Last reviewed: September 1, 2026
Last updated: September 1, 2026
Written by: Jay Hastings, CEO of PlexusDx
Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.
Medically reviewed by: Jayden Lee, PharmD, EMBA
Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.
PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.
The short answer
Peak Wellness delivers the simpler month-to-month value for injectable semaglutide ($249) and tirzepatide ($349), undercutting Henry Meds' $297 semaglutide rate by $48. PlexusDx undercuts both: $189 for semaglutide, $289 for tirzepatide, both month-to-month with no commitment. Henry's advantage lies in its 12-month prepaid floor ($197/month equivalent for semaglutide, $2,364 paid in full) and broader oral format menu—oral semaglutide at $249 plus oral tirzepatide and microdose options with published pricing. Peak offers no 12-month plan and no oral formats. All three include provider access, supplies, and shipping in one flat charge; none charges a membership fee. If flexibility and the lowest ongoing rate matter most, PlexusDx wins. If you value a 12-month lock-in for cost certainty and oral alternatives interest you, Henry has the edge. Peak sits between: clearer than Henry's multi-tier pricing, cheaper than Henry's base rate, but more expensive than PlexusDx across every plan length.
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At-a-glance comparison
| Feature |
Henry Meds |
Peak Wellness |
PlexusDx |
| Semaglutide injection MTM |
$297/mo |
$249/mo |
$189/mo |
| Tirzepatide injection MTM |
Not offered* |
$349/mo |
$289/mo |
| 6-month semaglutide prepaid |
$1,482 total ($247/mo equiv.) |
$990 total ($165/mo equiv.) |
$894 total ($149/mo equiv.) |
| 6-month tirzepatide prepaid |
— |
$1,396 total ($233/mo equiv.) |
$1,494 total ($249/mo equiv.) |
| 12-month plan |
$2,364 semaglutide ($197/mo equiv.) |
Not offered |
Not offered |
| Oral formats |
Sema $249; tirz offered (no monthly rate) |
None |
Sema $289; tirz $349 |
| Microdose GLP-1 |
Offered (rate not captured) |
Not offered |
$129/mo |
| Membership fee |
None |
None |
None |
| Cancellation (MTM) |
Anytime; prepaid may require paying out balance |
Anytime, no fee; takes effect next billing cycle |
Anytime |
| Compounding partner type |
Both types mentioned |
503A pharmacies (four named) |
503A pharmacies |
*Henry offers tirzepatide as an oral dissolving tablet; no monthly injectable tirzepatide rate was captured. Prices verified at checkout September 1, 2026.
Normalized pricing: like-for-like plans and 12-month cost
Month-to-month rates are the clearest comparison point because they carry no commitment penalty. For injectable semaglutide, PlexusDx charges $189, Peak $249, and Henry $297—a $60 monthly spread between the cheapest and most expensive. Over 12 months with no commitment, that gap compounds: PlexusDx $2,268, Peak $2,988, Henry $3,564. PlexusDx saves $720 against Peak and $1,296 against Henry across a year of month-to-month billing.
For injectable tirzepatide, only Peak and PlexusDx publish month-to-month rates (Henry's tirzepatide is oral only). Peak charges $349; PlexusDx $289. Over 12 months: Peak $4,188, PlexusDx $3,468, a $720 annual difference favoring PlexusDx.
Prepaid plans
All three providers offer 6-month prepaid plans for injectable semaglutide. Henry charges $1,482 upfront ($247/month equivalent, our calculation); Peak $990 ($165/month equivalent); PlexusDx $894 ($149/month equivalent). Paying for two consecutive 6-month cycles yields a 12-month total: Henry $2,964, Peak $1,980, PlexusDx $1,788. PlexusDx saves $192 against Peak and $1,176 against Henry over a full year on a 6-month-commitment rhythm.
For tirzepatide, Peak's 6-month prepaid total is $1,396 ($233/month equivalent); PlexusDx $1,494 ($249/month equivalent). Peak wins the 6-month tirzepatide comparison by $98, and over two cycles (12 months) Peak costs $2,792 versus PlexusDx $2,988—a $196 annual advantage for Peak. This is the only term length and compound where Peak delivers a lower 12-month cost than PlexusDx.
