Last reviewed: September 4, 2026 Last updated: September 4, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

GobyMeds sells compounded semaglutide in three-month prepaid bundles ranging from $299 upfront (low-dose) to $499 upfront (high-dose), advertised as $99.67 to $166.33 per month. Compounded tirzepatide is available either as a $399 three-month starter bundle or $299 month-to-month at any dose. PlexusDx charges the same price at every dose: semaglutide month-to-month is $189, tirzepatide is $289, and prepaid multi-month options lower the effective rate further. If you want month-to-month flexibility or will need doses above GobyMeds' low tier, PlexusDx typically costs less over 12 months. If you are certain you will stay on a low starter dose and can prepay $299 upfront, GobyMeds' semaglutide low-tier bundle is the cheaper option for that three-month window.

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At-a-glance comparison

GobyMeds PlexusDx
Semaglutide injection $299–$499 upfront for 3 months (dose-tiered) $189/mo MTM, $169/mo 3-mo prepaid, $149/mo 6-mo prepaid
Tirzepatide injection $299/mo MTM or $399 upfront for 3-mo starter $289/mo MTM, $269/mo 3-mo prepaid, $249/mo 6-mo prepaid
Pricing by dose Tiered (semaglutide); flat (tirzepatide MTM) Same at every dose
Billing term 3-month bundles (semaglutide), MTM or 3-mo (tirzepatide) Month-to-month, 3-month, or 6-month
Membership fee None None
What's included Consult, prescription, supplies, overnight shipping Consult, prescription, medication, supplies, shipping
Regulatory status Compounded, not FDA-approved Compounded, not FDA-approved

GobyMeds data captured 2026-09-04; PlexusDx data captured 2026-09-04. Confirm all pricing at checkout.

Normalized 12-month cost comparison

GobyMeds bundles three months of semaglutide upfront, with the total cost determined by your dose tier. PlexusDx lets you choose month-to-month or prepay for three or six months at a time, charging the same rate regardless of dose.

Semaglutide injection: GobyMeds prepaid bundles

GobyMeds offers three semaglutide tiers, each sold as a three-month upfront bundle:

  • Low tier (0.2–0.4 mg): $299 upfront for 3 months, advertised as $99.67 per month. Over 12 months, four bundles total $1,196 (our calculation), or $99.67 per month prepaid.
  • Mid tier (up to 1.5 mg): $399 upfront for 3 months, advertised as $133 per month. Over 12 months, four bundles total $1,596 (our calculation), or $133 per month prepaid.
  • High tier (up to 2.3 mg): $499 upfront for 3 months, advertised as $166.33 per month. Over 12 months, four bundles total $1,996 (our calculation), or $166.33 per month prepaid.

All figures above are GobyMeds' advertised equivalents for bundles that require the full three-month prepayment. Dose tier determines which bundle you purchase.

Semaglutide injection: PlexusDx month-to-month and prepaid

PlexusDx charges the same price at every dose and offers three payment structures:

  • Month-to-month: $189 per month. Over 12 months, total cost is $2,268 (our calculation).
  • 3-month prepaid: $169 per month prepaid equivalent ($507 upfront every 3 months). Over 12 months, four cycles total $2,028 (our calculation), or $169 per month prepaid.
  • 6-month prepaid: $149 per month prepaid equivalent ($894 upfront every 6 months). Over 12 months, two cycles total $1,788 (our calculation), or $149 per month prepaid.

Semaglutide head-to-head over 12 months

Option Billing term 12-month total Per-month equivalent
GobyMeds low tier (0.2–0.4 mg) 3-month prepaid $1,196 $99.67/mo prepaid
GobyMeds mid tier (up to 1.5 mg) 3-month prepaid $1,596 $133/mo prepaid
GobyMeds high tier (up to 2.3 mg) 3-month prepaid $1,996 $166.33/mo prepaid
PlexusDx (any dose) Month-to-month $2,268 $189/mo
PlexusDx (any dose) 3-month prepaid $2,028 $169/mo prepaid
PlexusDx (any dose) 6-month prepaid $1,788 $149/mo prepaid

All 12-month totals and per-month equivalents are our calculations. GobyMeds pricing verified 2026-09-04; PlexusDx pricing verified 2026-09-04.

