Last reviewed: September 5, 2026 Last updated: September 5, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

PlushCare and Levity operate fundamentally different business models for GLP-1 access. PlushCare is a telehealth visit platform: you pay a $19.99 monthly membership (first 30 days free) plus a $129 initial visit, and the provider sends your prescription to an external pharmacy where you pay separately—either through insurance, manufacturer coupons, or retail cash pricing typically $900–$1,600 per month for branded medications. Levity bundles everything: medication, consult, care, and shipping in a single all-inclusive rate of $1,199 per month for Ozempic, $1,299 for Mounjaro, or $1,599 for Wegovy. PlushCare's total cost depends entirely on your pharmacy coverage; Levity's cost is fixed and predictable but paid entirely out-of-pocket. Neither model resembles PlexusDx's flat-rate compounded semaglutide at $189 per month or tirzepatide at $289, which include medication, provider oversight, and shipping with no membership fee.

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At-a-glance comparison

Feature PlushCare Levity PlexusDx
Business model Telehealth visit platform; Rx sent to external pharmacy All-inclusive: branded medication + consult + care + shipping All-inclusive: compounded medication + provider + shipping
Medication type FDA-approved branded: Wegovy, Ozempic, Mounjaro, Zepbound, Saxenda FDA-approved branded: Wegovy, Ozempic, Mounjaro; compounded liraglutide Compounded semaglutide and tirzepatide (not FDA-approved)
Service fees $19.99/month membership (first 30 days free); $129 initial visit $0 membership; all costs bundled in medication price $0 membership; all costs included in medication price
Medication cost (ongoing) Paid separately at your pharmacy; varies by insurance/coverage Ozempic $1,199/month; Mounjaro $1,299/month; Wegovy $1,599/month Semaglutide $189/month; tirzepatide $289/month
Insurance interaction Patient uses own pharmacy benefits for medication Self-pay only; no insurance billing Self-pay only; no insurance billing
12-month cost (our calculation) Service: $278 (annual membership + visit); medication cost variable Ozempic $14,338; Mounjaro $15,538; Wegovy $19,138 Semaglutide $2,268; tirzepatide $3,468
Cancellation Cancel anytime Cancel anytime Cancel anytime

All pricing captured September 4, 2026. PlexusDx pricing reflects month-to-month compounded medication programs.

Normalized cost over 12 months

PlushCare: Service fees only

PlushCare charges for access to licensed providers who can prescribe FDA-approved GLP-1 medications; the medication itself is filled and paid for at an external pharmacy of your choice.

Service cost breakdown:

  • Membership: $19.99 per month (first 30 days free), or $149 annual prepaid (our calculation: works out to $12.42/month)
  • Initial self-pay visit: $129
  • Using the annual membership option: $149 + $129 = $278 total service cost over 12 months

Medication cost: Not included. You pay your pharmacy separately, and the price depends on whether you have insurance coverage, qualify for manufacturer discount cards (Wegovy Savings Offer, Mounjaro Savings Card, etc.), or pay retail cash pricing. Retail prices for branded GLP-1 medications typically range from $900 to $1,600 per month without coverage or coupons.

Because PlushCare does not supply medication, total cost cannot be calculated without your specific pharmacy and insurance details. The $278 annual service fee is the minimum you will pay; medication adds $10,800–$19,200 annually at typical retail rates if paying cash.

Levity: All-inclusive branded medication

Levity bundles medication, consult, care, and shipping into a single monthly charge. All prices below reflect ongoing monthly rates; Levity offers a first-month introductory rate with promotional code WELCOME that is $50 lower than the standard rate for each medication (captured September 4, 2026).

Ozempic (semaglutide, FDA-approved for type 2 diabetes):

  • Standard rate: $1,199 per month
  • First-month introductory rate with code WELCOME: $1,149
  • 12-month total: $1,149 + ($1,199 × 11) = $14,338 (our calculation)
  • Effective monthly average: $1,194.83

Mounjaro (tirzepatide, FDA-approved for type 2 diabetes):

  • Standard rate: $1,299 per month
  • First-month introductory rate with code WELCOME: $1,249
  • 12-month total: $1,249 + ($1,299 × 11) = $15,538 (our calculation)
  • Effective monthly average: $1,294.83

Wegovy (semaglutide, FDA-approved for weight management):

  • Standard rate: $1,599 per month
  • First-month introductory rate with code WELCOME: $1,549
  • 12-month total: $1,549 + ($1,599 × 11) = $19,138 (our calculation)
  • Effective monthly average: $1,594.83

These prices include everything: medication, provider consultations, care coordination, and shipping. No add-on fees. Billing recurs approximately every four weeks.