Henry's 12-month prepaid semaglutide plan charges $2,364 upfront ($197/month equivalent, our calculation). That total undercuts Henry's own two-6-month-cycle cost ($2,964) by $600, and it beats Peak's 12-month equivalent ($1,980 via two 6-month cycles) by $384. However, PlexusDx's 12-month cost via two 6-month cycles ($1,788) still saves $576 against Henry's 12-month plan. Henry's 12-month plan is the longest single commitment among the three and delivers cost certainty for a full year, but it does not deliver the lowest 12-month total.
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Decision factors: strengths and gaps
Henry Meds strengths
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Longest prepaid option: The 12-month semaglutide plan ($2,364) locks in a rate for a full year and eliminates billing friction. No other provider in this comparison offers a plan longer than 6 months.
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Oral format breadth: Oral semaglutide at $249/month and oral tirzepatide (format confirmed, monthly rate not captured) give needle-averse patients alternatives. PlexusDx also offers oral formats, but Henry's oral semaglutide rate is $40 cheaper than PlexusDx's $289.
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Microdose availability: Henry lists microdose GLP-1 in its menu, though no monthly rate was captured in the September 2026 evidence. This may appeal to maintenance patients.
Henry Meds gaps
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Highest month-to-month rate: $297 for injectable semaglutide is $48 more than Peak and $108 more than PlexusDx every month.
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No injectable tirzepatide: Henry's tirzepatide is oral only. Patients who prefer or require injectable tirzepatide must look elsewhere.
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Multi-month exit cost: Prepaid plans may require paying out the remaining balance unless a healthcare provider determines you are medically unable to continue. This reduces the flexibility of lower committed-term rates.
Peak Wellness strengths
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Wins 6-month tirzepatide: $1,396 for six months ($233/month equivalent) beats PlexusDx's $1,494 by $98. Over 12 months (two cycles), Peak saves $196.
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Simple tier structure: Three plan lengths (month-to-month, 3-month, 6-month) with clear upfront totals. No 12-month commitment removes the risk of a long lock-in.
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Pre-authorization with charge-on-approval: You authorize payment at checkout but are only charged if a physician prescribes. This reduces upfront financial risk.
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Named pharmacy partners: Peak lists four 503A compounding pharmacies by name and location (Emerald Compounding, Epiq Scripts, Southend Pharmacy, AbsoluteRX), adding supply-chain transparency.
Peak Wellness gaps
-
No oral formats: Injectable only. Needle-averse patients have no alternative route.
-
Month-to-month rates lag PlexusDx: $249 semaglutide and $349 tirzepatide are $60 more per compound per month than PlexusDx. Over a year, that costs $720 extra per compound.
-
Prepaid refund policy unclear: Peak's terms state you can cancel anytime with no fee, and changes take effect at the next billing cycle, but how unused months are treated on a prepaid 3- or 6-month package was not documented in the September 2026 capture.
PlexusDx strengths
-
Lowest month-to-month rates: $189 semaglutide and $289 tirzepatide, both injectable, with no commitment. This delivers maximum flexibility and the smallest recurring cost.
-
Lowest 12-month semaglutide cost via 6-month cycles: $1,788 (two 6-month cycles at $894 each) beats both Peak ($1,980) and Henry ($2,364 on a 12-month plan, $2,964 on two 6-month cycles).
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Format variety: Five protocols including injectable and oral semaglutide, injectable and oral tirzepatide, and microdose GLP-1 at $129/month. All with published monthly rates.
-
Optional genetics add-on: $298 standalone, $99 for program members. The test does not select or predict medication—provider decision remains independent—but some patients value data on how genes may influence medication response for broader medication management.
-
Free PharmD check-in: Access to a Doctor of Pharmacy without additional charge, offering a second layer of medication expertise beyond the prescribing provider.
PlexusDx gaps
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No 12-month single-commitment plan: Longest prepaid option is 6 months. Patients who want to lock in a full year in one transaction must either choose two 6-month cycles or select Henry's 12-month plan.
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Loses 6-month tirzepatide to Peak: PlexusDx charges $1,494 for six months; Peak $1,396. Peak saves $98 on that specific term.
Choose Henry Meds if…
- You want to prepay a full year in one transaction and eliminate monthly billing friction. Henry's 12-month semaglutide plan ($2,364) is the only single-commitment 12-month option in this comparison.
- Oral semaglutide at $249/month interests you and you value a slightly lower rate than PlexusDx's $289 oral option.
- You are willing to pay a higher month-to-month rate ($297 semaglutide) in exchange for a broader oral menu and potential microdose access.
- You prefer a provider that mentions partnerships with both compounding pharmacy types in its documentation.
