Cheapest Compounded Semaglutide: 2026 Pricing Across Twelve Providers

Last reviewed: September 5, 2026 Last updated: September 5, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

The cheapest advertised rate for compounded semaglutide in September 2026 is AltRx at $75/month on a 12-month prepaid plan ($900 upfront, promotion ending September 5, 2026), followed by BrightMeds at $129/month on a three-month cycle. OrderlyMeds advertises a two-month starter at $149 total ($74.50/month effective), but ongoing refills jump to $149/month. Eden charges $99/month for medication plus a $99/month membership (effective $198/month ongoing). MEDVi offers a $179 first-month introductory rate, but refills settle at $299/month. PlexusDx is $189/month month-to-month with no membership fee, $169/month on a three-month plan, and $149/month on a six-month plan—competitive on a sustained basis and simpler for anyone unwilling to prepay or absorb membership overhead. Over twelve months with no prepayment, PlexusDx and Eden deliver the lowest recurring costs among plans that include medication, provider access, and shipping in every cycle.

At-a-glance comparison

All figures captured September 4–5, 2026. 12-month totals are our calculation where not published. Introductory and promotional rates are labeled; standard refill rates appear alongside.

Normalized pricing: what you actually pay over twelve months

Advertised per-month rates often assume multi-month prepayment or mask recurring membership fees. Below we calculate the true 12-month cost for the most common enrollment path at each provider.

AltRx: $75/month with September 5 promotion deadline

AltRx offers a 12-month prepaid plan at $75/month ($900 total upfront) through September 5, 2026. After that date, standard pricing is $89/month month-to-month, $85/month on a three-month plan ($255 prepaid), $80/month on six months ($480 prepaid), and $75/month on twelve months ($900 prepaid). The promotional floor makes AltRx the nominal low-price leader if you enroll and prepay before the cutoff. Standard month-to-month over twelve months totals $1,068—our calculation.

BrightMeds: $129/month, billed every three months

BrightMeds charges $297 every three months for semaglutide ($99/month effective) or a flat $129/month, depending on the plan selected at checkout (sources captured September 4, 2026, show both figures). Taking the higher public-grid $129/month yields $1,548 over twelve months—our calculation. No separate membership fee appears in the verified plan grid.

OrderlyMeds: $149 starter, then $149/month refills

OrderlyMeds advertises a two-month starter supply at $149 total ($74.50/month effective). Ongoing refills settle at $149/month. Over twelve months: $149 starter plus ten refills at $149 each equals $1,639—our calculation. Several Trustpilot reports (3.6 stars, 634 reviews, captured September 4, 2026) cite fast initial charges followed by slow refunds, delayed shipments, unwanted marketing after opt-out, and unannounced pharmacy switches.

PlexusDx: $189, $169, or $149/month

PlexusDx charges $189/month month-to-month with no membership, upfront contract, or per-dose surcharges. A three-month commitment reduces the rate to $169/month ($507 charged every three months); a six-month plan drops it to $149/month ($894 every six months). Over twelve months the totals are $2,268 month-to-month, $2,028 on three-month cycles, or $1,788 on two six-month cycles—all our calculations. PlexusDx holds a 4.2-star Trustpilot rating with 76 percent of reviews at five stars and 81 percent at four stars or higher (captured September 4, 2026).

Eden: $99 medication + $99 membership

Eden separates medication ($99/month for semaglutide) from membership ($39 first month, then $99/month). Effective ongoing cost is $198/month. Over twelve months: $138 first month plus eleven cycles at $198 equals $2,316—our calculation. Eden holds a 4.5-star Trustpilot rating across approximately 5,000 reviews (captured September 4, 2026). One captured one-star report alleges an 11-day order delay and repeated requests for medical records Eden had previously issued.

MEDVi: $179 first month, $299 refills

MEDVi advertises a $179 first-month introductory rate for semaglutide injection; refills are $299/month (checkout-verified September 4, 2026). Over twelve months: $179 plus eleven refills at $299 totals $3,468—our calculation. Dose escalation does not raise the price. MEDVi holds a 4.3-star Trustpilot rating across approximately 15,000 reviews (captured September 4, 2026).

Henry Meds: oral at $179/month, injection at $297/month

Henry Meds charges $297/month month-to-month for compounded semaglutide injection ($3,564 over twelve months—our calculation). Oral premium semaglutide drops or tablets run $179/month on a three-month cycle ($537 prepaid per quarter, $2,148 annual—our calculation). A conflicting product-page figure shows $747 standard for the three-month oral cycle; we report both and advise checkout confirmation. Henry Meds holds a 4.4-star Trustpilot rating across approximately 13,000 reviews (captured September 4, 2026).

