Fridays vs PlexusDx: GLP-1 prices and programs compared
Month-to-month, PlexusDx charges $189 for semaglutide, below the $249 Fridays advertises on its own pricing page. Prepay a multi-month bundle, though, and Fridays' per-month equivalent drops under ours. The honest split is timing: PlexusDx wins on the monthly rate, while Fridays wins on prepaid bundles and includes unlimited provider visits, dietitian and coaching in every plan.
Is Fridays or PlexusDx better?
Month-to-month, PlexusDx costs less: $189/$289 versus the $249/$359 Fridays advertises. Prepaid, Fridays costs less: its 3- and 6-month bundles work out to per-month equivalents of $149/$142 and $224/$242.
This one is a genuine trade that splits on two questions: whether you pay month to month, where PlexusDx runs $60 to $70 under Fridays' advertised rates, or prepay a bundle, where Fridays' per-month equivalents drop below ours. It also splits on inclusions: Fridays bundles unlimited provider visits, dietitian support and mental-health coaching into every plan, while PlexusDx adds a free pharmacist check-in, an optional genetics layer, published rates and no lock-in on the monthly plan.
- You'll prepay a bundle for the lowest per-month cost. Its 3- and 6-month bundles work out to $149/$142 for semaglutide and $224/$242 for tirzepatide, each below our matching 3- and 6-month rates ($169/$149 and $269/$249). The bundles are charged upfront; the tirzepatide checkout we captured billed $896 as one payment recurring every four months, with a free fourth month.
- You want coaching built in. Every Fridays plan we captured bundles unlimited provider visits, 1-on-1 dietitian support, nutrition and mental-health coaching, and a care coach at no extra charge, a broader support package than PlexusDx includes.
- You want the lower month-to-month price. $189/$289 as one flat, all-inclusive charge covering the consult, prescription, medication and shipping, $60 and $70 below the $249/$359 Fridays advertises month-to-month on its own pricing page.
- You want pricing that stays put. PlexusDx's rates are published and the monthly plan has no lock-in; the Fridays bundle rates we captured moved between July 19 and July 20, and its campaign landing page priced differently from joinfridays.com.
- You want more formats. Semaglutide and tirzepatide injections, both orals, the GLP-Squared combination, and a $129 microdose, five in all, versus the two compounded programs in Fridays' captured flow. The orals cost more than the injections.
- You want a genetics option and pharmacist support. An optional genetics add-on ($298, or $99 for program members) and a free check-in with a Doctor of Pharmacy. The test doesn't select or predict a medication — your provider decides.
| Criterion | PlexusDx | Fridays |
|---|---|---|
| Month-to-month price ($189/$289 vs advertised $249/$359) | 5.0 | 3.0 |
| Prepaid multi-month price (its bundle per-month equivalents vs our 3-/6-month rates) | 3.5 | 4.5 |
| Price stability & transparency (published stable rates vs captured rates that moved within a day and differed by surface) | 5.0 | 2.5 |
| Bundled coaching (unlimited provider visits + dietitian + mental-health coaching vs our PharmD check-in) | 3.0 | 5.0 |
| Membership & extra fees ($0 at both — a tie) | 5.0 | 5.0 |
| Formats & options (five formats incl. oral & microdose vs the two captured compound programs) | 5.0 | 3.0 |
| Genetics & pharmacist support (optional DNA add-on + free PharmD check-in) | 4.5 | 3.0 |
Our own opinion scoring by the PlexusDx editorial team against each program's July 19–20, 2026 pricing and published offerings, not customer ratings. Fridays scores higher on prepaid bundle price and bundled coaching; membership is a tie at $0. We publish this comparison and are one of its two programs.
How much do Fridays and PlexusDx cost per month? (Verified July 2026)
PlexusDx is $189/month for semaglutide and $289 for tirzepatide month-to-month; Fridays advertises $249 and $359. On prepaid bundles Fridays is cheaper per month — $149/$142 and $224/$242 equivalents.
