Ro vs PlexusDx: GLP-1 cost, reviews (2026)

Medically reviewed by Dr. Jayden Lee, PharmD · Checked

Ro's monthly membership is $39 the first month, then $149, plus brand-name medication; PlexusDx compounded semaglutide is $149 a month, medication included (Oct 28, 2026). PlexusDx sells an at-home GLP-1 & Peptide Pathways Genetic Test and blood tests, and offers a free 15-minute PharmD consult.

Ro reviews: 3.9/5 on Trustpilot (7,474 reviews) · A+ from the BBB

Ro's membership at checkout and its medication on its pricing page, and PlexusDx checkout prices, Oct 28, 2026. Ro advertises "as low as $74/mo", its 12-month membership; PlexusDx "Starts at $99/mo", its 12-month semaglutide.
PricePlexusDxRo
Membership month to monthNone the plan price includes the medication$39 first month, then $149/mo
Semaglutide month to month$149/mo compounded$199/mo Wegovy® pen (brand-name), first 2 months, then $349; plus membership
Tirzepatide month to month$189/mo compounded$299/mo Zepbound® KwikPen® (brand-name) at 2.5 mg, rising with dose; plus membership
12-month plan $99/mo compounded semaglutide, $1,188 up front$74/mo membership only, prepaid; medication billed separately
Genetic test
PlexusDx: At-home GLP-1 & Peptide Pathways Genetic Test, sold separately
Ro: None in its membership or the sign-up we walked
Blood tests
PlexusDx: At-home blood tests, sold separately
Ro: A lab test if its provider asks: at a Quest location, or an at-home kit bought through Ro for an additional cost
Medication
PlexusDx: Compounded semaglutide or tirzepatide; not FDA-approved
Ro: Brand-name Wegovy® and Zepbound®; FDA-approved
When you're charged
PlexusDx: When your prescription goes to the pharmacy
Ro: $39 at checkout, refunded if you aren't eligible; medication after a provider approves you
Same at both
Online intake reviewed by a licensed provider · LegitScript seal on each company's site

What else PlexusDx offers

GLP-1 & Peptide Pathways Genetic Test

150+ genetic insights across 14 health pathways.

$298, or $99 for program members.

See the test →

Free 15-minute consult with Dr. Jayden Lee, PharmD

By video or phone.

Book a free consult →

At-home blood tests from $129

Plus supplement packs from $79, built from your results.

See blood tests →

The GLP-1 & Peptide Pathways Genetic Test does not select or predict a medication; your provider decides.

What do Ro's reviews say?

As of Oct 29, 2026, Trustpilot rates Ro 3.9 out of 5 and the BBB rates it A+, but its 344 BBB customer reviews average 1.1 out of 5.

Trustpilot

Replies to 86% of negative reviews

  • Typically replies within 2 weeks.
  • Asks customers to review.

Read Ro on Trustpilot →

BBB

A+, accredited

  • Accredited since July 23, 2018.
  • 761 complaints in the past 3 years, 406 in the past 12 months.
  • BBB customer reviews average 1.1 out of 5 across 344.
  • Complaints on its first page are mostly about the membership fee billed separately from the medication, charges after a cancellation request and prepaid memberships not refundable after a cancellation; Ro responded to 7 of the 10, and 6 are marked resolved.

Read the BBB profile →

Both read at source on Oct 29, 2026. Ratings belong to the platforms, not to PlexusDx.

What do Ro and PlexusDx cost on 3- and 6-month plans?

On 3- and 6-month plans, Ro's membership alone is $99 and $89 a month, prepaid, with medication billed separately; PlexusDx semaglutide is $129 and $109 a month, medication included (Oct 28, 2026).

Ro's membership at its plan choice and PlexusDx checkout prices, per month, billed up front, Oct 28, 2026.
PlanPlexusDxRo
Semaglutide 3-month plan$129/mo compounded, $387 up front$99/mo membership only; plus Wegovy® pen
Semaglutide 6-month plan$109/mo compounded, $654 up front$89/mo membership only; plus Wegovy® pen
Tirzepatide 3-month plan$169/mo compounded, $507 up front$99/mo membership only; plus Zepbound® KwikPen®
Tirzepatide 6-month plan$149/mo compounded, $894 up front$89/mo membership only; plus Zepbound® KwikPen®

Is Ro or PlexusDx better?

PlexusDx sells the at-home GLP-1 & Peptide Pathways Genetic Test and blood tests, offers a free PharmD consult and has one price that includes the medication; Ro is better if you want brand-name, FDA-approved medication, coaching or help using insurance.

Choose Ro if…

  • You want a brand-name, FDA-approved medication such as Wegovy® or Zepbound®, which PlexusDx does not sell.
  • You want help using insurance for the Wegovy® pen, Zepbound® pen or Ozempic®.
  • You want up to 24 provider consults a year and 1:1 health coaching in your membership.

