Fridays vs PlexusDx: GLP-1 prices and programs compared
Part of our GLP-1 provider research: See how every compounded tirzepatide provider compares →
Month-to-month, PlexusDx charges $189 for semaglutide and $289 for tirzepatide — below the $249 and $359 Fridays advertises on its own pricing page. We also publish standing 3- and 6-month rates; Fridays publishes no standing multi-month per-month rate. Where Fridays clearly wins is support: every plan we captured includes unlimited provider visits, a dietitian and mental-health coaching.
Green marks the better result on that row, for either program.
Prices verified July 19–20, 2026 · Fridays figures from its pricing page, plan screens and captured checkout · semaglutide first, tirzepatide secondIs Fridays or PlexusDx better?
Month-to-month, PlexusDx costs less: $189/$289 versus the $249/$359 Fridays advertises. Fridays includes more support — unlimited provider visits, a dietitian and mental-health coaching on every plan we captured — and lists $0 lab fees alongside the bloodwork it requires.
This one is a genuine trade, and it splits on price against inclusions. On the monthly rate PlexusDx runs $60 to $70 under Fridays' advertised prices, and we publish standing 3- and 6-month rates where Fridays publishes an advertised annual option. On inclusions Fridays is ahead: it bundles unlimited provider visits, dietitian support and mental-health coaching into every plan and lists $0 lab fees alongside the bloodwork it requires, while PlexusDx adds a free pharmacist check-in, an optional genetics layer, published rates and no lock-in on the monthly plan.
- You want coaching built in. Every Fridays plan we captured bundles unlimited provider visits, 1-on-1 dietitian support, nutrition and mental-health coaching, and a care coach at no extra charge — a broader support package than PlexusDx includes, and the clearest thing Fridays does better than we do.
- You want bloodwork with no separate fees. Its pricing page lists $0 membership, $0 signup and $0 lab fees, and shipping was free at the checkout we captured. Fridays states that its required labs typically include a comprehensive metabolic panel, hemoglobin A1C, TSH and a lipid panel.
- You want the lower month-to-month price. $189/$289 as one flat, all-inclusive charge covering the consult, prescription, medication and shipping, $60 and $70 below the $249/$359 Fridays advertises month-to-month on its own pricing page.
- You want pricing that stays put. PlexusDx's rates are published, standing prices, and the monthly plan has no lock-in; Fridays' campaign landing page priced differently from joinfridays.com when we captured it on July 20, 2026.
- You want more formats. Semaglutide and tirzepatide injections, both orals, both GLP-Squared combinations, and a $129 microdose, seven in all, versus the two compounded programs in Fridays' captured flow. The orals cost more than the injections.
- You want a genetics option and pharmacist support. An optional genetics add-on ($298, or $99 for program members) and a free check-in with a Doctor of Pharmacy. The test doesn't select or predict a medication — your provider decides.
| Criterion | PlexusDx | Fridays |
|---|---|---|
| Month-to-month price ($189/$289 vs advertised $249/$359) | 5.0 | 3.0 |
| Multi-month commitment pricing (our published 3-/6-month rates vs its advertised annual option) | 4.0 | 2.5 |
| Price stability & transparency (published standing rates vs a campaign page that priced differently from its site) | 5.0 | 3.0 |
| Bundled coaching (unlimited provider visits + dietitian + mental-health coaching vs our PharmD check-in) | 3.0 | 5.0 |
| Membership & extra fees ($0 at both — a tie) | 5.0 | 5.0 |
| Formats & options (seven formats incl. oral & microdose vs the two captured compound programs) | 5.0 | 3.0 |
| Genetics & pharmacist support (optional DNA add-on + free PharmD check-in) | 4.5 | 3.0 |
Our own opinion scoring by the PlexusDx editorial team against each program's July 19–20, 2026 pricing and published offerings, not customer ratings. Fridays scores higher on bundled coaching; membership and extra fees are a tie at $0. We score higher on multi-month commitment pricing because we publish standing 3- and 6-month rates, while Fridays publishes an advertised annual option. We publish this comparison and are one of its two programs.