Month-to-month, the gap is $60 a month on semaglutide and $70 on tirzepatide against the rates Fridays advertises on its own pricing page. Prepay a bundle and Fridays goes below us — and we're not going to pretend otherwise. Two things to know about its ladder: the bundles are charged upfront (the captured tirzepatide checkout billed $896 as one payment recurring every four months), and it isn't strictly descending — tirzepatide's 3-month bundle works out cheaper per month than its 6-month, because only the 3-month carried the free-fourth-month promotion.
| Semaglutide — by term | PlexusDx | Fridays | Difference |
|---|---|---|---|
| Month-to-month | $189/mo, one all-inclusive charge | $249/mo — advertised, joinfridays.com/pricing, July 20, 2026 | PlexusDx −$60/mo |
| 3-month rate | $169/mo | $149/mo — per-month equivalent of a prepaid bundle (plan screen, July 19, 2026) | Fridays −$20/mo |
| 6-month rate | $149/mo | $142/mo — per-month equivalent of a prepaid bundle (plan screen, July 19, 2026) | Fridays −$7/mo |
| Checkout capture | Published rates — what you see is the rate | None reached for semaglutide in either session — the figures above are advertised and plan-screen figures only | — |
| Tirzepatide — by term | PlexusDx | Fridays | Difference |
|---|---|---|---|
| Month-to-month | $289/mo, one all-inclusive charge | $359/mo — advertised, joinfridays.com/pricing, July 20, 2026 | PlexusDx −$70/mo |
| 3-month rate | $269/mo | $224/mo — per-month equivalent of a prepaid bundle, verified against the captured checkout (July 20, 2026) | Fridays −$45/mo |
| 6-month rate | $249/mo | $242/mo — per-month equivalent of a prepaid bundle (plan screen, July 20, 2026) | Fridays −$7/mo |
| Its captured checkout (context) | — | $896 charged as one payment every 4 months (a ~$224/month equivalent that includes a free 4th month), captured via a promotional landing page, July 20, 2026 | Supporting figure — not a monthly price |
How Fridays' pricing works, as captured
- Advertised month-to-month: $249 semaglutide and $359 tirzepatide on joinfridays.com/pricing (live-checked July 20, 2026), which also lists $0 membership, signup and lab fees.
- Bundles are prepaid, on a four-month cycle: the captured tirzepatide checkout billed $896 as one payment, with the recurring line reading "$896 every 4 months" — three paid months plus a free fourth. That is the $224/month equivalent; it is not a monthly price.
- The free-fourth-month promotion came through a campaign landing page, applied automatically at checkout; it did not appear on joinfridays.com/pricing when we checked on July 20, 2026.
- The ladder isn't strictly descending: tirzepatide's 3-month bundle ($224/mo equivalent) works out cheaper per month than its 6-month ($242/mo), because only the 3-month carried the promotion.
- Shipping, refunds, cancellation: shipping was free at the captured checkout; Fridays commits to a full refund if its provider determines you're not eligible; its pricing page says you can cancel or pause anytime. Broader refund terms weren't captured.
- Semaglutide reached no checkout in either capture session — its figures on this page are advertised and plan-screen figures only.
Fridays figures: advertised rates live-checked on joinfridays.com/pricing, July 20, 2026; bundle per-month equivalents from its plan-selection screens, July 19–20, 2026; billed figure from one completed tirzepatide checkout reached through a promotional landing page, July 20, 2026.
PlexusDx figures: our own published all-inclusive rates, July 2026. Paired figures are semaglutide first, tirzepatide second. Prices change often — check both sites before deciding.
One flat monthly price — and it drops if you commit
Semaglutide $189/mo, tirzepatide $289/mo, all-inclusive — down to $149/$249 on a 6-month rate. A licensed provider reviews your intake before anything is prescribed.
How do PlexusDx and Fridays compare, feature by feature?
