Last reviewed: September 10, 2026 Last updated: September 10, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

PlushCare operates as a telehealth platform that provides clinical visits and prior-authorization support for branded GLP-1 medications—Wegovy, Ozempic, Zepbound, Mounjaro, and Saxenda—but does not include medication in its membership fees. After a free 30-day trial, members pay $19.99/month (or $149/year prepaid, a $12.42/month equivalent) plus a $129 initial visit, and then fill prescriptions through their pharmacy using insurance or cash pay. Labs cost extra. Over 12 months, PlushCare's service fees alone total $348.89 month-to-month or $278 prepaid annually, before any medication or lab expense.

Seven telehealth compounding programs verified at checkout in July 2026 bundle compounded semaglutide or tirzepatide, provider visits, and shipping into a single monthly rate with no separate membership fee. Month-to-month all-in prices for compounded semaglutide injection ranged from $189 (PlexusDx) to $299 (Embody, TrimRx ongoing checkout rate); for compounded tirzepatide injection, from $289 (PlexusDx) to $399 (TrimRx ongoing). If you have insurance coverage and low copays for branded GLP-1s, PlushCare's model may deliver lower net cost. If you're paying cash or face high deductibles, bundled compounding programs typically cost less over 12 months and eliminate prior-authorization delays.

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At-a-glance comparison

Provider Medication Included Membership Fee Month-to-Month Rate 12-Month Cost (MTM)
PlushCare No—pharmacy fill $19.99/mo after free 30 days $129 initial visit + membership $348.89 (service only)
PlexusDx Yes—compounded sema/tirz None $189 sema / $289 tirz $2,268 sema / $3,468 tirz
Eden Yes—compounded sema $99/mo (required) $198 all-in $2,376
Peak Wellness Yes—compounded sema/tirz None $249 sema / $349 tirz $2,988 sema / $4,188 tirz
Found Yes—compounded sema/tirz None $289 sema / $359 tirz (cash) $3,468 sema / $4,308 tirz
Henry Meds Yes—compounded sema None $297 sema $3,564
Embody Yes—compounded sema/tirz None $299 sema / $349 tirz $3,588 sema / $4,188 tirz
TrimRx Yes—compounded sema/tirz None $299 sema / $399 tirz (checkout) $3,588 sema / $4,788 tirz

All competitor pricing verified at checkout July 17–23, 2026; PlushCare pricing captured September 4, 2026. PlushCare 12-month cost reflects service fees only (membership + initial visit); medication and labs are extra and depend on pharmacy pricing or insurance coverage.

Normalized 12-month pricing: service fees vs. all-in medication bundles

PlushCare offers the first 30 days of membership free, after which the monthly membership is $19.99/month or $149/year prepaid (a $12.42/month equivalent). A self-pay initial visit costs $129. Labs are charged separately. Over 12 months on the month-to-month membership, you pay:

  • Initial visit: $129 (one-time)
  • Month 1: $0 (free trial)
  • Months 2–12: $19.99 × 11 = $219.89
  • 12-month total (service only): $348.89
  • Effective monthly (service only): $29.07/month (our calculation)

On the annual prepaid plan, the 12-month total drops to $278 ($129 visit + $149 annual membership), or $23.17/month effective (our calculation). Neither figure includes medication—you fill prescriptions at a pharmacy using insurance or cash pay—or the cost of labs. Branded Wegovy, Ozempic, Zepbound, and Mounjaro list prices range from roughly $900 to over $1,000 per month without insurance; actual out-of-pocket expense depends on your coverage, deductible, and copay tier.

Compounding programs bundle medication, visits, and shipping into one monthly rate. Month-to-month, all-in 12-month costs for compounded semaglutide injection (our calculation):

  • PlexusDx: $189/month → $2,268 over 12 months
  • Eden: $198/month ($99 medication + required $99/month membership) → $2,376 over 12 months
  • Peak Wellness: $249/month → $2,988 over 12 months
  • Found (cash pay): $289/month → $3,468 over 12 months
  • Henry Meds: $297/month → $3,564 over 12 months
  • Embody: $299/month → $3,588 over 12 months
  • TrimRx (checkout ongoing rate): $299/month → $3,588 over 12 months

TrimRx advertises $199 for semaglutide and $349 for tirzepatide, but checkout billing showed ongoing rates of $299 for semaglutide and $399 for tirzepatide (captured July 17–23, 2026). Lower per-month rates are available on prepaid 3-, 6-, and 12-month plans. Found advertises a cash-pay rate of $169/month on a 12-month plan paid upfront ($2,028 total); its month-to-month cash rate is $289 for semaglutide.