How much do Fridays and PlexusDx cost per month? (Verified July 2026)
PlexusDx is $189/month for semaglutide and $289 for tirzepatide month-to-month; Fridays advertises $249 and $359 on its own pricing page.
Month-to-month, the gap is $60 a month on semaglutide and $70 on tirzepatide against the rates Fridays advertises on its own pricing page. PlexusDx also publishes standing 3- and 6-month rates; Fridays publishes no standing multi-month per-month rate. What we publish below is Fridays' advertised month-to-month rate and its separate medication-only tier.
| Semaglutide — by term | PlexusDx | Fridays | Difference |
|---|---|---|---|
| Month-to-month | $189/mo, one all-inclusive charge | $249/mo — advertised, joinfridays.com/pricing, July 20, 2026 | PlexusDx −$60/mo |
| 3-month rate | $169/mo | No published standing multi-month rate | — |
| 6-month rate | $149/mo | No published standing multi-month rate | — |
| Checkout capture | Published rates — what you see is the rate | None reached for semaglutide in either session — its figure above is its advertised rate only | — |
| Tirzepatide — by term | PlexusDx | Fridays | Difference |
|---|---|---|---|
| Month-to-month | $289/mo, one all-inclusive charge | $359/mo — advertised, joinfridays.com/pricing, July 20, 2026 | PlexusDx −$70/mo |
| 3-month rate | $269/mo | No published standing multi-month rate | — |
| 6-month rate | $249/mo | No published standing multi-month rate | — |
Fridays' medication-only tier is a different product, not a cheaper version of the same one
Alongside its subscription plans, Fridays sells a medication-only option as a one-time purchase. Its own plan screens head that block "Medication Only (Excludes Savings & Support)" and spell out what you give up: "Forfeit: dedicated coaching, the companion app…" These prices buy medication alone. They exclude the coaching and support bundled into Fridays' subscription, so they are not like-for-like with the all-in monthly rates above, and we set no PlexusDx price against them. We list them because they are real, purchasable prices you may see on its plan screens.
| Fridays medication only — one-time purchase, coaching and support excluded | Semaglutide | Tirzepatide |
|---|---|---|
| 1-month supply | $279 one-time | $389 one-time |
| 3-month supply | $596 one-time | $896 one-time |
| 6-month supply | $1,050 one-time | $1,650 one-time |
| 12-month supply | $1,800 one-time | $2,880 one-time |
Fridays' medication-only prices, read from its plan-selection screens on July 19, 2026. Each is a single one-time purchase for medication alone, excluding the coaching and companion app that come with its subscription plans. They are not comparable to the all-inclusive monthly rates in the tables above, and no PlexusDx rate is compared against them.
How Fridays' pricing works, as captured
- Advertised month-to-month: $249 semaglutide and $359 tirzepatide on joinfridays.com/pricing (live-checked July 20, 2026), which also lists $0 membership, signup and lab fees.
- Its multi-month plans are prepaid: the one tirzepatide checkout we captured billed as a single upfront payment recurring every four months (captured checkout, July 20, 2026), not as a monthly charge.
- A separate medication-only tier is sold as a one-time purchase that excludes coaching and support — the prices in the table above.
- Shipping, refunds, cancellation: shipping was free at the captured checkout; Fridays commits to a full refund if its provider determines you're not eligible; its pricing page says you can cancel or pause anytime. Broader refund terms weren't captured.
- Semaglutide reached no checkout in either capture session — its month-to-month figure on this page is its advertised rate only.
Fridays figures: advertised month-to-month rates live-checked on joinfridays.com/pricing, July 20, 2026; medication-only prices from its plan-selection screens, July 19, 2026; billing cadence from one captured tirzepatide checkout, July 20, 2026.