PlexusDx: Compounded semaglutide and tirzepatide

PlexusDx offers compounded GLP-1 medications at fixed month-to-month rates with no membership fee, same price at every dose.

  • Compounded semaglutide injection: $189 per month; 12-month total $2,268
  • Compounded tirzepatide injection: $289 per month; 12-month total $3,468

All-inclusive: medication, provider visit, care, and shipping. Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

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Decision factors: When each model makes sense

Insurance coverage and manufacturer coupons

If your insurance covers branded GLP-1 medications—or if you qualify for manufacturer savings programs that reduce your copay to $25–$50 per month—PlushCare's visit-platform model is the clear winner. You pay the $278 annual service fee plus a small copay for medication, bringing total annual cost well below Levity's $14,000–$19,000 self-pay rates and below PlexusDx's compounded pricing.

Levity does not bill insurance for medication. Every dollar of the $1,199–$1,599 monthly charge is out-of-pocket. If you have coverage, Levity's model forfeits that benefit entirely.

Predictable self-pay pricing

If you do not have insurance coverage and are paying cash for branded medication, Levity offers cost certainty: you know exactly what you will pay each month, and the rate includes all care and shipping. Retail pharmacy pricing for the same medications—Wegovy, Ozempic, Mounjaro—ranges from $900 to $1,600 per month without coupons; Levity's bundled rates sit at the high end of that range but eliminate the need to navigate pharmacy pricing, insurance denials, or prior-authorization delays.

PlushCare's service fee is low, but your total cost is unknown until you check pharmacy pricing and insurance coverage. If your retail cost for Wegovy is $1,400 per month, PlushCare plus pharmacy equals roughly $1,420 per month (our calculation: $1,400 medication + $19.99 membership). If Levity charges $1,599 for Wegovy all-inclusive, the two models are within $180 per month of each other, but Levity eliminates the administrative friction of separate pharmacy fills, prior authorizations, and coupon renewals.

Compounded semaglutide as a cost alternative

PlexusDx's compounded semaglutide at $189 per month is 84% less expensive than Levity's Ozempic over 12 months ($2,268 vs. $14,338, our calculation) and 88% less than Levity's Wegovy ($2,268 vs. $19,138). Compounded medications are not FDA-approved and are manufactured under different regulatory standards than branded drugs, but for patients who do not require branded products and are paying out-of-pocket, the cost difference is decisive.

If cost is the primary constraint and insurance does not cover branded medications, compounded semaglutide offers the same active ingredient at a fraction of the price. A licensed clinician still reviews your eligibility, and the medication still arrives with provider oversight and care coordination.

Prior-authorization support

PlushCare advertises prior-authorization assistance, which is material if your insurance requires approval before covering a GLP-1 prescription. Levity does not interact with insurance at all, so prior-authorization support is not part of the service model. If you anticipate needing help navigating insurance approvals, PlushCare's infrastructure is designed for that workflow; Levity is not.

Choose PlushCare if…

  • Your insurance covers Wegovy, Ozempic, Mounjaro, Zepbound, or Saxenda, or you qualify for manufacturer discount programs that bring your copay below $100 per month.
  • You want branded FDA-approved medications and are willing to coordinate separately with a pharmacy.
  • You need prior-authorization support to unlock insurance coverage.
  • You prefer the flexibility to fill prescriptions at any participating pharmacy and use existing pharmacy benefits.

Choose Levity if…

  • You are paying cash for branded GLP-1 medication and want a single all-inclusive monthly charge with no pharmacy coordination.
  • You value cost certainty and predictable billing over potential insurance savings.
  • You do not have insurance that covers GLP-1 medications, or your plan has been denied and you are unwilling to navigate appeals.
  • You want branded Wegovy, Ozempic, or Mounjaro without the administrative overhead of separate prescriptions, pharmacy pickups, or refill calls.