Choose Peak Wellness if…
- You want injectable tirzepatide on a 6-month prepaid plan and $1,396 ($233/month equivalent) fits your budget better than PlexusDx's $1,494.
- You value charge-on-approval billing (pre-authorized at checkout, charged only if prescribed) and want to avoid any upfront payment before a physician reviews your case.
- Transparent pharmacy sourcing matters: Peak names its four 503A partners with city and state locations.
- You want a middle-ground month-to-month rate—lower than Henry, higher than PlexusDx—with no membership fee and straightforward cancellation.
Choose PlexusDx if…
- You want the lowest month-to-month injectable rates with zero commitment: $189 semaglutide, $289 tirzepatide. That flexibility saves $720/year per compound against Peak and more against Henry.
- You want the lowest 12-month semaglutide cost via two 6-month cycles ($1,788 total) without locking into a single 12-month contract.
- Format variety matters: you want published pricing for injectable and oral semaglutide, injectable and oral tirzepatide, and microdose GLP-1 ($129/month) all in one place.
- You value optional genetic testing ($99 for members) and free PharmD consultations alongside your prescribing provider.
- You prefer the certainty of 503A-only compounding partnerships.
Methodology and freshness
All prices, plan terms, and inclusion details were captured from provider checkout flows, pricing pages, and terms-of-service documents on September 1, 2026. Henry Meds rates verified at henrymeds.com checkout and FAQs; Peak Wellness rates verified at trypeak.com pricing and terms pages; PlexusDx rates verified at plexusdx.com product pages. Per-month equivalents for prepaid plans (for example, $165/month for Peak's $990 six-month semaglutide total) are our calculation and labeled as such throughout this article. We publish only standard ongoing month-to-month rates and prepaid package totals. Where the evidence shows Peak's $990 semaglutide six-month total as either an upfront charge or expressed as a per-month equivalent in different sources, we state both the verified upfront total and the calculated monthly figure with transparent attribution. No rate older than the stated capture date appears in any comparison table or cost calculation. Readers should confirm current rates, term lengths, and cancellation policies at each provider's checkout before committing.
Frequently Asked Questions
Does Henry Meds offer injectable tirzepatide?
No. Henry Meds offers tirzepatide as an oral dissolving tablet only. No monthly rate for injectable tirzepatide was captured in the September 2026 evidence. If you require injectable tirzepatide, Peak Wellness and PlexusDx both publish month-to-month and prepaid rates for that format.
Which provider has the cheapest month-to-month semaglutide injection?
PlexusDx at $189/month, verified September 1, 2026. Peak Wellness charges $249; Henry Meds $297. PlexusDx saves $60/month against Peak and $108/month against Henry, with no membership fee and no commitment required on the month-to-month plan.
Can I get a refund if I prepay six months and want to stop early?
Henry Meds states that multi-month plans may require paying out the remaining balance unless a healthcare provider determines you are medically unable to continue. Peak Wellness allows cancellation anytime with no fee, changes effective at the next billing cycle, but how unused prepaid months are treated was not detailed in captured terms. PlexusDx offers month-to-month and prepaid plans; cancellation terms for prepaid balances should be confirmed at checkout.
Which provider offers oral GLP-1 options?
Henry Meds offers oral semaglutide at $249/month and lists oral tirzepatide (no monthly rate captured). PlexusDx offers oral semaglutide at $289/month and oral tirzepatide at $349/month. Peak Wellness offers injectable formats only; no oral options were documented in the September 2026 capture.
Does any provider charge for membership or separate consultation fees?
No. Henry Meds, Peak Wellness, and PlexusDx all include provider consultations, medication, supplies, and shipping in one monthly charge with no separate membership fee. Henry and Peak charge only if a provider prescribes medication after your evaluation; PlexusDx follows the same model.
Sources
- Henry Meds pricing and plan details, henrymeds.com checkout and product pages, accessed September 1, 2026
- Henry Meds inclusions and service overview, henrymeds.com about and FAQ pages, accessed September 1, 2026
- Henry Meds cancellation and shipping terms, henrymeds.com FAQ, accessed September 1, 2026
- Peak Wellness pricing and plan structure, trypeak.com pricing page, accessed September 1, 2026
- Peak Wellness terms of service, pharmacy partners, and support details, trypeak.com terms and FAQ, accessed September 1, 2026
- PlexusDx weight-management protocol pricing and inclusions, plexusdx.com product pages, accessed September 1, 2026
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Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.
Medical and Editorial Standards
Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.
Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.
Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.
Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.
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