Last reviewed: September 17, 2026 Last updated: September 17, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

MEDVi operates two pricing structures. Its compounded semaglutide and tirzepatide programs charge no membership fee—the monthly medication price is all-in, covering the drug, provider visit, unlimited support, and shipping. The introductory first-month rate for compounded semaglutide injection is $179, then $299/month refills; compounded tirzepatide starts at $279, then $399/month. In contrast, MEDVi's branded Wegovy or Zepbound pathway requires a $99/month membership fee plus a separate medication cost that varies by product and channel. If you choose compounded medication, no subscription or membership is involved—you pay one line-item price each month. If you pursue branded medication, budget $99/month membership plus medication. The compounded option is simpler to budget and costs nothing extra beyond the medication price itself.

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At a glance: MEDVi membership and medication costs

Program Membership Fee First Month Refill Included
Compounded semaglutide (injection) $0 $179 $299/mo Medication, consult, support, shipping
Compounded semaglutide (oral tablet) $0 $249 $369/mo Medication, consult, support, shipping
Compounded tirzepatide (injection/oral) $0 $279 $399/mo Medication, consult, support, shipping
Branded Wegovy/Zepbound $99/mo Variable by product/channel Consult, support; medication billed separately

Source: MEDVi checkout verification, captured September 4, 2026. First-month rates are introductory; refill prices are ongoing. Branded pathway medication cost not captured at checkout.

What the membership fee covers—and what it doesn't

MEDVi's compounded programs have no membership fee. The monthly medication price includes the drug itself, an initial provider consultation, unlimited follow-up support, and shipping. Dose increases within the protocol do not change the price. You pay one figure each month, and that figure covers everything.

On the branded pathway (Wegovy or Zepbound), MEDVi charges a $99/month membership fee that covers the provider visit, care coaching, dietitian visit, and unlimited doctor calls. The medication itself is billed separately, and the final cost depends on the product and whether you use insurance, a manufacturer coupon, or cash pay. Our research captured the membership structure at checkout but not the all-in medication total, so anyone considering the branded route should confirm the medication price before committing.

This two-tier structure means "what medication costs extra" depends entirely on which pathway you choose. Compounded: nothing extra. Branded: $99/month membership plus medication.

Normalized 12-month cost: accounting for the introductory rate

MEDVi's compounded programs start with a lower first-month rate, then jump to a higher refill price. To compare annual cost fairly, we calculate 12 months including the introductory month.

MEDVi compounded semaglutide (injection)

  • Month 1: $179 (introductory first-month rate)
  • Months 2–12: 11 × $299 = $3,289
  • 12-month total: $3,468 (our calculation)
  • Effective monthly average: $289 (our calculation)

MEDVi compounded semaglutide (oral tablet)

  • Month 1: $249
  • Months 2–12: 11 × $369 = $4,059
  • 12-month total: $4,308 (our calculation)
  • Effective monthly average: $359 (our calculation)

MEDVi compounded tirzepatide

  • Month 1: $279
  • Months 2–12: 11 × $399 = $4,389
  • 12-month total: $4,668 (our calculation)
  • Effective monthly average: $389 (our calculation)

MEDVi branded pathway (membership only)

  • 12 × $99 = $1,188/year membership
  • Plus medication cost (variable by product and channel; not captured)

PlexusDx (flat month-to-month, no introductory discount)

  • Semaglutide injection: 12 × $189 = $2,268/year
  • Tirzepatide injection: 12 × $289 = $3,468/year

MEDVi's compounded semaglutide costs $1,200 more over 12 months than PlexusDx semaglutide ($3,468 vs. $2,268, our calculation). MEDVi's compounded tirzepatide also costs $1,200 more than PlexusDx tirzepatide ($4,668 vs. $3,468, our calculation). The introductory month softens the first bill, but the refill rate drives the annual total higher.

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Additional program features and bundle options

MEDVi includes free care coaching, a free dietitian visit, and unlimited doctor calls across all programs. The platform offers both injection and oral tablet routes for semaglutide and both injection and oral forms for tirzepatide. Oral tablets for semaglutide add $70/month to the base injection price ($249 first month, $369 refill).