PlexusDx figures: our own published all-inclusive rates, July 2026. Paired figures are semaglutide first, tirzepatide second. Prices change often — check both sites before deciding.
One flat monthly price, and it drops if you commit
Semaglutide $189/mo, tirzepatide $289/mo, all-inclusive — down to $149/$249 on a 6-month rate. A licensed provider reviews your intake before anything is prescribed.
How do PlexusDx and Fridays compare, feature by feature?
Both are cash-pay compounded-GLP-1 programs. Month-to-month, PlexusDx costs less; Fridays bundles more support — unlimited provider visits, a dietitian and mental-health coaching — and lists $0 lab fees.
| Feature | PlexusDx | Fridays |
|---|---|---|
| Month-to-month price | $189 / $289 | $249 / $359 — advertised, its pricing page, July 20, 2026 |
| Multi-month rates | $169–$149 / $269–$249 (3-/6-mo, published standing rates) | No published standing multi-month rate |
| Billing structure | One flat, all-inclusive monthly charge | Prepaid bundle — one payment recurring every 4 months (captured tirz checkout) |
| Medication-only option | No — every plan is all-inclusive | Yes — a one-time purchase excluding coaching and support (a different product; prices listed above) |
| Required membership fee | None ($0) | None ($0) — its own pricing page |
| Free shipping | Yes — included | Yes — free at the captured checkout |
| Price stability & lock-in | Published standing rates; no lock-in on the monthly plan | Campaign page priced differently from its site |
| Oral (no-injection) option | Yes — oral sema & tirz (a premium format) | No — injectable sema & tirz in the flow we captured (July 2026) |
| Combination GLP-1 protocol | Yes — GLP-Squared | No |
| Lower-cost microdose entry | Yes — $129/mo | No |
| Optional genetics add-on | Yes — $298, or $99 for members | No |
| Bundled human support | Free PharmD check-in | Unlimited provider visits · 1-on-1 dietitian · mental-health coaching |
| Free named-pharmacist check-in | Yes — Dr. Jayden Lee, PharmD | No — bundles dietitian & coaching instead |
Compiled from Fridays' pricing page, plan screens and one captured tirzepatide checkout (July 19–20, 2026), alongside PlexusDx's published rates. Fridays' semaglutide reached no checkout — its figures are advertised only. Paired cells: semaglutide first, tirzepatide second.
When is Fridays the better choice?
Fridays is the better pick if you want unlimited provider visits, dietitian and mental-health coaching bundled in, or bloodwork with no separate lab fee.
- Coaching is built in. Every Fridays plan we captured bundles unlimited provider visits, 1-on-1 dietitian support, nutrition and mental-health coaching, and a care coach — a broader bundled support package than PlexusDx includes, and the clearest thing Fridays does better than we do.
- Bloodwork with no separate fee. Fridays states its required labs typically include a comprehensive metabolic panel, hemoglobin A1C, TSH and a lipid panel, and its pricing page lists $0 membership, signup and lab fees. Shipping was free at the captured checkout.
- A medication-only option exists if you want the prescription without the coaching — a one-time purchase Fridays prices separately, and a different product from the all-inclusive plans compared here.
When is PlexusDx the better choice?
PlexusDx is the better pick if you want the lower month-to-month price, published rates that stay put with no prepay lock-in, more formats, or the genetics and pharmacist layer.
- The lower month-to-month price. $189 semaglutide and $289 tirzepatide as one flat, all-inclusive charge — $60 and $70 below the $249/$359 Fridays advertises month-to-month on its own pricing page.
- Pricing that stays put. PlexusDx's rates are published, standing prices, and the monthly plan has no lock-in; Fridays' campaign landing page priced differently from joinfridays.com when we captured it on July 20, 2026.
- More formats. Semaglutide and tirzepatide injections, both orals, both GLP-Squared combinations, and a $129 microdose — seven in all, versus the injectable sema and tirz in Fridays' captured flow.
