Last reviewed: September 1, 2026 Last updated: September 1, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

Eden charges $198 per month for semaglutide and $298 per month for tirzepatide, split into separate medication and membership charges. Fridays advertises $249 per month for semaglutide and $359 per month for tirzepatide as all-in rates on its pricing page, though PlexusDx has not completed Fridays' checkout to verify the recurring charge—readers should confirm at checkout. PlexusDx charges $189 per month for semaglutide and $289 per month for tirzepatide with no membership fee, and offers lower committed-term rates when paid in 3- or 6-month increments. Eden offers a 10% weight-loss-in-6-months money-back pledge; Fridays bundles unlimited provider visits, dietitian support, and coaching at no extra charge; PlexusDx offers five medication formats including oral capsules and a microdose maintenance option. The lowest monthly price among verified providers is PlexusDx at $189 for semaglutide, $108 per year less than Eden and $720 per year less than Fridays' advertised rate; for tirzepatide, PlexusDx is $289, $108 less than Eden and $840 less than Fridays' advertised rate annually.

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At-a-glance comparison

Feature Eden Fridays PlexusDx
Semaglutide MTM $198/month
verified 2026-07-19
$249/month
advertised 2026-07-20
$189/month
verified 2026-09-01
Tirzepatide MTM $298/month
verified 2026-07-19
$359/month
advertised 2026-07-20
$289/month
verified 2026-09-01
Membership fee $99/month required $0 $0
Billing structure Two recurring charges (medication + membership) Single all-in charge Single all-in charge
Multi-month rates Not offered Annual option mentioned, no published rate 3-mo: $169/$269
6-mo: $149/$249
prepaid, per-month equivalent
Formats Injection only Injection only Injection, oral, microdose
Money-back pledge 10% weight loss in 6 months or refund Not mentioned Not offered
Bundled support Not detailed Unlimited provider visits, dietitian, mental-health coaching, care coach Free PharmD check-in
Cancellation Cancel anytime Not stated in captured sources Cancel anytime (MTM)

Verification note: Fridays' $249/$359 figures are advertised on its own pricing page as of July 20, 2026. PlexusDx has not completed Fridays' checkout to verify the recurring charge. Readers should confirm final pricing at checkout.

Like-for-like monthly pricing

Eden bills two charges each month: $99 for medication and $99 for membership. The all-in cost is $198 per month for compounded semaglutide and $298 per month for compounded tirzepatide. Both plans are monthly-only; Eden does not publish multi-month rates. The checkout states "Cancel anytime" and "Card won't be charged until plan is medically approved within 24 hours." The membership is required, not optional. Verified July 19, 2026.

Fridays advertises $249 per month for compounded semaglutide and $359 per month for compounded tirzepatide on its pricing page. The advertised rate is all-in, with $0 membership fee, $0 signup fee, and $0 lab fees. An annual option is mentioned on the site but no standing multi-month per-month rate is published. PlexusDx observed that Fridays' campaign landing page priced differently from its main site when captured July 20, 2026, so readers should verify the checkout price. Advertised July 20, 2026.

PlexusDx charges $189/mo month-to-month for compounded semaglutide injection and $289/mo month-to-month for compounded tirzepatide injection, with no membership fee. The charge is all-inclusive: provider visit, prescription, medication, and shipping. Month-to-month plans can be canceled anytime. Verified September 1, 2026.

12-month cost comparison (month-to-month plans)

The following annual totals assume continuous month-to-month billing with no plan changes. All figures are our calculation.

Semaglutide:

  • PlexusDx: $189/month × 12 = $2,268 per year
  • Eden: $198/month × 12 = $2,376 per year
  • Fridays (advertised): $249/month × 12 = $2,988 per year

Tirzepatide:

  • PlexusDx: $289/month × 12 = $3,468 per year
  • Eden: $298/month × 12 = $3,576 per year
  • Fridays (advertised): $359/month × 12 = $4,308 per year

PlexusDx month-to-month plans cost $108 per year less than Eden for both semaglutide and tirzepatide. Compared to Fridays' advertised rates, PlexusDx saves $720 per year on semaglutide and $840 per year on tirzepatide. Eden's month-to-month plans cost $612 per year less than Fridays' advertised semaglutide rate and $732 per year less for tirzepatide.

Multi-month prepaid rates

PlexusDx offers lower per-month rates when paid in 3- or 6-month increments. The 3-month rate for semaglutide is $169 per month (prepaid, our calculation: $169 × 12 = $2,028 per year); the 6-month rate is $149 per month (prepaid, our calculation: $149 × 12 = $1,788 per year). For tirzepatide, the 3-month rate is $269 per month (our calculation: $269 × 12 = $3,228 per year); the 6-month rate is $249 per month (our calculation: $249 × 12 = $2,988 per year). These rates require upfront payment for the full term. Verified September 1, 2026.

Eden does not offer multi-month rates; all plans are monthly-only. Fridays mentions an annual option on its site but does not publish a standing multi-month per-month rate, so no multi-month comparison is possible.

PlexusDx semaglutide: $189/month—$108/year less than Eden, $720/year less than Fridays' advertised rate

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Decision factors beyond price

Eden's money-back pledge and split billing

Eden offers a "Lose 10% in 6 months or get your money back" pledge on compounded plans. The captured sources do not detail full eligibility conditions or exclusions; readers considering Eden for this feature should request the complete terms. The two-charge billing structure—$99 medication, $99 membership—means your bank statement will show separate recurring transactions. The membership is required, not optional, so the all-in cost is always $198 for semaglutide or $298 for tirzepatide. Plans are monthly-only; there is no way to lock in a lower rate for a longer term. Verified July 19, 2026.

