Last reviewed: September 14, 2026 Last updated: September 14, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

Fourteen providers offer month-to-month compounded GLP-1 medication without annual lock-in. The lowest all-in recurring costs for compounded semaglutide injection are PlexusDx at $189/month and Eden at $198/month (medication plus membership). For compounded tirzepatide injection, PlexusDx at $289/month and Eden at $298/month lead. Several providers advertise introductory or promotional rates that reset to higher refill prices, and at least six charge separate membership fees. Where the evidence was sufficient to verify checkout prices, we calculated 12-month total costs to reveal the true recurring commitment.

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At-a-glance: month-to-month compounded GLP-1 pricing

Provider Semaglutide Injection MTM Tirzepatide Injection MTM Membership Fee Source Capture
PlexusDx $189/month $289/month None Jul 2026
Eden $99 med + $99 membership = $198/month $199 med + $99 membership = $298/month $99/month (first month $39 promo) Sep 2026
Peak Wellness $249/month $349/month None stated Jul 2026
Fridays Health $249/month (advertised) $359/month (advertised) None stated Sep 2026
Found (cash MTM) $289/month $359/month Included Sep 2026
Henry Meds $297/month injection Not offered as injection; oral 3-month $297/month prepaid None Sep 2026
TrimRx $299/month (verified ongoing; advertised $199) $399/month (verified ongoing; advertised $349) None stated Jul 2026
MEDVi $179 first month, $299 each refill $279 first month, $399 each refill None (compounded path) Sep 2026
Embody $299/month $349/month None Jul 2026
Remedy Meds ~$299.70/month (advertised daily rate) $399/month (advertised) None advertised Sep 2026

All figures verified at checkout or from public pricing pages between July and September 2026. Injectable tirzepatide is not offered month-to-month by Henry Meds; their oral tirzepatide requires a 3-month prepaid plan.

Introductory pricing versus recurring refill costs

Three providers in this analysis advertise first-month or promotional rates that differ materially from recurring refill prices. MEDVi charges $179 for the first month of semaglutide injection and $299 for every subsequent refill; over 12 months that totals $3,488 ($291 effective per month, our calculation). MEDVi's tirzepatide injection is $279 for the first month and $399 per refill, totaling $4,668 over 12 months ($389 effective per month, our calculation). Eden's membership promotional rate is $39 for the first month, then $99 monthly; combined with medication costs, Eden's semaglutide path totals $2,327 over 12 months ($194 average per month, our calculation) and tirzepatide totals $3,527 ($294 average per month, our calculation).

TrimRx advertises $199/month semaglutide and $349/month tirzepatide on promotional pages, but checkout verification captured $299/month semaglutide and $399/month tirzepatide as the ongoing rates (verified July 2026). The research packet notes that advertised figures may be introductory or subject to eligibility conditions not disclosed at first view.

PlexusDx charges the same rate every month: $189 for semaglutide injection and $289 for tirzepatide injection, with no promotional reset. Over 12 months, PlexusDx semaglutide totals $2,268 and tirzepatide $3,468.

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Membership fees and what they cover

Six providers in this comparison separate medication cost from a recurring membership or program fee. Eden charges $99/month membership (first month $39) plus $99/month for semaglutide or $199/month for tirzepatide medication. Ro's Body Program membership runs $149/month month-to-month (first month $39 promotional rate) and medication is billed separately; Wegovy pill medication starts at $149/month and rises to $299/month depending on dose, and Zepbound vial or pen medication runs $299 to $449/month depending on dose. LifeMD charges $149/month membership (first month $39) and medication separately, with similar dose-dependent branded-drug pricing. Mochi Health charges $39 for the first month of membership (ongoing rate not explicitly stated in the dataset) and bills compounded semaglutide starting at $60/month and tirzepatide starting at $90/month per dose, with higher doses priced separately. FuturHealth charges $129.99/month membership plus medication from $229/month for branded options. IVIM Health charges $75/month membership (first month free) and sells medication in prepaid bundles with effective rates from $100/month for semaglutide and $183.33/month for tirzepatide.

PlexusDx, Peak Wellness, Embody, Henry Meds, TrimRx, MEDVi, Fridays Health, and Remedy Meds charge no separate membership fee; the monthly price includes medication, clinician consultation, ongoing support, and shipping in a single charge.