- Genetics and a pharmacist. An optional genetics add-on ($298, or $99 for program members) and a free check-in with a Doctor of Pharmacy. The test doesn't select or predict a medication — your provider decides.
What does PlexusDx offer that Fridays doesn't?
PlexusDx offers formats Fridays' injectable program doesn't: oral semaglutide and tirzepatide, two combination protocols, and a $129 microdose. Fridays offers injectable sema and tirz with rich bundled coaching.
- Both cover the two main compounds. PlexusDx and Fridays each offer semaglutide and tirzepatide; month-to-month, PlexusDx's $189/$289 undercut Fridays' advertised $249/$359.
- Fridays' strength is bundled human support — unlimited provider visits, 1-on-1 dietitian and mental-health coaching on every plan we captured. That is a genuine advantage PlexusDx doesn't match.
- PlexusDx's strength is format choice — a no-injection oral route, the GLP-Squared combination, and a lower-cost $129 microdose entry that didn't appear in Fridays' captured flow.
PlexusDx GLP-1 formats and published pricing, month-to-month first
- Semaglutide injection — $189/mo month-to-month · $169 (3-mo) · $149 (6-mo)
- Tirzepatide injection — $289/mo month-to-month · $269 (3-mo) · $249 (6-mo)
- Oral semaglutide — $289/mo month-to-month · $269 (3-mo) · $249 (6-mo) — a no-injection format
- Oral tirzepatide — $349/mo month-to-month · $299 (3-mo) · $279 (6-mo)
- GLP-Squared combination protocol — $289/mo month-to-month · $249 (3-mo)
- GLP-Squared Oral combination protocol — $389/mo month-to-month · $369 (3-mo)
- Microdose GLP-1 — $129/mo flat, a lower-cost entry point
Fridays' captured flow (July 2026) offered injectable compounded semaglutide and tirzepatide, each advertised at $249/$359 month-to-month and bundling unlimited provider visits, 1-on-1 dietitian and mental-health coaching. PlexusDx formats show published month-to-month rates first.
How does Fridays' pricing work?
Fridays advertises $249 semaglutide and $359 tirzepatide month-to-month on its pricing page. Its 3- and 6-month plans are prepaid bundles, charged upfront as a single payment rather than billed monthly.
Every Fridays figure on this page carries a date and a surface, because its campaign landing page priced differently from joinfridays.com — so where a figure came from matters.
- The multi-month plans are prepaid. The one tirzepatide checkout we captured billed as a single upfront payment recurring every four months (captured checkout, July 20, 2026), not as a monthly charge.
- A separate medication-only tier is sold as a one-time purchase that excludes the coaching and companion app — a different product from the all-inclusive plans, and not comparable to them.
- $0 membership, free shipping, eligibility refund. Fridays lists no membership, signup or lab fees; shipping was free at checkout; it commits to a full refund if its provider determines you're not eligible, and its pricing page says you can cancel or pause anytime. Broader refund terms weren't captured.
- The "$425 value" is a claimed value of a bundled inclusion, not a fee. Fridays frames its included coaching as $425 of care; nobody is charged $425.
How does PlexusDx pricing work?
PlexusDx charges one flat, all-inclusive price per medication, the same at every dose — semaglutide $189/mo and tirzepatide $289/mo month-to-month, dropping to $149/$249 on a 6-month plan.
Where the two part ways is the month-to-month price and the structure behind it: PlexusDx's $189/$289 are published standing rates that sit $60–$70 below Fridays' advertised rates, and our monthly plan carries no lock-in. Fridays' multi-month plans are prepaid bundles — a single upfront charge on a four-month cycle, not a standing monthly rate.
Fridays figures: advertised month-to-month rates from joinfridays.com/pricing (July 20, 2026); billing cadence from one captured tirzepatide checkout (July 20, 2026); medication-only prices from its plan screens (July 19, 2026). PlexusDx: published all-inclusive rates, July 2026.
