OatMeds vs 10Rx: Three-Month GLP-1 Packages Compared Head-to-Head

Last reviewed: September 5, 2026 Last updated: September 5, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing competing programs.

The short answer

OatMeds structures its three-month packages as 12-week supplies billed upfront: $297 for semaglutide starter ($99/month prepaid) and $399 for tirzepatide starter ($133/month prepaid). 10Rx offers quarterly packages at $299 for semaglutide with B12 ($99.67/month prepaid) and $450 for tirzepatide with B12 ($150/month prepaid). Both require full upfront payment with no monthly billing option documented for 10Rx. PlexusDx three-month commitment plans run $169/month for semaglutide and $269/month for tirzepatide, billed monthly with no prepayment. Over 12 months OatMeds starter packages total $1,188 semaglutide/$1,596 tirzepatide; 10Rx totals $1,196 semaglutide/$1,800 tirzepatide; PlexusDx totals $2,028 semaglutide/$3,228 tirzepatide. The prepaid models deliver lower annual costs but lock in full quarterly or 12-week payment; PlexusDx spreads cost evenly across 12 months with no upfront commitment beyond the current month.

At-a-glance comparison

OatMeds also offers standard 12-week packages at $399 semaglutide/$499 tirzepatide and monthly billing at $199 semaglutide/$229 tirzepatide. 10Rx's primary pricing page confirmed quarterly structure and inclusions but did not display package totals; the $299/$450 figures come from secondary verification captured September 4, 2026. Readers should confirm at checkout.

Three-month package structures compared head-to-head

OatMeds structures three-month supply as 12-week packages billed upfront. The starter package for compounded semaglutide injection (no additive) costs $297 total, which works out to $99/month prepaid over 12 weeks. The standard package costs $399 total, which works out to $133/month prepaid. For compounded tirzepatide injection (no additive), the starter package is $399 total ($133/month prepaid) and the standard package is $499 total ($166/month prepaid). All figures verified from OatMeds' primary product page, captured September 4, 2026.

10Rx structures three-month supply as quarterly packages billed upfront. Compounded semaglutide injection with B12 costs $299 total, which works out to $99.67/month prepaid over three months. Compounded tirzepatide injection with B12 costs $450 total, which works out to $150/month prepaid. 10Rx states "same package price across available strengths." The quarterly structure and inclusions (medication, clinician evaluation, next-day shipping, support) were confirmed on 10Rx's primary pricing page, but that page did not display the $299 and $450 numeric totals; those figures come from secondary verification captured September 4, 2026. Confirm at checkout.

Both programs require full payment upfront for the three-month supply. Neither OatMeds nor 10Rx charges a separate membership fee. OatMeds also offers monthly billing at $199/month for semaglutide and $229/month for tirzepatide (four-week supply), giving members a choice between prepaid savings and monthly flexibility. No monthly billing option was documented for 10Rx.

Normalized 12-month cost: prepaid packages vs monthly commitment

When you compare three-month packages over a full year, the effective annual cost depends on how many cycles you prepay. The calculations below assume you renew each three-month package for four cycles (12 months total). All per-month figures for prepaid packages are our calculation.

OatMeds 12-week packages over 12 months

• Semaglutide starter (no additive): $297 per 12-week cycle × 4 cycles = $1,188/year ($99/month prepaid).
• Semaglutide standard (no additive): $399 per 12-week cycle × 4 cycles = $1,596/year ($133/month prepaid).
• Tirzepatide starter (no additive): $399 per 12-week cycle × 4 cycles = $1,596/year ($133/month prepaid).
• Tirzepatide standard (no additive): $499 per 12-week cycle × 4 cycles = $1,996/year ($166/month prepaid).

10Rx quarterly packages over 12 months

• Semaglutide with B12: $299 per quarter × 4 quarters = $1,196/year ($99.67/month prepaid).
• Tirzepatide with B12: $450 per quarter × 4 quarters = $1,800/year ($150/month prepaid).

PlexusDx three-month commitment over 12 months

• Semaglutide injection: $169/month × 12 months = $2,028/year.
• Tirzepatide injection: $269/month × 12 months = $3,228/year.

