Fridays GLP-1 vs PlexusDx: tirzepatide and semaglutide cost (2026)
PlexusDx tirzepatide costs less than Fridays' advertised and checkout prices at every plan length: $189 vs $359 a month on Oct 21, 2026. PlexusDx also offers a free 15-minute PharmD consult and sells at-home genetic and blood tests separately.
Fridays reviews: 4.1/5 on Trustpilot (5,058 reviews) · F from the BBB
| Checkout price | PlexusDx | Fridays |
|---|---|---|
| Tirzepatide month to month | $189/mo | $359/mo |
| Tirzepatide 12-month plan | $129/mo $1,548 up front | $215/mo |
| Semaglutide month to month | $149/mo | $249/mo |
| Semaglutide 12-month plan | $99/mo $1,188 up front | $133/mo |
- When you're charged
- PlexusDx: When your prescription goes to the pharmacy
- Fridays: When you submit your intake for provider review
- Refunds
- PlexusDx: Full refund until it reaches the pharmacy
- Fridays: Full refund only if a provider finds you not eligible; other fees are non-refundable
- Lab work
- PlexusDx: At-home blood tests, sold separately
- Fridays: Covered by your subscription, at a Quest location
- Same at both
- Live chat support · No separate membership fee
What else PlexusDx offers
GLP-1 & Peptide Pathways Genetic Test
150+ genetic insights across 14 health pathways.
$298, or $99 for program members.
See the test →At-home blood tests from $129
Plus supplement packs from $79, built from your results.
See blood tests →The GLP-1 & Peptide Pathways Genetic Test does not select or predict a medication; your provider decides.
What do Fridays' reviews say?
Fridays' reviews split by platform: 78% of its Trustpilot reviews give five stars, while the BBB rates its operator, Thrive Health Group, F.
Trustpilot
78% five-star · 10% one-star
- Replies to 100% of negative reviews, usually within 48 hours.
- Asks customers to review.
BBB
F, not accredited
- Listed under Thrive Health Group Inc, with JoinFridays.com and Fridays as other names.
- 74 complaints in the past 3 years, 67 in the past 12 months; 65 had no response from the business.
- Complaints on its first page are mostly about prepaid months not shipped, shipping delays and refunds after cancelling.
Both read at source on Oct 21, 2026. Ratings belong to the platforms, not to PlexusDx.
What do Fridays and PlexusDx cost on 3- and 6-month plans?
PlexusDx costs less on 3- and 6-month plans too: tirzepatide is $169 and $149 a month against Fridays' $224 and $242.
| Plan | PlexusDx | Fridays |
|---|---|---|
| Tirzepatide 3-month plan | $169/mo $507 up front | $224/mo |
| Tirzepatide 6-month plan | $149/mo $894 up front | $242/mo |
| Semaglutide 3-month plan | $129/mo $387 up front | $149/mo |
| Semaglutide 6-month plan | $109/mo $654 up front | $158/mo |
Is Fridays or PlexusDx better?
PlexusDx is better on checkout price at every plan length, and its blood tests are done at home with no lab visit; Fridays is better if you want coaching and a dietitian included, or a branded medication.
Choose Fridays if…
- You want nutrition and mental-health coaching, a dietitian and unlimited provider visits included.
- You want lab tests covered by your subscription and can visit a Quest location.
- You want a branded medication such as Ozempic®, Zepbound® or Wegovy®, which Fridays' pricing page also lists.
Choose PlexusDx if…
- You want the lower checkout price at every plan length, microdose included.
- You want your card charged only once your prescription is sent to the pharmacy.
- You want a free 15-minute consult with Dr. Jayden Lee, PharmD, by video or phone.
- You want at-home blood tests and a genetic test, sold separately, with no lab visit.
How do Fridays and PlexusDx compare on cancelling, formats and payment?
Both renew automatically until you cancel.
Read on Oct 21, 2026 from each company's own pages.
- Cancelling
- PlexusDx: Turn off renewal in your patient portal before the next charge
- Fridays: By email or in your account at least 72 hours before your next billing date
- Formats
- PlexusDx: Injection, including a microdose program
- Fridays: Compounded injection and a GLP-1 microdosing program in the sign-up we walked; its pricing page also lists branded Ozempic®, Zepbound® and Wegovy® plans
- Same at both
- Pay over time with Klarna · HSA and FSA cards · LegitScript seal
How does compounded GLP-1 telehealth work?
You complete an online intake, a licensed provider reviews it, and if treatment is appropriate a state-licensed 503A pharmacy prepares and ships your medication, with no in-person visit.
Both PlexusDx and Fridays start with an online intake and a licensed U.S. provider's review. In the PlexusDx program, a 503A compounding pharmacy, a state-licensed facility that prepares medication for one patient from a valid prescription, fills the prescription and ships it to your door.
Compounded medications are not FDA-approved and are not reviewed by the FDA for safety, quality, or effectiveness. They are a legal, provider-prescribed option prepared by a licensed pharmacy, not a generic or a substitute the FDA has evaluated.
How did we check these prices and reviews?
