Last updated: September 22, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance.

This article is part of the PlexusDx Education Hub — evidence-based guidance on GLP-1 therapies and weight-management care. Browse all Peptides & GLP-1 education

Editorial note: PlexusDx publishes this editorial review and offers one of the programs discussed. PlexusDx is not affiliated with MEDVi and has no commercial relationship with the companies named in this article; there are no affiliate links. Information is based on the sources and dates shown.

The MEDVi vs Ro question comes down to two different billing models. MEDVi sells compounded semaglutide injections with medication included: $179 for the first month (new patients), then $299 per billing cycle at refill as displayed September 22, 2026. Ro sells branded medication only, with a $149/mo Body membership billed separately from the drug; Ro's Zepbound® KwikPen starts at $299/mo on top of that membership. If you want compounded medication in one charge, MEDVi is the closer fit. If you want branded Wegovy® or Zepbound® through telehealth, Ro is built for that. PlexusDx offers a third route: compounded medication at one flat monthly price with no membership.

Program model and current menu

MEDVi is a telehealth platform whose prescriptions are issued by licensed providers in its network. Its compounded menu, as listed on MEDVi's program page on September 22, 2026, includes compounded semaglutide injection, compounded tirzepatide injection, and a daily dissolvable compounded semaglutide tablet. MEDVi also lists branded Wegovy® pill, Wegovy® injection, and Zepbound® injection through a separate membership-plus-medication pathway, with availability "subject to change."

Ro's weight-loss program, as shown on Ro's official page the same day, is branded only: Wegovy® pill, Wegovy® pen, and Zepbound® KwikPen. Compounded semaglutide or tirzepatide is not offered on the page we checked. So a ro vs medvi comparison is partly a compounded-versus-branded decision, and the two products are not interchangeable. Compounded semaglutide and tirzepatide are not FDA-approved drug products and are not the same as Wegovy®, Ozempic®, Zepbound® or Mounjaro®. The FDA explains its position on unapproved GLP-1 drugs.

Membership versus medication charges

This is where the monthly numbers stop being comparable at face value. MEDVi's compounded programs state that "Medication is included in the cost of the MEDVi Program" and describe "No membership or hidden fees." Ro's membership covers the clinical relationship; the medication is a second, separate charge that depends on the drug and dose tier.

PlexusDx publishes this comparison and offers one of the programs discussed. Information is based on the sources and dates shown.

Item MEDVi Ro Checked
Membership fee None on compounded programs (per MEDVi); branded pathway uses a monthly membership plus medication cost $149/mo recurring ($39 first month; $74/mo on Ro's 12-month plan paid in advance) Sept 22, 2026
Compounded semaglutide injection $179 first month (new patients); $299 per cycle refill as displayed Not offered on page Sept 22, 2026
Compounded tirzepatide injection $399 per cycle ongoing month-to-month (MEDVi's rate, verified September 22, 2026); first-month offer shown after the questionnaire — confirm in MEDVi's official offer Not offered on page Sept 22, 2026
Branded Zepbound® (lowest tier) Membership + medication cost; amount not shown $299/mo medication + $149/mo membership Sept 22, 2026
Branded Wegovy® pill (lowest tier) Membership + medication cost; amount not shown $149/mo medication + $149/mo membership Sept 22, 2026

Checked September 22, 2026 from each provider's official pages. MEDVi's ongoing month-to-month rates ($299 semaglutide, $399 tirzepatide) were verified September 22, 2026; confirm current pricing in MEDVi's official offer. Ro's medication prices are dose-tiered; the lowest tier is shown. Ro bills membership and medication as two separate charges.

Compare PlexusDx plans

PlexusDx Weight Management Protocols: compounded semaglutide injection from $189/mo and tirzepatide injection from $289/mo month-to-month, all-inclusive (provider visit, prescription, medication, shipping). No membership fee. Flat price at every dose.

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Branded and compounded access where offered

Ro publishes dose-tiered branded prices: Wegovy® pill at $149, $199 or $299 per month by dose; Wegovy® pen at $349; Zepbound® KwikPen at $299, $399 or $449 per month by dose. Each is in addition to the $149/mo membership. Ro's medication prices therefore rise as dose rises.

MEDVi's compounded programs advertise the "Same fair price at every dose." Its branded pathway is priced as a monthly membership plus the medication cost; the medication amount is not shown on the program page. MEDVi's ongoing month-to-month rate for compounded tirzepatide injection is $399, verified September 22, 2026; MEDVi shows its tirzepatide first-month offer after the questionnaire, so confirm it in the official offer. MEDVi's oral tablet runs about $70 a month over its injection rate for the same compound (read on its plan-selection screen); MEDVi does not publish a tablet total on its public page. For the full MEDVi price picture, see MEDVi Cost: Semaglutide, Tirzepatide, Membership, and Plan Prices.

Insurance and cash-pay pathways

Both providers publish self-pay prices. MEDVi's start page states "no insurance required" and lists HSA/FSA acceptance. Ro's published branded prices are self-pay medication prices billed alongside the membership. Neither pricing page we checked on September 22, 2026 describes an insurance-assistance or prior-authorization service, so if coverage matters to you, ask each provider directly before enrolling. Do not treat a membership fee as medication coverage; it is a service charge.