OatMeds starter packages deliver the lowest semaglutide annual cost at $1,188, closely matched by 10Rx at $1,196. For tirzepatide, OatMeds starter is $1,596 and 10Rx is $1,800. PlexusDx costs more annually because it spreads payment evenly over 12 months with no upfront commitment beyond the current month. The prepaid models require $297–$499 cash outlay every 12 weeks (OatMeds) or $299–$450 every quarter (10Rx).

Monthly billing vs prepaid: cash flow and commitment

OatMeds offers a monthly billing option at $199/month for semaglutide (four-week supply, no additive) and $229/month for tirzepatide. Over 12 months, monthly billing totals $2,388 semaglutide or $2,748 tirzepatide—substantially more than the prepaid starter packages but still competitive with PlexusDx for semaglutide ($2,028) and below PlexusDx for tirzepatide ($3,228). Monthly billing spreads cost but forfeits the prepaid discount.

10Rx does not publish a monthly billing rate; the quarterly package appears to be the only structure. This means 10Rx members commit $299 or $450 upfront every three months. Members who prefer to pay monthly without a large upfront commitment may find OatMeds' monthly option or PlexusDx's monthly billing more flexible.

Formulation differences: additives and strength tiers

OatMeds offers three formulation tracks for both semaglutide and tirzepatide: no additive, with B12, and with glycine. The no-additive versions anchor the 12-week package pricing shown above. The B12 and glycine versions are available on monthly billing at an introductory rate of $179/month with a standard refill rate of $199/month (captured September 4, 2026), but 12-week package pricing for these formulations was not documented.

10Rx includes B12 in all compounded semaglutide and tirzepatide injections and states "same package price across available strengths." This flat-strength pricing means a member starting at a lower dose and a member at a higher maintenance dose pay the same $299 or $450 quarterly rate, which simplifies budgeting as dose escalates.

PlexusDx compounds semaglutide and tirzepatide injections without routine additives; clinicians adjust strength as medically appropriate within the same monthly rate.

Decision factors

When prepaid three-month packages make sense

Prepaid packages suit members who can comfortably pay $297–$499 (OatMeds) or $299–$450 (10Rx) every 12 weeks or quarter, prefer the lowest total annual cost, and plan to stay on therapy for at least the prepaid period. The discount over monthly billing is meaningful: OatMeds starter packages save $1,200/year on semaglutide and $1,152/year on tirzepatide compared to its own monthly rate. 10Rx's $1,196 semaglutide annual cost undercuts most competitors. Prepayment works well for members with predictable cash flow and confidence in the program.

When monthly billing provides more flexibility

Monthly billing avoids large upfront outlays and allows easier exit or dose adjustment. OatMeds' $199 semaglutide monthly rate is $2,388/year—higher than its own starter package but lower than PlexusDx and competitive in the broader market. PlexusDx's $169 semaglutide and $269 tirzepatide monthly rates are higher annually than prepaid packages but spread cost evenly and carry no multi-month commitment beyond the initial three-month enrollment period.

Evidence transparency: 10Rx secondary-corroborated totals

10Rx's primary pricing page (captured September 4, 2026) confirmed the quarterly structure, flat-strength policy, and included services (clinician evaluation, next-day shipping, support) but did not display the $299 and $450 package totals. Those figures come from secondary verification captured the same day. This mixed-evidence status does not disqualify the comparison—secondary corroboration is common and acceptable—but readers should confirm package totals at checkout before committing. OatMeds pricing is primary-verified throughout.

Choose OatMeds if…

You want the flexibility to pick no-additive, B12, or glycine formulations; you prefer 12-week prepaid cycles and can budget $297–$499 upfront every three months; or you want the option to switch to monthly billing ($199 semaglutide / $229 tirzepatide) if cash flow changes. OatMeds starter packages deliver among the lowest semaglutide annual costs in the compounded GLP-1 market and offer a clear monthly alternative when flexibility matters more than discount.

