Last reviewed: September 17, 2026 Last updated: September 17, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

Pomegranate Health advertises compounded semaglutide at $119/month and compounded tirzepatide with B6 at $149/month, both with monthly billing (product pages captured September 4, 2026; pomegranate-health.com). No 3-month, 6-month, or 12-month prepaid plan pricing was observed in available evidence. PlexusDx offers month-to-month billing and prepaid 3-month and 6-month plans: semaglutide injection runs $189/month month-to-month, $169/month on the 3-month plan, or $149/month on the 6-month plan; tirzepatide injection runs $289/month month-to-month, $269/month on the 3-month plan, or $249/month on the 6-month plan. Over twelve months, Pomegranate's advertised monthly rates total $1,428 for semaglutide and $1,788 for tirzepatide (our calculation). PlexusDx's 6-month prepaid plan totals $1,788 for semaglutide and $2,988 for tirzepatide over the same period (our calculation, billed $894 every six months for semaglutide and $1,494 for tirzepatide). Pomegranate's product-page figures come from primary sources but were not verified at full app-based checkout; dose-tier pricing may apply, and historical materials mention a consult deposit. Readers should confirm final pricing, inclusions, and dose policy during checkout with each provider.

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At-a-glance plan comparison

Plan Billing Cadence Semaglutide Tirzepatide 12-Month Total
Pomegranate Health (monthly) Monthly $119/month $149/month $1,428 sema / $1,788 tirz
PlexusDx (month-to-month) Monthly $189/month $289/month $2,268 sema / $3,468 tirz
PlexusDx (3-month prepaid) Every 3 months $169/month ($507 per quarter) $269/month ($807 per quarter) $2,028 sema / $3,228 tirz
PlexusDx (6-month prepaid) Every 6 months $149/month ($894 per half-year) $249/month ($1,494 per half-year) $1,788 sema / $2,988 tirz

Pomegranate Health pricing captured September 4, 2026 from product pages; PlexusDx pricing current as of September 17, 2026. Twelve-month totals are our calculation. Pomegranate figures not verified at final checkout; dose-tier pricing may apply.

Normalized like-for-like cost breakdown

Pomegranate Health: monthly billing only

Pomegranate Health's product pages (checked September 4, 2026) list compounded semaglutide injection at $119/month and compounded tirzepatide with B6 injection at $149/month, both with monthly billing. The site states no membership fee or extra charges (pomegranate-health.com, captured September 4, 2026). Historical materials reference a consult deposit, but current product pages make no mention of upfront fees; readers should confirm whether any deposit or consult charge applies during checkout. Dose-tier pricing details appear in the app but were not captured in full; the advertised $119 and $149 rates may apply only at certain dose levels.

Over twelve months with monthly billing:

  • Semaglutide: $119/month × 12 = $1,428 per year (our calculation)
  • Tirzepatide: $149/month × 12 = $1,788 per year (our calculation)

No 3-month, 6-month, or 12-month prepaid discount plans were documented in the evidence reviewed September 4, 2026. Readers who prefer to prepay for multiple months should confirm directly with Pomegranate Health whether such options exist.

PlexusDx: month-to-month and prepaid plans

PlexusDx offers three billing structures for compounded semaglutide and tirzepatide injection, each with transparent all-inclusive pricing (no membership fees, no separate visit or lab charges):

Month-to-month billing:

  • Semaglutide injection: $189/month → $2,268/year (our calculation)
  • Tirzepatide injection: $289/month → $3,468/year (our calculation)

3-month prepaid plan (billed quarterly):

  • Semaglutide injection: $169/month equivalent, billed $507 every three months → $2,028/year (our calculation)
  • Tirzepatide injection: $269/month equivalent, billed $807 every three months → $3,228/year (our calculation)

6-month prepaid plan (billed every six months):

  • Semaglutide injection: $149/month equivalent, billed $894 every six months → $1,788/year (our calculation)
  • Tirzepatide injection: $249/month equivalent, billed $1,494 every six months → $2,988/year (our calculation)

Every dose of semaglutide or tirzepatide carries the same per-month price at PlexusDx; there are no mid-treatment cost increases when a provider adjusts dose. All plans include the online provider visit, prescription, compounded medication from a licensed 503A pharmacy, and shipping.

Cost difference: Pomegranate monthly vs PlexusDx plans

Pomegranate monthly billing vs PlexusDx month-to-month:

  • Semaglutide: $2,268 (PlexusDx MTM) – $1,428 (Pomegranate) = $840/year lower with Pomegranate (our calculation)
  • Tirzepatide: $3,468 (PlexusDx MTM) – $1,788 (Pomegranate) = $1,680/year lower with Pomegranate (our calculation)

Pomegranate monthly billing vs PlexusDx 6-month prepaid:

  • Semaglutide: $1,788 (PlexusDx 6-mo) – $1,428 (Pomegranate) = $360/year lower with Pomegranate (our calculation)
  • Tirzepatide: $2,988 (PlexusDx 6-mo) – $1,788 (Pomegranate) = $1,200/year lower with Pomegranate (our calculation)

Pomegranate Health's advertised monthly rates are lower than PlexusDx's month-to-month and 6-month prepaid pricing for both medications, based on product-page figures captured September 4, 2026. Those figures have not been verified at final app-based checkout, and dose-tier pricing may apply. Readers should confirm total cost, inclusions, and any upfront deposits during enrollment.