Where PlexusDx fits

PlexusDx serves patients who want compounded semaglutide or tirzepatide at a fixed, affordable rate with no membership fees and no dose-based price increases. At $189 per month for semaglutide and $289 for tirzepatide, PlexusDx sits far below both Levity's branded self-pay rates and typical retail pharmacy pricing for branded medications. You receive provider oversight, medication, and shipping in one transparent charge, billed month-to-month with no contractual commitment.

Compounded medications are not FDA-approved, are not reviewed by FDA for safety or effectiveness before marketing, and are manufactured under different regulatory standards than branded drugs. A licensed clinician determines whether compounded semaglutide or tirzepatide is appropriate for your situation. If you qualify and cost is a primary consideration, PlexusDx offers the economic advantage of compounded GLP-1 therapy without hidden fees or membership tiers.

Methodology and freshness

All PlushCare and Levity pricing, service details, and promotional offers were captured September 4, 2026, from provider websites and published plan data. PlexusDx pricing reflects current published rates as of September 5, 2026. Twelve-month cost calculations are our own arithmetic using the captured rates; we labeled all promotional or introductory pricing explicitly and paired each figure with the corresponding standard ongoing rate. Where a provider's total cost depends on external variables (insurance coverage, pharmacy pricing), we stated that dependency plainly and did not manufacture a comparable total. No cost estimate reflects insurance reimbursement, manufacturer coupon value, or patient-specific coverage, all of which vary. Readers should confirm all figures, plan inclusions, and eligibility at checkout or intake with the respective provider.

Frequently Asked Questions

Does PlushCare include the cost of GLP-1 medication?

No. PlushCare is a telehealth visit platform; providers send prescriptions to an external pharmacy where you pay separately using insurance, manufacturer coupons, or cash. The membership fee and visit charge cover clinical services only, not medication. You will pay your pharmacy's retail or covered rate for Wegovy, Ozempic, Mounjaro, Zepbound, or Saxenda in addition to PlushCare's $278 annual service cost.

Can I use insurance with Levity's branded GLP-1 program?

No. Levity's all-inclusive rates are self-pay only and do not bill insurance. If your plan covers Wegovy, Ozempic, or Mounjaro, you forfeit that benefit by using Levity and pay the full $1,199–$1,599 monthly rate out-of-pocket. If you have coverage or manufacturer coupon eligibility, PlushCare's visit-platform model is typically more cost-effective.

How much does Wegovy cost through PlushCare compared to Levity?

PlushCare charges $278 per year in service fees (our calculation: $149 annual membership plus $129 initial visit). Wegovy's retail pharmacy price typically ranges $1,300–$1,600 per month without coverage, bringing 12-month cost to roughly $15,900–$19,500 plus the $278 service fee. Levity charges $1,599 per month all-inclusive ($19,138 over 12 months, our calculation), which is comparable to PlushCare plus retail Wegovy if you have no insurance or coupons.

Is compounded semaglutide interchangeable with Wegovy or Ozempic?

No. Compounded medications contain the same active ingredient (semaglutide) but are not FDA-approved, are not reviewed by FDA for safety or effectiveness before marketing, and are manufactured under different regulatory standards than branded drugs. A licensed clinician determines whether compounded semaglutide is appropriate for you. Compounded semaglutide costs significantly less—PlexusDx charges $189 per month versus $1,199–$1,599 for branded Ozempic or Wegovy through Levity.

Which provider offers the lowest total cost for GLP-1 therapy?

If you have insurance or manufacturer coupon access, PlushCare plus a low copay is typically the least expensive path to branded GLP-1 medication. If you are paying cash without coverage, PlexusDx compounded semaglutide at $189 per month is 84–88% less expensive than Levity's branded options over 12 months (our calculation). Levity is cost-competitive with retail pharmacy Wegovy or Ozempic when paid in cash and offers administrative simplicity.

Sources

  • PlexusDx product catalog and pricing (plexusdx.com/products/semaglutide-injection, plexusdx.com/products/tirzepatide-injection), accessed September 5, 2026
  • PlushCare service model, membership pricing, and medication list (plushcare.com), captured September 4, 2026
  • Levity branded GLP-1 medication pricing (Ozempic, Mounjaro, Wegovy) and promotional offer details (levity.com), captured September 4, 2026
  • PlexusDx Trustpilot profile (4.2-star rating, 76% five-star, 81% four-star or higher), accessed September 4, 2026

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Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

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