Both are cash-pay compounded-GLP-1 programs. Month-to-month, PlexusDx costs less; prepaid, Fridays costs less and bundles unlimited provider visits, dietitian and mental-health coaching.
| Feature | PlexusDx | Fridays |
|---|---|---|
| Month-to-month price | $189 / $289 | $249 / $359 — advertised, its pricing page, July 20, 2026 |
| Prepaid multi-month price (per-month equivalent) | $169–$149 / $269–$249 (3-/6-mo) | $149–$142 / $224–$242 (3-/6-mo bundles) |
| Billing structure | One flat, all-inclusive monthly charge | Prepaid bundle — one payment recurring every 4 months (captured tirz checkout) |
| Required membership fee | None ($0) | None ($0) — its own pricing page |
| Free shipping | Yes — included | Yes — free at the captured checkout |
| Price stability & lock-in | Published rates; no lock-in on the monthly plan | Captured rates moved within a day; campaign priced differently from its site |
| Oral (no-injection) option | Yes — oral sema & tirz (a premium format) | No — injectable sema & tirz in the flow we captured (July 2026) |
| Combination GLP-1 protocol | Yes — GLP-Squared | No |
| Lower-cost microdose entry | Yes — $129/mo | No |
| Optional genetics add-on | Yes — $298, or $99 for members | No |
| Bundled human support | Free PharmD check-in | Unlimited provider visits · 1-on-1 dietitian · mental-health coaching |
| Free named-pharmacist check-in | Yes — Dr. Jayden Lee, PharmD | No — bundles dietitian & coaching instead |
Compiled from Fridays' pricing page, plan screens and one captured tirzepatide checkout (July 19–20, 2026), alongside PlexusDx's published rates. Fridays' semaglutide reached no checkout — its figures are advertised only. Paired cells: semaglutide first, tirzepatide second.
When is Fridays the better choice?
Fridays is the better pick if you'll prepay a 3- or 6-month bundle for the lowest per-month cost, or want unlimited provider visits, dietitian and mental-health coaching bundled in.
- Its prepaid bundles cost less per month. Fridays' 3- and 6-month bundles work out to per-month equivalents of $149 and $142 for semaglutide, $224 and $242 for tirzepatide — each below PlexusDx's matching 3- and 6-month rates ($169/$149 and $269/$249). Each is the per-month equivalent of a prepaid bundle.
- The bundles are charged upfront. The tirzepatide checkout we captured billed $896 as one payment recurring every four months (July 20, 2026), with a free fourth month inside it.
- Coaching is built in. Every Fridays plan we captured bundles unlimited provider visits, 1-on-1 dietitian support, nutrition and mental-health coaching, and a care coach — a broader bundled support package than PlexusDx includes.
- $0 membership and free shipping: Fridays lists no membership, signup or lab fees on its own pricing page, and shipping was free at the captured checkout.
When is PlexusDx the better choice?
PlexusDx is the better pick if you want the lower month-to-month price, published rates that stay put with no prepay lock-in, more formats, or the genetics and pharmacist layer.
- The lower month-to-month price. $189 semaglutide and $289 tirzepatide as one flat, all-inclusive charge — $60 and $70 below the $249/$359 Fridays advertises month-to-month on its own pricing page.
- Pricing that stays put. PlexusDx's rates are published and the monthly plan has no lock-in; the Fridays bundle rates we captured moved between July 19 and July 20, and its campaign landing page priced differently from joinfridays.com.
- More formats. Semaglutide and tirzepatide injections, both orals, the GLP-Squared combination, and a $129 microdose — five in all, versus the injectable sema and tirz in Fridays' captured flow.
- Genetics and a pharmacist. An optional genetics add-on ($298, or $99 for program members) and a free check-in with a Doctor of Pharmacy. The test doesn't select or predict a medication — your provider decides.
What does PlexusDx offer that Fridays doesn't?
PlexusDx offers formats Fridays' injectable program doesn't: oral semaglutide and tirzepatide, a combination protocol, and a $129 microdose. Fridays offers injectable sema and tirz with rich bundled coaching.
- Both cover the two main compounds. PlexusDx and Fridays each offer semaglutide and tirzepatide; month-to-month, PlexusDx's $189/$289 undercut Fridays' advertised $249/$359.
- Fridays' strength is bundled human support — unlimited provider visits, 1-on-1 dietitian and mental-health coaching on every plan we captured. That is a genuine advantage PlexusDx doesn't match.
- PlexusDx's strength is format choice — a no-injection oral route, the GLP-Squared combination, and a lower-cost $129 microdose entry that didn't appear in Fridays' captured flow.