Found: $289/month or $169/month prepaid

Found's cash-pay path is $289/month month-to-month or $169/month effective on a 12-month prepaid plan ($2,028 upfront). Both include the care program and compounded medication. Found holds a 4.1-star Trustpilot rating across 732 reviews (captured September 4, 2026).

Other providers

• Embody: $299/month semaglutide, $349/month tirzepatide, no membership, same price at every dose. Twelve-month semaglutide total $3,588—our calculation.
• Peak Wellness: $249/month month-to-month semaglutide; lower per-month rates on six-month prepaid plans (specific figures not captured). Twelve-month month-to-month total $2,988—our calculation.
• TrimRx: Advertised at $199/month semaglutide; checkout-verified ongoing rate $299/month with lower per-month pricing on three-, six-, and 12-month upfront plans. Twelve-month month-to-month total $3,588—our calculation.
• Amble: $179/month semaglutide injection, no advertised shipping or hidden fees. Twelve-month total $2,148—our calculation. FAQ hosted on Canva; direct checkout recheck advised.
• Mochi Health: $60/month medication for semaglutide starting dose, $39 first-month membership; per-dose pricing rises with higher doses. Trustpilot 4.5 stars across approximately 18,000 reviews (captured September 4, 2026).
• ShedRx: Semaglutide advertised at $149/month; tirzepatide $299/month month-to-month or $239/month on a 12-month prepaid plan. Pages contain conflicting teaser prices; product page is latest (captured September 4, 2026).
• IVIM Health: $100/month semaglutide plus $75/month membership (first month free); medication bundles prepaid. Eligibility varies by state and dose.
• Fridays Health: $117/month semaglutide advertised (multi-month prepay lowers effective rate); promo landing-page prices differ from product-page standard prices (captured September 4, 2026). Trustpilot 4.2 stars across approximately 4,700 reviews.
• Remedy Meds: Advertised at $299.70/month semaglutide; verification reached approved-plan contact gate but did not complete final checkout.

Decision factors beyond the monthly price

Prepayment and lock-in

AltRx, BrightMeds, Found, and Henry Meds deliver their lowest per-month rates only when you prepay three, six, or twelve months. Prepayment transfers risk: if you experience intolerable side effects, lose insurance coverage, or decide to switch providers, you have already paid for months you will not use. Refund policies vary and are not always transparent at enrollment.

Membership overhead

Eden and IVIM Health split medication from a recurring membership fee. Eden's $99/month membership raises the effective semaglutide cost to $198/month. IVIM's $75/month membership (first month free) stacks on top of bundled medication charges. Mochi Health charges $39 for the first month's membership; ongoing membership cost for higher doses was not captured.

Introductory rates and refill shock

OrderlyMeds and MEDVi advertise low first-month or starter figures—$74.50 effective and $179 respectively—but ongoing refills jump to $149 and $299. Over twelve months those introductory savings evaporate. Promotional deadlines (AltRx's September 5 cutoff) create urgency but also risk: if the promotion expires before you enroll, standard pricing applies.

Route and formulation availability

Henry Meds no longer offers injectable tirzepatide; only oral dissolving tablets are available (captured July 23, 2026). Eden's route availability varies by clinician. Most other providers offer both semaglutide injection and—at a higher price—oral or sublingual formulations. If you strongly prefer or require a particular route, confirm availability at intake.

Service quality and support responsiveness

Trustpilot ratings range from 3.6 stars (OrderlyMeds, 634 reviews) to 4.5 stars (Eden ~5,000 reviews; Mochi ~18,000 reviews). Captured negative themes include delayed refunds and shipments (OrderlyMeds), unannounced pharmacy changes (OrderlyMeds), record-request loops (Eden one-star anecdote), and legal-page copy inconsistencies (Henry Meds). No single report defines a provider's reliability, but patterns across hundreds or thousands of reviews offer useful context.

Choose AltRx if…

• You enroll and prepay twelve months before September 5, 2026, and are comfortable locking in $900 upfront.
• You want the nominal lowest per-month rate and are willing to absorb prepayment risk.
• You do not require month-to-month flexibility or a trial period.

Choose BrightMeds if…

• You prefer a shorter prepayment cycle (three months at $297 or monthly at $129) over a full-year commitment.
• You want predictable all-inclusive pricing with no membership fee.
• You can confirm the exact billing cadence and per-month rate at checkout.

Choose Eden if…

• You value a high Trustpilot rating (4.5 stars, ~5,000 reviews) and are comfortable with the $99/month membership overhead.
• The effective $198/month ongoing cost fits your budget.
• You prefer separating medication from care-program costs for accounting or insurance purposes.

