found's tirzepatide cash rate.
PlexusDx strengths
-
Lowest month-to-month rates: $189 semaglutide and $289 tirzepatide beat every verified alternative on flexible, no-commitment pricing.
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Monthly billing on multi-month plans: the 6-month rate of $149 semaglutide is charged $149 per month, not $894 upfront, which eases cash flow.
-
Lowest verified 12-month cost for semaglutide injection: $1,788 over 12 months on the 6-month plan, $430 less than TrimRx's 12-month prepaid total.
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Oral semaglutide and tirzepatide options: the only provider in this comparison with verified needle-free routes.
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Named PharmD check-in: a licensed pharmacist reviews your case as part of standard care.
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Trustpilot rating: PlexusDx holds a 4.3-star rating on Trustpilot, with 79% of reviews at five stars and 83% at four stars or higher (captured September 9, 2026; trustpilot.com/review/plexusdx.com).
PlexusDx limitations
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No 12-month plan: the longest commitment is six months, so you cannot lock a single rate for a full year.
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Higher per-month rate than TrimRx's 12-month prepaid: PlexusDx's best rate ($149/month on a 6-month plan) is $35.83 per month more than TrimRx's 12-month prepaid rate, though PlexusDx's 12-month total is still lower because TrimRx's calculation assumes prepayment.
Eden, Peak Wellness, Embody, and Found
Eden's all-in rate of $198 semaglutide and $298 tirzepatide is competitive with PlexusDx when the required membership is included. Peak Wellness at $249 semaglutide sits between PlexusDx's month-to-month and TrimRx's checkout rate. Embody matches TrimRx's verified checkout rate for semaglutide ($299) and undercuts it for tirzepatide ($349 vs $399). Found's month-to-month cash rates are higher than PlexusDx but lower than TrimRx's checkout prices; Found's 12-month prepaid option (from $2,028 over 12 months) is competitive with PlexusDx's 6-month plan and should be confirmed at checkout for current terms.
Choose TrimRx if…
- You are comfortable paying $2,218 upfront for a 12-month semaglutide supply and you are confident you will complete the full year without stopping early.
- You want the lowest per-month rate ($184.83 for semaglutide, our calculation) and you accept that the prepaid total is non-refundable.
- You have confirmed the actual checkout rate for your plan length and medication, not the advertised figure, and that rate fits your budget.
Choose Eden if…
- You want an all-in monthly rate that bundles membership, medication, and support with no separate line items.
- The $198 semaglutide or $298 tirzepatide all-in figure (which includes the required $99/month membership) aligns with your budget and you value the bundled support model.
Choose Peak Wellness if…
- You want a $249/month semaglutide rate with no membership and no multi-month commitment.
- You prefer a mid-tier price point that undercuts TrimRx's month-to-month checkout rate and Embody's rate but sits above PlexusDx's month-to-month and Eden's all-in figure.
Choose Embody if…
- You want $299 semaglutide or $349 tirzepatide with dose-agnostic pricing and no membership.
- You are comfortable with month-to-month billing and you do not need a multi-month discount or prepaid option.
Choose Found if…
- You want the flexibility of month-to-month cash ($289 semaglutide, $359 tirzepatide) or the option to prepay 12 months at a reduced rate.
- You value Found's coaching and behavioral support model alongside medication.
Choose PlexusDx if…
- You want the lowest verified month-to-month rates ($189 semaglutide, $289 tirzepatide) with no prepayment and the flexibility to cancel anytime.
- You want the lowest verified 12-month total cost for semaglutide injection ($1,788 on the 6-month plan) while keeping monthly payments low and predictable.
- You prefer monthly billing over lump-sum prepayment, even on multi-month commitments.
- You want the option of oral semaglutide or tirzepatide capsules instead of injections, or you want to explore a microdose GLP-1 maintenance protocol ($129/month) after initial weight loss.
- You value a named PharmD check-in and optional genetic testing as part of your care plan.
- You want to work with a provider that holds a verified 4.3-star Trustpilot rating with 83% of reviews at four stars or higher.