Support and renewal

MEDVi lists physician review, a personalized plan, 1:1 guidance, a metabolic report, "Free dietician visits & care coaching," "Unlimited 24/7 support," and free shipping as included. Its cancellation and refund policy asks for a cancellation request at least 72 hours before the next billing date, states that no refund is issued for the month in which cancellation occurs, and says a full refund applies only within the first 72 hours without services or on medical disqualification. MEDVi's billing-cycle length is not published, so treat each charge as "per billing cycle."

Ro requires cancellation 48 hours before renewal, and its membership fee is non-refundable once paid. Publicly posted MEDVi customer reviews on third-party sites describe a range of billing and support experiences; those are self-reported and not verified here.

Choosing a pathway

Choose MEDVi if you want compounded semaglutide with medication, coaching and shipping in one charge, and you are comfortable with its ongoing rates ($299 per cycle for semaglutide, $399 for tirzepatide, verified September 22, 2026) and confirming the tirzepatide first-month offer inside its offer. Choose Ro if you specifically want an FDA-approved branded product and accept a separate recurring membership plus dose-tiered medication pricing. Either way, your prescribing clinician decides whether a medication is appropriate; neither platform guarantees a prescription.

Where PlexusDx fits

PlexusDx offers compounded medication through an independent network of U.S.-licensed clinicians on a state-licensed telehealth platform, prepared by state-licensed 503A compounding pharmacies. PlexusDx Semaglutide Injection is $189/mo month-to-month and PlexusDx Tirzepatide Injection is $289/mo month-to-month, versus MEDVi's ongoing month-to-month $299 and $399 (verified September 22, 2026), $110 a month less at PlexusDx on either compound. One monthly price covers the provider visit, prescription, medication and shipping; there is no membership fee; the price is flat across every dose level; you pay $0 until your provider approves a prescription; and month-to-month plans cancel anytime. Compare current plans on the Weight Management Protocols collection, or read the full MEDVi vs PlexusDx comparison.

A note on genetics (optional)

PlexusDx offers compounded semaglutide and tirzepatide through its Weight Management Protocols. Separately, and only if it interests you, the GLP-1 & Peptide Pathways Genetic Test ($298) analyzes 14 pathways, 49 peptides, 150+ genetic insights, including variants in FTO, MC4R and TCF7L2 that relate to appetite and glucose-handling pathways. It does not predict how you will respond to any medication and does not tell you which drug, dose or provider is right for you; it is context for a conversation with your clinician. Test before you invest, and treat genetics as a guide, not a guarantee.

This article is educational. PlexusDx is not affiliated with MEDVi and has no commercial relationship with the companies discussed. PlexusDx offers compounded semaglutide and tirzepatide through its own Weight Management Protocols; this article compares approaches in the GLP-1 telehealth space. The GLP-1 & Peptide Pathways Genetic Test analyzes how your genes influence peptide-related biological pathways. It does not predict response to any specific medication and does not recommend, prescribe, or determine which peptides you should use. Consult a qualified healthcare provider before beginning any peptide protocol. Compounded semaglutide and tirzepatide are not FDA-approved drug products; they are prepared by state-licensed compounding pharmacies under federal compounding rules and are not the same as Wegovy®, Ozempic®, Zepbound® or Mounjaro®. Zepbound® and Mounjaro® are registered trademarks of Eli Lilly and Company; Wegovy® and Ozempic® are registered trademarks of Novo Nordisk A/S. PlexusDx is not affiliated with or endorsed by either company.

Frequently Asked Questions

Does MEDVi or Ro charge a membership fee?

Ro charges a $149 per month Body membership, billed separately from medication, with a $39 first month. MEDVi says its compounded programs include medication in the program price with no membership fee. MEDVi's branded Wegovy and Zepbound pathway is different: it is priced as a monthly membership plus the medication cost, billed separately, as of September 22, 2026.

Is MEDVi cheaper than Ro for semaglutide?

They sell different products, so a single ranking is misleading. MEDVi's compounded semaglutide injection is $179 for the first month, then $299 per billing cycle as displayed September 22, 2026, with medication included. Ro sells branded Wegovy only, from $149 per month for the pill plus a $149 monthly membership. Compounded and branded products are not interchangeable.

Does Ro offer compounded semaglutide or tirzepatide?

Not on the weight-loss page we checked September 22, 2026. Ro's published lineup is branded Wegovy pill, Wegovy pen and Zepbound KwikPen, with dose-tiered medication prices billed in addition to the membership. If you specifically want a compounded injection, MEDVi or a flat-rate program such as PlexusDx is the more direct comparison.

How do cancellation terms compare between MEDVi and Ro?

MEDVi asks for a cancellation request at least 72 hours before the next billing date and does not refund the month in which you cancel; a full refund applies only within the first 72 hours without services or on medical disqualification. Ro requires cancellation 48 hours before renewal, and its membership fee is non-refundable once paid. Read each current policy before enrolling.

Does either program guarantee a prescription?

No. On both platforms a licensed provider reviews your intake and decides whether a medication is appropriate. MEDVi's prescriptions are issued by licensed providers in its network; Ro routes through its own clinicians. Paying a membership fee or a first-month price does not guarantee approval, and treatment decisions belong to the prescribing clinician, not the platform.

Sources and dates checked

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This article is part of the PlexusDx Education Hub. Browse all Peptides & GLP-1 education

Medical and Editorial Standards

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. Sources and the dates they were checked are listed at the end of the article.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services, and offers compounded GLP-1 programs through its Weight Management Protocols. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

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