Last reviewed: September 14, 2026 Last updated: September 14, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

ReflexMD's compounded tirzepatide injection costs $399 per month on a month-to-month basis, verified at checkout September 4, 2026. That rate includes the provider consultation and medication with no separate membership fee and no long-term contract required. ReflexMD does not publish multi-month commitment pricing for tirzepatide. Over 12 months at the standard rate, total cost reaches $4,788. PlexusDx offers compounded tirzepatide injection at $289 per month on a month-to-month basis—$110 per month less than ReflexMD—or $269/month with a 3-month commitment and $249/month with a 6-month commitment. PlexusDx also charges the same price at every dose, holds a 4.3-star Trustpilot rating (79% five-star, 83% four-star or higher, captured September 9, 2026), and includes all provider visits, medication, and shipping in the monthly rate with no hidden fees.

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At-a-glance comparison

Feature ReflexMD PlexusDx
Tirzepatide month-to-month $399/month $289/month
Multi-month commitment options None documented $269/mo (3-month)
$249/mo (6-month)
Membership / service fee $0 $0
Provider visit included Yes Yes
Same price at every dose Not documented Yes
12-month cost (MTM) $4,788 $3,468
Trustpilot rating Profile exists; rating not captured 4.3 stars (79% five-star)

ReflexMD pricing captured September 4, 2026 from checkout verification; PlexusDx pricing current as of September 14, 2026.

ReflexMD tirzepatide pricing breakdown

ReflexMD advertises and charges $399 per month for compounded tirzepatide injection on a month-to-month billing cycle with a one-month supply per shipment. The company's website notes no long-term contract is required, and checkout verification confirmed the $399 rate with no separate membership fee added at purchase (captured September 4, 2026). The monthly charge includes the provider consultation and medication; ReflexMD states "no hidden costs" in its service terms.

ReflexMD does not publish multi-month commitment pricing for tirzepatide. The only documented rate is the $399 month-to-month standard. The company also offers compounded semaglutide injection at $299/month and oral weight-control tablets at $199/month, though the exact formulation of the oral product was not verified in this review.

Evidence conflict: affiliate pricing claims

During research, affiliate pages associated with ReflexMD showed advertised introductory rates lower than the standard checkout-verified figures—particularly for semaglutide, where some affiliate pages advertised rates as low as $199/month while the checkout-verified standard rate is $299/month. No promotional or affiliate rate for tirzepatide was captured; the $399/month figure is the only documented tirzepatide price. Because checkout verification is the most reliable pricing signal, this article leads with the verified $399 standard rate. Readers should confirm final pricing at checkout and ask the ReflexMD support team whether any introductory or promotional rates apply to new enrollments.

Normalized 12-month cost comparison

To compare ongoing expense across providers, we calculate total cost over 12 months using each program's standard month-to-month rate. All figures below are our calculations based on the documented monthly rates.

ReflexMD tirzepatide (month-to-month)

  • Monthly rate: $399
  • 12-month total: $399 × 12 = $4,788
  • Effective monthly cost: $399

PlexusDx tirzepatide (month-to-month)

  • Monthly rate: $289
  • 12-month total: $289 × 12 = $3,468
  • Effective monthly cost: $289
  • Monthly savings vs ReflexMD: $399 − $289 = $110/month ($1,320 over 12 months)

PlexusDx tirzepatide (3-month commitment)

  • Monthly rate: $269
  • 12-month total: $269 × 12 = $3,228
  • Effective monthly cost: $269
  • Monthly savings vs ReflexMD: $399 − $269 = $130/month ($1,560 over 12 months)

PlexusDx tirzepatide (6-month commitment)

  • Monthly rate: $249
  • 12-month total: $249 × 12 = $2,988
  • Effective monthly cost: $249
  • Monthly savings vs ReflexMD: $399 − $249 = $150/month ($1,800 over 12 months)

PlexusDx's month-to-month tirzepatide plan costs $110 per month less than ReflexMD's standard rate, with no prepayment required. PlexusDx's 6-month commitment option widens the gap to $150/month—a difference of $1,800 over a year. Both programs include provider consultations, medication, and shipping with no separate membership fee.

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What's included in each plan

ReflexMD

  • Compounded tirzepatide injection, one-month supply
  • Provider consultation (initial and ongoing)
  • Medication shipped monthly
  • No separate membership fee
  • Month-to-month billing with no long-term contract advertised

ReflexMD's website states "no hidden costs," and checkout verification in September 2026 showed the $399 charge with no additional line items. The program does not publish refill protocols, cancellation terms, or dose-escalation pricing in publicly accessible materials.

PlexusDx

  • Compounded tirzepatide injection (same price at every dose)
  • Provider visit (initial and follow-up care)
  • Medication and shipping included
  • No membership fee, no hidden charges
  • Month-to-month billing or discounted multi-month commitments
  • 4.3-star Trustpilot rating with 79% five-star reviews (captured September 9, 2026)

Decision factors

Price transparency and multi-month options

ReflexMD publishes a single $399/month rate with no documented multi-month commitment pricing. PlexusDx offers three clearly itemized tiers: $289 month-to-month, $269 with a 3-month commitment, and $249 with a 6-month commitment. The absence of promotional or affiliate pricing at checkout for ReflexMD simplifies comparison but leaves month-to-month enrollees paying the full standard rate every cycle. PlexusDx's tiered structure lets cost-sensitive patients lock in savings without prepayment—each monthly charge reflects the commitment-tier rate, not an upfront lump sum.

