Ro vs PlexusDx: GLP-1 cost, reviews (2026)
Ro's monthly membership is $39 the first month, then $149, plus brand-name medication; PlexusDx compounded semaglutide is $149 a month, medication included (Oct 28, 2026). PlexusDx sells an at-home GLP-1 & Peptide Pathways Genetic Test and blood tests, and offers a free 15-minute PharmD consult.
Ro reviews: 3.9/5 on Trustpilot (7,474 reviews) · A+ from the BBB
| Price | PlexusDx | Ro |
|---|---|---|
| Membership month to month | None the plan price includes the medication | $39 first month, then $149/mo |
| Semaglutide month to month | $149/mo compounded | $199/mo Wegovy® pen (brand-name), first 2 months, then $349; plus membership |
| Tirzepatide month to month | $189/mo compounded | $299/mo Zepbound® KwikPen® (brand-name) at 2.5 mg, rising with dose; plus membership |
| 12-month plan | $99/mo compounded semaglutide, $1,188 up front | $74/mo membership only, prepaid; medication billed separately |
- Genetic test
- PlexusDx: At-home GLP-1 & Peptide Pathways Genetic Test, sold separately
- Ro: None in its membership or the sign-up we walked
- Blood tests
- PlexusDx: At-home blood tests, sold separately
- Ro: A lab test if its provider asks: at a Quest location, or an at-home kit bought through Ro for an additional cost
- Medication
- PlexusDx: Compounded semaglutide or tirzepatide; not FDA-approved
- Ro: Brand-name Wegovy® and Zepbound®; FDA-approved
- When you're charged
- PlexusDx: When your prescription goes to the pharmacy
- Ro: $39 at checkout, refunded if you aren't eligible; medication after a provider approves you
- Same at both
- Online intake reviewed by a licensed provider · LegitScript seal on each company's site
What else PlexusDx offers
GLP-1 & Peptide Pathways Genetic Test
150+ genetic insights across 14 health pathways.
$298, or $99 for program members.
See the test →At-home blood tests from $129
Plus supplement packs from $79, built from your results.
See blood tests →The GLP-1 & Peptide Pathways Genetic Test does not select or predict a medication; your provider decides.
What do Ro's reviews say?
As of Oct 29, 2026, Trustpilot rates Ro 3.9 out of 5 and the BBB rates it A+, but its 344 BBB customer reviews average 1.1 out of 5.
Trustpilot
Replies to 86% of negative reviews
- Typically replies within 2 weeks.
- Asks customers to review.
BBB
A+, accredited
- Accredited since July 23, 2018.
- 761 complaints in the past 3 years, 406 in the past 12 months.
- BBB customer reviews average 1.1 out of 5 across 344.
- Complaints on its first page are mostly about the membership fee billed separately from the medication, charges after a cancellation request and prepaid memberships not refundable after a cancellation; Ro responded to 7 of the 10, and 6 are marked resolved.
Both read at source on Oct 29, 2026. Ratings belong to the platforms, not to PlexusDx.
What do Ro and PlexusDx cost on 3- and 6-month plans?
On 3- and 6-month plans, Ro's membership alone is $99 and $89 a month, prepaid, with medication billed separately; PlexusDx semaglutide is $129 and $109 a month, medication included (Oct 28, 2026).
| Plan | PlexusDx | Ro |
|---|---|---|
| Semaglutide 3-month plan | $129/mo compounded, $387 up front | $99/mo membership only; plus Wegovy® pen |
| Semaglutide 6-month plan | $109/mo compounded, $654 up front | $89/mo membership only; plus Wegovy® pen |
| Tirzepatide 3-month plan | $169/mo compounded, $507 up front | $99/mo membership only; plus Zepbound® KwikPen® |
| Tirzepatide 6-month plan | $149/mo compounded, $894 up front | $89/mo membership only; plus Zepbound® KwikPen® |
Is Ro or PlexusDx better?
PlexusDx sells the at-home GLP-1 & Peptide Pathways Genetic Test and blood tests, offers a free PharmD consult and has one price that includes the medication; Ro is better if you want brand-name, FDA-approved medication, coaching or help using insurance.
Choose Ro if…
- You want a brand-name, FDA-approved medication such as Wegovy® or Zepbound®, which PlexusDx does not sell.
- You want help using insurance for the Wegovy® pen, Zepbound® pen or Ozempic®.
- You want up to 24 provider consults a year and 1:1 health coaching in your membership.
Choose PlexusDx if…
- You want the at-home GLP-1 & Peptide Pathways Genetic Test, sold separately.
- You want at-home blood tests, sold separately.