Choose PlexusDx if…

  • You want the at-home GLP-1 & Peptide Pathways Genetic Test, sold separately.
  • You want at-home blood tests, sold separately.
  • You want a free 15-minute consult with Dr. Jayden Lee, PharmD, by video or phone.
  • You want one plan price that includes the medication and stays the same at every dose.

How do Ro and PlexusDx compare on dose pricing, cancelling, support and formats?

Both renew automatically until you cancel.

Read on Oct 28 and 29, 2026 from each company's own pages.

Price as your dose rises
PlexusDx: The same at every dose
Ro: Its membership stays the same; its medication price rises with dose
Cancelling
PlexusDx: Turn off renewal in your patient portal before the next charge
Ro: In your Ro account, at least 48 hours before your next charge
Support
PlexusDx: 24/7 support and clinical chat
Ro: Unlimited provider messaging, its program page says
Formats
PlexusDx: Injection, including a microdose program
Ro: Brand-name injections: the Wegovy® pen, Zepbound® KwikPen® and Zepbound® pen, and Ozempic®

How are brand-name and compounded GLP-1s different?

Brand-name GLP-1s such as Wegovy® and Zepbound® are FDA-approved medicines made by Novo Nordisk and Eli Lilly; compounded semaglutide and tirzepatide are prepared by a licensed pharmacy for one patient from a prescription and are not FDA-approved.

Both Ro and PlexusDx start with an online intake reviewed by a licensed provider. Ro prescribes brand-name medication, filled by its own pharmacy, a partner pharmacy or one you choose. In the PlexusDx program, a 503A compounding pharmacy, a state-licensed facility that prepares medication for one patient from a valid prescription, fills the prescription and ships it to your door.

Compounded medications are not FDA-approved and are not reviewed by the FDA for safety, quality, or effectiveness. They are a legal, provider-prescribed option prepared by a licensed pharmacy, not a generic or a substitute the FDA has evaluated.

How did we check these prices and reviews?

We walked Ro's sign-up from its GLP-1 page to its membership order summary on Oct 28, 2026, without paying, read its weight-loss pricing page the same day, and read its Terms, refund page, Trustpilot and BBB pages on Oct 29.

At Ro you choose a medication only after a provider approves you, so no medication checkout can be reached before a prescription. The tables show Ro's membership as its checkout showed it and its medication as its pricing page prints it, as two charges, the way Ro shows them. PlexusDx prices come from our product pages.

Who wrote this. The PlexusDx editorial team wrote this page, and Dr. Jayden Lee, PharmD, reviewed it for accuracy.

Our bias. PlexusDx publishes this page and is one of the two programs compared. We show where Ro is ahead, and we update the page when either company changes its prices.

Start with a free consult or an online visit

PlexusDx semaglutide is $149 month to month or $99/mo on a 12-month plan; tirzepatide is $189 or $129/mo.

A licensed provider reviews your intake before anything is prescribed.

Start your online visitOr book a free 15-minute consult with Dr. Jayden Lee, PharmD

Frequently Asked Questions

How much does Ro cost a month?

At checkout on Oct 28, 2026, Ro's membership was $39 the first month, then $149 a month, with medication billed separately. Its pricing page lists the Wegovy® pen at $199 a month for the first two months, then $349 to $399 by dose, and the Zepbound® KwikPen® from $299. Prepaid memberships are $99, $89 and $74 a month for 3, 6 and 12 months. PlexusDx semaglutide is $149 month to month and tirzepatide $189, medication included.

How much is Ro tirzepatide?

Ro sells tirzepatide as brand-name Zepbound®, and its KwikPen® is $299 to $449 a month by dose, plus the membership (Ro's pricing page, Oct 28, 2026). That is $299 at 2.5 mg, $399 at 5 mg and $449 at 7.5 mg to 15 mg with a manufacturer offer, which needs each refill check-in within 45 days of your last delivery; otherwise a 7.5 mg refill is $499, Ro's FAQ says. PlexusDx compounded tirzepatide is $189 a month at every dose, medication included.

Is Ro cheaper than PlexusDx?

No, not on cash price: Ro's monthly membership alone is $149 after a $39 first month, and PlexusDx semaglutide is $149 a month with the medication included (Oct 28, 2026). Ro bills brand-name medication on top: $199 a month for two months, then $349, for the Wegovy® pen and from $299 for the Zepbound® KwikPen®. Ro's medications are FDA-approved; PlexusDx's semaglutide and tirzepatide are compounded and are not FDA-approved. With insurance that covers the medication, what you pay Ro for it depends on your plan.

How does the Ro weight loss program work?

You complete an online visit and pay $39 for the first month of the Ro Body membership; if a provider approves you, you choose a brand-name GLP-1, billed separately (Oct 28, 2026). Ro refunds the $39 if you aren't eligible. The membership includes unlimited provider messaging, up to 24 provider consults a year, 1:1 health coaching and help using insurance for the medication. At PlexusDx, a licensed provider reviews your online intake, and one plan price covers the provider, prescription, medication and shipping.