Does either program look at your biology or include pharmacist support?
Neither program includes a DNA-based test as part of its GLP-1 program. PlexusDx offers one as an optional add-on — $298, or $99 for program members.
First, credit where it's due: Fridays bundles unlimited provider visits, 1-on-1 dietitian support, and nutrition and mental-health coaching into every plan we captured — a broader human-support package than PlexusDx includes.
What PlexusDx adds is a layer neither program bundles — an optional look at your biology, and a pharmacist to talk it through.
- What it is: the optional Precision Peptide Genetic Test gives you and your licensed provider added clarity on how your body is wired — context to bring to your care, not a substitute for it.
- Price: $298, or $99 for program members — members receive a discount code about 10 days after their order.
- What it isn't: it does not select or predict a medication; your provider decides. It's context, not a prescription.
Every PlexusDx prescription includes a free 15-minute check-in with our Medical Director and Doctor of Pharmacy — by video or phone — for medication questions, side effects, and how your protocol is going. It's education and support; your licensed provider still makes every prescribing decision.
How did we verify these prices?
We took Fridays' month-to-month rates from its own pricing page on July 20, 2026, its medication-only prices from its plan-selection screens on July 19, and captured one tirzepatide checkout.
Method. Fridays' month-to-month rates come from joinfridays.com/pricing, live-checked July 20, 2026. One tirzepatide checkout captured on July 20 billed as a single prepaid payment recurring every four months. Its medication-only prices come from the plan-selection screens of July 19. Those captures are the source for every Fridays figure here; we used no third-party review site.
What we compare. We compare published regular rates. Promotional offers are common across this category — ours included — and they change too often to compare fairly, so we exclude them on both sides. Fridays' campaign landing page priced differently from joinfridays.com, and semaglutide reached no checkout at all, so its figure is advertised-only. Every Fridays number here is stamped with the date and the exact surface it came from.
A note on who wrote this. PlexusDx publishes this page and is one of the two programs compared, so we are not a neutral party. That's why we used Fridays' own pricing page and captured checkout as the only source for its figures, and why we state plainly where Fridays beats us — on bundled coaching and on lab fees. Category pricing changes often; check both sites before you decide.
- Fridays bundles richer human coaching. Every plan we captured includes unlimited provider visits, 1-on-1 dietitian support, and nutrition and mental-health coaching — a broader support package than PlexusDx includes.
- Fridays covers bloodwork with no separate fee. It states its required labs typically include a comprehensive metabolic panel, hemoglobin A1C, TSH and a lipid panel, and its pricing page lists $0 membership, signup and lab fees.
See your PlexusDx price. One flat, all-inclusive charge.
One published price covering the provider consult, prescription, medication and shipping — semaglutide $189/mo, tirzepatide $289/mo month-to-month, down to $149/$249 on a 6-month rate. A licensed provider reviews your intake before anything is prescribed.
Start your intakeFrequently Asked Questions
What is compounded GLP-1?
Compounded GLP-1 medications are semaglutide or tirzepatide prepared for an individual patient by a state-licensed 503A compounding pharmacy on a valid prescription. They are not FDA-approved. Both Fridays and PlexusDx operate in this category.
- Not FDA-reviewed. Compounded medications are not reviewed by the FDA for safety, quality, or effectiveness.
- The approved versions. Only Novo Nordisk (semaglutide) and Lilly (tirzepatide) make FDA-approved branded products.
Are compounded GLP-1 medications FDA-approved?
No — compounded medications are not FDA-approved and are not reviewed by the FDA for safety, quality, or effectiveness. They are prepared by a state-licensed 503A pharmacy for an individual patient on a valid prescription.
- Semaglutide. Novo Nordisk is the only U.S. company with FDA-approved semaglutide (Wegovy®, Ozempic®, Rybelsus®).