PlexusDx GLP-1 formats — published pricing, month-to-month first
- Semaglutide injection — $189/mo month-to-month · $169 (3-mo) · $149 (6-mo)
- Tirzepatide injection — $289/mo month-to-month · $269 (3-mo) · $249 (6-mo)
- Oral semaglutide — $289/mo month-to-month · $269 (3-mo) · $249 (6-mo) — a no-injection format
- Oral tirzepatide — $349/mo month-to-month · $299 (3-mo) · $279 (6-mo)
- GLP-Squared combination protocol — $289/mo month-to-month · $249 (3-mo)
- Microdose GLP-1 — $129/mo flat, a lower-cost entry point
Fridays' captured flow (July 2026) offered injectable compounded semaglutide and tirzepatide, each advertised at $249/$359 month-to-month and bundling unlimited provider visits, 1-on-1 dietitian and mental-health coaching. PlexusDx formats show published month-to-month rates first.
How does Fridays' pricing work?
Fridays advertises $249 semaglutide and $359 tirzepatide month-to-month on its pricing page. Its lower per-month rates come from prepaid 3- and 6-month bundles charged upfront.
Two things shape every Fridays figure on this page, and both are why each one carries a date and a surface.
- The bundles are prepaid, on a four-month cycle. The captured tirzepatide checkout billed $896 as one payment, with the recurring line reading "$896 every 4 months" — three paid months plus a free fourth. That is the $224/month equivalent; it is not a monthly price.
- The free fourth month came through a campaign landing page, applied automatically at checkout; it did not appear on joinfridays.com/pricing when we checked on July 20, 2026.
- The ladder isn't strictly descending. Tirzepatide's 3-month bundle ($224/mo equivalent) works out cheaper per month than its 6-month ($242/mo), because only the 3-month carried the promotion.
- The rates moved fast. The Fridays bundle rates we captured moved materially between July 19 and July 20, and its campaign landing page priced differently from joinfridays.com — so every Fridays figure here names its date and its surface.
- $0 membership, free shipping, eligibility refund. Fridays lists no membership, signup or lab fees; shipping was free at checkout; it commits to a full refund if its provider determines you're not eligible, and its pricing page says you can cancel or pause anytime. Broader refund terms weren't captured.
- The "$425 value" is a claimed value of a bundled inclusion, not a fee. Fridays frames its included coaching as $425 of care; nobody is charged $425.
How does PlexusDx pricing work?
PlexusDx charges one flat, all-inclusive price per medication, the same at every dose — semaglutide $189/mo and tirzepatide $289/mo month-to-month, dropping to $149/$249 on a 6-month plan.
Where the two part ways is the month-to-month price and the durability of it: PlexusDx's $189/$289 sit $60–$70 below Fridays' advertised rates and don't move by campaign or by day. Fridays wins back the gap only if you prepay a bundle — which is a single upfront charge on a four-month cycle, not a monthly rate.
Fridays figures: advertised rates from joinfridays.com/pricing (July 20, 2026); bundle per-month equivalents from its plan screens (July 19–20, 2026); billed cadence from one tirzepatide checkout via a promotional landing page (July 20, 2026). PlexusDx: published all-inclusive rates, July 2026.
Does either program look at your biology or include pharmacist support?
Neither program includes a DNA-based test as part of its GLP-1 program. PlexusDx offers one as an optional add-on — $298, or $99 for program members.
First, credit where it's due: Fridays bundles unlimited provider visits, 1-on-1 dietitian support, and nutrition and mental-health coaching into every plan we captured — a broader human-support package than PlexusDx includes.
What PlexusDx adds is a layer neither program bundles — an optional look at your biology, and a pharmacist to talk it through.
- What it is: the optional Precision Peptide Genetic Test gives you and your licensed provider added clarity on how your body is wired — context to bring to your care, not a substitute for it.
- Price: $298, or $99 for program members — members receive a discount code about 10 days after their order.
- What it isn't: it does not select or predict a medication; your provider decides. It's context, not a prescription.
Every PlexusDx prescription includes a free 15-minute check-in with our Medical Director and Doctor of Pharmacy — by video or phone — for medication questions, side effects, and how your protocol is going. It's education and support; your licensed provider still makes every prescribing decision.