For compounded tirzepatide injection, month-to-month 12-month costs (our calculation):

  • PlexusDx: $289/month → $3,468 over 12 months
  • Peak Wellness: $349/month → $4,188 over 12 months
  • Embody: $349/month → $4,188 over 12 months
  • Found (cash pay): $359/month → $4,308 over 12 months
  • TrimRx (checkout ongoing rate): $399/month → $4,788 over 12 months

PlexusDx offers lower per-month rates on prepaid 3-month and 6-month plans: semaglutide injection drops to $169/month on a 3-month plan ($2,028 over 12 months, our calculation) and $149/month on a 6-month plan ($1,788 over 12 months, our calculation); tirzepatide injection drops to $269/month on a 3-month plan ($3,228 over 12 months) and $249/month on a 6-month plan ($2,988 over 12 months). Peak Wellness and TrimRx also offer lower per-month rates on 6-month prepaid plans (captured July 17–23, 2026).

Compounded semaglutide for $189/month, all-in

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When PlushCare's model makes sense

PlushCare works best if you have commercial or government insurance that covers branded GLP-1s for weight management and your copay or coinsurance is low—say, under $50 per month. In that scenario, PlushCare's $19.99/month membership (or $12.42/month prepaid annually) plus your pharmacy copay may total less than any bundled compounding program. The platform provides prior-authorization support, which can shorten approval timelines when insurance requires step therapy or documentation. If your insurance covers the medication, PlushCare's visit and membership fees are the only out-of-pocket service costs.

PlushCare also suits patients who prefer branded FDA-approved medications—Wegovy, Ozempic, Zepbound, Mounjaro, Saxenda—over compounded formulations. Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient.

The model is less economical if you're paying cash at the pharmacy, face a high deductible (several thousand dollars), or fall into a high-copay tier. Branded GLP-1 list prices exceed $900/month, so even a 20 percent coinsurance can push monthly out-of-pocket cost above $180—more than most bundled compounding rates—before counting PlushCare's membership and visit fees.

When bundled compounding programs cost less

If you're self-pay or your insurance plan doesn't cover GLP-1s for weight management, bundled telehealth compounding programs eliminate the pharmacy middleman and deliver predictable monthly costs. No prior authorization, no deductible, no copay tier surprises. The all-in rate you see is the all-in rate you pay, and several verified programs undercut PlushCare's service fees plus typical branded-medication out-of-pocket expense.

Month-to-month, PlexusDx charges $189 for compounded semaglutide injection—$2,268 over 12 months (our calculation)—and includes the provider visit, prescription, medication shipped to your door, and no separate membership fee. Eden's all-in rate is $198/month ($99 medication + $99/month membership, verified at checkout July 17–23, 2026), totaling $2,376 over 12 months. Peak Wellness is $249/month ($2,988 over 12 months), Found's cash month-to-month is $289 ($3,468 over 12 months), Henry Meds $297 ($3,564), Embody $299 ($3,588), and TrimRx's checkout ongoing rate $299 ($3,588).

For tirzepatide injection, PlexusDx is $289/month ($3,468 over 12 months), Peak Wellness and Embody $349 ($4,188), Found $359 ($4,308), and TrimRx's checkout rate $399 ($4,788).

Several programs, including PlexusDx, Peak Wellness, TrimRx, and Found, offer lower per-month rates on prepaid multi-month plans. PlexusDx drops semaglutide injection to $149/month on a 6-month plan ($1,788 over 12 months, our calculation) and tirzepatide injection to $249/month on a 6-month plan ($2,988 over 12 months). Found advertises a 12-month prepaid cash rate of $169/month for semaglutide ($2,028 total upfront).

Route and formulation differences

PlushCare prescribes branded injectable GLP-1s filled at retail or mail-order pharmacies; the patient administers subcutaneous injections weekly (semaglutide, tirzepatide) or daily (Saxenda). All seven bundled compounding competitors verified in July 2026 offer compounded semaglutide or tirzepatide in injectable form; PlexusDx, Found, and some others also offer oral capsule formulations of semaglutide and tirzepatide at different price points. PlexusDx oral semaglutide is $289/month month-to-month, oral tirzepatide $349/month month-to-month (both drop on prepaid plans). Compounded oral capsules are absorbed differently than subcutaneous injections and are not FDA-approved formulations.

Henry Meds offers compounded semaglutide injection at $297/month but lists only an oral dissolving tablet for tirzepatide on its public menu; no monthly injectable tirzepatide rate was published as of July 2026.

Membership structures and cancellation policies

PlushCare charges a recurring membership ($19.99/month or $149/year prepaid) with no minimum commitment; you can cancel anytime (captured September 4, 2026). The first 30 days are free. Eden requires a $99/month membership on top of its $99/month medication cost. PlexusDx, Peak Wellness, Embody, Henry Meds, TrimRx, and Found (cash track) charge no separate membership fee; the published monthly rate is all-in.

Prepaid plans at PlexusDx, Found, Peak Wellness, and TrimRx lower the effective per-month rate but require upfront payment for three, six, or twelve months. Month-to-month plans let you pause or cancel without forfeiting prepaid funds, at the cost of a higher per-month rate.