- Tirzepatide. Lilly is the only U.S. company with FDA-approved tirzepatide (Zepbound®, Mounjaro®).
Is PlexusDx cheaper than Fridays?
Month-to-month, yes: PlexusDx is $189/$289 versus the $249/$359 Fridays advertises on its own pricing page.
- Month-to-month, PlexusDx wins by $60–$70/month — $189 vs $249 (semaglutide) and $289 vs $359 (tirzepatide), the rates Fridays advertised on its pricing page on July 20, 2026.
- Its campaign landing page priced differently from its site, so check both before deciding.
How much does Fridays cost per month?
Fridays advertises $249/month for semaglutide and $359 for tirzepatide month-to-month on its own pricing page, checked July 2026.
- A separate medication-only tier is sold as a one-time purchase that excludes coaching and support — a different product, priced separately from the plans compared here.
- Semaglutide reached no checkout, so its figure is advertised only.
Does Fridays charge a membership fee?
No — Fridays charges no membership fee; its own pricing page lists $0 membership, signup and lab fees. Shipping was free at the checkout we captured, too.
- We verified $0 three ways — its pricing page, its own comparison table, and the absence of any membership line on the captured checkout.
- Neither program charges a membership. PlexusDx also has no membership fee; its price is one flat, all-inclusive charge.
How much does PlexusDx cost per month?
Month-to-month, PlexusDx is $189 for semaglutide and $289 for tirzepatide — one flat, all-inclusive charge covering the consult, prescription, medication and shipping. Rates drop to $149/$249 on a 6-month plan.
- The same at every dose — no dose surcharge, and no separate membership.
- Other formats: oral semaglutide ($289) and tirzepatide ($349), the GLP-Squared combination ($289), and a $129 microdose entry.
Can I cancel anytime, or am I locked into a contract?
PlexusDx's month-to-month plan has no contract — you can stop between refills — and Fridays' pricing page says you can cancel or pause anytime.
- PlexusDx's 3- and 6-month rates involve a longer commitment for a lower price; its longest plan is 6 months.
- Fridays' bundles are prepaid on a four-month cycle, so the upfront period is what you commit to; broader refund terms weren't captured.
Which program includes more coaching and support?
Fridays includes more bundled coaching — every plan we captured came with unlimited provider visits, 1-on-1 dietitian support, and mental-health coaching. PlexusDx includes a free pharmacist check-in instead.
- Fridays' bundled support is a genuine advantage PlexusDx doesn't match on the coaching side.
- PlexusDx adds a different layer — a free 15-minute check-in with Dr. Jayden Lee, PharmD, and an optional genetics add-on your provider can factor in.
What does the PlexusDx genetics test do?
It analyzes how your genes influence weight-management-related biological pathways, to inform your conversation with your provider. It does not select or predict a medication; your provider decides.
- An optional add-on — $298, or $99 for program members. Neither program includes a DNA-based test as part of its GLP-1 program.
- It does not recommend, prescribe, or determine which medication you should use, and it does not predict your response to any specific drug.
Which states is PlexusDx available in?
PlexusDx is available in most U.S. states where telehealth prescribing of these medications is permitted. You'll confirm whether your state is covered during intake. Fridays operates on a similar state-by-state basis.
Is shipping included?
Yes — PlexusDx includes direct-to-door shipping in its monthly price, with no separate shipping fee. Your medication ships from a state-licensed 503A pharmacy after your provider approves it. Fridays' captured checkout showed free shipping too.
What are the common side effects, and what support is there?
The most common GLP-1 side effects are gastrointestinal — nausea and digestive changes — usually most noticeable when starting or increasing a dose. Your provider titrates your dose to manage tolerability. This page is not medical advice.
- Every PlexusDx prescription includes a free 15-minute check-in with Dr. Jayden Lee, PharmD, for side-effect and medication questions.
- Discuss any symptoms with your provider.
PlexusDx tells you about your biology. It does not tell you what to put in your body.