How did we verify these prices?
We took Fridays' month-to-month rates from its own pricing page on July 20, 2026, and captured one tirzepatide checkout — the $896 four-month bundle — through a promotional landing page.
Method. Fridays' month-to-month rates come from joinfridays.com/pricing, live-checked July 20, 2026. Its lower per-month figures come from the plan-selection screens, and one tirzepatide checkout — reached through a promotional paid-search landing page on July 20 — billed $896 as a single payment recurring every four months. Those captures are the source for every Fridays figure here; we used no third-party review site.
Why every figure carries a date and a surface. Fridays' captured pricing did not hold still. The bundle rates we recorded moved materially within about 13.5 hours — between the evening of July 19 and the morning of July 20 — and its campaign landing page priced differently from joinfridays.com. Semaglutide reached no checkout at all, so its figures are advertised-only. Every Fridays number here is stamped with the date and the exact surface it came from.
A note on who wrote this. PlexusDx publishes this page and is one of the two programs compared, so we are not a neutral party. That's why we used Fridays' own pricing page and captured checkout as the only source for its figures, and why we state plainly where Fridays beats us — on prepaid bundle prices and on bundled coaching. Category pricing changes often; check both sites before you decide.
- Fridays' prepaid bundles cost less per month. Its 3- and 6-month bundles work out to per-month equivalents of $149/$142 (semaglutide) and $224/$242 (tirzepatide) — below PlexusDx's matching 3- and 6-month rates, though charged upfront on a four-month cycle.
- Fridays bundles richer human coaching. Every plan we captured includes unlimited provider visits, 1-on-1 dietitian support, and nutrition and mental-health coaching — a broader support package than PlexusDx includes.
See your PlexusDx price — one flat, all-inclusive charge
One published price covering the provider consult, prescription, medication and shipping — semaglutide $189/mo, tirzepatide $289/mo month-to-month, down to $149/$249 on a 6-month rate. A licensed provider reviews your intake before anything is prescribed.
Start your intakeFrequently Asked Questions
What is compounded GLP-1?
Compounded GLP-1 medications are semaglutide or tirzepatide prepared for an individual patient by a state-licensed 503A compounding pharmacy on a valid prescription. They are not FDA-approved. Both Fridays and PlexusDx operate in this category.
- Not FDA-reviewed. Compounded medications are not reviewed by the FDA for safety, quality, or effectiveness.
- The approved versions. Only Novo Nordisk (semaglutide) and Lilly (tirzepatide) make FDA-approved branded products.
Are compounded GLP-1 medications FDA-approved?
No — compounded medications are not FDA-approved and are not reviewed by the FDA for safety, quality, or effectiveness. They are prepared by a state-licensed 503A pharmacy for an individual patient on a valid prescription.
- Semaglutide. Novo Nordisk is the only U.S. company with FDA-approved semaglutide (Wegovy®, Ozempic®, Rybelsus®).
- Tirzepatide. Lilly is the only U.S. company with FDA-approved tirzepatide (Zepbound®, Mounjaro®).
Is PlexusDx cheaper than Fridays?
It depends on how you pay: month-to-month PlexusDx is cheaper — $189/$289 versus the $249/$359 Fridays advertises — but Fridays' prepaid bundles cost less per month. On its 3- and 6-month bundles Fridays works out lower.
- Month-to-month, PlexusDx wins by $60–$70/month — $189 vs $249 (semaglutide) and $289 vs $359 (tirzepatide), the rates Fridays advertised on its pricing page on July 20, 2026.
- Prepaid, Fridays wins. Its 3- and 6-month bundles work out to $149/$142 (semaglutide) and $224/$242 (tirzepatide) per month — below our matching rates — but are charged upfront on a four-month cycle.
- Its bundle rates moved within a day and its campaign landing page priced differently from its site, so check both before deciding.
How much does Fridays cost per month?
Fridays advertises $249/month for semaglutide and $359 for tirzepatide month-to-month on its own pricing page, checked July 2026. Its prepaid bundles cost less per month but are charged upfront on a four-month cycle.