Does Ro's price go up with dose?

Its medication price does; its membership does not. Ro's pricing page says "The price of Wegovy increases for higher doses": the Wegovy® pen is $199 a month for the first two months, then $349 from 1 mg, and the Zepbound® KwikPen® rises from $299 with dose. At PlexusDx, your dose may need to go up; your price won't. Checked Oct 28, 2026.

When does Ro charge your card?

Ro charges $39 at checkout and refunds it if you aren't eligible for treatment; the medication is charged after a provider approves you. Its checkout reads "You agree to pay $39 now and if prescribed medication, you'll be automatically charged $149 every month until you cancel, minus any credits." At PlexusDx, cards are charged once your prescription is sent to the pharmacy. Checked Oct 28, 2026.

Can you get a refund from Ro?

Ro refunds the $39 first month if you aren't eligible for treatment, but once paid, its membership fee is non-refundable, its Terms say. Its refund page says prescription products cannot be returned and "all sales are final," and its Terms were last revised April 2, 2026. PlexusDx gives a full refund if you cancel after approval and before your prescription is sent to the pharmacy.

How do I cancel Ro?

In your Ro account, at least 48 hours before your next charge, its checkout and Terms say. Its Terms also allow cancelling by email, and the membership runs to the end of the period you paid for. With PlexusDx, you turn off renewal in your patient portal before the next charge.

Is Ro legit?

Ro (ro.co) is an operating telehealth company run by Roman Health Ventures Inc. of New York. As of Oct 29, 2026, Trustpilot rated Ro 3.9 out of 5 across 7,474 reviews, and the BBB rated it A+ and accredited since 2018, with 406 complaints in the past 12 months and 344 BBB customer reviews averaging 1.1 out of 5. Its site shows a LegitScript Certified seal.

Is Ro a compounding pharmacy?

Ro lists and prices no compounded GLP-1: its weight-loss medications are brand-name and FDA-approved, such as the Wegovy® pen and Zepbound® KwikPen® (Oct 28, 2026). Its Terms say prescriptions are filled by Roman Health Pharmacy, a partner pharmacy or a pharmacy you choose, and allow compounded medication "during national drug shortages." In the PlexusDx program, licensed 503A pharmacies fill prescriptions for compounded semaglutide and tirzepatide, which are not FDA-approved.

Does Ro take insurance?

For some medications, not for the membership: the Wegovy® pen, Zepbound® pen and Ozempic® can be covered by insurance through Ro, and its membership is cash-pay. The Zepbound® KwikPen® is cash-pay only. The prices on this page are Ro's cash prices.

Is Ro or Hims & Hers cheaper?

They list the same membership, $39 the first month, then $149 a month, and the same starting prices for the Wegovy® pen ($199 a month) and Zepbound® ($299), medication only (Oct 28–29, 2026). Ro prints its medication prices by dose (Wegovy® pen $199 for the first two months, then $349 to $399) and sells 3-, 6- and 12-month memberships at $99, $89 and $74 a month, billed up front; Hims & Hers lists "from" prices, not a price for each dose. PlexusDx has no membership fee: semaglutide is $149 month to month and tirzepatide $189; see Hims & Hers vs PlexusDx.

Can I talk to a pharmacist?

Yes. PlexusDx offers a free 15-minute consult with Dr. Jayden Lee, PharmD, by video or phone. It is education and support; a licensed provider makes any prescribing decision.

What does the PlexusDx genetic test do?

The GLP-1 & Peptide Pathways Genetic Test shows how your genes relate to weight management and other peptide-related pathways, with 150+ genetic insights across 14 health pathways from one swab. It does not select or predict a medication; your provider decides. It costs $298, or $99 for program members, and is sold separately from any GLP-1 plan.

PlexusDx tells you about your biology. It does not tell you what to put in your body.

Important information about your prescription program. PlexusDx connects patients with an independent network of U.S.-licensed clinicians through a state-licensed telehealth platform. A prescription is issued only if a licensed provider determines it is appropriate. Compounded medications are not FDA-approved and are not reviewed by the FDA for safety, quality, or effectiveness. Novo Nordisk, Inc. is the only U.S. company with FDA-approved products containing semaglutide (Rybelsus®, Ozempic®, Wegovy®). Lilly USA, LLC is the only U.S. company with FDA-approved products containing tirzepatide (Zepbound®, Mounjaro®). Rybelsus®, Ozempic®, and Wegovy® are registered trademarks of Novo Nordisk, Inc.; Zepbound® and Mounjaro® are registered trademarks of Eli Lilly and Company. KwikPen® is a registered trademark of Eli Lilly and Company. PlexusDx is not affiliated with, endorsed by, or sponsored by Novo Nordisk, Inc. or Eli Lilly and Company. This page compares publicly available program information as of October 2026 and is updated periodically; prices and offerings may change. It is not medical advice — consult a qualified healthcare provider before beginning any treatment. Competitor names and prices are the property of their respective owners and are cited for comparison only.