Methodology and freshness
We captured TrimRx checkout pricing on July 18, 2026, by completing a full signup flow and recording the rates displayed at checkout. We compared those figures against advertised rates on the TrimRx website captured the same day. PlexusDx pricing was verified on July 18, 2026, via the public product pages and checkout flow. Eden, Peak Wellness, Embody, and Found pricing were captured between July 17 and July 23, 2026, from each provider's checkout or marketing pages. All 12-month cost calculations are our own, derived by multiplying monthly rates by 12 or by calculating the number of prepaid cycles required to cover 12 months. Per-month rates for prepaid plans are calculated by dividing the total prepaid amount by the number of months covered; these rates are labeled our calculation throughout. We did not test clinical outcomes, medication quality, or customer support responsiveness. No provider paid for inclusion, and PlexusDx applies the same evidence rules to its own program and competing programs. Pricing, plan terms, and medication availability may change; confirm all figures at checkout before purchase.
Frequently Asked Questions
Why does TrimRx advertise $199 semaglutide but charge $299 at checkout?
TrimRx's homepage and marketing materials display $199 per month for semaglutide and figures between $299 and $349 for tirzepatide. When we completed a full signup flow on July 18, 2026, the checkout screen charged $299 per month for semaglutide and $399 per month for tirzepatide on the month-to-month plan. Neither advertised figure appeared. This discrepancy may reflect promotional intent, outdated pricing, or plan-specific conditions not visible until checkout. Always confirm the actual rate at checkout before committing to any plan length.
Is PlexusDx's 6-month plan billed upfront like TrimRx's plans?
No. PlexusDx bills multi-month plans as recurring monthly charges, not lump sums. A 6-month semaglutide plan at $149 per month means $149 is charged each month for six consecutive months. TrimRx's 6-month semaglutide plan costs $1,268 paid upfront as a single charge. PlexusDx's monthly billing spreads cash flow and avoids a large upfront payment, but you commit to six months of recurring charges when you enroll.
Can I get a refund from TrimRx if I stop treatment early on a prepaid plan?
No. TrimRx states that multi-month packages "will not be refunded for unused medication or remaining months." Cancellation stops future charges only. If you prepay $2,218 for a 12-month semaglutide plan and stop after four months, the remaining $1,479 (our calculation: eight months at $184.83 per month rate) is not refunded. If you are uncertain about completing a full prepaid term, a month-to-month or monthly-billed multi-month plan from another provider may better fit your situation.
Does PlexusDx offer oral GLP-1 medications, and how much do they cost?
Yes. PlexusDx offers compounded oral semaglutide capsules at $289 per month month-to-month, $269 per month on a 3-month plan, and $249 per month on a 6-month plan. Compounded oral tirzepatide capsules cost $349 per month month-to-month, $299 per month on a 3-month plan, and $279 per month on a 6-month plan. A licensed clinician determines whether oral formulations are appropriate for you during the intake process. Oral options are not available from TrimRx, Eden, Peak Wellness, Embody, or Found in the plans we verified.
Which provider has the lowest total cost for semaglutide over 12 months?
PlexusDx delivers the lowest verified 12-month total cost for semaglutide injection: $1,788 over 12 months on the 6-month plan ($149 per month billed monthly). TrimRx's 12-month prepaid plan costs $2,218 total, $430 more than PlexusDx. TrimRx's per-month rate ($184.83, our calculation) is lower than PlexusDx's $149 rate, but the total outlay over 12 months is higher because TrimRx requires full prepayment and PlexusDx bills monthly. Found's 12-month prepaid option starts at $2,028 (captured July 17–23, 2026) and should be confirmed at checkout for current terms.
Sources
- TrimRx checkout capture and advertised pricing, July 18, 2026
- PlexusDx product pages and checkout, July 18, 2026
- Eden, Peak Wellness, Embody, and Found checkout and marketing pages, July 17–23, 2026
- PlexusDx Trustpilot profile, September 9, 2026 (trustpilot.com/review/plexusdx.com)
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Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.
Medical and Editorial Standards
Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.
Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.
Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.
Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.
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