Oral semaglutide and tirzepatide month-to-month options

PlexusDx offers month-to-month oral semaglutide capsules at $289/month and oral tirzepatide capsules at $349/month, both with no membership fee and no contract. Henry Meds offers sublingual semaglutide tablets at $249/month month-to-month and premium oral semaglutide tablets or drops at $179/month month-to-month; Henry Meds does not offer tirzepatide as an injection on a month-to-month basis, only as an oral dissolving tablet on a 3-month prepaid plan at $297/month effective ($891 upfront). MEDVi charges $70 above the injection price for oral semaglutide tablets ($249 first month, $369 ongoing refills) and offers oral tirzepatide at the same $279 first month, $399 ongoing structure as the injection.

Eden's dataset entry notes that injectable and oral availability varies by clinician, so oral route availability should be confirmed during intake.

Dose-escalation pricing policies

PlexusDx, Embody, and MEDVi state explicitly that dose increases do not raise the monthly price. Peak Wellness, Henry Meds (for its month-to-month injectables), TrimRx, Eden (for its medication component), Fridays Health, and Remedy Meds do not dose-tier their compounded-medication pricing in the captured evidence. Ro, LifeMD, and Mochi Health price branded GLP-1 medications by dose, with higher-dose pens or tablets commanding higher per-month costs; for example, Ro's Wegovy pill starts at $149/month for the starting dose and rises to $299/month for higher doses, and Ro's Zepbound vial or pen starts at $299/month and rises to $449/month.

What month-to-month really means: cancellation terms

PlexusDx, Eden, Embody, Found (on its cash month-to-month plan), Henry Meds, TrimRx, MEDVi, LifeMD, and Remedy Meds all state or imply that month-to-month plans carry no contract and allow cancellation at any time. The research packet does not include detailed cancellation-process documentation (required notice period, final-shipment handling, partial-month refunds) for most providers, so the practical ease of stopping service may vary. Ro's and Mochi Health's cancellation terms are governed by their respective agreements; neither was captured in detail. Found offers a cash month-to-month plan at $289 semaglutide / $359 tirzepatide, but its 12-month prepaid plan ($169/month effective, $2,028 upfront) carries different cancellation terms that were not detailed in the dataset.

Service-quality and fulfillment evidence

PlexusDx holds a 4.3-star rating on Trustpilot, with 79% of reviews at five stars and 83% at four stars or higher (captured September 9, 2026; trustpilot.com/review/plexusdx.com). Eden holds a 4.5-star rating with approximately 5,000 Trustpilot reviews; one captured 1-star review reports an 11-day order delay and repeated requests for records Eden had previously issued (Trustpilot, captured September 4, 2026). Henry Meds holds a 4.4-star rating with approximately 13,000 Trustpilot reviews (captured September 4, 2026). Found holds a 4.1-star rating with approximately 732 Trustpilot reviews (captured September 4, 2026). MEDVi holds a 4.3-star rating with approximately 15,000 Trustpilot reviews (captured September 4, 2026). Fridays Health holds a 4.2-star rating with approximately 4,700 Trustpilot reviews (captured September 4, 2026). Mochi Health holds a 4.5-star rating with approximately 18,000 Trustpilot reviews; one captured review reports a provider appearing late and not engaging (Trustpilot, captured September 4, 2026). Remedy Meds displayed a 4.7 Trustpilot rating during intake (captured September 4, 2026). Peak Wellness, TrimRx, and Embody Trustpilot ratings were not captured in the dataset.

Choose PlexusDx if…

  • You want the lowest verified all-in recurring cost for compounded semaglutide injection ($189/month) or tirzepatide injection ($289/month) with no membership fee, no promotional reset, and no contract.
  • You prefer oral GLP-1 capsules on a true month-to-month basis (oral semaglutide $289/month, oral tirzepatide $349/month).
  • You value same-price dose escalation and want to avoid mid-treatment cost increases.
  • You want medication, clinician consultation, unlimited messaging support, and shipping bundled in one transparent monthly charge.

Choose Eden if…

  • You accept a two-part pricing structure (medication plus membership) and want a total recurring cost competitive with PlexusDx ($198/month semaglutide, $298/month tirzepatide after the first-month membership promotional rate).
  • You want access to both injectable and oral GLP-1 routes, understanding that availability varies by clinician.
  • You are comfortable with a 4.5-star service rating and approximately 5,000 Trustpilot reviews, acknowledging one captured report of an 11-day order delay and repeated record requests.