Fridays' bundled support and zero-fee structure

Fridays advertises unlimited provider visits, 1-on-1 dietitian support, nutrition coaching, mental-health coaching, and a care coach—all included at no extra charge. Lab fees are $0; membership and signup fees are $0; shipping is free. Required labs typically include a comprehensive metabolic panel, hemoglobin A1C, TSH, and lipid panel. This support bundle may offer meaningful value to readers who want frequent clinician contact, structured meal planning, or behavioral coaching. Because PlexusDx has not completed Fridays' checkout, cancellation terms and the exact recurring charge are not verified—confirm both at checkout. Advertised July 20, 2026.

PlexusDx's format variety and committed-term savings

PlexusDx offers five medication formats: semaglutide injection, tirzepatide injection, semaglutide oral capsules, tirzepatide oral capsules, and a microdose GLP-1 maintenance protocol. Oral capsules may suit readers who prefer to avoid injections; the microdose protocol is designed for weight maintenance after initial loss. Month-to-month plans carry no membership fee and can be canceled anytime. Readers willing to commit 3 or 6 months can access lower per-month rates: $169/$269 for 3 months, $149/$249 for 6 months, paid in full at the start of the term. Every plan includes a free PharmD check-in. An optional DNA-based medication-response add-on is available for $298 standalone or $99 for program members. Verified September 1, 2026.

Choose Eden if…

You want a structured accountability mechanism and are willing to pay $198–$298 per month for a money-back pledge tied to 10% weight loss in six months. You are comfortable with two recurring charges on your payment method and do not need access to multi-month pricing or non-injection formats. Confirm the full terms of the money-back guarantee before enrollment.

Choose Fridays if…

You value comprehensive support—unlimited provider visits, dietitian consultations, nutrition and mental-health coaching—and are willing to pay Fridays' advertised $249–$359 per month for that bundle. You want $0 lab fees and prefer a single all-in charge with no separate membership. Because PlexusDx has not verified Fridays' checkout, confirm the final recurring price, cancellation terms, and support-bundle details at enrollment.

Choose PlexusDx if…

You want the lowest verified month-to-month price—$189 for semaglutide, $289 for tirzepatide—with no membership fee and a single all-inclusive charge. You prefer access to five medication formats, including oral capsules and a microdose maintenance option. You are willing to commit 3 or 6 months upfront to access lower per-month rates ($169/$269 or $149/$249), or you want the flexibility to cancel anytime on the month-to-month plan. You value transparent per-month pricing with no split billing.

Methodology and freshness

Eden pricing, billing structure, cancellation terms, money-back pledge, and medication formats were captured from Eden's checkout flow and verified July 19, 2026. Fridays' $249/$359 advertised rates, bundled support inclusions, and zero-fee structure were captured from Fridays' own pricing page on July 20, 2026; PlexusDx has not completed Fridays' checkout to verify the recurring charge, so readers should confirm final pricing and cancellation terms at enrollment. PlexusDx pricing, fees, format availability, and cancellation terms were verified September 1, 2026. All 12-month cost totals and per-month savings figures are our calculation, derived by multiplying the stated monthly rate by twelve. Multi-month per-month equivalents for PlexusDx are our calculation based on prepaid rates. We present standard ongoing rates and prepaid totals only; no temporary, conditional, or figures appear in this comparison.

Frequently Asked Questions

Why does Eden charge two separate fees?

Eden bills $99 for medication and $99 for membership as two recurring charges each month. The membership is required, not optional, so the all-in cost is always $198 for semaglutide or $298 for tirzepatide. Your bank statement will show both transactions separately.

Are Fridays' advertised rates verified at checkout?

No. PlexusDx captured Fridays' $249/$359 rates from its pricing page on July 20, 2026, but has not completed Fridays' checkout. We also observed that Fridays' campaign landing page priced differently from its main site when captured. Confirm the final recurring charge and all terms at enrollment.

Does PlexusDx require a membership fee?

No. PlexusDx charges a single all-inclusive monthly rate with no separate membership, signup, or recurring subscription fee. The $189/$289 month-to-month price covers your provider visit, prescription, medication, and shipping.

Can I switch from semaglutide to tirzepatide mid-program?

Policies vary by provider. PlexusDx allows medication changes with provider approval; confirm Eden's and Fridays' switch policies and any associated fees before enrollment, as the captured sources do not detail mid-program changes.

What is included in Fridays' support bundle?

Fridays advertises unlimited provider visits, 1-on-1 dietitian support, nutrition coaching, mental-health coaching, and a care coach—all included at no extra charge. Lab fees, membership fees, and shipping are also $0. Confirm the scope and access frequency of each service at checkout.

Sources

  • Eden pricing, billing structure, cancellation terms, money-back pledge, and medication formats: Eden checkout flow, accessed July 19, 2026.
  • Fridays advertised pricing, bundled support, zero-fee structure, and required labs: Fridays pricing page (joinfridays.com/pricing), accessed July 20, 2026.
  • PlexusDx pricing, fees, format availability, cancellation terms, and PharmD check-in: PlexusDx product pages and checkout flow, accessed September 1, 2026.
  • Fridays verification status and price-stability observation: PlexusDx internal comparison table, accessed September 1, 2026.

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Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.