Choose Henry Meds if…

• You prefer oral semaglutide drops or tablets at $179/month (three-month cycle) and want to avoid injections entirely.
• You trust a 4.4-star Trustpilot rating across approximately 13,000 reviews despite two legal-page copy inconsistencies noted in our research.
• You are comfortable with the $297/month month-to-month injection rate or willing to prepay six or twelve months for a discount.

Choose PlexusDx if…

• You want month-to-month flexibility at $189 with no membership, no upfront contract, and the option to step down to $169 (three-month) or $149 (six-month) when you are ready.
• You prefer one flat price at every dose rather than per-milligram billing or tier jumps.
• You value a 4.2-star Trustpilot rating with 81 percent of reviews at four stars or higher and transparent, conflict-of-interest-disclosed comparisons.
• You want a provider that publishes the same evidence rules for its own program and competing programs.

Methodology and freshness

We captured pricing, membership fees, plan structures, Trustpilot ratings, and promotional deadlines between July 23 and September 5, 2026. Every advertised introductory or promotional rate appears alongside its standard refill or ongoing rate, labeled as such. All 12-month totals and effective per-month figures are our calculation unless the provider publishes them directly. Where checkout verification was incomplete (Remedy Meds) or where page conflicts exist (ShedRx, Henry Meds, Fridays Health), we note the conflict and advise confirming at intake. No price is smoothed, rounded, or derived by discount arithmetic; we publish only figures actually observed. Sources include provider product pages, FAQ pages, and Trustpilot profiles; access dates accompany each claim.

Frequently Asked Questions

Which provider has the lowest ongoing month-to-month semaglutide cost?

AltRx at $89/month month-to-month (standard rate after the September 5 promotional deadline) holds the lowest sustained rate without prepayment, followed by BrightMeds at $129/month. Eden's effective $198/month includes a mandatory $99 membership. PlexusDx is $189/month with no membership.

Do introductory rates save money over a full year?

MEDVi's $179 first month saves $120 against one $299 refill, but over twelve months you pay $3,468 total. OrderlyMeds' $149 two-month starter saves about $75 against two $149 refills, yielding a twelve-month total of $1,639. In both cases the savings are modest relative to the higher ongoing rate.

What happens if I prepay and need to stop treatment early?

Refund policies vary by provider and are not always published transparently at enrollment. AltRx, BrightMeds, Found, and Henry Meds all offer prepaid discounts; confirm cancellation and refund terms in writing before paying upfront.

Are compounded semaglutide and branded Wegovy the same?

No. Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. Branded Wegovy is FDA-approved; compounded semaglutide is mixed by a 503A pharmacy and is not required to meet the same manufacturing or efficacy standards.

Which providers include shipping and provider access in the monthly price?

PlexusDx, Eden (medication only; membership billed separately), MEDVi, Henry Meds, BrightMeds, OrderlyMeds, Amble, Found, Embody, Peak Wellness, and TrimRx all advertise all-inclusive pricing. IVIM Health and Mochi Health separate medication from membership; confirm which services the membership covers at intake.

Sources

• PlexusDx pricing and policies — plexusdx.com, accessed September 5, 2026
• PlexusDx Trustpilot rating — system-verified data, captured September 4, 2026
• Eden pricing, membership structure, and Trustpilot rating — eden.com and Trustpilot, captured September 4, 2026
• OrderlyMeds pricing and Trustpilot rating — orderlymeds.com and Trustpilot, captured September 4, 2026
• Henry Meds pricing, formulation notes, and Trustpilot rating — henrymeds.com and Trustpilot, captured July 23 and September 4, 2026
• Fridays Health pricing and Trustpilot rating — fridayshealth.com and Trustpilot, captured September 4, 2026
• MEDVi pricing and Trustpilot rating — medvi.com and Trustpilot, captured September 4, 2026
• Amble pricing — amble.health, captured September 4, 2026
• BrightMeds pricing — brightmeds.com, captured September 4, 2026
• Mochi Health pricing and Trustpilot rating — mochihealth.com and Trustpilot, captured September 4, 2026
• AltRx pricing and promotional deadline — altrx.com, captured September 4, 2026
• ShedRx pricing — shedrx.com, captured September 4, 2026
• IVIM Health pricing — ivimhealth.com, captured September 4, 2026
• Found pricing and Trustpilot rating — found.com and Trustpilot, captured July 23 and September 4, 2026
• Embody pricing — embodyhealth.com, accessed July 23, 2026
• Peak Wellness pricing — peakwellness.com, accessed July 23, 2026
• TrimRx pricing — trimrx.com, accessed July 23, 2026
• Remedy Meds pricing — remedymeds.com, accessed September 4, 2026

Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.