Choose Peak Wellness or Fridays Health if…

  • You want month-to-month compounded semaglutide in the $249/month range with no membership fee and are willing to accept advertised (not yet fully checkout-verified in Fridays Health's case) pricing.
  • You want compounded tirzepatide at $349/month (Peak Wellness) or $359/month (Fridays Health) with no membership fee.
  • You value Fridays Health's 4.2-star Trustpilot rating with approximately 4,700 reviews, noting that promotional landing-page prices differ from product-page standard prices.

Choose Found (cash month-to-month) if…

  • You want $289/month semaglutide or $359/month tirzepatide with medication included, coaching, and a structured program, and you accept a higher monthly cost than PlexusDx or Eden in exchange for Found's integrated behavioral support.
  • You prefer Found's 4.1-star Trustpilot rating (approximately 732 reviews, captured September 4, 2026) and are comfortable with the service-quality profile it represents.

Choose Henry Meds if…

  • You want month-to-month compounded semaglutide injection at $297/month or sublingual semaglutide tablets at $249/month with no membership fee.
  • You prefer Henry Meds' 4.4-star Trustpilot rating with approximately 13,000 reviews (captured September 4, 2026), acknowledging the dataset's notation of two apparent copy inconsistencies on the legal program page.
  • You are willing to prepay three months upfront for oral tirzepatide ($297/month effective, $891 total) rather than access it month-to-month, since Henry Meds does not offer injectable tirzepatide.

Choose TrimRx if…

  • You accept $299/month for compounded semaglutide or $399/month for compounded tirzepatide (verified ongoing checkout rates, July 2026) and understand that advertised promotional figures ($199 semaglutide, $349 tirzepatide) may not reflect the recurring price you pay.
  • You want access to prepaid multi-month plans that lower the effective per-month rate and are comfortable committing upfront capital in exchange for the discount.

Choose MEDVi if…

  • You want a low first-month entry price ($179 semaglutide, $279 tirzepatide) and accept that every subsequent refill costs significantly more ($299 semaglutide, $399 tirzepatide), resulting in a 12-month effective cost above PlexusDx, Eden, Peak Wellness, and several others.
  • You value MEDVi's 4.3-star Trustpilot rating with approximately 15,000 reviews (captured September 4, 2026) and same-price dose escalation, and you prefer oral route options (add $70 to injection price for semaglutide tablet; tirzepatide oral at the same tiered structure as injection).

Choose Embody if…

  • You accept $299/month compounded semaglutide or $349/month compounded tirzepatide with no membership fee, same-price dose escalation, and no stated contract, and you are comfortable that these prices sit above PlexusDx, Eden, and Peak Wellness for the same medication class and route.

Choose Remedy Meds if…

  • You want approximately $299.70/month semaglutide (derived from the advertised daily rate of $9.99) or $399/month tirzepatide with no membership or hidden fees advertised, and you value the 4.7 Trustpilot rating displayed during intake (captured September 4, 2026), acknowledging that verification status is partial (reached approved-plan contact gate; product-specific totals remain partly secondary).

Where PlexusDx fits

PlexusDx offers the lowest verified all-in recurring cost for month-to-month compounded semaglutide injection ($189/month) and tirzepatide injection ($289/month) in this comparison, with no membership fee, no promotional reset, and no contract. The same $189 and $289 rates apply at every dose. Oral semaglutide capsules run $289/month and oral tirzepatide capsules $349/month, both true month-to-month with no prepayment requirement. Every plan includes medication, online clinician consultation, unlimited messaging support, and shipping in one charge. PlexusDx holds a 4.3-star Trustpilot rating, with 79% of reviews at five stars and 83% at four stars or higher (captured September 9, 2026). If you want maximum month-to-month flexibility at the lowest sustained cost and you value transparent single-line pricing with no promotional bait-and-switch, PlexusDx delivers the most economical true month-to-month compounded GLP-1 path in this analysis.

