Last reviewed: September 24, 2026
Last updated: September 24, 2026
Written by: Jay Hastings, CEO of PlexusDx
Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.
Medically reviewed by: Jayden Lee, PharmD, EMBA
Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.
PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.
The short answer
Sesame Care operates a cash-pay clinician marketplace that includes weight-loss services, but it does not publish itemized all-in pricing for medication, visits, labs, or shipping. As of our September 4, 2026 review of sesamecare.com, the website states that visit and program fees vary and require an intake or location-specific quote to determine final cost. This opacity makes it impossible to budget monthly expenses before enrollment or to perform apples-to-apples comparisons with programs that publish transparent, flat-rate pricing. If predictable monthly costs and no surprise fees matter to you, you will need to complete Sesame Care's intake process to receive a personalized quote—or choose a provider that publishes every line item upfront.
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What we know—and what requires a quote
Sesame Care is a national telehealth marketplace connecting patients with licensed clinicians for cash-pay services, including weight-loss prescriptions. The platform offers branded GLP-1 medications, and program availability varies by location and provider. Our September 4, 2026 site review found no publicly posted breakdown of medication cost per dose, visit fees, lab fees, shipping charges, or membership dues. The website directs prospective patients to complete an intake form or request a location-specific quote to learn total monthly cost.
Because Sesame Care does not itemize these fees publicly, we cannot verify:
- Whether medication is priced per dose tier or at a single rate
- Whether visit fees recur monthly, quarterly, or only at initiation
- Whether lab work is included or billed separately
- Whether shipping is bundled or added per order
- Whether any membership or platform fee sits on top of medication cost
- Whether pricing changes when you move from lower to higher doses
This structure places Sesame Care in a quote-required tier, where final cost emerges only after intake and clinician assignment. For many patients that is acceptable—particularly when shopping for a specific branded medication or when local provider relationships matter. For others, fee opacity complicates budgeting and comparison shopping before committing time to enrollment.
| Fee category |
Sesame Care (as of 2026-09-04) |
PlexusDx (month-to-month, semaglutide injection) |
| Medication |
Not publicly itemized; quote required |
$189/mo, all doses |
| Provider visit |
Varies; quote required |
Included in $189/mo |
| Labs |
Not publicly itemized; quote required |
Included in $189/mo when ordered |
| Shipping |
Not publicly itemized; quote required |
Included in $189/mo |
| Membership or platform fee |
Not publicly itemized; quote required |
None |
| 12-month cost |
Cannot calculate without quote |
$2,268 (our calculation: $189 × 12) |
Sesame Care figures from sesamecare.com captured September 4, 2026. PlexusDx figures current as of publication; tirzepatide injection month-to-month is $289/mo. All PlexusDx prices are flat across dose tiers and include medication, visits, labs when ordered, shipping, and ongoing clinical support—no separate fees.
Why fee transparency matters for GLP-1 therapy
GLP-1 medications—whether branded or compounded semaglutide and tirzepatide—typically require months of dose titration and indefinite continuation for weight maintenance. A program that appears affordable at initiation can become prohibitively expensive if visit fees recur quarterly, if lab panels are billed separately, if shipping is charged per order, or if medication cost jumps when you move from 0.25 mg to 2.4 mg semaglutide. When these fees are bundled into a single published monthly rate, you can model your annual budget with confidence. When they are not, you face uncertainty every billing cycle.
Published, itemized pricing also allows rational comparison. If one provider charges $150/month for medication but adds $75 for the quarterly visit, $40 for labs, and $15 for shipping, the effective monthly cost over 12 months is materially different from a competitor advertising "$150/month all-in." Without public itemization, that math remains hidden until after enrollment.
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What to ask Sesame Care before enrolling
If Sesame Care's marketplace model appeals to you—perhaps because you prefer cash-pay flexibility, want access to a specific branded medication, or value choosing your own clinician—request a written, itemized quote that answers:
-
Medication cost per month: Does the price change when you titrate to a higher dose? Is the medication branded or compounded?
-
Visit frequency and cost: Is the initial consultation a one-time fee? Do follow-up visits recur monthly, quarterly, or on-demand? What does each visit cost?
-
Lab work: Are baseline and monitoring labs included, or billed separately? If separate, what is the fee per panel?
-
Shipping: Is medication shipping included in the monthly cost, or added per order? Is expedited shipping available, and at what cost?
-
Membership or platform fee: Does Sesame Care charge a recurring membership or administrative fee on top of medication and visit costs?
-
Billing cadence: Are you billed monthly, or required to prepay for multi-month supplies?
-
Refund and cancellation policy: Can you pause or cancel without forfeiting prepaid fees?
Requesting this breakdown in writing before enrollment allows you to model your 12-month cost and compare it fairly with published alternatives.
Decision factors: quote-required vs. all-in published pricing
Sesame Care's strengths (where evidence supports them):
- Marketplace access to a range of clinicians, which may offer scheduling flexibility or specialist matching unavailable in single-provider telehealth programs.
- Branded GLP-1 prescription availability, for patients who prefer or require brand-name medications over compounded alternatives.
- Cash-pay model may suit patients who do not want to involve insurance or who are shopping for episodic consultations beyond weight loss.