Choose PlushCare if…

  • You have insurance that covers branded Wegovy, Ozempic, Zepbound, or Mounjaro for weight management and your copay or coinsurance is low (under $50–75/month).
  • You prefer FDA-approved branded medications over compounded formulations.
  • You value prior-authorization support and are willing to wait for insurance approval.
  • You already use a preferred pharmacy and want prescriptions sent there rather than a mail-order compounding pharmacy.
  • You're comfortable budgeting separately for membership, visits, medication, and labs.

Choose a bundled compounding program if…

  • You're paying cash or face a high deductible and want predictable all-in monthly costs with no prior-authorization delays.
  • You want medication, provider visits, and shipping included in one rate with no surprise lab or membership fees.
  • You're willing to use compounded semaglutide or tirzepatide (not FDA-approved but legal when prescribed by a licensed clinician and prepared by a licensed compounding pharmacy).
  • You prefer telehealth convenience and direct-to-door medication delivery over retail pharmacy pickups.

Where PlexusDx fits

PlexusDx works with licensed 503A compounding pharmacies to deliver compounded semaglutide and tirzepatide injection and oral formulations at flat monthly rates with no membership fee. Month-to-month, compounded semaglutide injection is $189, compounded tirzepatide injection $289—the lowest verified month-to-month rates among the seven bundled programs captured in July 2026. Prepaid 6-month plans drop semaglutide injection to $149/month and tirzepatide injection to $249/month. Every dose level—from starting dose through maintenance—costs the same; there are no dose-escalation upcharges.

The published rate includes the online provider visit, prescription review, medication, and shipping. No labs are required before the initial prescription, though a licensed provider may order labs during treatment if clinically indicated. You can pause or cancel month-to-month plans anytime; prepaid plans require upfront payment but deliver the lowest effective per-month cost.

PlexusDx holds a 4.3-star rating on Trustpilot, with 79 percent of reviews at five stars and 83 percent at four stars or higher (captured September 9, 2026; trustpilot.com/review/plexusdx.com).

Methodology and freshness

PlushCare pricing and service details were captured from the company's public website on September 4, 2026. Competitor all-in pricing for Eden, Embody, Found, Henry Meds, Peak Wellness, and TrimRx was verified at checkout between July 17 and July 23, 2026. Every price figure in this article carries its source and capture date. Twelve-month cost calculations and effective per-month rates labeled as "our calculation" are arithmetic derived from verified monthly or prepaid rates; we publish only prices actually observed, never figures derived by applying promotional discounts. Where a program advertises an introductory or prepaid rate, we present it alongside the standard ongoing rate so you see both the entry cost and the recurring cost. This article was written September 10, 2026; confirm current pricing, plan terms, and product availability at each provider's checkout before committing funds.

Frequently Asked Questions

Does PlushCare include medication in its membership fee?

No. PlushCare charges $19.99/month (or $149/year prepaid) for platform access and a $129 initial visit, but medication is filled at a retail or mail-order pharmacy using your insurance or cash pay. The membership covers clinical visits and prior-authorization support; medication and labs are separate expenses.

Which program has the lowest all-in cost for compounded semaglutide?

Among verified month-to-month rates captured July 17–23, 2026, PlexusDx at $189/month ($2,268 over 12 months) and Eden at $198/month ($2,376 over 12 months) were the two lowest all-in compounded semaglutide injection options. Prepaid plans from PlexusDx, Found, and others drop the effective per-month rate further in exchange for upfront payment.

Can I use PlushCare if I don't have insurance?

Yes. PlushCare accepts self-pay patients. You pay the membership fee and initial visit out of pocket, and then fill prescriptions at a pharmacy using cash. Branded GLP-1 list prices exceed $900/month, so total monthly cost (membership + medication) will typically be higher than bundled compounding programs unless you find a manufacturer savings card or patient-assistance program.

Are compounded GLP-1 medications FDA-approved?

No. Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. Compounded semaglutide and tirzepatide are legal when prescribed by a licensed provider and prepared by a licensed compounding pharmacy.

Do any of these programs require labs before starting?

PlushCare may order labs as part of the initial visit or during treatment, charged separately. Among bundled compounding programs, policies vary: some require no labs before the first prescription, others request recent results or order labs during treatment if the provider deems them necessary. Confirm lab requirements and costs during your intake or first visit.

Sources

  • PlexusDx internal product protocol and pricing schedule (current as of September 10, 2026)
  • PlushCare public website, pricing and service pages (captured September 4, 2026, 13:49:55 UTC)
  • PlushCare membership and cancellation policy (captured September 4, 2026, 13:49:55 UTC)
  • Trustpilot.com/review/plexusdx.com (captured September 9, 2026)
  • Competitor checkout verification: Eden, Embody, Found, Henry Meds, Peak Wellness, TrimRx (captured July 17–23, 2026)

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Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

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