Last reviewed: May 12, 2026
Last updated: May 12, 2026
Written by:
Jay Hastings
,
CEO of PlexusDx
Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.
Medically reviewed by:
Jayden Lee, PharmD, EMBA
Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.
This article is part of the PlexusDx Education Hub — your resource for evidence-based guidance on GLP-1 therapies, weight management protocols, and the genetic variables that shape every metabolic decision. Browse all Peptides & GLP-1 education
This is an independent editorial review. PlexusDx has no commercial relationship with Medvi or Fridays, and no affiliate links or paid placements appear on this page.
Full head-to-head: PlexusDx vs Fridays →
Full head-to-head: PlexusDx vs MEDVi →
Fridays is one of the few GLP-1 telehealth programs that posts month-to-month rates publicly, which makes a Medvi comparison mostly a pricing-structure exercise. This review starts with what Fridays actually advertises, then works through how the two programs bill, before turning to the one input no rate card captures. As of April 2026, both sit among dozens of options in the weight-management market.
Start your GLP-1 program with PlexusDx
One all-inclusive price covers your online provider visit, prescription, compounded medication, and shipping — no membership, no hidden fees. Complete a short intake and a licensed provider takes it from there.
Start your intake →
Fridays' published rates at a glance
As of Fridays' own pricing page (joinfridays.com/pricing, verified 2026-07-20), Fridays advertises compounded semaglutide at $249/mo and compounded tirzepatide at $359/mo as ongoing month-to-month rates, with $0 membership, free shipping, and included coaching and dietitian support. Prepaid multi-month bundles lower the per-month equivalent — a paid-annually plan works out to roughly $150/mo for semaglutide and $240/mo for tirzepatide. See Fridays' official website for current terms.
How Medvi structures its program
Medvi (Medvi Wellness) runs a telehealth-plus-compounded-pharmacy model: virtual evaluation, provider-issued prescription, and dispensing of either brand-name FDA-approved GLP-1 therapy or compounded semaglutide and tirzepatide through licensed compounding pathways. Its posted terms live on Medvi's official website. Because pricing in this category moves quickly — Fridays' own rates shifted materially within a single day — the current figure on each brand's pricing page is the only one worth acting on.
Month-to-month versus prepaid bundles
The structural lesson from Fridays' card applies across the category: a headline rate depends heavily on whether you pay monthly or commit up front. For reference, PlexusDx's month-to-month rates run roughly $60—$70/mo below Fridays' advertised month-to-month for both compounds, and Fridays also sells prepaid 3- and 6-month bundles. Which option costs less for you depends entirely on how long you plan to stay on the protocol and how much you are willing to prepay before you have even confirmed the medication suits you.
Same molecules, different storefronts
Whatever the price tag, the pharmacology is fixed. GLP-1 receptor agonists (semaglutide, liraglutide, dulaglutide) and the GIP/GLP-1 dual agonist tirzepatide act on satiety, appetite regulation, and gastric emptying, with a trial record spanning STEP (semaglutide, NEJM 2021), SURMOUNT (tirzepatide, NEJM 2022), and SURMOUNT-OSA (tirzepatide for obstructive sleep apnea, NEJM 2024). A lower monthly rate does not buy a different molecule; it buys a different way of paying for the same one, so price should be read as a billing choice rather than a clinical one.
The variable no rate card shows
Price pages say nothing about your metabolic baseline. Variants in FTO, GLP1R (the target of every GLP-1 compound), MC4R, and TCF7L2 shape appetite, satiety, and glucose handling before any prescription is written. They are pathway-level markers — not predictors of a specific drug response, but real context for the decision. The PlexusDx Precision Peptide Genetic Test reads 14 pathways, 49 peptides, 150+ genetic insights across those genes, so the lowest-priced plan is not the only thing you weigh.
Comparing the PlexusDx approach
PlexusDx offers semaglutide and tirzepatide through its Weight Management Protocols — Semaglutide Injection, Semaglutide Oral, Tirzepatide Injection, and Tirzepatide Oral — with the genetic read layered on top. That "test before you invest" step is the part a rate card cannot quote.
Not affiliated: PlexusDx has no commercial ties to Medvi or Fridays and received no compensation for this review.
Related reading on PlexusDx: GLP 1 Drugs, GLP 1 Hormone, What Is GLP 1, GLP 1 What Is.
Disclaimer: This article is educational. PlexusDx is not affiliated with Medvi or Fridays and has no commercial relationship with the companies reviewed. PlexusDx offers semaglutide and tirzepatide through its own Weight Management Protocols. The Precision Peptide Genetic Test analyzes how your genes influence peptide-related biological pathways — it does not predict response to any specific medication. Consult a qualified healthcare provider before beginning any peptide protocol.
Frequently Asked Questions
How much does Fridays cost per month?
As of the verified pricing snapshot, Fridays advertises compounded semaglutide at $249/mo and tirzepatide at $359/mo month-to-month, with $0 membership and free shipping. Paid-annually bundles work out to roughly $150 and $240 per month, alongside the advertised $249 and $359 month-to-month rates. Rates in this category change quickly, so confirm on Fridays' page.
Is month-to-month or a prepaid bundle lower cost?
It depends on your timeline. PlexusDx month-to-month runs below Fridays' month-to-month, and both offer prepaid multi-month bundles for people who prefer to commit up front. Which route costs less hinges on how long you plan to stay on the protocol.
Does a cheaper plan mean a different medication?
No. Pricing reflects the business model, not the molecule. Compounded semaglutide or tirzepatide works through the same pharmacology regardless of which program dispenses it or what the monthly rate happens to be. A lower price buys a different payment structure, not different biology.
What does the genetic test add to a pricing decision?
It shifts the question from "lowest-priced plan" to "informed plan." By mapping pathway-level variants in FTO, MC4R, and TCF7L2, the Precision Peptide Genetic Test gives you baseline context to discuss with a provider alongside cost — something no rate card provides.
This article is part of the PlexusDx Education Hub. Browse all Peptides & GLP-1 education
Medical and Editorial Standards
Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.
Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.
Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.
Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.
Share:
Noom vs Medvi: Behavioral App Versus Medication Program
Hims vs Medvi: How the Two GLP-1 Programs Are Built