- You want a free 15-minute consult with Dr. Jayden Lee, PharmD, by video or phone.
- You want one plan price that includes the medication and stays the same at every dose.
How do Ro and PlexusDx compare on dose pricing, cancelling, support and formats?
Both renew automatically until you cancel.
Read on Oct 28 and 29, 2026 from each company's own pages.
- Price as your dose rises
- PlexusDx: The same at every dose
- Ro: Its membership stays the same; its medication price rises with dose
- Cancelling
- PlexusDx: Turn off renewal in your patient portal before the next charge
- Ro: In your Ro account, at least 48 hours before your next charge
- Support
- PlexusDx: 24/7 support and clinical chat
- Ro: Unlimited provider messaging, its program page says
- Formats
- PlexusDx: Injection, including a microdose program
- Ro: Brand-name injections: the Wegovy® pen, Zepbound® KwikPen® and Zepbound® pen, and Ozempic®
How are brand-name and compounded GLP-1s different?
Brand-name GLP-1s such as Wegovy® and Zepbound® are FDA-approved medicines made by Novo Nordisk and Eli Lilly; compounded semaglutide and tirzepatide are prepared by a licensed pharmacy for one patient from a prescription and are not FDA-approved.
Both Ro and PlexusDx start with an online intake reviewed by a licensed provider. Ro prescribes brand-name medication, filled by its own pharmacy, a partner pharmacy or one you choose. In the PlexusDx program, a 503A compounding pharmacy, a state-licensed facility that prepares medication for one patient from a valid prescription, fills the prescription and ships it to your door.
Compounded medications are not FDA-approved and are not reviewed by the FDA for safety, quality, or effectiveness. They are a legal, provider-prescribed option prepared by a licensed pharmacy, not a generic or a substitute the FDA has evaluated.
How did we check these prices and reviews?
We walked Ro's sign-up from its GLP-1 page to its membership order summary on Oct 28, 2026, without paying, read its weight-loss pricing page the same day, and read its Terms, refund page, Trustpilot and BBB pages on Oct 29.
At Ro you choose a medication only after a provider approves you, so no medication checkout can be reached before a prescription. The tables show Ro's membership as its checkout showed it and its medication as its pricing page prints it, as two charges, the way Ro shows them. PlexusDx prices come from our product pages.
Who wrote this. The PlexusDx editorial team wrote this page, and Dr. Jayden Lee, PharmD, reviewed it for accuracy.
Our bias. PlexusDx publishes this page and is one of the two programs compared. We show where Ro is ahead, and we update the page when either company changes its prices.
- Ro's website (ro.co)
- Ro's GLP-1 page
- Ro's weight-loss pricing page
- Ro's weight-loss program page
- How Ro's program works
- Ro's Terms of Use
- Ro's returns and refunds page
- Ro on Trustpilot
- Ro on the BBB
- PlexusDx semaglutide injection
- PlexusDx tirzepatide injection
- PlexusDx refund and cancellation policy
- PlexusDx microdose GLP-1
- Hims & Hers vs PlexusDx
Start with a free consult or an online visit
PlexusDx semaglutide is $149 month to month or $99/mo on a 12-month plan; tirzepatide is $189 or $129/mo.
A licensed provider reviews your intake before anything is prescribed.
Start your online visitOr book a free 15-minute consult with Dr. Jayden Lee, PharmDFrequently Asked Questions
How much does Ro cost a month?
At checkout on Oct 28, 2026, Ro's membership was $39 the first month, then $149 a month, with medication billed separately. Its pricing page lists the Wegovy® pen at $199 a month for the first two months, then $349 to $399 by dose, and the Zepbound® KwikPen® from $299. Prepaid memberships are $99, $89 and $74 a month for 3, 6 and 12 months. PlexusDx semaglutide is $149 month to month and tirzepatide $189, medication included.
How much is Ro tirzepatide?
Ro sells tirzepatide as brand-name Zepbound®, and its KwikPen® is $299 to $449 a month by dose, plus the membership (Ro's pricing page, Oct 28, 2026). That is $299 at 2.5 mg, $399 at 5 mg and $449 at 7.5 mg to 15 mg with a manufacturer offer, which needs each refill check-in within 45 days of your last delivery; otherwise a 7.5 mg refill is $499, Ro's FAQ says. PlexusDx compounded tirzepatide is $189 a month at every dose, medication included.
Is Ro cheaper than PlexusDx?