If you stay on GobyMeds' low tier for the full year, the annual cost is $1,196—lower than any PlexusDx semaglutide option. However, if your dose rises into the mid or high tier, GobyMeds' 12-month cost climbs to $1,596 or $1,996, both higher than PlexusDx's 6-month prepaid rate of $1,788 and comparable to or more expensive than PlexusDx's 3-month prepaid and month-to-month options. PlexusDx's month-to-month option ($2,268 over 12 months) costs more than GobyMeds' low and mid tiers but less than GobyMeds' high tier, and it carries no upfront commitment.

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Tirzepatide injection: GobyMeds starter and month-to-month

GobyMeds offers two tirzepatide paths:

  • Starter bundle: $399 upfront for 3 months of starter dosing, advertised as $133 per month. What happens after the starter period is not specified in the captured evidence; if you continue at the month-to-month rate, the blended 12-month cost is $3,090 (our calculation): $399 for the first 3 months plus 9 months at $299 each, or $257.50 per month blended.
  • Month-to-month at any dose: $299 per month. Over 12 months, total cost is $3,588 (our calculation).

Tirzepatide injection: PlexusDx month-to-month and prepaid

PlexusDx tirzepatide pricing, same at every dose:

  • Month-to-month: $289 per month. Over 12 months, total cost is $3,468 (our calculation).
  • 3-month prepaid: $269 per month prepaid equivalent ($807 upfront every 3 months). Over 12 months, four cycles total $3,228 (our calculation).
  • 6-month prepaid: $249 per month prepaid equivalent ($1,494 upfront every 6 months). Over 12 months, two cycles total $2,988 (our calculation).

Tirzepatide head-to-head over 12 months

Option Billing term 12-month total Per-month equivalent
GobyMeds starter + 9 mo MTM Mixed $3,090 $257.50/mo blended
GobyMeds month-to-month (any dose) Month-to-month $3,588 $299/mo
PlexusDx (any dose) Month-to-month $3,468 $289/mo
PlexusDx (any dose) 3-month prepaid $3,228 $269/mo prepaid
PlexusDx (any dose) 6-month prepaid $2,988 $249/mo prepaid

All 12-month totals and per-month equivalents are our calculations. GobyMeds pricing verified 2026-09-04; PlexusDx pricing verified 2026-09-04.

PlexusDx's month-to-month tirzepatide is $10 per month less expensive than GobyMeds' month-to-month option over 12 months ($3,468 vs $3,588). PlexusDx's 6-month prepaid option brings the 12-month total down to $2,988, $102 less than the blended GobyMeds starter-plus-ongoing scenario and $600 less than GobyMeds' straight month-to-month path.

Decision factors beyond the monthly rate

Prepayment requirement and dose flexibility

GobyMeds requires a three-month upfront payment for every semaglutide refill, and the price depends on your dose. If your provider increases your dose mid-bundle, you may need to purchase a higher-tier bundle at the next refill. PlexusDx lets you pay month-to-month or choose a prepaid term that fits your cash flow; your price never changes with dose adjustments.

Tirzepatide month-to-month availability

GobyMeds offers a true month-to-month tirzepatide option at $299 per month, which is $10 more per month than PlexusDx's $289 month-to-month rate. Both programs allow you to cancel anytime under a month-to-month plan; verify cancellation terms with each provider before enrollment.

All-inclusive pricing

Both GobyMeds and PlexusDx include the provider visit, prescription, medication, supplies, and shipping in the advertised price. Neither charges a separate membership fee. Confirm at checkout whether any visit, lab, or administrative fees apply to your specific enrollment.

Regulatory and pharmacy status

Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies. GobyMeds dispenses compounded semaglutide and tirzepatide; verify the pharmacy type and licensing with GobyMeds directly.