Same price at every dose

PlexusDx charges the same monthly rate regardless of tirzepatide dose, which matters during escalation. A patient moving from 2.5 mg to 10 mg pays $289/month (or the commitment rate) at every step. ReflexMD does not publish dose-specific pricing, so patients should confirm with the support team whether the $399/month rate holds constant across the dose range or adjusts at higher maintenance doses.

Service track record

PlexusDx holds a verified 4.3-star rating on Trustpilot, with 79% of reviews at five stars and 83% at four stars or higher (captured September 9, 2026; trustpilot.com/review/plexusdx.com). ReflexMD maintains a Trustpilot profile, but no rating or review volume was captured during research in September 2026. Without published review data, prospective patients may find it harder to assess ReflexMD's support responsiveness, shipping reliability, or prescription-transfer process before enrollment.

Regulatory and compounding disclosures

Both ReflexMD and PlexusDx dispense compounded tirzepatide. Compounded medications are not FDA-approved. The FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies. ReflexMD's regulatory status is documented as compounded/not FDA-approved (captured September 4, 2026), though the specific compounding-pharmacy network type was not verified in this review.

Choose ReflexMD if…

  • You prefer a single published rate with no multi-month commitment decision at enrollment.
  • You value a "no hidden costs" service claim and are comfortable verifying that all provider visits, shipping, and ancillary fees remain included over time.
  • You do not require visibility into patient reviews or service ratings before starting treatment.

ReflexMD's straightforward $399/month structure may appeal to patients who prioritize simplicity over cost optimization and are willing to pay a premium for month-to-month flexibility without evaluating commitment-tier alternatives.

Choose PlexusDx if…

  • You want the lowest documented month-to-month tirzepatide rate among the two programs—$289/month, $110 less than ReflexMD.
  • You prefer transparent multi-month commitment options that deliver further savings ($269/month at 3 months, $249/month at 6 months) without prepayment.
  • You value same-price-at-every-dose simplicity during escalation and maintenance.
  • You want to review a verified service track record (4.3-star Trustpilot rating, 79% five-star) before enrollment.
  • You want confirmation that all provider visits, medication, and shipping remain bundled in the monthly rate with no membership fee and no hidden charges.

PlexusDx offers a measurably lower cost structure—saving $1,320 per year on a month-to-month basis and up to $1,800 per year with a 6-month commitment—alongside transparent dose-invariant pricing and a documented service reputation.

Methodology and freshness

ReflexMD pricing, fee structure, and service terms were captured September 4, 2026, from checkout verification and publicly accessible service pages. The $399/month tirzepatide rate, zero-membership-fee claim, and monthly billing cycle were verified at the point of purchase simulation. Affiliate-page promotional claims were noted but not verified at checkout; this article leads with checkout-verified standard rates. PlexusDx pricing is current as of September 14, 2026, and drawn from internal pricing structures. Trustpilot ratings for PlexusDx were captured September 9, 2026, from trustpilot.com/review/plexusdx.com. All 12-month cost calculations and savings figures are our calculations based on the documented monthly rates. ReflexMD's Trustpilot profile was identified but rating and review volume were not captured. Readers should confirm all pricing, dose policies, cancellation terms, and service inclusions at checkout before enrollment, particularly given the documented evidence conflict between affiliate-advertised rates and checkout-verified rates.

Frequently Asked Questions

Does ReflexMD charge extra fees beyond the $399/month tirzepatide rate?

ReflexMD advertises "no hidden costs" and checkout verification in September 2026 showed the $399 charge with no separate membership fee or additional line items at purchase. The monthly rate includes provider consultation and medication. Patients should confirm with ReflexMD support whether follow-up visits, shipping, or dose adjustments incur separate charges over time.

Does ReflexMD offer multi-month commitment discounts for tirzepatide?

No multi-month commitment pricing for tirzepatide is documented in ReflexMD's publicly accessible materials or checkout flow as of September 4, 2026. The only published rate is $399 per month on a month-to-month billing cycle. Patients interested in commitment-tier savings may contact ReflexMD directly to ask whether unpublished options exist.

How much do I save choosing PlexusDx over ReflexMD for tirzepatide?

PlexusDx's month-to-month tirzepatide injection costs $289/month, which is $110 per month less than ReflexMD's $399 rate—a savings of $1,320 over 12 months. PlexusDx's 3-month commitment plan ($269/month) saves $130/month ($1,560/year), and the 6-month plan ($249/month) saves $150/month ($1,800/year). All figures are our calculations based on documented standard rates.

Does the ReflexMD tirzepatide price change at higher doses?

ReflexMD does not publish dose-specific pricing in its publicly accessible materials. The $399/month rate is advertised as the standard tirzepatide cost, but whether that figure holds constant from 2.5 mg through 15 mg maintenance doses is not documented. Patients should confirm dose-escalation pricing with ReflexMD support before enrollment to avoid surprise charges during titration.

Are ReflexMD and PlexusDx tirzepatide injections FDA-approved?

No. Both providers dispense compounded tirzepatide, which is not FDA-approved. The FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies; ReflexMD's compounding-pharmacy network type was not verified in this review.

Sources

  • ReflexMD tirzepatide pricing, fee structure, and service terms – captured September 4, 2026, from checkout verification and public service pages
  • ReflexMD affiliate-page promotional claims – noted September 4, 2026; not verified at checkout
  • PlexusDx tirzepatide injection pricing and policy – internal pricing structures, current as of September 14, 2026
  • PlexusDx Trustpilot rating and review distribution – captured September 9, 2026, from trustpilot.com/review/plexusdx.com
  • ReflexMD Trustpilot profile – identified September 4, 2026; rating and review volume not captured

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Compounded medication disclosure: Compounded medications are not FDA-approved. The FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

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