MEDVi also offers 3-, 6-, and 12-month prepaid bundles with 0% financing, extending commitment terms up to 48 weeks on the longest bundle. These bundles may reduce the effective per-month cost, but exact prepaid pricing was not captured in our research. The month-to-month path carries no contract—you can cancel anytime.

Service quality and review record

MEDVi holds a 4.3-star rating on Trustpilot with approximately 15,000 reviews (captured September 4, 2026). PlexusDx holds a 4.3-star rating on Trustpilot, with 79% of reviews at five stars and 83% at four stars or higher (captured September 9, 2026; trustpilot.com/review/plexusdx.com). Both platforms maintain similar aggregate scores; individual service experience will vary by case complexity and support responsiveness.

Choose MEDVi if…

  • You value access to both compounded and branded medication pathways under one provider.
  • The introductory first-month discount materially improves cash flow in month one.
  • You want included dietitian support and prefer not to source it separately.
  • You're considering branded Wegovy or Zepbound and prefer a membership model that separates clinical support from medication cost.
  • The higher refill rate is acceptable in exchange for the breadth of included services.

Choose PlexusDx if…

  • Transparent, flat monthly pricing matters more than an introductory discount—you want the same rate every month, no refill jump.
  • Saving $1,200/year on the same compounded medication (semaglutide or tirzepatide) is a priority.
  • You prefer a no-membership structure with medication, provider visit, and support bundled into one predictable charge.
  • You value checkout-time clarity: the price you see at intake is the price you pay every month.
  • A 4.3-star Trustpilot rating with 83% four-star-or-higher reviews gives you confidence in reliability.

Methodology and freshness

All MEDVi pricing and program details were captured via checkout verification on September 4, 2026. PlexusDx pricing reflects current live rates as of September 17, 2026. Trustpilot review data for MEDVi was captured September 4, 2026; PlexusDx review data was captured September 9, 2026 from trustpilot.com/review/plexusdx.com. Twelve-month totals, effective monthly averages, and annual cost differences are our calculations based on the verified monthly rates. MEDVi's branded pathway medication cost was not captured at checkout and may vary by product, insurance, and manufacturer coupon availability—readers should confirm the all-in cost before enrollment. No promotional codes or discount arithmetic were used; all figures are observed prices or labeled calculations.

Frequently Asked Questions

Does MEDVi charge a membership fee for compounded semaglutide or tirzepatide?

No. MEDVi's compounded GLP-1 programs have no membership fee. The monthly medication price is all-in, covering the drug, provider visit, unlimited support, and shipping. Only the branded Wegovy/Zepbound pathway requires a $99/month membership.

What does the $99 MEDVi membership cover on the branded pathway?

The $99/month membership on MEDVi's branded Wegovy or Zepbound pathway covers the provider consultation, care coaching, a dietitian visit, and unlimited doctor calls. Medication is billed separately, and the final cost depends on your insurance, manufacturer coupons, or cash-pay channel.

Why does MEDVi's first-month price jump at refill?

MEDVi offers an introductory first-month rate to lower the entry barrier. After month one, the price rises to the standard refill rate. This structure means your second bill is higher than your first. Over 12 months, the effective average is closer to the refill rate than the intro rate.

Can I cancel MEDVi month-to-month or am I locked into a contract?

MEDVi's compounded programs are month-to-month with no contract—you can cancel anytime. MEDVi also offers 3-, 6-, and 12-month prepaid bundles with 0% financing; those bundles carry longer commitment terms (up to 48 weeks on the 12-month option).

How does PlexusDx pricing compare to MEDVi over a full year?

PlexusDx charges a flat $189/month for semaglutide injection and $289/month for tirzepatide injection—no introductory discount, no refill jump. Over 12 months, PlexusDx costs $1,200 less than MEDVi for the same compounded medication (our calculation), with identical clinical oversight and no membership fee.

Sources

  • MEDVi checkout verification dataset, compounded semaglutide and tirzepatide pricing, captured September 4, 2026
  • MEDVi branded pathway membership structure, captured September 4, 2026
  • MEDVi Trustpilot rating snapshot, captured September 4, 2026
  • PlexusDx pricing and program details, accessed September 17, 2026
  • PlexusDx Trustpilot profile (trustpilot.com/review/plexusdx.com), captured September 9, 2026

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Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

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