Choose GobyMeds if…

  • You are starting semaglutide, expect to stay on a low dose (0.2–0.4 mg), and can prepay $299 upfront every three months. GobyMeds' low-tier bundle is the least expensive semaglutide option in this comparison over 12 months ($1,196 total).
  • You prefer a simple prepaid structure and do not anticipate frequent dose changes.
  • You want overnight shipping included as standard (GobyMeds specifies overnight delivery; PlexusDx shipping speed may vary).

Choose PlexusDx if…

  • You want month-to-month flexibility with no upfront commitment. PlexusDx lets you start, pause, or cancel on a rolling monthly basis at $189 for semaglutide or $289 for tirzepatide.
  • You will need mid or high doses of semaglutide. PlexusDx charges $189 per month (or $169/$149 prepaid) regardless of dose, while GobyMeds' mid and high tiers push the effective rate to $133–$166.33 per month prepaid.
  • You prefer tirzepatide and want the lowest 12-month cost. PlexusDx's 6-month prepaid option totals $2,988 over 12 months, compared to GobyMeds' $3,090 blended starter-plus-ongoing or $3,588 straight month-to-month.
  • You value transparent same-at-every-dose pricing and want the option to lock in a lower rate by prepaying three or six months at a time.

Methodology and freshness

GobyMeds pricing, bundle terms, and dose tiers were captured from the provider's public website on 2026-09-04 at 13:49:55 UTC. PlexusDx pricing was verified on 2026-09-04 at 21:36:09 UTC. All 12-month totals, per-month equivalents, and blended rates are our calculations based on the published prices and the stated billing cycles. We performed a Trustpilot and Reddit search for GobyMeds on 2026-09-04; no review volume or complaint themes were indexed. Pricing structures and terms can change; confirm all figures and policies at checkout before enrollment.

Frequently Asked Questions

Does GobyMeds charge the same price at every semaglutide dose?

No. GobyMeds sells semaglutide in three dose-tiered bundles: $299 for low doses (0.2–0.4 mg), $399 for mid doses (up to 1.5 mg), and $499 for high doses (up to 2.3 mg). Each bundle covers three months and must be paid upfront. If your dose increases, your next bundle may cost more.

Can I pay month-to-month with GobyMeds?

GobyMeds offers month-to-month billing for tirzepatide at $299 per month. Semaglutide is sold only in three-month prepaid bundles. PlexusDx offers month-to-month billing for both semaglutide ($189/month) and tirzepatide ($289/month) with no upfront commitment.

Which provider is cheaper for semaglutide over 12 months?

If you stay on GobyMeds' low-dose tier for the full year, the total is $1,196, less expensive than any PlexusDx option. If your dose rises to the mid tier, GobyMeds costs $1,596 over 12 months, more than PlexusDx's 6-month prepaid ($1,788 total) and similar to the 3-month prepaid. The high tier ($1,996) is more expensive than all PlexusDx prepaid options.

Which provider is cheaper for tirzepatide over 12 months?

PlexusDx's 6-month prepaid tirzepatide totals $2,988 over 12 months. GobyMeds' starter bundle plus nine months at the month-to-month rate totals $3,090 (our calculation), and the straight month-to-month path is $3,588. PlexusDx's month-to-month option ($3,468) is also less expensive than GobyMeds' month-to-month.

Are these medications FDA-approved?

No. Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. Both GobyMeds and PlexusDx dispense compounded semaglutide and tirzepatide; PlexusDx works with licensed 503A compounding pharmacies.

Sources

  • PlexusDx product pages and pricing (accessed 2026-09-04)
  • GobyMeds website: program overview and inclusions (accessed 2026-09-04 13:49:55)
  • GobyMeds website: detailed pricing, bundle structure, and dose tiers (accessed 2026-09-04 13:49:55)
  • Trustpilot and Reddit: GobyMeds review search (accessed 2026-09-04 13:49:55)

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Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

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