- Prepaid per-month equivalents: $149/$142 (semaglutide) and $224/$242 (tirzepatide) on its 3- and 6-month bundles (plan screens, July 19–20, 2026) — each the per-month equivalent of a bundle, not a monthly price.
- The tirzepatide checkout we captured billed $896 as one payment recurring every four months — three paid plus a free fourth — reached through a promotional landing page on July 20, 2026.
- Semaglutide reached no checkout, so its figures are advertised only.
Does Fridays charge a membership fee?
No — Fridays charges no membership fee; its own pricing page lists $0 membership, signup and lab fees. Shipping was free at the checkout we captured, too.
- We verified $0 three ways — its pricing page, its own comparison table, and the absence of any membership line on the captured checkout.
- Neither program charges a membership. PlexusDx also has no membership fee; its price is one flat, all-inclusive charge.
How do Fridays' prepaid bundles work?
Fridays' 3- and 6-month bundles are prepaid — charged upfront as one payment on a recurring four-month cycle, not billed monthly. The tirzepatide bundle we captured billed $896 every four months.
- The ladder isn't strictly descending. Tirzepatide's 3-month bundle ($224/mo equivalent) works out cheaper per month than its 6-month ($242/mo), because only the 3-month carried a free-fourth-month promotion.
- The promotion came through a campaign landing page, applied automatically at checkout; it didn't appear on joinfridays.com/pricing when we checked on July 20, 2026.
- PlexusDx's 3- and 6-month rates are per-month prices with no upfront bundle — $169/$149 (semaglutide) and $269/$249 (tirzepatide).
How much does PlexusDx cost per month?
Month-to-month, PlexusDx is $189 for semaglutide and $289 for tirzepatide — one flat, all-inclusive charge covering the consult, prescription, medication and shipping. Rates drop to $149/$249 on a 6-month plan.
- The same at every dose — no dose surcharge, and no separate membership.
- Other formats: oral semaglutide ($289) and tirzepatide ($349), the GLP-Squared combination ($289), and a $129 microdose entry.
Can I cancel anytime, or am I locked into a contract?
PlexusDx's month-to-month plan has no contract — you can stop between refills — and Fridays' pricing page says you can cancel or pause anytime.
- PlexusDx's 3- and 6-month rates involve a longer commitment for a lower price; its longest plan is 6 months.
- Fridays' bundles are prepaid on a four-month cycle, so the upfront period is what you commit to; broader refund terms weren't captured.
Which program includes more coaching and support?
Fridays includes more bundled coaching — every plan we captured came with unlimited provider visits, 1-on-1 dietitian support, and mental-health coaching. PlexusDx includes a free pharmacist check-in instead.
- Fridays' bundled support is a genuine advantage PlexusDx doesn't match on the coaching side.
- PlexusDx adds a different layer — a free 15-minute check-in with Dr. Jayden Lee, PharmD, and an optional genetics add-on your provider can factor in.
What does the PlexusDx genetics test do?
It analyzes how your genes influence weight-management-related biological pathways, to inform your conversation with your provider. It does not select or predict a medication; your provider decides.
- An optional add-on — $298, or $99 for program members. Neither program includes a DNA-based test as part of its GLP-1 program.
- It does not recommend, prescribe, or determine which medication you should use, and it does not predict your response to any specific drug.
Which states is PlexusDx available in?
PlexusDx is available in most U.S. states where telehealth prescribing of these medications is permitted. You'll confirm whether your state is covered during intake. Fridays operates on a similar state-by-state basis.
Is shipping included?
Yes — PlexusDx includes direct-to-door shipping in its monthly price, with no separate shipping fee. Your medication ships from a state-licensed 503A pharmacy after your provider approves it. Fridays' captured checkout showed free shipping too.
What are the common side effects, and what support is there?
The most common GLP-1 side effects are gastrointestinal — nausea and digestive changes — usually most noticeable when starting or increasing a dose. Your provider titrates your dose to manage tolerability. This page is not medical advice.
- Every PlexusDx prescription includes a free 15-minute check-in with Dr. Jayden Lee, PharmD, for side-effect and medication questions.
- Discuss any symptoms with your provider.
PlexusDx tells you about your biology. It does not tell you what to put in your body.