Sesame Care's gaps (where evidence shows limits):
- No publicly itemized all-in pricing as of September 4, 2026, making upfront budgeting and comparison shopping difficult.
- Visit, lab, medication, and shipping fees not disclosed until intake or quote, which requires time investment before knowing monthly cost.
- No published dose-tier pricing policy, leaving uncertainty about cost changes during titration.
PlexusDx strengths:
- Published, all-inclusive pricing: $189/mo month-to-month for compounded semaglutide injection (all doses), $289/mo for tirzepatide injection, with 3-month and 6-month discounts available.
- No separate fees for visits, labs, shipping, or membership—one flat monthly rate covers everything.
- Same price at every dose tier, eliminating surprise cost increases during titration.
- 4.3-star Trustpilot rating with 79% five-star reviews and 83% four stars or higher, captured September 9, 2026.
PlexusDx limitations:
- Compounded medications only—no branded Ozempic, Wegovy, Mounjaro, or Zepbound. (Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.)
- Entirely virtual care model; no in-person clinic option.
Choose Sesame Care if…
You prefer or require a branded GLP-1 medication, value the flexibility of selecting a specific clinician from a marketplace, and are comfortable receiving a personalized quote after intake rather than seeing all costs published upfront. Sesame Care's cash-pay structure may also suit patients who want episodic consultations or who do not wish to enroll in a subscription weight-loss program. Confirm the total monthly cost—including all visit, lab, medication, and shipping fees—in writing before committing.
Choose PlexusDx if…
You want to see your exact monthly cost before starting intake, prefer a single flat rate that includes medication (compounded semaglutide or tirzepatide), provider visits, labs, and shipping, and value dose-tier price stability so titration never triggers a surprise bill. PlexusDx's month-to-month structure ($189/mo semaglutide injection, $289/mo tirzepatide injection) eliminates guesswork, and 3-month or 6-month commitments lower the per-month rate further. The program works entirely with compounded medications and 503A pharmacies, not branded drugs.
Methodology and freshness
This comparison is current as of September 24, 2026. Sesame Care pricing and fee structure information was captured from sesamecare.com on September 4, 2026. PlexusDx pricing is drawn from published product pages and internal records verified through September 2026. The 12-month cost calculation for PlexusDx ($2,268 for month-to-month semaglutide injection) is our calculation: $189/month × 12 months. We could not calculate a 12-month cost for Sesame Care because no stable monthly rate, visit fee, lab fee, or shipping fee was publicly itemized as of our review date. Trustpilot rating for PlexusDx (4.3 stars, 79% five-star, 83% four stars or higher) was captured from trustpilot.com/review/plexusdx.com on September 9, 2026. Readers should verify current pricing, fee structure, and product availability at checkout, as telehealth programs may update rates, add or remove fee categories, or change included services without notice.
Frequently Asked Questions
Does Sesame Care publish its GLP-1 medication pricing?
No. As of our September 4, 2026 review of sesamecare.com, Sesame Care does not publish itemized all-in pricing for its weight-loss program. Visit fees, medication cost, lab fees, and shipping require an intake or location-specific quote. This means you cannot see your total monthly cost until after you begin the enrollment process and receive a personalized estimate from a clinician on the platform.
What fees should I expect in a GLP-1 weight-loss program?
Typical fees include medication cost (which may vary by dose tier), initial and follow-up provider visits, baseline and monitoring lab panels, shipping, and sometimes a separate membership or platform fee. Some programs bundle all of these into a single monthly rate; others itemize and bill them separately. Always request a written breakdown before enrollment so you can model your 12-month cost accurately and compare options fairly.
Does PlexusDx charge separately for visits, labs, or shipping?
No. PlexusDx's published monthly rates ($189/mo for compounded semaglutide injection month-to-month, $289/mo for tirzepatide injection month-to-month) include medication at any dose tier, all provider visits, labs when clinically indicated, and shipping. There are no membership fees, no per-visit charges, and no surprise bills when you titrate to a higher dose. The price you see is the price you pay, every month.
Can I get branded Ozempic or Wegovy through PlexusDx?
No. PlexusDx prescribes compounded semaglutide and tirzepatide through licensed 503A compounding pharmacies, not branded medications. Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a compounded prescription is appropriate for your individual situation. If you require or prefer a branded GLP-1, you will need a program that offers brand-name prescriptions, such as Sesame Care's marketplace.
How do I compare programs when one publishes pricing and another requires a quote?
Request a written, itemized quote from the quote-required program that breaks out medication, visit, lab, shipping, and membership fees by month. Then calculate the total cost over 12 months (accounting for dose titration if prices change per tier) and compare that figure to the published program's 12-month total. Confirm whether any fees are prepaid, whether visits recur or are one-time, and whether cancellation refunds are available. Published pricing simplifies this process, but a detailed quote levels the playing field.
Sources
- Sesame Care official website, sesamecare.com – accessed September 4, 2026
- PlexusDx product pages and pricing structure – verified September 2026
- Trustpilot review profile for PlexusDx, trustpilot.com/review/plexusdx.com – accessed September 9, 2026
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Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.
Medical and Editorial Standards
Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.
Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.
Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.
Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.
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