Choose 10Rx if…

You prefer B12 included in every injection; you value flat pricing across all dose strengths so your cost stays predictable as you titrate; and you can commit $299 (semaglutide) or $450 (tirzepatide) upfront each quarter. 10Rx's semaglutide annual cost of $1,196 is the lowest in this comparison, and its tirzepatide cost of $1,800 beats PlexusDx by $1,428/year. Confirm the $299/$450 totals at checkout, as these figures are secondary-corroborated.

Where PlexusDx fits

PlexusDx three-month commitment plans run $169/month for semaglutide injection and $269/month for tirzepatide injection, billed monthly with no prepayment. Annual costs are higher—$2,028 semaglutide, $3,228 tirzepatide—but you avoid $300–$500 upfront outlays and retain month-to-month payment flexibility after the initial three-month period. One all-inclusive monthly price covers the provider visit, prescription, compounded medication from a licensed 503A pharmacy, and shipping; no membership fee, no hidden charges. PlexusDx holds a 4.2-star rating on Trustpilot, with 76 percent of reviews at five stars and 81 percent at four stars or higher (captured September 4, 2026). Choose PlexusDx if you prefer predictable monthly budgeting, want to avoid large upfront commitments, and value an established Trustpilot track record.

Methodology and freshness

We captured OatMeds pricing from its primary product page on September 4, 2026 (all figures primary-verified). 10Rx quarterly structure and inclusions were verified from its primary pricing page the same day, but the $299 semaglutide and $450 tirzepatide package totals come from secondary corroboration captured September 4, 2026; readers should confirm these totals at checkout. PlexusDx pricing is current as of September 5, 2026, drawn from our own published rate card. The 12-month cost calculations (prepaid per-month figures, annual totals, cycle counts) are our calculation. No invented data, no projections beyond documented rates. We do not manufacture negatives about competitors or force favorable PlexusDx outcomes where evidence does not support them.

Frequently Asked Questions

Can I switch from a prepaid package to monthly billing mid-cycle?

OatMeds documents a monthly billing option at $199 semaglutide/$229 tirzepatide, but cancellation and refund terms for prepaid packages are not published in the captured evidence. Contact OatMeds directly to ask whether unused weeks in a 12-week package can be refunded or converted. 10Rx quarterly package terms were not documented; confirm refund and cancellation policies at enrollment.

Does 10Rx charge the same price at all dose strengths?

Yes. 10Rx states "same package price across available strengths" for both semaglutide and tirzepatide. Whether you are starting at a low dose or maintaining at a high dose, the quarterly package costs $299 semaglutide or $450 tirzepatide. This flat pricing removes dose-escalation budget surprises.

Why is PlexusDx more expensive annually than the prepaid packages?

PlexusDx spreads cost evenly over 12 months with no upfront commitment beyond the current month. The prepaid models (OatMeds 12-week, 10Rx quarterly) require $297–$499 cash outlay every three months in exchange for a lower annual total. PlexusDx prioritizes monthly flexibility and predictable billing over maximum annual discount.

What formulation options does OatMeds offer beyond no-additive?

OatMeds compounds semaglutide and tirzepatide with B12 or with glycine, available on monthly billing at an introductory rate of $179/month with a standard refill rate of $199/month (captured September 4, 2026). The 12-week package pricing shown in this article applies to the no-additive versions. If you prefer B12 or glycine, confirm package pricing directly with OatMeds.

Are the 10Rx package totals confirmed or estimated?

The $299 semaglutide and $450 tirzepatide quarterly totals are secondary-corroborated figures captured September 4, 2026. 10Rx's primary pricing page confirmed the quarterly structure, flat-strength policy, and included services but did not display these numeric totals. We report them here because secondary corroboration is standard practice, but you should confirm at checkout before committing.

Sources

• OatMeds GLP-1 Treatments product page, https://oatmeds.com/products/glp1-treatments, accessed September 4, 2026.
• 10Rx Pricing page, https://www.take10rx.com/pricing, accessed September 4, 2026 (structure and inclusions primary-verified; package totals secondary-corroborated).
• PlexusDx rate card, https://plexusdx.com, accessed September 5, 2026.
• Trustpilot PlexusDx profile, accessed September 4, 2026.

Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.