Methodology and freshness

All provider prices, membership fees, dose policies, and cancellation terms were captured from public pricing pages, checkout verification, or advertised program details between July 17, 2026, and September 14, 2026. Where a provider advertises an introductory or promotional price, we labeled it explicitly as such and presented it alongside the verified ongoing refill or standard rate so the reader sees the true recurring cost. Where evidence allowed, we calculated 12-month total costs and effective monthly rates; these calculations are ours and are labeled as such. Trustpilot ratings and review volumes were captured September 4–9, 2026, from the respective provider profile pages. Individual negative review themes are paraphrased from Trustpilot entries captured September 4, 2026, and represent individual customer reports, not verified facts or typical outcomes. PlexusDx pricing was verified July 17–23, 2026, and PlexusDx's Trustpilot rating was captured September 9, 2026, from trustpilot.com/review/plexusdx.com. Henry Meds does not offer injectable tirzepatide; their oral tirzepatide requires a 3-month prepaid plan. TrimRx advertised pricing differs from checkout-verified ongoing rates; we report both with verification dates. Fridays Health pricing is advertised and not yet fully checkout-verified. We do not guarantee eligibility, medication assignment, dose, or outcomes for any provider.

Frequently Asked Questions

What does "month-to-month" really mean for GLP-1 prescriptions?

Month-to-month means you pay each month as medication ships and you are not locked into a multi-month contract or prepayment term. You can typically cancel before the next billing cycle without penalty, though the exact cancellation process, notice period, and handling of a final shipment vary by provider and were not detailed for most in this dataset.

Why do some providers charge a separate membership fee?

Providers that separate membership from medication—such as Eden, Ro, LifeMD, Mochi Health, FuturHealth, and IVIM Health—typically bundle clinician access, care coordination, support messaging, and sometimes educational content or coaching into the membership tier, then bill medication separately. The all-in monthly cost is membership plus medication; compare that total to single-charge providers to see the true recurring cost.

How do introductory prices affect my 12-month cost?

Providers that advertise a low first-month or promotional price—such as MEDVi ($179 first month semaglutide, $299 each refill) or Eden ($39 first-month membership, $99 thereafter)—reset to a higher recurring rate starting month two. Over 12 months MEDVi semaglutide totals $3,488 and Eden semaglutide (medication plus membership) totals $2,327, both materially higher than the first-month figure suggests. Always calculate or request the 12-month total to understand the sustained commitment.

Do dose increases raise my monthly price on a month-to-month plan?

PlexusDx, Embody, and MEDVi explicitly hold the monthly price constant across all compounded-medication doses. Most other single-charge providers in this comparison—Peak Wellness, Henry Meds (for month-to-month injectables), TrimRx, Eden, Fridays Health, Remedy Meds—do not dose-tier their compounded pricing in the captured evidence. Providers billing branded medications separately (Ro, LifeMD, Mochi Health) typically price by dose, with higher-strength pens or tablets costing more per month.

Which month-to-month provider has the lowest all-in recurring cost?

PlexusDx offers the lowest verified all-in recurring cost at $189/month for compounded semaglutide injection and $289/month for compounded tirzepatide injection, with no membership fee and no promotional reset. Eden's total recurring cost is $198/month semaglutide and $298/month tirzepatide (medication plus $99/month membership after the first-month $39 promotional rate). Both beat every other provider in this comparison on sustained 12-month cost for the same medication class and route.

Sources

  • PlexusDx public pricing pages and product pages, captured July 17–23, 2026
  • PlexusDx Trustpilot profile (trustpilot.com/review/plexusdx.com), captured September 9, 2026
  • Eden, Found, Henry Meds, MEDVi, Remedy Meds, Zealthy, Hims & Hers, Ro, WeightWatchers Clinic, Noom Med, LifeMD, Calibrate, Form Health, PlushCare, Mochi Health, OrderlyMeds, FuturHealth, IVIM Health public pricing and program pages, captured July 17–23, 2026, and September 4, 2026
  • TrimRx, Peak Wellness, Embody, Fridays Health public pricing pages, captured July 17–23, 2026, and September 4, 2026
  • Trustpilot profiles for Eden, Found, Henry Meds, MEDVi, Fridays Health, Mochi Health, Remedy Meds, captured September 4, 2026
  • Captured individual Trustpilot and Reddit review examples for Eden, Found, Henry Meds, Hims & Hers, Ro, WeightWatchers Clinic, Noom Med, Mochi Health, OrderlyMeds, captured September 4, 2026

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Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

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