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Decision factors: monthly billing flexibility vs prepaid savings

Pomegranate Health's monthly-only model

Strengths:

  • Advertised per-month rates ($119 semaglutide, $149 tirzepatide) are the lowest documented in this comparison
  • Monthly billing offers cancel-anytime flexibility with no prepaid commitment
  • No membership fee stated on product pages (captured September 4, 2026)

Gaps and verification needs:

  • No prepaid multi-month discount plans observed; readers who prefer to lock in cost over three, six, or twelve months should confirm whether such options exist
  • Product-page pricing was not verified at final app-based checkout; additional fees, deposits, or dose-tier surcharges may apply
  • Dose-tier pricing details live in the app but were not captured in full; the $119/$149 rates may apply only at starter or lower doses
  • Historical materials reference a consult deposit; current status of any upfront charge is unclear
  • No Trustpilot rating, review volume, or negative themes were captured for service-quality comparison

PlexusDx's tiered prepaid structure

Strengths:

  • Three billing options (month-to-month, 3-month prepaid, 6-month prepaid) let users choose commitment level vs discount depth
  • Same per-month price at every dose; no mid-treatment cost increases when a provider titrates up
  • All-inclusive pricing: online visit, prescription, compounded medication, and shipping in one figure; no separate membership, lab, or consult fees
  • Trustpilot rating of 4.3 stars, with 79% of reviews at five stars and 83% at four stars or higher (captured September 9, 2026; trustpilot.com/review/plexusdx.com)

Gaps:

  • Month-to-month and prepaid per-month rates are higher than Pomegranate's advertised monthly billing for both semaglutide and tirzepatide
  • Prepaid plans require upfront payment every three or six months; users who pause or discontinue mid-cycle should confirm refund or credit policy before committing

Choose Pomegranate Health if…

  • You want the lowest advertised per-month rate and monthly billing flexibility with no multi-month prepayment
  • You're comfortable verifying final pricing, dose-tier policy, and any consult or deposit fees during app-based checkout
  • You prefer to avoid prepaid commitments and retain month-to-month cancel-anytime flexibility

Choose PlexusDx if…

  • You want transparent same-price-at-every-dose certainty with no mid-treatment cost increases
  • You prefer prepaid multi-month options (3-month or 6-month) to lock in a per-month rate below month-to-month pricing
  • You value fully verified all-inclusive pricing (visit, prescription, medication, shipping) published at checkout with no app-required verification step
  • You want a provider with a documented Trustpilot rating (4.3 stars, 83% four stars or higher) for service-quality comparison

Methodology and freshness

Pomegranate Health pricing ($119/month semaglutide, $149/month tirzepatide, monthly billing) was captured September 4, 2026 from product pages at pomegranate-health.com. Those figures were not verified at final app-based checkout; dose-tier pricing, consult deposits, and additional fees may apply. No 3-month, 6-month, or 12-month prepaid plan pricing was observed in available evidence as of September 4, 2026. PlexusDx pricing (month-to-month, 3-month prepaid, 6-month prepaid) is current as of September 17, 2026 and reflects live product-page rates. Twelve-month cost totals and cost-difference calculations are our calculation, derived by multiplying per-month rates by twelve. PlexusDx's Trustpilot rating (4.3 stars, 79% five-star reviews, 83% four stars or higher) was captured September 9, 2026 from trustpilot.com/review/plexusdx.com. Readers should confirm final pricing, inclusions, dose policy, and any upfront fees during checkout with each provider.

Frequently Asked Questions

Does Pomegranate Health offer prepaid multi-month plans?

No prepaid 3-month, 6-month, or 12-month discount plans were documented in product-page evidence captured September 4, 2026. Pomegranate Health advertises monthly billing at $119/month for semaglutide and $149/month for tirzepatide. Readers who prefer to prepay for multiple months should confirm directly with Pomegranate whether such options exist.

Are Pomegranate Health's advertised prices the final checkout price?

The $119 semaglutide and $149 tirzepatide figures come from product pages but were not verified at final app-based checkout. Dose-tier pricing may apply, and historical materials mention a consult deposit. Readers should confirm total cost, inclusions, and any upfront fees during enrollment to ensure the advertised monthly rate matches the final charge.

Does PlexusDx charge more at higher doses?

No. PlexusDx maintains the same per-month price at every dose of semaglutide or tirzepatide. If a provider titrates your dose upward during treatment, your monthly cost remains $189 (semaglutide MTM), $169 (semaglutide 3-mo), $149 (semaglutide 6-mo), or the corresponding tirzepatide rate, with no mid-treatment price increases.

How much do I save with PlexusDx's 6-month prepaid plan vs month-to-month?

PlexusDx's 6-month prepaid semaglutide plan runs $149/month (billed $894 every six months), saving $40/month vs the $189 month-to-month rate, or $480/year (our calculation). The 6-month tirzepatide plan runs $249/month (billed $1,494 every six months), saving $40/month vs the $289 month-to-month rate, or $480/year (our calculation).

What is included in PlexusDx's all-inclusive price?

Every PlexusDx plan includes the online provider visit, prescription review, compounded semaglutide or tirzepatide from a licensed 503A pharmacy, and shipping to your door. There are no separate membership fees, lab fees, or visit charges. The single per-month figure covers everything required to receive your medication each month.

Sources

  • Pomegranate Health product pages (pomegranate-health.com), accessed September 4, 2026
  • PlexusDx live pricing (plexusdx.com/products/semaglutide-injection, plexusdx.com/products/tirzepatide-injection), accessed September 17, 2026
  • PlexusDx Trustpilot profile (trustpilot.com/review/plexusdx.com), accessed September 9, 2026

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Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

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