We walked Fridays' sign-up to the plan choice at its checkout for every plan on Oct 21, 2026, without paying, and read its pricing page, Terms, Trustpilot and BBB pages the same day.
We recorded every plan length for both drugs and the microdose program. The tables show each company's checkout price; for 3-, 6- and 12-month plans Fridays' checkout shows a price per month, not a total. PlexusDx prices come from our product pages on the same day.
Who wrote this. The PlexusDx editorial team wrote this page, and Dr. Jayden Lee, PharmD, reviewed it for accuracy.
Our bias. PlexusDx publishes this page and is one of the two programs compared. We show where Fridays is ahead, and we update the page when either company changes its prices.
Ready to start with PlexusDx?
PlexusDx semaglutide is $149 month to month or $99/mo on a 12-month plan; tirzepatide is $189 or $129/mo.
A licensed provider reviews your intake before anything is prescribed.
Start your online visitOr book a free 15-minute consult with Dr. Jayden Lee, PharmDFrequently Asked Questions
How much does Fridays tirzepatide cost?
Fridays' tirzepatide checkout price is $359 a month, or $224, $242 and $215 a month on 3-, 6- and 12-month plans. PlexusDx tirzepatide is $189 a month, or $129 a month on 12 months ($1,548 up front). Checked Oct 21, 2026.
How much does Fridays GLP-1 cost?
Fridays' semaglutide checkout price is $249 a month and tirzepatide is $359, or $133 and $215 a month on a 12-month plan. Its 3- and 6-month semaglutide plans are $149 and $158 a month. Checked Oct 21, 2026.
Does Fridays have a membership fee?
No separate membership fee on its compounded plans. Fridays' pricing page says "Membership included free." Its branded Wegovy® plans charge a separate membership, medication not included. PlexusDx has no membership fee.
Is Fridays cheaper than PlexusDx?
No. PlexusDx costs less than Fridays' checkout price at every plan length. Tirzepatide is $189 a month at PlexusDx against Fridays' $359, and semaglutide is $149 against $249.
Does Fridays have 12-month plans?
Yes. Fridays sells monthly, 3-, 6- and 12-month plans. On Oct 21, 2026 its checkout showed 12-month plans at $133 a month for semaglutide and $215 for tirzepatide. PlexusDx's 12-month plans are $99 and $129 a month ($1,188 and $1,548 up front), and both offer pay over time through Klarna.
Does Fridays offer GLP-1 microdosing?
Yes. Fridays sells a GLP-1 microdosing program with monthly, 3-, 6- and 12-month plans. On Oct 21, 2026 its checkout listed microdose tirzepatide at $198 a month and microdose semaglutide at $249, down to $122 and $142 a month on 12 months. PlexusDx's microdose is $99 a month, down to $69 on a 12-month plan, for semaglutide or tirzepatide.
When does Fridays charge your card?
When you submit your medical intake for provider review. Fridays' Terms say your subscription begins at that point, "at which time you will be charged for the first billing cycle." At PlexusDx, cards are charged once your prescription is sent to the pharmacy.
Can you get a refund from Fridays?
Only in limited cases. Fridays refunds the billing cycle in full if a provider finds you not eligible; its FAQ says this applies before services begin, which it defines as when your intake is submitted for review. Other fees are non-refundable, including if you cancel mid-cycle, and medication can't be returned once shipped. PlexusDx gives a full refund if you cancel after approval and before your prescription is sent to the pharmacy.
Is Fridays legit?
Fridays is an operating telehealth company whose reviews split by platform. As of Oct 21, 2026, Trustpilot rated Fridays Health 4.1 out of 5 ("Great") across 5,058 reviews, while the BBB rated its operator, Thrive Health Group, F and not accredited, with 74 complaints in three years, 65 of them not answered. Its site shows a LegitScript Certified badge and says clinical services are provided by OpenLoop Healthcare Partners, PC and other networks.
Is Fridays FDA approved?
Fridays is a telehealth company, so FDA approval doesn't apply to it; the compounded semaglutide and tirzepatide it offers are not FDA-approved. Its pricing page also lists branded Ozempic®, Zepbound® and Wegovy® plans, which are FDA-approved medications. Compounded medications prescribed through PlexusDx are not FDA-approved either.
What pharmacies does Fridays use?
Fridays' Terms name four partner pharmacies: Red Rock Compounding Pharmacy (Utah), Health Warehouse (Kentucky), Precision Medicine (New York) and Triad Rx (Alabama). In the PlexusDx program, licensed 503A pharmacies fill prescriptions.
Can I talk to a pharmacist?
Yes. PlexusDx offers a free 15-minute consult with Dr. Jayden Lee, PharmD, by video or phone. It is education and support; a licensed provider makes any prescribing decision.
What does the PlexusDx genetic test do?
The GLP-1 & Peptide Pathways Genetic Test shows how your genes relate to weight management and other peptide-related pathways, with 150+ genetic insights across 14 health pathways from one swab. It does not select or predict a medication; your provider decides. It costs $298, or $99 for program members, and is sold separately from any GLP-1 plan.
PlexusDx tells you about your biology. It does not tell you what to put in your body.