No, not on cash price: Ro's monthly membership alone is $149 after a $39 first month, and PlexusDx semaglutide is $149 a month with the medication included (Oct 28, 2026). Ro bills brand-name medication on top: $199 a month for two months, then $349, for the Wegovy® pen and from $299 for the Zepbound® KwikPen®. Ro's medications are FDA-approved; PlexusDx's semaglutide and tirzepatide are compounded and are not FDA-approved. With insurance that covers the medication, what you pay Ro for it depends on your plan.
How does the Ro weight loss program work?
You complete an online visit and pay $39 for the first month of the Ro Body membership; if a provider approves you, you choose a brand-name GLP-1, billed separately (Oct 28, 2026). Ro refunds the $39 if you aren't eligible. The membership includes unlimited provider messaging, up to 24 provider consults a year, 1:1 health coaching and help using insurance for the medication. At PlexusDx, a licensed provider reviews your online intake, and one plan price covers the provider, prescription, medication and shipping.
Does Ro's price go up with dose?
Its medication price does; its membership does not. Ro's pricing page says "The price of Wegovy increases for higher doses": the Wegovy® pen is $199 a month for the first two months, then $349 from 1 mg, and the Zepbound® KwikPen® rises from $299 with dose. At PlexusDx, your dose may need to go up; your price won't. Checked Oct 28, 2026.
When does Ro charge your card?
Ro charges $39 at checkout and refunds it if you aren't eligible for treatment; the medication is charged after a provider approves you. Its checkout reads "You agree to pay $39 now and if prescribed medication, you'll be automatically charged $149 every month until you cancel, minus any credits." At PlexusDx, cards are charged once your prescription is sent to the pharmacy. Checked Oct 28, 2026.
Can you get a refund from Ro?
Ro refunds the $39 first month if you aren't eligible for treatment, but once paid, its membership fee is non-refundable, its Terms say. Its refund page says prescription products cannot be returned and "all sales are final," and its Terms were last revised April 2, 2026. PlexusDx gives a full refund if you cancel after approval and before your prescription is sent to the pharmacy.
How do I cancel Ro?
In your Ro account, at least 48 hours before your next charge, its checkout and Terms say. Its Terms also allow cancelling by email, and the membership runs to the end of the period you paid for. With PlexusDx, you turn off renewal in your patient portal before the next charge.
Is Ro legit?
Ro (ro.co) is an operating telehealth company run by Roman Health Ventures Inc. of New York. As of Oct 29, 2026, Trustpilot rated Ro 3.9 out of 5 across 7,474 reviews, and the BBB rated it A+ and accredited since 2018, with 406 complaints in the past 12 months and 344 BBB customer reviews averaging 1.1 out of 5. Its site shows a LegitScript Certified seal.
Is Ro a compounding pharmacy?
Ro lists and prices no compounded GLP-1: its weight-loss medications are brand-name and FDA-approved, such as the Wegovy® pen and Zepbound® KwikPen® (Oct 28, 2026). Its Terms say prescriptions are filled by Roman Health Pharmacy, a partner pharmacy or a pharmacy you choose, and allow compounded medication "during national drug shortages." In the PlexusDx program, licensed 503A pharmacies fill prescriptions for compounded semaglutide and tirzepatide, which are not FDA-approved.
Does Ro take insurance?
For some medications, not for the membership: the Wegovy® pen, Zepbound® pen and Ozempic® can be covered by insurance through Ro, and its membership is cash-pay. The Zepbound® KwikPen® is cash-pay only. The prices on this page are Ro's cash prices.
Is Ro or Hims & Hers cheaper?
They list the same membership, $39 the first month, then $149 a month, and the same starting prices for the Wegovy® pen ($199 a month) and Zepbound® ($299), medication only (Oct 28–29, 2026). Ro prints its medication prices by dose (Wegovy® pen $199 for the first two months, then $349 to $399) and sells 3-, 6- and 12-month memberships at $99, $89 and $74 a month, billed up front; Hims & Hers lists "from" prices, not a price for each dose. PlexusDx has no membership fee: semaglutide is $149 month to month and tirzepatide $189; see Hims & Hers vs PlexusDx.
Can I talk to a pharmacist?
Yes. PlexusDx offers a free 15-minute consult with Dr. Jayden Lee, PharmD, by video or phone. It is education and support; a licensed provider makes any prescribing decision.
What does the PlexusDx genetic test do?
The GLP-1 & Peptide Pathways Genetic Test shows how your genes relate to weight management and other peptide-related pathways, with 150+ genetic insights across 14 health pathways from one swab. It does not select or predict a medication; your provider decides. It costs $298, or $99 for program members, and is sold separately from any GLP-1 plan.
PlexusDx tells you about your biology. It does not tell you what to put in your body.